CL2020002355A1 - Proteínas espiculares de virus hanta manipuladas genéticamente y sus usos. - Google Patents

Proteínas espiculares de virus hanta manipuladas genéticamente y sus usos.

Info

Publication number
CL2020002355A1
CL2020002355A1 CL2020002355A CL2020002355A CL2020002355A1 CL 2020002355 A1 CL2020002355 A1 CL 2020002355A1 CL 2020002355 A CL2020002355 A CL 2020002355A CL 2020002355 A CL2020002355 A CL 2020002355A CL 2020002355 A1 CL2020002355 A1 CL 2020002355A1
Authority
CL
Chile
Prior art keywords
spicular
proteins
genetically engineered
hanta viruses
hanta
Prior art date
Application number
CL2020002355A
Other languages
English (en)
Inventor
Tischler Nicole
Andrés Bignon Silva Eduardo
Félix Augusto Rey
Calvo Pablo Guardado
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed filed Critical
Publication of CL2020002355A1 publication Critical patent/CL2020002355A1/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/12—Viral antigens
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/525—Virus
    • A61K2039/5258—Virus-like particles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2760/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
    • C12N2760/00011—Details
    • C12N2760/12011—Bunyaviridae
    • C12N2760/12111—Hantavirus, e.g. Hantaan virus
    • C12N2760/12122—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2760/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
    • C12N2760/00011—Details
    • C12N2760/12011—Bunyaviridae
    • C12N2760/12111—Hantavirus, e.g. Hantaan virus
    • C12N2760/12134—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Virology (AREA)
  • Immunology (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Epidemiology (AREA)
  • Mycology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Microbiology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Peptides Or Proteins (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)

Abstract

ESPÍCULA HANTAVIRAL ESTABILIZADA QUE COMPRENDE AL MENOS UN HOMODÍMERO DE MUTANTES DE Gc O AL MENOS UN HETERODÍMERO DE UNA MUTANTE DE Gn Y UNA MUTANTE DE Gc O AL MENOS UN OLIGÓMERO DE MUTANTES DE Gn O UNA COMBINACIÓN DE LOS MISMOS; COMPOSICIÓN FARMACOLÓGIOCA QUE LO COMPRENDE; AGENTE DE DIAGNÓSTICO; KIT; Y SU USO.
CL2020002355A 2018-03-13 2020-09-11 Proteínas espiculares de virus hanta manipuladas genéticamente y sus usos. CL2020002355A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US201862642429P 2018-03-13 2018-03-13

Publications (1)

Publication Number Publication Date
CL2020002355A1 true CL2020002355A1 (es) 2021-08-20

Family

ID=67907312

Family Applications (1)

Application Number Title Priority Date Filing Date
CL2020002355A CL2020002355A1 (es) 2018-03-13 2020-09-11 Proteínas espiculares de virus hanta manipuladas genéticamente y sus usos.

Country Status (3)

Country Link
US (1) US11723968B2 (es)
CL (1) CL2020002355A1 (es)
WO (1) WO2019178286A1 (es)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP4688835A1 (en) * 2023-04-03 2026-02-11 Universidad Austral de Chile Single domain vhh antibodies against hantavirus

Also Published As

Publication number Publication date
US11723968B2 (en) 2023-08-15
WO2019178286A1 (en) 2019-09-19
US20210000940A1 (en) 2021-01-07

Similar Documents

Publication Publication Date Title
ECSP21052184A (es) Inhibidores de apol1 y sus métodos de uso
CO2020010303A2 (es) Conjugados de il-15, y sus usos
MX2023007852A (es) Degradadores de cinasas asociadas al receptor de interleucina-1 (irak) y usos de los mismos.
CO2023014770A2 (es) Degradadores de cdk2 y sus usos
MX2021009259A (es) Conjugados de il-2 y metodos de uso del mismo.
CO2022008662A2 (es) Degradadores de smarca y usos de los mismos
AR112969A1 (es) Conjugados de citoquina para el tratamiento de enfermedades proliferativas e infecciosas
CL2019003627A1 (es) Anticuerpos anti-pd-1 y sus usos. (solicitud divisional 201900628)
MX2020010881A (es) Construcciones de anticuerpos anti-ror.
CR10069A (es) Anticuerpos anti-ox40l y métodos que los utilizan referencia cruzada con solicitudes relacionadas
UY38403A (es) Moduladores de la alfa-1 antitripsina
MX2018015184A (es) Métodos para el diagnóstico de infecciones bacterianas y virales.
CO2021003530A2 (es) Conjugados de interleuquina 10 y usos de los mismos
MX2021006954A (es) Terapia combinada contra el virus de la hepatitis b (vhb).
CO2022003742A2 (es) Conjugados de interleuquina 10 y sus usos
CO2020001325A2 (es) Combinaciones herbicidas sinérgicas
CO2021010786A2 (es) Toxinas apxia, apxiia y apxiiia inactivadas
CL2020001197A1 (es) Combinación novedosa de defoliantes.
CO2025009897A2 (es) Degradadores de irak y usos de los mismos
AR111431A1 (es) Combinaciones de fungicidas
MX2021010254A (es) Conjugados de anticuerpo-farmaco que comprenden anticuerpos anti-tm4sf1 y metodos de uso de los mismos.
MX2020008125A (es) Composiciones que comprenden berberina.
CL2020002355A1 (es) Proteínas espiculares de virus hanta manipuladas genéticamente y sus usos.
MX2022001681A (es) Adaptador de pieza de mano para una lima endodontica.
CL2023001816A1 (es) Parapoxvirus modificado que tiene inmunogenicidad incrementada