CN101939014B - 亚硝酸盐在慢性缺血中的应用 - Google Patents

亚硝酸盐在慢性缺血中的应用 Download PDF

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Publication number
CN101939014B
CN101939014B CN200880116483.4A CN200880116483A CN101939014B CN 101939014 B CN101939014 B CN 101939014B CN 200880116483 A CN200880116483 A CN 200880116483A CN 101939014 B CN101939014 B CN 101939014B
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CN
China
Prior art keywords
nitrite
tissue
ischemic
chronic
sodium nitrite
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Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
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CN200880116483.4A
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English (en)
Chinese (zh)
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CN101939014A (zh
Inventor
克里斯托弗·凯维尔
大卫·勒费
拉凯什·帕特尔
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UAB Research Foundation
Louisiana State University
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UAB Research Foundation
Louisiana State University
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00—Medicinal preparations containing inorganic active ingredients
    • A61K33/06—Aluminium, calcium or magnesium; Compounds thereof, e.g. clay
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00—Medicinal preparations containing inorganic active ingredients
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

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  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • Inorganic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Vascular Medicine (AREA)
  • Urology & Nephrology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
CN200880116483.4A 2007-11-15 2008-11-17 亚硝酸盐在慢性缺血中的应用 Expired - Fee Related CN101939014B (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US315007P 2007-11-15 2007-11-15
US61/003,150 2007-11-15
PCT/US2008/083830 WO2009065142A2 (en) 2007-11-15 2008-11-17 Use of nitrite salts in chronic ischemia

Publications (2)

Publication Number Publication Date
CN101939014A CN101939014A (zh) 2011-01-05
CN101939014B true CN101939014B (zh) 2016-04-27

Family

ID=40639493

Family Applications (1)

Application Number Title Priority Date Filing Date
CN200880116483.4A Expired - Fee Related CN101939014B (zh) 2007-11-15 2008-11-17 亚硝酸盐在慢性缺血中的应用

Country Status (7)

Country Link
US (2) US9649334B2 (2)
EP (1) EP2219657A4 (2)
JP (2) JP5795165B2 (2)
CN (1) CN101939014B (2)
AU (1) AU2008322437B2 (2)
IL (1) IL205720A (2)
WO (1) WO2009065142A2 (2)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
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AU2008322437B2 (en) 2007-11-15 2013-11-07 Louisiana State University Use of nitrite salts in chronic ischemia
US8568793B2 (en) * 2009-02-11 2013-10-29 Hope Medical Enterprises, Inc. Sodium nitrite-containing pharmaceutical compositions
US20120237617A1 (en) 2009-06-18 2012-09-20 Theravasc Inc. Use of nitrite salts in treating tissue damage
US20130209584A1 (en) * 2009-10-14 2013-08-15 Theravasc Inc. Pharmaceutical formulations of nitrite and uses thereof
ES2633618T3 (es) 2009-10-14 2017-09-22 Theravasc Inc. Formulaciones farmacéuticas de nitrito y sus usos
WO2014130691A2 (en) * 2013-02-20 2014-08-28 Theravasc Inc. Pharmaceutical formulations of nitrite and uses thereof
US10517817B2 (en) 2013-05-09 2019-12-31 Syk Technologies, Llc Deep topical systemic nitric oxide therapy apparatus and method
ES2968200T3 (es) 2016-01-27 2024-05-08 Syk Tech Llc Aparato y métodos de aplicación tópica de óxido nítrico
JP7333919B2 (ja) 2017-09-05 2023-08-28 エクセル メッド、エルエルシー 虚血を治療するためのヘパリン組成物
PH12021551384A1 (en) 2019-01-02 2022-03-28 Celagenex Res India Pvt Ltd Synergistic nutritional compositions for pain management
US12459820B2 (en) 2020-06-11 2025-11-04 J. W. Randolph Miller Stabilized and NO2-inhibited nitric oxide generating gels for inhaled nitric oxide therapy

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US20060182815A1 (en) * 2004-07-09 2006-08-17 Use of nitrite salts for the treatment of cardiovascular conditions

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ES2633618T3 (es) 2009-10-14 2017-09-22 Theravasc Inc. Formulaciones farmacéuticas de nitrito y sus usos
US20130209584A1 (en) 2009-10-14 2013-08-15 Theravasc Inc. Pharmaceutical formulations of nitrite and uses thereof
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Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20060182815A1 (en) * 2004-07-09 2006-08-17 Use of nitrite salts for the treatment of cardiovascular conditions

Also Published As

Publication number Publication date
AU2008322437A1 (en) 2009-05-22
US10864229B2 (en) 2020-12-15
US20170312310A1 (en) 2017-11-02
IL205720A (en) 2015-08-31
JP5908527B2 (ja) 2016-04-26
JP2014139255A (ja) 2014-07-31
AU2008322437B2 (en) 2013-11-07
JP5795165B2 (ja) 2015-10-14
WO2009065142A2 (en) 2009-05-22
IL205720A0 (en) 2010-11-30
US9649334B2 (en) 2017-05-16
EP2219657A4 (en) 2020-01-08
EP2219657A2 (en) 2010-08-25
JP2011503212A (ja) 2011-01-27
US20110311653A1 (en) 2011-12-22
CN101939014A (zh) 2011-01-05

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