CL2019000792A1 - Implante óseo - Google Patents

Implante óseo

Info

Publication number
CL2019000792A1
CL2019000792A1 CL2019000792A CL2019000792A CL2019000792A1 CL 2019000792 A1 CL2019000792 A1 CL 2019000792A1 CL 2019000792 A CL2019000792 A CL 2019000792A CL 2019000792 A CL2019000792 A CL 2019000792A CL 2019000792 A1 CL2019000792 A1 CL 2019000792A1
Authority
CL
Chile
Prior art keywords
weight
bone implant
biocompatible polymer
porous body
bioactive glass
Prior art date
Application number
CL2019000792A
Other languages
English (en)
Inventor
Ollila Fredrik
Lindfors Nina
Björkenheim Robert
STRÖMBERG Gustav
HUPA Leena
UPPSTU Peter
PAJARINEN Jukka
Original Assignee
Bonalive Biomaterials Oy
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bonalive Biomaterials Oy filed Critical Bonalive Biomaterials Oy
Publication of CL2019000792A1 publication Critical patent/CL2019000792A1/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/02—Inorganic materials
    • A61L27/10—Ceramics or glasses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02—Prostheses implantable into the body
    • A61F2/28—Bones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02—Prostheses implantable into the body
    • A61F2/30—Joints
    • A61F2/3094—Designing or manufacturing processes
    • A61F2/30942—Designing or manufacturing processes for designing or making customized prostheses, e.g. using templates, CT or NMR scans, finite-element analysis or CAD-CAM techniques
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/28—Materials for coating prostheses
    • A61L27/34—Macromolecular materials
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L27/54—Biologically active materials, e.g. therapeutic substances
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L27/56—Porous materials, e.g. foams or sponges
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02—Prostheses implantable into the body
    • A61F2/28—Bones
    • A61F2002/2835—Bone graft implants for filling a bony defect or an endoprosthesis cavity, e.g. by synthetic material or biological material
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02—Prostheses implantable into the body
    • A61F2/30—Joints
    • A61F2002/30001—Additional features of subject-matter classified in A61F2/28, A61F2/30 and subgroups thereof
    • A61F2002/30108—Shapes
    • A61F2002/30199—Three-dimensional shapes
    • A61F2002/30224—Three-dimensional shapes cylindrical
    • A61F2002/30225—Flat cylinders, i.e. discs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02—Prostheses implantable into the body
    • A61F2/30—Joints
    • A61F2002/30001—Additional features of subject-matter classified in A61F2/28, A61F2/30 and subgroups thereof
    • A61F2002/30316—The prosthesis having different structural features at different locations within the same prosthesis; Connections between prosthetic parts; Special structural features of bone or joint prostheses not otherwise provided for
    • A61F2002/30317—The prosthesis having different structural features at different locations within the same prosthesis
    • A61F2002/30322—The prosthesis having different structural features at different locations within the same prosthesis differing in surface structures
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02—Prostheses implantable into the body
    • A61F2/30—Joints
    • A61F2/3094—Designing or manufacturing processes
    • A61F2002/30968—Sintering
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2310/00—Prostheses classified in A61F2/28 or A61F2/30 - A61F2/44 being constructed from or coated with a particular material
    • A61F2310/00005—The prosthesis being constructed from a particular material
    • A61F2310/00329—Glasses, e.g. bioglass
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2430/00—Materials or treatment for tissue regeneration
    • A61L2430/02—Materials or treatment for tissue regeneration for reconstruction of bones; weight-bearing implants

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Transplantation (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Dermatology (AREA)
  • Epidemiology (AREA)
  • Biomedical Technology (AREA)
  • Cardiology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Vascular Medicine (AREA)
  • Ceramic Engineering (AREA)
  • Inorganic Chemistry (AREA)
  • Molecular Biology (AREA)
  • Physics & Mathematics (AREA)
  • Geometry (AREA)
  • Manufacturing & Machinery (AREA)
  • Dispersion Chemistry (AREA)
  • Materials For Medical Uses (AREA)
  • Prostheses (AREA)

Abstract

Un implante óseo, CARACTERIZADO porque comprende: - un cuerpo poroso que comprende partículas de vidrio bioactivo que tienen un tamaño de partículas de al menos 500 µm, en donde la composición del vidrio bioactivo comprende 45-59% en peso de SiO2, 18-25% en peso de Na2O, 17-25% en peso de CaO y 0.1-6% en peso de P2O5, y - una película que tiene un grosor de 10 µm- 200 µm, fabricada de un polímero biocompatible y dispuesta al menos parcialmente alrededor del cuerpo. Un método de fabricación de un implante óseo que comprende formar un cuerpo poroso que comprende partículas de vidrio bioactivo, disponer una película fabricada de un polímero biocompatible al menos parcialmente alrededor del cuerpo poroso y calentar la combinación a una temperatura de transición vítrea del polímero biocompatible.
CL2019000792A 2016-10-05 2019-03-26 Implante óseo CL2019000792A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP16192500 2016-10-05

Publications (1)

Publication Number Publication Date
CL2019000792A1 true CL2019000792A1 (es) 2019-06-14

Family

ID=57103889

Family Applications (1)

Application Number Title Priority Date Filing Date
CL2019000792A CL2019000792A1 (es) 2016-10-05 2019-03-26 Implante óseo

Country Status (18)

Country Link
US (1) US12447229B2 (es)
EP (1) EP3522944B1 (es)
JP (1) JP2019535338A (es)
KR (1) KR20190073349A (es)
CN (1) CN110099700A (es)
AU (1) AU2017339120A1 (es)
BR (1) BR112019005021B1 (es)
CA (1) CA3038608A1 (es)
CL (1) CL2019000792A1 (es)
CO (1) CO2019002492A2 (es)
ES (1) ES2981552T3 (es)
FI (1) FI3522944T3 (es)
MX (1) MX2019003946A (es)
MY (1) MY201252A (es)
PE (1) PE20190858A1 (es)
PL (1) PL3522944T3 (es)
RU (1) RU2019113148A (es)
WO (1) WO2018065665A1 (es)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US11090412B2 (en) 2018-12-21 2021-08-17 Zavation Medical Products Llc Bone repair composition and kit
CN113069244A (zh) * 2021-03-31 2021-07-06 中国人民解放军空军军医大学 一种植入性具膜诱导活性的植入物包裹胶囊及其植入器
CN116036386B (zh) * 2023-02-22 2024-04-30 天津纳博特医疗器械有限公司 一种可吸收玻纤增强聚乳酸复合材料及颅颌面钉板系统
GB202414823D0 (en) * 2024-10-09 2024-11-20 Medical Res Development Fund & Health Services R N Assemblies kit-of-parts and method of constructing segmental intercalary endoprosthetic placeholder

Family Cites Families (36)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5236458A (en) * 1989-09-06 1993-08-17 S.A. Fbfc International Bioreactive material for a prosthesis or composite implants
US6149688A (en) * 1995-06-07 2000-11-21 Surgical Dynamics, Inc. Artificial bone graft implant
US5990380A (en) * 1997-10-10 1999-11-23 University Of Florida Research Foundation, Inc. Percutaneous biofixed medical implants
US6406498B1 (en) * 1998-09-04 2002-06-18 Bionx Implants Oy Bioactive, bioabsorbable surgical composite material
US6165486A (en) * 1998-11-19 2000-12-26 Carnegie Mellon University Biocompatible compositions and methods of using same
US6328990B1 (en) * 1999-11-12 2001-12-11 The Trustees Of The University Of Pennsylvania Bioactive, degradable composite for tissue engineering
US20040009228A1 (en) * 1999-11-30 2004-01-15 Pertti Tormala Bioabsorbable drug delivery system for local treatment and prevention of infections
US7488761B2 (en) * 2000-08-07 2009-02-10 Orthogen Llc Polymer containing calcium sulfate particles for bone augmentation
FI20010540A0 (fi) 2001-03-16 2001-03-16 Yli Urpo Antti Komposiitti pehmyt- ja kovakudosvammojen korjaamiseksi ja mainitun komposiitin käyttö
FI117963B (fi) * 2001-04-26 2007-05-15 Eija Marjut Pirhonen Luuta korvaavat materiaalit
WO2002087647A1 (en) 2001-04-26 2002-11-07 Eija Pirhonen Bone grafting materials
CA2447834C (en) * 2001-06-12 2010-09-14 Stick Tech Oy A prepreg, a composite and their uses
EP1433489A1 (en) 2002-12-23 2004-06-30 Degradable Solutions AG Biodegradable porous bone implant with a barrier membrane sealed thereto
US20100047309A1 (en) 2006-12-06 2010-02-25 Lu Helen H Graft collar and scaffold apparatuses for musculoskeletal tissue engineering and related methods
US20080154379A1 (en) 2006-12-22 2008-06-26 Musculoskeletal Transplant Foundation Interbody fusion hybrid graft
US8288344B2 (en) * 2007-03-15 2012-10-16 Musculoskeletal Transplant Foundation Ceramic composition for filling bone defects
WO2009094478A1 (en) * 2008-01-22 2009-07-30 Stout Medical Group, L.P. Expandable orthopedic device and method
US20090197221A1 (en) * 2008-02-04 2009-08-06 Marshall Jr Grayson W Dental bonding compositions and methods useful in inhibition of microleakage in resin-bonded dentin
CN101288780B (zh) * 2008-06-10 2011-05-25 浙江大学 可降解力学增强型生物玻璃基多孔复合材料及其制备方法
WO2010093959A2 (en) * 2009-02-12 2010-08-19 Osteotech, Inc. Delivery systems, tools, and methods of use
WO2015147923A1 (en) * 2010-03-03 2015-10-01 Novabone Products, Llc Kit for delivering bone grafting materials
SI23420A (sl) * 2010-07-22 2012-01-31 Institut "Jožef Stefan" Kostni vsadki z večslojno prevleko in postopek njihove priprave
CN102631701A (zh) 2011-09-27 2012-08-15 廖书辉 无机生物活性骨修复填充材料
RU2665361C2 (ru) * 2011-10-24 2018-08-29 СИНЕРДЖИ БАЙОМЕДИКАЛ ЭлЭлСи Композиции и их применение в регенерации костей
US8449904B1 (en) * 2012-03-26 2013-05-28 Mosci, Corp. Bioactive glass scaffolds, and method of making
ES2485381T3 (es) 2012-05-30 2014-08-13 Skulle Implants Oy Un implante
JP6416866B2 (ja) 2013-03-14 2018-10-31 プロシディアン，インコーポレーテッド 生体活性多孔性複合骨移植インプラント
US9381274B2 (en) * 2013-03-14 2016-07-05 Prosidyan, Inc. Bone graft implants containing allograft
US8889178B2 (en) * 2013-03-14 2014-11-18 Prosidyan, Inc Bioactive porous bone graft compositions in synthetic containment
US10238772B2 (en) * 2013-03-15 2019-03-26 The Curators Of The University Of Missouri Biodegradable composite scaffold for repairing defects in load-bearing bones
BR102013020961A2 (pt) * 2013-08-12 2016-03-08 Univ Fed De São Carlos composição vítrea, fibras e tecidos vítreos bioativos e artigos
US9687585B2 (en) * 2013-08-20 2017-06-27 Tepha, Inc. Thermoformed poly-4-hydroxybutyrate medical implants
US9474559B2 (en) * 2014-01-16 2016-10-25 Warsaw Orthopedic, Inc. Bone fastener with in vivo resorbable insulating coating for neuro-monitoring purposes
EP3206633A4 (en) * 2014-10-13 2018-07-18 Novabone Products LLC Irrigation resistant compositions for regeneration of hard tissues and methods and kits of using the same
EP3115025A1 (en) 2015-07-08 2017-01-11 Skulle Implants OY Orthopedic implant
US20180296450A1 (en) * 2017-04-12 2018-10-18 Vivekananda Ramana Dental whitening compositions

Also Published As

Publication number Publication date
ES2981552T3 (es) 2024-10-09
EP3522944A4 (en) 2020-06-17
PE20190858A1 (es) 2019-06-18
EP3522944B1 (en) 2024-04-03
MY201252A (en) 2024-02-13
JP2019535338A (ja) 2019-12-12
KR20190073349A (ko) 2019-06-26
EP3522944A1 (en) 2019-08-14
CO2019002492A2 (es) 2019-05-31
CA3038608A1 (en) 2018-04-12
WO2018065665A1 (en) 2018-04-12
US12447229B2 (en) 2025-10-21
MX2019003946A (es) 2019-06-10
RU2019113148A (ru) 2020-11-06
BR112019005021A2 (pt) 2019-06-04
PL3522944T3 (pl) 2024-09-16
BR112019005021B1 (pt) 2023-01-10
FI3522944T3 (fi) 2024-06-17
AU2017339120A1 (en) 2019-04-18
US20200038547A1 (en) 2020-02-06
CN110099700A (zh) 2019-08-06

Similar Documents

Publication Publication Date Title
Dziadek et al. Biodegradable ceramic-polymer composites for biomedical applications: A review
Rahaman Bioactive ceramics and glasses for tissue engineering
CO2019002492A2 (es) Un implante óseo
Baino et al. Bioceramics in ophthalmology
IN2012DN06307A (es)
BR112017002310A2 (pt) processo para preparação de uma composição particulada antimicrobiana e composição de higiene ou de cuidados pessoais
MX356872B (es) Soportes de vidrio bioactivo y metodo de fabricacion.
WO2014113779A3 (en) Molds for shaping glass and methods for making the same
UA115595C2 (uk) Спосіб отримання розчинної маси напою
MY177743A (en) Implantable paste and its use
BR112014018767A8 (pt) Compostos de pirroldicarboxamidas fundidas e composição farmacêutica que os compreende
MX374489B (es) Formulación de una composición sanguínea rica en plaquetas y/o factores de crecimiento, con proteínas gelificadas, y método de preparación de la misma.
EP4042842A4 (en) Nanosize powder advanced materials, method of manufacturing and of using same
BR112013019218A2 (pt) material particulado
MX2019012248A (es) Material regenerativo de tejidos conectivos, tal como hueso, dentina o pulpa, que comprende silicato de calcio.
BR112016028740A2 (pt) alumina mesoporosa amorfa, tendo uma conectividade elevada e o respectivo processo de preparo
MX380756B (es) Tintes biocompatibles absorbentes y reflejantes para implantes médicos de alta exactitud.
CR20200130A (es) Preparación de formas de dosificación sólida que comprenden anticuerpos por estratificación de solución/suspensión
BR112017010111A2 (pt) espaçador ("spacer") cerâmico para a troca bilateral de implantes em ombro, joelho e quadril como um resultado de infecções
Pinchuk et al. In vitro investigation of bioactive glass-ceramic composites based on biogenic hydroxyapatite or synthetic calcium phosphates
EP3564195A4 (en) COMPOSITION FOR THE PREPARATION OF GLASS, GLASS PRODUCT AND USE
ZA202000183B (en) Hydroxylapatite/gelatine composite material and the use of same, particularly as artificial ivory, and method for producing same
MX2020003809A (es) Ensamble que consiste de un par de implantes oculares multifocales.
MX2022002604A (es) Ceramica fotocatalitica.
WO2012015226A3 (en) Fabrication method of a novel artificial cortical bone using a multi-pass extrusion process