CL2020002010A1 - Uso de un polipéptido que comprende una hormona de crecimiento, y ctps adheridos a la misma, para inducir crecimiento o ganancia de peso. (divisional solicitud 201400254) - Google Patents

Uso de un polipéptido que comprende una hormona de crecimiento, y ctps adheridos a la misma, para inducir crecimiento o ganancia de peso. (divisional solicitud 201400254)

Info

Publication number
CL2020002010A1
CL2020002010A1 CL2020002010A CL2020002010A CL2020002010A1 CL 2020002010 A1 CL2020002010 A1 CL 2020002010A1 CL 2020002010 A CL2020002010 A CL 2020002010A CL 2020002010 A CL2020002010 A CL 2020002010A CL 2020002010 A1 CL2020002010 A1 CL 2020002010A1
Authority
CL
Chile
Prior art keywords
growth
polypeptide
growth hormone
weight gain
induce
Prior art date
Application number
CL2020002010A
Other languages
English (en)
Inventor
Fuad Fares
Udi Eyal Fima
Original Assignee
Opko Biologics Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Opko Biologics Ltd filed Critical Opko Biologics Ltd
Publication of CL2020002010A1 publication Critical patent/CL2020002010A1/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/22—Hormones
    • A61K38/27—Growth hormone [GH], i.e. somatotropin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/22—Hormones
    • A61K38/24—Follicle-stimulating hormone [FSH]; Chorionic gonadotropins, e.g. HCG; Luteinising hormone [LH]; Thyroid-stimulating hormone [TSH]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/04—Anorexiants; Antiobesity agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/475—Growth factors; Growth regulators
    • C07K14/505—Erythropoietin [EPO]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/59—Follicle-stimulating hormone [FSH]; Chorionic gonadotropins, e.g.hCG [human chorionic gonadotropin]; Luteinising hormone [LH]; Thyroid-stimulating hormone [TSH]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2300/00—Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Endocrinology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Biophysics (AREA)
  • Toxicology (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Immunology (AREA)
  • Epidemiology (AREA)
  • Reproductive Health (AREA)
  • Child & Adolescent Psychology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

Se describe el uso de una cantidad terapéuticamente efectiva de un polipéptido que comprende una hormona de crecimiento, un péptido de terminal carboxi de gonadotropina coriónica (CTP) adherido al terminal amino de dicha hormona de crecimiento, y dos CTPs de gonadotropina coriónica adheridos al terminal carboxi de dicha hormona de crecimiento, para inducir crecimiento o ganancia de peso en un sujeto humano.
CL2020002010A 2011-08-02 2020-07-31 Uso de un polipéptido que comprende una hormona de crecimiento, y ctps adheridos a la misma, para inducir crecimiento o ganancia de peso. (divisional solicitud 201400254) CL2020002010A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US13/195,931 US8450269B2 (en) 2006-02-03 2011-08-02 Long-acting growth hormone and methods of producing same

Publications (1)

Publication Number Publication Date
CL2020002010A1 true CL2020002010A1 (es) 2020-12-18

Family

ID=47629749

Family Applications (2)

Application Number Title Priority Date Filing Date
CL2014000254A CL2014000254A1 (es) 2011-08-02 2014-01-31 Hormona de crecimiento de accion prolongada y metodo para producir la misma
CL2020002010A CL2020002010A1 (es) 2011-08-02 2020-07-31 Uso de un polipéptido que comprende una hormona de crecimiento, y ctps adheridos a la misma, para inducir crecimiento o ganancia de peso. (divisional solicitud 201400254)

Family Applications Before (1)

Application Number Title Priority Date Filing Date
CL2014000254A CL2014000254A1 (es) 2011-08-02 2014-01-31 Hormona de crecimiento de accion prolongada y metodo para producir la misma

Country Status (23)

Country Link
US (1) US8450269B2 (es)
EP (2) EP2739298B1 (es)
JP (1) JP6153930B2 (es)
KR (3) KR20210013300A (es)
CN (2) CN104010650A (es)
AU (1) AU2012291617B2 (es)
BR (1) BR112014002491A2 (es)
CA (1) CA2843672A1 (es)
CL (2) CL2014000254A1 (es)
CO (1) CO7020850A2 (es)
DK (2) DK2739298T3 (es)
EA (2) EA202090577A3 (es)
ES (2) ES2983610T3 (es)
FI (1) FI3482765T3 (es)
HK (1) HK1200349A1 (es)
HR (1) HRP20240635T1 (es)
HU (2) HUE066552T2 (es)
MX (2) MX360802B (es)
PL (2) PL3482765T3 (es)
PT (2) PT3482765T (es)
SI (2) SI2739298T1 (es)
TR (1) TR201821186T4 (es)
WO (1) WO2013018098A2 (es)

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