CN1059521A - 制备2-羟基-3-硫醚-3苯基丙酸的方法和中间体 - Google Patents

制备2-羟基-3-硫醚-3苯基丙酸的方法和中间体 Download PDF

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Publication number
CN1059521A
CN1059521A CN91108561A CN91108561A CN1059521A CN 1059521 A CN1059521 A CN 1059521A CN 91108561 A CN91108561 A CN 91108561A CN 91108561 A CN91108561 A CN 91108561A CN 1059521 A CN1059521 A CN 1059521A
Authority
CN
China
Prior art keywords
alkyl
phenyl
hydrogen
compound
alkoxy
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN91108561A
Other languages
English (en)
Chinese (zh)
Inventor
A·A·哈马斯
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
SmithKline Beecham Corp
Original Assignee
SmithKline Beecham Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by SmithKline Beecham Corp filed Critical SmithKline Beecham Corp
Publication of CN1059521A publication Critical patent/CN1059521A/zh
Pending legal-status Critical Current

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D303/00—Compounds containing three-membered rings having one oxygen atom as the only ring hetero atom
    • C07D303/02—Compounds containing oxirane rings
    • C07D303/48—Compounds containing oxirane rings with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms, e.g. ester or nitrile radicals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C319/00—Preparation of thiols, sulfides, hydropolysulfides or polysulfides
    • C07C319/14—Preparation of thiols, sulfides, hydropolysulfides or polysulfides of sulfides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Pulmonology (AREA)
  • Immunology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Epoxy Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Pyrrole Compounds (AREA)
  • Nitrogen- Or Sulfur-Containing Heterocyclic Ring Compounds With Rings Of Six Or More Members (AREA)
  • Furan Compounds (AREA)
  • Pyridine Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Pyrane Compounds (AREA)
CN91108561A 1990-08-01 1991-07-31 制备2-羟基-3-硫醚-3苯基丙酸的方法和中间体 Pending CN1059521A (zh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US56162190A 1990-08-01 1990-08-01
US561,621 1990-08-01

Publications (1)

Publication Number Publication Date
CN1059521A true CN1059521A (zh) 1992-03-18

Family

ID=24242732

Family Applications (1)

Application Number Title Priority Date Filing Date
CN91108561A Pending CN1059521A (zh) 1990-08-01 1991-07-31 制备2-羟基-3-硫醚-3苯基丙酸的方法和中间体

Country Status (23)

Country Link
US (1) US5693857A (cs)
EP (1) EP0541706B1 (cs)
JP (1) JPH06500105A (cs)
CN (1) CN1059521A (cs)
AT (1) ATE127784T1 (cs)
AU (1) AU652776B2 (cs)
BR (1) BR9106722A (cs)
CA (1) CA2088355A1 (cs)
CZ (1) CZ10593A3 (cs)
DE (1) DE69113048T2 (cs)
FI (1) FI930383A7 (cs)
HU (2) HU9401975D0 (cs)
IE (1) IE912703A1 (cs)
IL (1) IL99049A0 (cs)
MA (1) MA22482A1 (cs)
MX (1) MX9100473A (cs)
NZ (1) NZ239200A (cs)
PT (1) PT98543A (cs)
SK (1) SK5093A3 (cs)
WO (1) WO1992002519A1 (cs)
YU (1) YU134591A (cs)
ZA (1) ZA916013B (cs)
ZW (1) ZW10891A1 (cs)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2658513B1 (fr) * 1990-02-21 1994-02-04 Rhone Poulenc Sante Procede de preparation de l'acide cis-beta-phenylglycidique-(2r,3r).
US20060020142A1 (en) * 2004-07-23 2006-01-26 Pessoa Cavalcanti Fernando A Catalytic (AMM)oxidation process for conversion of lower alkanes to carboxylic acids and nitriles

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8320943D0 (en) * 1983-08-03 1983-09-07 Lilly Industries Ltd Organic compounds
US4655189A (en) * 1984-03-31 1987-04-07 Toyota Jidosha Kabushiki Kaisha Device for processing fuel vapor
US4937253A (en) * 1985-04-19 1990-06-26 Smithkline Beecham Corporation Ester prodrugs
EP0358240B1 (en) * 1985-04-19 1993-06-09 Smithkline Beecham Corporation Intermediates for the preparation of leukotriene antagonists
US4874792A (en) * 1985-04-19 1989-10-17 Smithkline Beckman Corporation Thiophenyl Alkanoic acids useful as leukotriene antagonists
CA1334200C (en) * 1987-06-24 1995-01-31 James Simpson Frazee Leukotriene antagonists
AU610528B2 (en) * 1987-10-29 1991-05-23 Smithkline Beckman Corporation Leukotriene antagonists
JP2627651B2 (ja) * 1988-10-17 1997-07-09 アネルバ株式会社 マグネトロンスパッタリング装置
US5110959A (en) * 1989-06-14 1992-05-05 Smithkline Beckman Corp. Process for preparation of epoxy esters and intermediates prepared thereby

Also Published As

Publication number Publication date
HU9401975D0 (en) 1994-09-28
FI930383A0 (fi) 1993-01-29
HU9300257D0 (en) 1993-06-28
ZA916013B (en) 1992-09-30
PT98543A (pt) 1992-06-30
BR9106722A (pt) 1993-08-31
EP0541706A4 (en) 1993-12-01
SK5093A3 (en) 1993-10-06
WO1992002519A1 (en) 1992-02-20
MA22482A1 (fr) 1992-12-31
JPH06500105A (ja) 1994-01-06
DE69113048D1 (de) 1995-10-19
ZW10891A1 (en) 1991-11-13
MX9100473A (es) 1992-04-01
HUT68410A (en) 1995-06-28
US5693857A (en) 1997-12-02
YU134591A (sh) 1994-01-20
FI930383L (fi) 1993-01-29
DE69113048T2 (de) 1996-02-22
EP0541706A1 (en) 1993-05-19
CA2088355A1 (en) 1992-02-02
CZ10593A3 (en) 1994-01-19
IL99049A0 (en) 1992-07-15
FI930383A7 (fi) 1993-01-29
ATE127784T1 (de) 1995-09-15
EP0541706B1 (en) 1995-09-13
NZ239200A (en) 1994-08-26
AU8443191A (en) 1992-03-02
AU652776B2 (en) 1994-09-08
IE912703A1 (en) 1992-02-12

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