CL2020002810A1 - Anticuerpos con perfiles de glicanos modulados - Google Patents

Anticuerpos con perfiles de glicanos modulados

Info

Publication number
CL2020002810A1
CL2020002810A1 CL2020002810A CL2020002810A CL2020002810A1 CL 2020002810 A1 CL2020002810 A1 CL 2020002810A1 CL 2020002810 A CL2020002810 A CL 2020002810A CL 2020002810 A CL2020002810 A CL 2020002810A CL 2020002810 A1 CL2020002810 A1 CL 2020002810A1
Authority
CL
Chile
Prior art keywords
antibodies
modulated
glycan profiles
glycan
profiles
Prior art date
Application number
CL2020002810A
Other languages
English (en)
Inventor
Christopher Kenyon Crowell
Jian Wu
Athena Denise Nagi
Neil Anthony Kitchen
Alison Jean Gillespie
Simina Crina Petrovan
Michael Charles Brandenstein
Original Assignee
Amgen Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=66542532&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=CL2020002810(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Amgen Inc filed Critical Amgen Inc
Publication of CL2020002810A1 publication Critical patent/CL2020002810A1/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A61K39/39591—Stabilisation, fragmentation
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0681—Cells of the genital tract; Non-germinal cells from gonads
    • C12N5/0682—Cells of the female genital tract, e.g. endometrium; Non-germinal cells from ovaries, e.g. ovarian follicle cells
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2875—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the NGF/TNF superfamily, e.g. CD70, CD95L, CD153, CD154
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/10—Immunoglobulins specific features characterized by their source of isolation or production
    • C07K2317/14—Specific host cells or culture conditions, e.g. components, pH or temperature
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
    • C07K2317/92—Affinity (KD), association rate (Ka), dissociation rate (Kd) or EC50 value
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2500/00—Specific components of cell culture medium
    • C12N2500/30—Organic components
    • C12N2500/34—Sugars

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Immunology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biomedical Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • Biochemistry (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Biotechnology (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Microbiology (AREA)
  • General Engineering & Computer Science (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Reproductive Health (AREA)
  • Cell Biology (AREA)
  • Mycology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Plant Pathology (AREA)
  • Physics & Mathematics (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Peptides Or Proteins (AREA)
CL2020002810A 2018-05-01 2020-10-29 Anticuerpos con perfiles de glicanos modulados CL2020002810A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US201862665045P 2018-05-01 2018-05-01

Publications (1)

Publication Number Publication Date
CL2020002810A1 true CL2020002810A1 (es) 2021-02-19

Family

ID=66542532

Family Applications (1)

Application Number Title Priority Date Filing Date
CL2020002810A CL2020002810A1 (es) 2018-05-01 2020-10-29 Anticuerpos con perfiles de glicanos modulados

Country Status (16)

Country Link
US (2) US12084686B2 (es)
EP (2) EP3788076A1 (es)
JP (2) JP7536651B2 (es)
KR (1) KR20250070612A (es)
CN (1) CN112074537A (es)
AU (1) AU2019263008B2 (es)
BR (1) BR112020022166A2 (es)
CA (1) CA3099163A1 (es)
CL (1) CL2020002810A1 (es)
EA (1) EA202092576A1 (es)
IL (3) IL307155B2 (es)
MA (1) MA52490A (es)
MX (1) MX2020011614A (es)
SG (1) SG11202010744YA (es)
TW (1) TW202003574A (es)
WO (1) WO2019213043A1 (es)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AR125255A1 (es) * 2021-04-02 2023-06-28 Regeneron Pharma Métodos de predicción y modulación de la glicación de una proteína
CN119452072A (zh) * 2022-06-28 2025-02-14 美国安进公司 用于治疗性产品制造的灵活的设施配置
CN117825686A (zh) * 2024-03-05 2024-04-05 军科正源（北京）药物研究有限责任公司 用于检测地诺单抗抗药性抗体的样品预处理方法及其应用

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Also Published As

Publication number Publication date
EP4316519A2 (en) 2024-02-07
US20240384238A1 (en) 2024-11-21
EP4316519A3 (en) 2024-04-24
IL307155A (en) 2023-11-01
KR20210005689A (ko) 2021-01-14
KR20250070612A (ko) 2025-05-20
EA202092576A1 (ru) 2021-02-05
US12084686B2 (en) 2024-09-10
JP7536651B2 (ja) 2024-08-20
US20210062156A1 (en) 2021-03-04
IL321253A (en) 2025-08-01
EP3788076A1 (en) 2021-03-10
IL307155B1 (en) 2025-07-01
SG11202010744YA (en) 2020-11-27
JP2024156901A (ja) 2024-11-06
MA52490A (fr) 2021-03-10
BR112020022166A2 (pt) 2021-01-26
IL278211B2 (en) 2025-11-01
TW202003574A (zh) 2020-01-16
IL278211A (en) 2020-11-30
CN112074537A (zh) 2020-12-11
IL278211B1 (en) 2023-10-01
CA3099163A1 (en) 2019-11-07
AU2019263008B2 (en) 2026-02-19
AU2019263008A1 (en) 2020-11-19
MX2020011614A (es) 2020-12-09
JP2021521854A (ja) 2021-08-30
WO2019213043A1 (en) 2019-11-07
IL307155B2 (en) 2025-11-01

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