CN105123745A - Bactericidal composition containing dufulin and fludioxonil and bactericide - Google Patents
Bactericidal composition containing dufulin and fludioxonil and bactericide Download PDFInfo
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- CN105123745A CN105123745A CN201510466568.7A CN201510466568A CN105123745A CN 105123745 A CN105123745 A CN 105123745A CN 201510466568 A CN201510466568 A CN 201510466568A CN 105123745 A CN105123745 A CN 105123745A
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- Prior art keywords
- bactericide
- fludioxonil
- bactericidal composition
- fluorine phosphorus
- agent
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- Granted
Links
- 230000000844 anti-bacterial effect Effects 0.000 title claims abstract description 57
- 239000005781 Fludioxonil Substances 0.000 title claims abstract description 52
- MUJOIMFVNIBMKC-UHFFFAOYSA-N fludioxonil Chemical compound C=12OC(F)(F)OC2=CC=CC=1C1=CNC=C1C#N MUJOIMFVNIBMKC-UHFFFAOYSA-N 0.000 title claims abstract description 52
- 239000003899 bactericide agent Substances 0.000 title claims abstract description 41
- 239000000203 mixture Substances 0.000 title claims abstract description 38
- CLASFMUIFVKHQI-UHFFFAOYSA-N n-[diethoxyphosphoryl-(2-fluorophenyl)methyl]-4-methyl-1,3-benzothiazol-2-amine Chemical compound N=1C2=C(C)C=CC=C2SC=1NC(P(=O)(OCC)OCC)C1=CC=CC=C1F CLASFMUIFVKHQI-UHFFFAOYSA-N 0.000 title abstract 4
- 208000031888 Mycoses Diseases 0.000 claims abstract description 4
- ZHQXROVTUTVPGO-UHFFFAOYSA-N [F].[P] Chemical compound [F].[P] ZHQXROVTUTVPGO-UHFFFAOYSA-N 0.000 claims description 51
- 201000010099 disease Diseases 0.000 claims description 21
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 claims description 21
- 231100000614 poison Toxicity 0.000 claims description 21
- 239000000843 powder Substances 0.000 claims description 12
- 239000004563 wettable powder Substances 0.000 claims description 8
- 239000003905 agrochemical Substances 0.000 claims description 7
- 239000000375 suspending agent Substances 0.000 claims description 6
- 239000004562 water dispersible granule Substances 0.000 claims description 6
- 239000011248 coating agent Substances 0.000 claims description 5
- 239000008187 granular material Substances 0.000 claims description 5
- 239000000725 suspension Substances 0.000 claims description 5
- 238000009472 formulation Methods 0.000 claims description 3
- 230000007096 poisonous effect Effects 0.000 claims description 2
- 231100000572 poisoning Toxicity 0.000 claims 1
- 230000000607 poisoning effect Effects 0.000 claims 1
- 230000002195 synergetic effect Effects 0.000 abstract description 9
- 230000000694 effects Effects 0.000 abstract description 8
- 239000000575 pesticide Substances 0.000 abstract description 8
- 206010059866 Drug resistance Diseases 0.000 abstract description 2
- 230000003612 virological effect Effects 0.000 abstract description 2
- 239000003814 drug Substances 0.000 description 21
- 238000012360 testing method Methods 0.000 description 21
- 239000002574 poison Substances 0.000 description 19
- 231100000419 toxicity Toxicity 0.000 description 16
- 230000001988 toxicity Effects 0.000 description 16
- 238000000034 method Methods 0.000 description 13
- 238000002360 preparation method Methods 0.000 description 10
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- 230000003449 preventive effect Effects 0.000 description 9
- 239000003795 chemical substances by application Substances 0.000 description 8
- 238000005259 measurement Methods 0.000 description 8
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 8
- 238000009736 wetting Methods 0.000 description 8
- RCEAADKTGXTDOA-UHFFFAOYSA-N OS(O)(=O)=O.CCCCCCCCCCCC[Na] Chemical compound OS(O)(=O)=O.CCCCCCCCCCCC[Na] RCEAADKTGXTDOA-UHFFFAOYSA-N 0.000 description 7
- 241000700605 Viruses Species 0.000 description 7
- 239000002131 composite material Substances 0.000 description 7
- 240000008067 Cucumis sativus Species 0.000 description 6
- 235000010799 Cucumis sativus var sativus Nutrition 0.000 description 6
- LYCAIKOWRPUZTN-UHFFFAOYSA-N Ethylene glycol Chemical compound OCCO LYCAIKOWRPUZTN-UHFFFAOYSA-N 0.000 description 6
- 241000209094 Oryza Species 0.000 description 6
- 235000007164 Oryza sativa Nutrition 0.000 description 6
- 241000233679 Peronosporaceae Species 0.000 description 6
- VYPSYNLAJGMNEJ-UHFFFAOYSA-N Silicium dioxide Chemical compound O=[Si]=O VYPSYNLAJGMNEJ-UHFFFAOYSA-N 0.000 description 6
- 239000012752 auxiliary agent Substances 0.000 description 6
- 239000001768 carboxy methyl cellulose Substances 0.000 description 6
- 235000009566 rice Nutrition 0.000 description 6
- 238000010998 test method Methods 0.000 description 6
- 241000227653 Lycopersicon Species 0.000 description 5
- 235000007688 Lycopersicon esculentum Nutrition 0.000 description 5
- 241000607479 Yersinia pestis Species 0.000 description 5
- DPXJVFZANSGRMM-UHFFFAOYSA-N acetic acid;2,3,4,5,6-pentahydroxyhexanal;sodium Chemical compound [Na].CC(O)=O.OCC(O)C(O)C(O)C(O)C=O DPXJVFZANSGRMM-UHFFFAOYSA-N 0.000 description 5
- 239000004480 active ingredient Substances 0.000 description 5
- 238000011835 investigation Methods 0.000 description 5
- 235000019812 sodium carboxymethyl cellulose Nutrition 0.000 description 5
- 229920001027 sodium carboxymethylcellulose Polymers 0.000 description 5
- 239000005995 Aluminium silicate Substances 0.000 description 4
- RTZKZFJDLAIYFH-UHFFFAOYSA-N Diethyl ether Chemical compound CCOCC RTZKZFJDLAIYFH-UHFFFAOYSA-N 0.000 description 4
- PEDCQBHIVMGVHV-UHFFFAOYSA-N Glycerine Chemical group OCC(O)CO PEDCQBHIVMGVHV-UHFFFAOYSA-N 0.000 description 4
- DGAQECJNVWCQMB-PUAWFVPOSA-M Ilexoside XXIX Chemical compound C[C@@H]1CC[C@@]2(CC[C@@]3(C(=CC[C@H]4[C@]3(CC[C@@H]5[C@@]4(CC[C@@H](C5(C)C)OS(=O)(=O)[O-])C)C)[C@@H]2[C@]1(C)O)C)C(=O)O[C@H]6[C@@H]([C@H]([C@@H]([C@H](O6)CO)O)O)O.[Na+] DGAQECJNVWCQMB-PUAWFVPOSA-M 0.000 description 4
- 230000009471 action Effects 0.000 description 4
- 235000012211 aluminium silicate Nutrition 0.000 description 4
- LFVGISIMTYGQHF-UHFFFAOYSA-N ammonium dihydrogen phosphate Chemical compound [NH4+].OP(O)([O-])=O LFVGISIMTYGQHF-UHFFFAOYSA-N 0.000 description 4
- 229910000387 ammonium dihydrogen phosphate Inorganic materials 0.000 description 4
- 239000013530 defoamer Substances 0.000 description 4
- NLYAJNPCOHFWQQ-UHFFFAOYSA-N kaolin Chemical group O.O.O=[Al]O[Si](=O)O[Si](=O)O[Al]=O NLYAJNPCOHFWQQ-UHFFFAOYSA-N 0.000 description 4
- 235000019837 monoammonium phosphate Nutrition 0.000 description 4
- 229940051841 polyoxyethylene ether Drugs 0.000 description 4
- 229920000056 polyoxyethylene ether Polymers 0.000 description 4
- 239000011734 sodium Substances 0.000 description 4
- 229910052708 sodium Inorganic materials 0.000 description 4
- 239000000126 substance Substances 0.000 description 4
- 239000002562 thickening agent Substances 0.000 description 4
- FSLGRPCWSUDGGH-UHFFFAOYSA-N 2-methylnaphthalene-1-sulfonic acid;sodium Chemical compound [Na].C1=CC=CC2=C(S(O)(=O)=O)C(C)=CC=C21 FSLGRPCWSUDGGH-UHFFFAOYSA-N 0.000 description 3
- 241000196324 Embryophyta Species 0.000 description 3
- 210000000481 breast Anatomy 0.000 description 3
- 239000007859 condensation product Substances 0.000 description 3
- 239000002270 dispersing agent Substances 0.000 description 3
- 238000004821 distillation Methods 0.000 description 3
- 239000003995 emulsifying agent Substances 0.000 description 3
- 238000005469 granulation Methods 0.000 description 3
- 230000003179 granulation Effects 0.000 description 3
- 239000000463 material Substances 0.000 description 3
- 229920001285 xanthan gum Polymers 0.000 description 3
- 239000004372 Polyvinyl alcohol Substances 0.000 description 2
- 229920002472 Starch Polymers 0.000 description 2
- XSQUKJJJFZCRTK-UHFFFAOYSA-N Urea Chemical compound NC(N)=O XSQUKJJJFZCRTK-UHFFFAOYSA-N 0.000 description 2
- WMGSQTMJHBYJMQ-UHFFFAOYSA-N aluminum;magnesium;silicate Chemical compound [Mg+2].[Al+3].[O-][Si]([O-])([O-])[O-] WMGSQTMJHBYJMQ-UHFFFAOYSA-N 0.000 description 2
- -1 amino phosphonate ester Chemical class 0.000 description 2
- 230000008485 antagonism Effects 0.000 description 2
- 239000000440 bentonite Substances 0.000 description 2
- 229910000278 bentonite Inorganic materials 0.000 description 2
- SVPXDRXYRYOSEX-UHFFFAOYSA-N bentoquatam Chemical compound O.O=[Si]=O.O=[Al]O[Al]=O SVPXDRXYRYOSEX-UHFFFAOYSA-N 0.000 description 2
- 239000004202 carbamide Substances 0.000 description 2
- 235000012730 carminic acid Nutrition 0.000 description 2
- 238000012505 colouration Methods 0.000 description 2
- 238000012136 culture method Methods 0.000 description 2
- 238000007599 discharging Methods 0.000 description 2
- 235000011187 glycerol Nutrition 0.000 description 2
- 239000007788 liquid Substances 0.000 description 2
- 230000010534 mechanism of action Effects 0.000 description 2
- 238000002156 mixing Methods 0.000 description 2
- 239000002245 particle Substances 0.000 description 2
- ACRANQNXYMAQKJ-UHFFFAOYSA-N pestalone Chemical compound COC1=C(Cl)C(C)=C(Cl)C(O)=C1C(=O)C1=C(CC=C(C)C)C(O)=CC(O)=C1C=O ACRANQNXYMAQKJ-UHFFFAOYSA-N 0.000 description 2
- 229920005646 polycarboxylate Polymers 0.000 description 2
- 229920002451 polyvinyl alcohol Polymers 0.000 description 2
- 238000003825 pressing Methods 0.000 description 2
- 239000004576 sand Substances 0.000 description 2
- 239000002904 solvent Substances 0.000 description 2
- 238000001228 spectrum Methods 0.000 description 2
- 239000007921 spray Substances 0.000 description 2
- 239000008107 starch Substances 0.000 description 2
- 235000019698 starch Nutrition 0.000 description 2
- 238000003756 stirring Methods 0.000 description 2
- BDHFUVZGWQCTTF-UHFFFAOYSA-M sulfonate Chemical compound [O-]S(=O)=O BDHFUVZGWQCTTF-UHFFFAOYSA-M 0.000 description 2
- 239000011573 trace mineral Substances 0.000 description 2
- 235000013619 trace mineral Nutrition 0.000 description 2
- 239000000080 wetting agent Substances 0.000 description 2
- LYCAIKOWRPUZTN-NMQOAUCRSA-N 1,2-dideuteriooxyethane Chemical compound [2H]OCCO[2H] LYCAIKOWRPUZTN-NMQOAUCRSA-N 0.000 description 1
- 241000894006 Bacteria Species 0.000 description 1
- 229920002134 Carboxymethyl cellulose Polymers 0.000 description 1
- 206010011224 Cough Diseases 0.000 description 1
- YCKRFDGAMUMZLT-UHFFFAOYSA-N Fluorine atom Chemical compound [F] YCKRFDGAMUMZLT-UHFFFAOYSA-N 0.000 description 1
- WQZGKKKJIJFFOK-GASJEMHNSA-N Glucose Natural products OC[C@H]1OC(O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-GASJEMHNSA-N 0.000 description 1
- 244000061176 Nicotiana tabacum Species 0.000 description 1
- 235000002637 Nicotiana tabacum Nutrition 0.000 description 1
- 206010039509 Scab Diseases 0.000 description 1
- 230000002528 anti-freeze Effects 0.000 description 1
- 230000002507 anti-phytoviral effect Effects 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- 239000011230 binding agent Substances 0.000 description 1
- 235000010948 carboxy methyl cellulose Nutrition 0.000 description 1
- 239000008112 carboxymethyl-cellulose Substances 0.000 description 1
- 239000003153 chemical reaction reagent Substances 0.000 description 1
- 230000003247 decreasing effect Effects 0.000 description 1
- 239000007884 disintegrant Substances 0.000 description 1
- 238000001035 drying Methods 0.000 description 1
- 238000005516 engineering process Methods 0.000 description 1
- 238000011156 evaluation Methods 0.000 description 1
- 239000003337 fertilizer Substances 0.000 description 1
- 244000037666 field crops Species 0.000 description 1
- 239000000945 filler Substances 0.000 description 1
- 239000012530 fluid Substances 0.000 description 1
- 239000011737 fluorine Substances 0.000 description 1
- 229910052731 fluorine Inorganic materials 0.000 description 1
- 235000011389 fruit/vegetable juice Nutrition 0.000 description 1
- 230000000855 fungicidal effect Effects 0.000 description 1
- 239000008103 glucose Substances 0.000 description 1
- 230000002401 inhibitory effect Effects 0.000 description 1
- 238000011081 inoculation Methods 0.000 description 1
- 230000002045 lasting effect Effects 0.000 description 1
- 230000000670 limiting effect Effects 0.000 description 1
- 150000002825 nitriles Chemical class 0.000 description 1
- 239000000047 product Substances 0.000 description 1
- 238000005070 sampling Methods 0.000 description 1
- 238000010008 shearing Methods 0.000 description 1
- 238000005507 spraying Methods 0.000 description 1
- 239000003381 stabilizer Substances 0.000 description 1
- 239000013589 supplement Substances 0.000 description 1
- 230000001225 therapeutic effect Effects 0.000 description 1
- 231100000331 toxic Toxicity 0.000 description 1
- 230000002588 toxic effect Effects 0.000 description 1
- 238000012546 transfer Methods 0.000 description 1
- 238000001238 wet grinding Methods 0.000 description 1
Landscapes
- Agricultural Chemicals And Associated Chemicals (AREA)
Abstract
The invention relates to a bactericidal composition and bactericide. The bactericidal composition contains dufulin and fludioxonil. The weight ratio of dufulin to fludioxonil is (40-1):(1-60), and the preferable weight ratio of dufulin to fludioxonil is (20-1):(1-40). The provided bactericidal composition accounts for 0.1 to 80% of the total weight of bactericide. The provided bactericide has a prominent synergetic effect on controlling a plurality of crop viral and fungal diseases. The control effect is greatly improved, the using amount of pesticide is reduced, the cost is reduced, and the drug resistance is inhibited.
Description
Technical field
The present invention relates to technical field of pesticide, be specifically related to bactericidal composition and the bactericide thereof of malicious fluorine phosphorus and fludioxonil mixture.
Background technology
Poison fluorine phosphorus is that inventor is transferred the possession of the plant virus resistance product (patent No. ZL200510003041.7) of new generation come by Guizhou University, and it is a kind of novel Antiphytoviral medicament of fluorine-containing amino phosphonate ester of novel structure.The characteristics such as novel structure, the mechanism of action in view of it are unique, it is very outstanding that malicious fluorine phosphorus is used for preventing and treating virus disease effect.But its control spectrum is narrow, and it is undesirable that alone its prevents and treats other crop pest effect.For this reason, prevent and treat the control efficiency of other crop pest to improve malicious fluorine phosphorus, and delay the service life of excellent agricultural chemicals poison fluorine phosphorus, inventors performed a large amount of tests, result of the test find malicious fluorine phosphorus and the composite synergistic effect preventing and treating crop pest of fludioxonil remarkable.Different pesticide active ingredient carry out composite after, three kinds of type of action can be shown: summation action, synergistic effect and antagonism.Usually, only have by a large amount of tests just can know different pesticide active ingredient composite after type of action.
Fludioxonil is a kind of contact pesticide, can pass through the transfer suppressing glucose phosphorylated relevant, and the mycelial growth of Antifungi, finally cause germ dead, the mechanism of action is unique.Fludioxonil fungicidal spectrum is wide, has good preventive and therapeutic effect to multiple fungal disease, also may be used for control seed disease, soil-borne disease simultaneously, and cauline leaf class disease.
Up to now, the relevant report of the composition of malicious fluorine phosphorus and fludioxonil is not found at home and abroad.
Summary of the invention
By Given this, the object of the present invention is to provide bactericidal composition and bactericide, this bactericidal composition and bactericide have obvious synergistic function relative to single dose, have both decreased the dosage of agricultural chemicals, also improve the effect of preventing and treating crop pest.
To achieve these goals, technical scheme of the present invention is:
There is provided a kind of bactericidal composition, this bactericidal composition is containing poisonous fluorine phosphorus and fludioxonil, and wherein said malicious fluorine phosphorus and the weight ratio of fludioxonil are 40:1 ~ 1:60.
Preferably, described malicious fluorine phosphorus and the weight ratio of fludioxonil are 20:1 ~ 1:40.
The present invention also provides a kind of bactericide containing the bactericidal composition of malicious fluorine phosphorus described above and fludioxonil.Wherein, described bactericidal composition accounts for the 0.1%-80% of described bactericide gross weight; Preferably, described bactericidal composition accounts for the 5%-60% of described bactericide gross weight.
Bactericide provided by the invention, except comprising the Bactericidal composite beyond the region of objective existence of malicious fluorine phosphorus and fludioxonil, also can accept auxiliary element containing on agricultural chemicals.
Agricultural chemicals of the present invention can accept auxiliary element is several in wetting agent, dispersant, emulsifier, solvent, carrier.Also can add other conventional functionality auxiliary agents such as antifreeze, thickener, stabilizing agent, defoamer, disintegrant if desired.
Emulsifier, wetting agent, dispersant are sodium carboxymethylcellulose, sodium metnylene bis-naphthalene sulfonate, lauryl sodium sulfate, alkylnaphthalene sulfonate, thermally coupled distillation columns, agriculture breast 600#, the formaldehyde condensation products of methyl naphthalene sulfonic acid sodium, alkylphenol-polyethenoxy base ether, styrylphenol polyoxyethylene ether, fatty alcohol-polyoxyethylene ether, polycarboxylate.
Filler is kaolin, white carbon, bentonite, diatomite, NPK medium trace element, ammonium dihydrogen phosphate (ADP), urea.
Solvent is water.
Antifreezing agent is glycerine, ethylene glycol.
Thickener is xanthans, aluminium-magnesium silicate.
Defoamer is organosilicon.
Binding agent is starch, polyvinyl alcohol.
Warning colouration is carmine, bright red.
Bactericide provided by the invention can the multiple formulation in preparation cost field as wettable powder, missible oil, ultra low volume liquids etc.As preferably, in embodiment provided by the invention, bactericide can be prepared into following formulation: wettable powder, water dispersible granules, suspending agent, seed treatment dry powder doses, suspension seed-coating agent, granule.Wetting powder is wettable powder.
Bactericide of the present invention can be used for control crop Disease, also can be used for control crop fungal disease.
Bactericide of the present invention can be used by commonsense method, as cauline leaf spraying process, also can spread fertilizer over the fields or fill with root, can also dress seed or seed pelleting use.
Bactericidal composition provided by the invention and bactericide thereof, have following beneficial effect:
1, malicious fluorine phosphorus and the fludioxonil co-toxicity coefficient that mixture prevents and treats crop pest is within the specific limits greater than 120, shows obvious synergistic function.
2, malicious fluorine phosphorus and fludioxonil mixture reach mutual supplement with each other's advantages, improve control efficiency, and the control efficiency of each process improves more than 20% relative to the control efficiency of malicious fluorine phosphorus single dose, improves more than 20% relative to the control efficiency of fludioxonil single dose.
3, reduce the dosage of agricultural chemicals, reduce costs, go back the effect of delaying drug resistance, reduce the residual quantity of agricultural chemicals on crop simultaneously.
Embodiment
Following examples for illustration of the present invention, but are not used for limiting the scope of the invention.
The former medicine of malicious fluorine phosphorus that the present invention uses is provided by Guangxi Tianyuan Biochemical Co., Ltd., and the medicament such as fludioxonil and auxiliary agent is commercial.Former medicine calculates by folding hundred.
One, the preparation of wettable powder
Preparation method: after the auxiliary agents such as the former medicine of malicious fluorine phosphorus, the former medicine of fludioxonil, wetting dispersing agent, carrier mixing, add in cracker and be crushed to granularity and meet the requirements, discharging also stirs, and obtains the wettable powder of bactericide of the present invention.
Embodiment 1:61% poison fluorine phosphorus fludioxonil wettable powder (1:60)
Poison fluorine phosphorus 1%, fludioxonil 60%, sodium carboxymethylcellulose 2%, sodium metnylene bis-naphthalene sulfonate 3%, lauryl sodium sulfate 2%, kaolin supplies 100%.
Embodiment 2:31% poison fluorine phosphorus fludioxonil wettable powder (30:1)
Poison fluorine phosphorus 30%, fludioxonil 1%, sodium carboxymethylcellulose 4%, alkylnaphthalene sulfonate 2%, white carbon 5%, bentonite supplies 100%.
Two, the preparation of suspending agent
Preparation method: the formula rate pressing routine each embodiment, first malicious fluorine phosphorus, fludioxonil, auxiliary agent and part water are ground in sand mill, after having ground, by in material suction high-speed shearing machine, add antifreezing agent again, thickener, the water of surplus, defoamer carry out high speed shear, shear the suspending agent of rear obtained bactericide of the present invention.
Embodiment 3:21% poison fluorine phosphorus fludioxonil suspending agent (20:1)
Poison fluorine phosphorus 20%, fludioxonil 1%, thermally coupled distillation columns 6%, agriculture breast 600#3%, lauryl sodium sulfate 1%, glycerine 3%, xanthans 1.5%, organosilicon 0.05%, water supplies 100%.
Embodiment 4:30% poison fluorine phosphorus fludioxonil suspending agent (1:1)
Poison fluorine phosphorus 15%, fludioxonil 15%, thermally coupled distillation columns 4%, agriculture breast 600#5%, lauryl sodium sulfate 1%, ethylene glycol 3%, xanthans 1.5%, organosilicon 0.1%, water supplies 100%.
Three, the preparation of water dispersible granules
Preparation method: the formula rate pressing routine each embodiment, mixes each component, after airslide disintegrating mill is pulverized, stir 30min, mediate, then add in fluid bed and carry out granulation, carry out drying after granulation is good, sieve the water dispersible granules namely obtaining bactericide of the present invention.
Embodiment 5:41% poison fluorine phosphorus fludioxonil water dispersible granules (1:40)
Poison fluorine phosphorus 1%, fludioxonil 40%, sodium carboxymethylcellulose 3%, sodium metnylene bis-naphthalene sulfonate 2%, lauryl sodium sulfate 2%, starch 2%, kaolin supplies 100%.
Embodiment 6:80% poison fluorine phosphorus fludioxonil water dispersible granules (1:4)
Poison fluorine phosphorus 16%, fludioxonil 64%, the formaldehyde condensation products 5% of methyl naphthalene sulfonic acid sodium, sodium metnylene bis-naphthalene sulfonate 1%, lauryl sodium sulfate 2%, carboxymethyl cellulose 2%, diatomite supplies 100%.
Four, seed treatment dry powder doses
Preparation method: by formula rate, malicious fluorine phosphorus and fludioxonil, each auxiliary agent premixed is even, then pulverize through cracker, pulverized and again mixed, obtained the seed treatment dry powder doses of bactericide of the present invention.
Embodiment 7:12% poison fluorine phosphorus fludioxonil seed treatment dry powder doses (5:1)
Poison fluorine phosphorus 10%, fludioxonil 2%, sodium carboxymethylcellulose 6%, alkylphenol-polyethenoxy base ether 1%, polyvinyl alcohol 2%, carmine 0.2%, kaolin supplies 100%.
Five, suspension seed-coating agent
Preparation method: by formula rate by malicious fluorine phosphorus, the former medicine of fludioxonil, emulsifier mixes, add suitable quantity of water again, with sand mill wet-milling to certain particle size range, material suction is sheared in still, add film forming agent, thickener, defoamer, antifreezing agent, warning colouration and remaining water to carry out high speed shear to the index such as viscosity, particle diameter of material and meet control overflow, discharging, obtain the suspension seed-coating agent of bactericide of the present invention.
Embodiment 811% malicious fluorine phosphorus fludioxonil suspension seed-coating agent (1:10)
Poison fluorine phosphorus 1%, fludioxonil 10%, styrylphenol polyoxyethylene ether 5%, fatty alcohol-polyoxyethylene ether 2%, polycarboxylate 2%, ethylene glycol 2%, aluminium-magnesium silicate 2.5%, organosilicon 0.03%, bright red 0.2%, water supplies 100%.
Six, the preparation of granule
By formula rate, malicious fluorine phosphorus and fludioxonil, each auxiliary agent premixed is even, then pulverize through cracker, pulverized and carried out granulation, obtained the granule of bactericide of the present invention.
Embodiment 90.3% malicious fluorine phosphorus fludioxonil granule (1:2)
Poison fluorine phosphorus 0.1%, fludioxonil 0.2%, the formaldehyde condensation products 4% of methyl naphthalene sulfonic acid sodium, lauryl sodium sulfate 1.5%, NPK medium trace element 2%, ammonium dihydrogen phosphate (ADP) 5%, urea supplies 100%.
toxicity Determination:
Following indoor biometrics test adopts the abundant method of Sun Yun to calculate co-toxicity coefficient (CTC) and evaluates mixed effect.
Toxicity index TI (B)=(EC of standard agent A
50the EC of ÷ B agent
50) × 100
Actual toxicity index ATI (AB)=(EC of A
50the EC of ÷ AB
50) × 100
Theoretical toxicity index TTI (AB)=TI (the A) × A percentage+TI (B) in the mixture × percentage of B in mixture
Actual measurement toxicity index (ATI)=(standard agent EC
50÷ reagent agent EC
50) × 100
In theoretical toxicity index (TTI)=A medicament toxicity index × mixture A percentage composition+B medicament toxicity index × mixture in the percentage composition of B
Co-toxicity coefficient (CTC)=[the theoretical toxicity index (TTI) of mixture actual measurement toxicity index (ATI) ÷ mixture] × 100
Evaluation criterion is: co-toxicity coefficient >=120 show as synergistic effect; Co-toxicity coefficient≤80 show as antagonism; 80< co-toxicity coefficient <120 shows as summation action.
Toxicity Determination embodiment one
Test method: indoor pot tobacco susceptible variety plant, to the 4-5 leaf phase, with the isopyknic viral juice frictional inoculation of liquid mixing of different ratio variable concentrations, often processes 3 strains, often to select good strains in the field for seed 3 leaves, repeat 4 times, 3-4 days " Invest, Then Investigate " withered spot numbers, calculate inhibiting rate, use EC
50value is pressed the abundant method of Sun Yun and is calculated co-toxicity coefficient.Measurement result is in table 1.
The joint toxicity measuring result of tomato virus disease prevented and treated by table 1
From the measurement result of table 1, malicious fluorine phosphorus and fludioxonil composite in the scope of (40:1) ~ (1:60), the co-toxicity coefficient of control tomato virus disease all reaches more than 120, shows that both compositely have obvious synergistic effect.
Toxicity Determination embodiment two
Test method: with reference to " NY/T1156.8-2007 farm-chemical indoor determination test rule bactericide the 8th part: control rice blast pot-culture method " and " synergy of NY/T1156.6-2006 mixture measures ".Measurement result is in table 2
The joint toxicity measuring result of rice blast prevented and treated by table 2
From the measurement result of table 2, malicious fluorine phosphorus and fludioxonil composite in the scope of (40:1) ~ (1:60), the co-toxicity coefficient of control rice blast all reaches more than 120, shows that both compositely have obvious synergistic effect.
Toxicity Determination embodiment three
Test method: with reference to " NYT1156.7-2006 farm-chemical indoor determination test rule bactericide the 7th part: control cucumber downy mildew test pot-culture method " and " synergy of NY/T1156.6-2006 mixture measures ", calculate the EC of each medicament
50, and the co-toxicity coefficient of mixture is calculated according to the abundant method of Sun Yun.Measurement result is in table 3.
The joint toxicity measuring result of cucumber downy mildew prevented and treated by table 3
From the measurement result of table 3, malicious fluorine phosphorus and fludioxonil composite in the scope of (40:1) ~ (1:60), the co-toxicity coefficient of control cucumber downy mildew all reaches more than 120, shows that both compositely have obvious synergistic effect.
land for growing field crops test examples
In order to clear and definite malicious fluorine phosphorus control efficiency with when mixed prevent and treat crop pest alone with fludioxonil, present invention applicant at home different regions has carried out a large amount of field trials.
Disease index computing formula:
In formula:
X---disease index;
N
i---the sick number of sheets at different levels;
I---relative level numerical value;
N---investigate total number of sheets.
Control efficiency formula:
In formula:
P---control efficiency, unit is percentage (%);
CK
0---disease index before the dispenser of blank district;
CK
1---disease index after the dispenser of blank district;
PT
0---disease index before the dispenser of chemicals treatment district;
PT
1---disease index after dispenser after chemicals treatment;
Contrast medicament:
Contrast medicament 1:30% poison fluorine phosphorus wetting powder, registration card LS20130359, Guangxi Tianyuan Biochemical Co., Ltd.;
Contrast medicament 2:50% coughs up nitrile bacterium wetting powder, registration card PD20095400, Xian Zhengda crop protection Co., Ltd of Switzerland.
Field control effectiveness test one:
Test method and investigation method: with reference to " NY/T1464.8-2007 pesticide field efficacy medicine test criterion the 8th part: bactericidal agent for preventing and treating tomato virus disease ", before disease occurs or initial stage of origination first time spray dispenser, after 5d, second time sprays dispenser.Dispenser twice altogether, each process plot area is 20m
2, number of repetition 4 times.
Investigation method: 7d, 14d investigation before dispenser and after last dispenser, random 5 samplings in every community, get 6 strains at often, investigate total strain number, diseased plant number at different levels.Result of the test is in table 4.
The field test results of tomato virus disease prevented and treated by table 4
From result of the test table 4, at disease initial stage of origination, in the situation that active ingredient dosage is fewer than single dose, after bactericidal agent for preventing and treating tomato virus disease second time medicine of the present invention, the preventive effect of 7d and 14d is obviously better than single dose, after second time medicine, the preventive effect of 7d is respectively than the preventive effect height 20.68%-24.68% of malicious fluorine phosphorus, fludioxonil single dose, 43.80%-47.79%, after second time medicine, 14d preventive effect still can reach more than 93%, and the lasting period is long.
Field control effectiveness test two:
Test method and investigation method: with reference to " GB/T17980.19-2000 pesticide field efficacy medicine test criterion (one) bactericide paddy rice leaf diseases ".Result of the test is in table 5.
The field control effectiveness test result of rice blast prevented and treated by table 5
As shown in Table 5, when active ingredient dosage is less than contrast medicament, the preventive effect of bactericidal agent for preventing and treating rice blast of the present invention is respectively than the preventive effect height 26.23%-31.54% of single dose 30% malicious fluorine phosphorus wetting powder, 50% fludioxonil wetting powder, 20.69%-23.64%, synergy highly significant, significantly improves protection effect.
Field control effectiveness test three:
Test method and investigation method: with reference to " GB/T17980.26-2000 pesticide field efficacy medicine test criterion (): bactericidal agent for preventing and treating cucumber downy mildew ", send out front in disease or begin to carry out first time dispenser when seeing scab, second time dispenser is carried out after 5d, dispenser twice altogether, each process plot area is 20m
2, number of repetition 4 times.Result of the test is in table 6.
The field control effectiveness test result of cucumber downy mildew prevented and treated by table 6
As shown in Table 6, when active ingredient dosage is less than contrast medicament, the preventive effect of bactericidal agent for preventing and treating cucumber downy mildew of the present invention is respectively than the preventive effect height 30.80%-36.73% of single dose 30% malicious fluorine phosphorus wetting powder, 50% fludioxonil wetting powder, 21.83%-28.45%, synergy highly significant, significantly improves protection effect.
Claims (8)
1. a bactericidal composition, is characterized in that, described bactericidal composition is containing poisonous fluorine phosphorus and fludioxonil; The weight ratio of its poisoning fluorine phosphorus and fludioxonil is 40:1 ~ 1:60.
2. bactericidal composition according to claim 1, is characterized in that, the weight ratio of described malicious fluorine phosphorus and fludioxonil is 20:1 ~ 1:40.
3. the bactericide containing the arbitrary described bactericidal composition of claim 1-2, it is characterized in that, described bactericidal composition accounts for the 0.1%-80% of described bactericide gross weight.
4. bactericide according to claim 3, is characterized in that, described bactericidal composition accounts for the 5%-60% of described bactericide gross weight.
5. bactericide according to claim 3, is characterized in that, described bactericide also can accept auxiliary element containing on agricultural chemicals.
6. bactericide according to claim 3, is characterized in that, described bactericide is prepared into following formulation: wettable powder, water dispersible granules, suspending agent, seed treatment dry powder doses, suspension seed-coating agent, granule.
7. according to the application of the arbitrary described bactericide of claim 4-6 in control crop Disease.
8. according to the application of the arbitrary described bactericide of claim 4-6 in control crop fungal disease.
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Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1687088A (en) * | 2005-04-04 | 2005-10-26 | 贵州大学 | N-substituted benzothiazolyl-1-substituted phenyl-0,0-dialkyl-alpha-amino phosphonate ester derivatives preparation and application |
| WO2012177813A1 (en) * | 2011-06-24 | 2012-12-27 | Dow Agrosciences Llc | Pesticidal compositions and processes related thereto |
| CN103636668A (en) * | 2012-06-27 | 2014-03-19 | 广西田园生化股份有限公司 | Sterilization composition containing Dufulin and orysastrobin |
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Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1687088A (en) * | 2005-04-04 | 2005-10-26 | 贵州大学 | N-substituted benzothiazolyl-1-substituted phenyl-0,0-dialkyl-alpha-amino phosphonate ester derivatives preparation and application |
| WO2012177813A1 (en) * | 2011-06-24 | 2012-12-27 | Dow Agrosciences Llc | Pesticidal compositions and processes related thereto |
| CN103636668A (en) * | 2012-06-27 | 2014-03-19 | 广西田园生化股份有限公司 | Sterilization composition containing Dufulin and orysastrobin |
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