CN1058781A - 新的杂环蒽环烃同系物 - Google Patents

新的杂环蒽环烃同系物 Download PDF

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Publication number: CN1058781A
Authority: CN; China
Prior art keywords: compound; formula; group; general formula; tetrahydrochysene
Prior art date: 1990-06-11
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Pending

Application number

CN91104005A

Other languages

English (en)

Chinese (zh)

Inventor

乔吉·G·阿塔多

伯纳德·贝利奥

徐姚昌

琼·弗郎克斯·拉瓦列

拉宾达·N·赖

Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

Shire Canada Inc

Original Assignee

IAF BioChem International Inc

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1990-06-11

Filing date

1991-06-11

Publication date

1992-02-19

1991-06-11 Application filed by IAF BioChem International Inc filed Critical IAF BioChem International Inc

1992-02-19 Publication of CN1058781A publication Critical patent/CN1058781A/zh

Status Pending legal-status Critical Current

Links

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125000002948 undecyl group Chemical group [H]C([*])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H] 0.000 description 1
201000005112 urinary bladder cancer Diseases 0.000 description 1
238000001291 vacuum drying Methods 0.000 description 1
238000003828 vacuum filtration Methods 0.000 description 1
210000001215 vagina Anatomy 0.000 description 1
235000013311 vegetables Nutrition 0.000 description 1
JXLYSJRDGCGARV-CFWMRBGOSA-N vinblastine Chemical compound C([C@H](C[C@]1(C(=O)OC)C=2C(=CC3=C([C@]45[C@H]([C@@]([C@H](OC(C)=O)[C@]6(CC)C=CCN([C@H]56)CC4)(O)C(=O)OC)N3C)C=2)OC)C[C@@](C2)(O)CC)N2CCC2=C1NC1=CC=CC=C21 JXLYSJRDGCGARV-CFWMRBGOSA-N 0.000 description 1
229960003048 vinblastine Drugs 0.000 description 1
229960004528 vincristine Drugs 0.000 description 1
UGGWPQSBPIFKDZ-KOTLKJBCSA-N vindesine Chemical compound C([C@@H](C[C@]1(C(=O)OC)C=2C(=CC3=C([C@]45[C@H]([C@@]([C@H](O)[C@]6(CC)C=CCN([C@H]56)CC4)(O)C(N)=O)N3C)C=2)OC)C[C@@](C2)(O)CC)N2CCC2=C1N=C1[C]2C=CC=C1 UGGWPQSBPIFKDZ-KOTLKJBCSA-N 0.000 description 1
229960004355 vindesine Drugs 0.000 description 1
238000003809 water extraction Methods 0.000 description 1
230000003442 weekly effect Effects 0.000 description 1
RUVPNJSJTWTANE-UHFFFAOYSA-N withanolide E Natural products C1C(C)=C(C)C(=O)OC1C(C)(O)C1(O)C2(C)CCC3C4(C)C(=O)C=CCC54OC5CC3C2(O)CC1 RUVPNJSJTWTANE-UHFFFAOYSA-N 0.000 description 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D335/00—Heterocyclic compounds containing six-membered rings having one sulfur atom as the only ring hetero atom
- C07D335/04—Heterocyclic compounds containing six-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
- C07D335/06—Benzothiopyrans; Hydrogenated benzothiopyrans
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
- C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D311/76—Benzo[c]pyrans
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
- C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D311/78—Ring systems having three or more relevant rings
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D319/00—Heterocyclic compounds containing six-membered rings having two oxygen atoms as the only ring hetero atoms
- C07D319/04—1,3-Dioxanes; Hydrogenated 1,3-dioxanes
- C07D319/06—1,3-Dioxanes; Hydrogenated 1,3-dioxanes not condensed with other rings
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D327/00—Heterocyclic compounds containing rings having oxygen and sulfur atoms as the only ring hetero atoms
- C07D327/02—Heterocyclic compounds containing rings having oxygen and sulfur atoms as the only ring hetero atoms one oxygen atom and one sulfur atom
- C07D327/06—Six-membered rings
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
- C07D333/50—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
- C07D333/72—Benzo[c]thiophenes; Hydrogenated benzo[c]thiophenes
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D335/00—Heterocyclic compounds containing six-membered rings having one sulfur atom as the only ring hetero atom
- C07D335/04—Heterocyclic compounds containing six-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D407/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00
- C07D407/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings
- C07D407/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
- C07H15/20—Carbocyclic rings
- C07H15/24—Condensed ring systems having three or more rings
- C07H15/244—Anthraquinone radicals, e.g. sennosides
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
- C07H15/20—Carbocyclic rings
- C07H15/24—Condensed ring systems having three or more rings
- C07H15/252—Naphthacene radicals, e.g. daunomycins, adriamycins
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
- C07H17/04—Heterocyclic radicals containing only oxygen as ring hetero atoms
- C07H17/08—Hetero rings containing eight or more ring members, e.g. erythromycins

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
General Health & Medical Sciences (AREA)
Molecular Biology (AREA)
Genetics & Genomics (AREA)
Biotechnology (AREA)
Biochemistry (AREA)
Engineering & Computer Science (AREA)
Veterinary Medicine (AREA)
Pharmacology & Pharmacy (AREA)
Public Health (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Animal Behavior & Ethology (AREA)
Medicinal Chemistry (AREA)
General Chemical & Material Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Communicable Diseases (AREA)
Oncology (AREA)
Virology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Saccharide Compounds (AREA)
Other In-Based Heterocyclic Compounds (AREA)
Pyrane Compounds (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Heterocyclic Compounds That Contain Two Or More Ring Oxygen Atoms (AREA)
Forms Removed On Construction Sites Or Auxiliary Members Thereof (AREA)

CN91104005A 1990-06-11 1991-06-11 新的杂环蒽环烃同系物 Pending CN1058781A (zh)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US53610790A	1990-06-11	1990-06-11
US07/536,107		1990-06-11

Publications (1)

Publication Number	Publication Date
CN1058781A true CN1058781A (zh)	1992-02-19

Family

ID=24137175

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
CN91104005A Pending CN1058781A (zh)	1990-06-11	1991-06-11	新的杂环蒽环烃同系物

Country Status (18)

Country	Link
EP (1)	EP0533744A1 (fr)
JP (1)	JPH06504034A (fr)
CN (1)	CN1058781A (fr)
AP (1)	AP340A (fr)
AU (1)	AU653348B2 (fr)
CA (1)	CA2085120A1 (fr)
CS (1)	CS178691A3 (fr)
FI (1)	FI925611L (fr)
HU (1)	HU9203720D0 (fr)
IE (1)	IE911965A1 (fr)
IL (1)	IL98460A0 (fr)
MA (1)	MA22178A1 (fr)
NZ (1)	NZ238490A (fr)
PL (1)	PL297164A1 (fr)
PT (1)	PT97931A (fr)
WO (1)	WO1991019725A2 (fr)
YU (1)	YU103391A (fr)
ZA (1)	ZA914452B (fr)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
CN111087377A (zh) *	2020-03-19	2020-05-01	广东省微生物研究所（广东省微生物分析检测中心）	苯并异色满醌类化合物及其制备方法和应用

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US5606037A (en) *	1992-11-09	1997-02-25	Biochem Pharma Inc.	Processes antineoplastic heteronaphthoquinones
US5736523A (en) *	1992-11-09	1998-04-07	Biochem Pharma Inc.	Antineoplastic heteronapthoquinones
AU5414094A (en) *	1992-11-09	1994-06-08	Biochem Pharma Inc.	Antineoplastic heteronaphthoquinones
AU6672794A (en) *	1993-11-05	1995-05-23	Biochem Pharma Inc.	Antineoplastic heteronaphthoquinones
IT1271689B (it) *	1994-08-04	1997-06-04	Menarini Farma Ind	8-fluoro-antracicline, loro processi di preparazione e composizioni farmaceutiche che le contengono
EP3841123A2 (fr)	2018-08-23	2021-06-30	Seagen Inc.	Anticorps anti-tigit

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
JPS6030315B2 (ja) *	1976-06-01	1985-07-16	三井東圧化学株式会社	４−ハロゲノメチルイソクマリン誘導体の製造法
JPS52148088A (en) *	1976-06-01	1977-12-08	Richardson Merrell Inc	111aminoalkylmorphansridinee 111ols
GB2067552B (en) *	1980-01-16	1984-02-29	Erba Farmitalia	Anthracyline derivatives
CA1330560C (fr) *	1986-05-21	1994-07-05	Maurits E. A. Vandewalle	Derives di- et tetrahydroisoquinoline

1991
- 1991-06-10 FI FI925611A patent/FI925611L/fi unknown
- 1991-06-10 EP EP91910808A patent/EP0533744A1/fr not_active Ceased
- 1991-06-10 HU HU9203720A patent/HU9203720D0/hu unknown
- 1991-06-10 WO PCT/CA1991/000208 patent/WO1991019725A2/fr not_active Ceased
- 1991-06-10 PL PL29716491A patent/PL297164A1/xx unknown
- 1991-06-10 CA CA002085120A patent/CA2085120A1/fr not_active Abandoned
- 1991-06-10 AP APAP/P/1991/000278A patent/AP340A/en active
- 1991-06-10 IE IE196591A patent/IE911965A1/en unknown
- 1991-06-10 JP JP3510688A patent/JPH06504034A/ja active Pending
- 1991-06-10 AU AU80973/91A patent/AU653348B2/en not_active Ceased
- 1991-06-11 NZ NZ238490A patent/NZ238490A/en unknown
- 1991-06-11 PT PT97931A patent/PT97931A/pt not_active Application Discontinuation
- 1991-06-11 ZA ZA914452A patent/ZA914452B/xx unknown
- 1991-06-11 YU YU103391A patent/YU103391A/sh unknown
- 1991-06-11 CN CN91104005A patent/CN1058781A/zh active Pending
- 1991-06-11 MA MA22453A patent/MA22178A1/fr unknown
- 1991-06-11 CS CS911786A patent/CS178691A3/cs unknown
- 1991-06-11 IL IL98460A patent/IL98460A0/xx unknown

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
CN111087377A (zh) *	2020-03-19	2020-05-01	广东省微生物研究所（广东省微生物分析检测中心）	苯并异色满醌类化合物及其制备方法和应用

Also Published As

Publication number	Publication date
HU9203720D0 (en)	1993-03-29
NZ238490A (en)	1994-03-25
PL297164A1 (fr)	1992-10-05
AU653348B2 (en)	1994-09-29
AU8097391A (en)	1992-01-07
FI925611A0 (fi)	1992-12-10
ZA914452B (en)	1992-06-24
CS178691A3 (en)	1992-01-15
PT97931A (pt)	1992-03-31
WO1991019725A2 (fr)	1991-12-26
AP340A (en)	1994-05-13
WO1991019725A3 (fr)	1992-04-30
AP9100278A0 (en)	1991-07-31
FI925611A7 (fi)	1992-12-10
FI925611L (fi)	1992-12-10
JPH06504034A (ja)	1994-05-12
MA22178A1 (fr)	1991-12-31
IE911965A1 (en)	1991-12-18
CA2085120A1 (fr)	1991-12-12
YU103391A (sh)	1994-04-05
IL98460A0 (en)	1992-07-15
EP0533744A1 (fr)	1993-03-31

Legal Events

Date	Code	Title
1992-02-19	C06	Publication
1992-02-19	PB01	Publication
1993-09-15	C10	Entry into substantive examination
1993-09-15	SE01	Entry into force of request for substantive examination
1996-07-17	C01	Deemed withdrawal of patent application (patent law 1993)
1996-07-17	WD01	Invention patent application deemed withdrawn after publication

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CN1058781A - 新的杂环蒽环烃同系物 - Google Patents

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Applications Claiming Priority (2)

Publications (1)

Family

ID=24137175

Family Applications (1)

Country Status (18)

Cited By (1)

Families Citing this family (6)

Family Cites Families (4)

Cited By (1)

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