MA22482A1 - Procede et intermediaire pour la preparation d'acides 2-hydroxy-3 thio-3-phenyl propanoiques - Google Patents

Procede et intermediaire pour la preparation d'acides 2-hydroxy-3 thio-3-phenyl propanoiques

Info

Publication number: MA22482A1
Authority: MA; Morocco
Prior art keywords: thio; hydroxy; preparation; 4alkyl; phenyl propanoic
Prior art date: 1990-08-01

Application number

MA22523A

Other languages

English (en)

Inventor

Alfonas Jarmas Alvydas

Original Assignee

Smithkline Beecham Corp

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1990-08-01

Filing date

1991-08-01

Publication date

1992-12-31

1991-08-01 Application filed by Smithkline Beecham Corp filed Critical Smithkline Beecham Corp

1992-12-31 Publication of MA22482A1 publication Critical patent/MA22482A1/fr

Links

125000004178 (C1-C4) alkyl group Chemical group 0.000 abstract 3
125000002023 trifluoromethyl group Chemical group FC(F)(F)* 0.000 abstract 3
125000000229 (C1-C4)alkoxy group Chemical group 0.000 abstract 2
QGZKDVFQNNGYKY-UHFFFAOYSA-O Ammonium Chemical compound [NH4+] QGZKDVFQNNGYKY-UHFFFAOYSA-O 0.000 abstract 1
NINIDFKCEFEMDL-UHFFFAOYSA-N Sulfur Chemical compound [S] NINIDFKCEFEMDL-UHFFFAOYSA-N 0.000 abstract 1
HSFWRNGVRCDJHI-UHFFFAOYSA-N alpha-acetylene Natural products C#C HSFWRNGVRCDJHI-UHFFFAOYSA-N 0.000 abstract 1
QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical compound [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 abstract 1
150000001875 compounds Chemical class 0.000 abstract 1
125000000113 cyclohexyl group Chemical group [H]C1([H])C([H])([H])C([H])([H])C([H])(*)C([H])([H])C1([H])[H] 0.000 abstract 1
125000002534 ethynyl group Chemical group [H]C#C* 0.000 abstract 1
125000002541 furyl group Chemical group 0.000 abstract 1
125000000555 isopropenyl group Chemical group [H]\C([H])=C(\*)C([H])([H])[H] 0.000 abstract 1
239000003199 leukotriene receptor blocking agent Substances 0.000 abstract 1
238000004519 manufacturing process Methods 0.000 abstract 1
125000001434 methanylylidene group Chemical group [H]C#[*] 0.000 abstract 1
125000002816 methylsulfanyl group Chemical group [H]C([H])([H])S[*] 0.000 abstract 1
229910052760 oxygen Inorganic materials 0.000 abstract 1
239000001301 oxygen Substances 0.000 abstract 1
125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 1
229910052717 sulfur Inorganic materials 0.000 abstract 1
239000011593 sulfur Substances 0.000 abstract 1
125000001544 thienyl group Chemical group 0.000 abstract 1
125000005034 trifluormethylthio group Chemical group FC(S*)(F)F 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D303/00—Compounds containing three-membered rings having one oxygen atom as the only ring hetero atom
- C07D303/02—Compounds containing oxirane rings
- C07D303/48—Compounds containing oxirane rings with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms, e.g. ester or nitrile radicals
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C319/00—Preparation of thiols, sulfides, hydropolysulfides or polysulfides
- C07C319/14—Preparation of thiols, sulfides, hydropolysulfides or polysulfides of sulfides

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
General Health & Medical Sciences (AREA)
Animal Behavior & Ethology (AREA)
Veterinary Medicine (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Public Health (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Engineering & Computer Science (AREA)
Pulmonology (AREA)
Immunology (AREA)
Bioinformatics & Cheminformatics (AREA)
Pain & Pain Management (AREA)
Rheumatology (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Epoxy Compounds (AREA)
Plural Heterocyclic Compounds (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
Pyrrole Compounds (AREA)
Nitrogen- Or Sulfur-Containing Heterocyclic Ring Compounds With Rings Of Six Or More Members (AREA)
Furan Compounds (AREA)
Pyridine Compounds (AREA)
Pyrane Compounds (AREA)
Investigating Or Analysing Biological Materials (AREA)

MA22523A 1990-08-01 1991-08-01 Procede et intermediaire pour la preparation d'acides 2-hydroxy-3 thio-3-phenyl propanoiques MA22482A1 (fr)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
US56162190A	1990-08-01	1990-08-01

Publications (1)

Publication Number	Publication Date
MA22482A1 true MA22482A1 (fr)	1992-12-31

Family

ID=24242732

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
MA22523A MA22482A1 (fr)	1990-08-01	1991-08-01	Procede et intermediaire pour la preparation d'acides 2-hydroxy-3 thio-3-phenyl propanoiques

Country Status (23)

Country	Link
US (1)	US5693857A (fr)
EP (1)	EP0541706B1 (fr)
JP (1)	JPH06500105A (fr)
CN (1)	CN1059521A (fr)
AT (1)	ATE127784T1 (fr)
AU (1)	AU652776B2 (fr)
BR (1)	BR9106722A (fr)
CA (1)	CA2088355A1 (fr)
CZ (1)	CZ10593A3 (fr)
DE (1)	DE69113048T2 (fr)
FI (1)	FI930383L (fr)
HU (2)	HU9401975D0 (fr)
IE (1)	IE912703A1 (fr)
IL (1)	IL99049A0 (fr)
MA (1)	MA22482A1 (fr)
MX (1)	MX9100473A (fr)
NZ (1)	NZ239200A (fr)
PT (1)	PT98543A (fr)
SK (1)	SK5093A3 (fr)
WO (1)	WO1992002519A1 (fr)
YU (1)	YU134591A (fr)
ZA (1)	ZA916013B (fr)
ZW (1)	ZW10891A1 (fr)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
FR2658513B1 (fr) *	1990-02-21	1994-02-04	Rhone Poulenc Sante	Procede de preparation de l'acide cis-beta-phenylglycidique-(2r,3r).
US20060020142A1 (en)	2004-07-23	2006-01-26	Pessoa Cavalcanti Fernando A	Catalytic (AMM)oxidation process for conversion of lower alkanes to carboxylic acids and nitriles

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
GB8320943D0 (en) *	1983-08-03	1983-09-07	Lilly Industries Ltd	Organic compounds
US4655189A (en) *	1984-03-31	1987-04-07	Toyota Jidosha Kabushiki Kaisha	Device for processing fuel vapor
EP0358240B1 (fr) *	1985-04-19	1993-06-09	Smithkline Beecham Corporation	Produits intermédiaires pour la préparation d'anagonistes de leukotriène
US4874792A (en) *	1985-04-19	1989-10-17	Smithkline Beckman Corporation	Thiophenyl Alkanoic acids useful as leukotriene antagonists
US4937253A (en) *	1985-04-19	1990-06-26	Smithkline Beecham Corporation	Ester prodrugs
CA1334200C (fr) *	1987-06-24	1995-01-31	James Simpson Frazee	Antagonistes du leucotriene
AU610528B2 (en) *	1987-10-29	1991-05-23	Smithkline Beckman Corporation	Leukotriene antagonists
JP2627651B2 (ja) *	1988-10-17	1997-07-09	アネルバ株式会社	マグネトロンスパッタリング装置
US5110959A (en) *	1989-06-14	1992-05-05	Smithkline Beckman Corp.	Process for preparation of epoxy esters and intermediates prepared thereby

1991
- 1991-07-31 HU HU9401975A patent/HU9401975D0/hu unknown
- 1991-07-31 NZ NZ239200A patent/NZ239200A/en unknown
- 1991-07-31 CZ CS93105A patent/CZ10593A3/cs unknown
- 1991-07-31 BR BR919106722A patent/BR9106722A/pt unknown
- 1991-07-31 JP JP3514490A patent/JPH06500105A/ja active Pending
- 1991-07-31 EP EP91915343A patent/EP0541706B1/fr not_active Expired - Lifetime
- 1991-07-31 DE DE69113048T patent/DE69113048T2/de not_active Expired - Fee Related
- 1991-07-31 AT AT91915343T patent/ATE127784T1/de active
- 1991-07-31 HU HU9300257A patent/HUT68410A/hu unknown
- 1991-07-31 WO PCT/US1991/005433 patent/WO1992002519A1/fr not_active Ceased
- 1991-07-31 CN CN91108561A patent/CN1059521A/zh active Pending
- 1991-07-31 IE IE270391A patent/IE912703A1/en unknown
- 1991-07-31 ZA ZA916013A patent/ZA916013B/xx unknown
- 1991-07-31 AU AU84431/91A patent/AU652776B2/en not_active Ceased
- 1991-07-31 CA CA002088355A patent/CA2088355A1/fr not_active Abandoned
- 1991-07-31 FI FI930383A patent/FI930383L/fi not_active Application Discontinuation
- 1991-08-01 IL IL99049A patent/IL99049A0/xx unknown
- 1991-08-01 PT PT98543A patent/PT98543A/pt not_active Application Discontinuation
- 1991-08-01 YU YU134591A patent/YU134591A/sh unknown
- 1991-08-01 MA MA22523A patent/MA22482A1/fr unknown
- 1991-08-01 ZW ZW108/91A patent/ZW10891A1/xx unknown
- 1991-08-01 MX MX9100473A patent/MX9100473A/es unknown
1993
- 1993-02-01 SK SK5093A patent/SK5093A3/sk unknown
1995
- 1995-04-24 US US08/428,925 patent/US5693857A/en not_active Expired - Lifetime

Also Published As

Publication number	Publication date
EP0541706A4 (en)	1993-12-01
CZ10593A3 (en)	1994-01-19
YU134591A (sh)	1994-01-20
BR9106722A (pt)	1993-08-31
FI930383A0 (fi)	1993-01-29
FI930383A7 (fi)	1993-01-29
HU9300257D0 (en)	1993-06-28
HU9401975D0 (en)	1994-09-28
WO1992002519A1 (fr)	1992-02-20
ZW10891A1 (en)	1991-11-13
CN1059521A (zh)	1992-03-18
HUT68410A (en)	1995-06-28
PT98543A (pt)	1992-06-30
DE69113048T2 (de)	1996-02-22
ZA916013B (en)	1992-09-30
FI930383L (fi)	1993-01-29
DE69113048D1 (de)	1995-10-19
AU8443191A (en)	1992-03-02
NZ239200A (en)	1994-08-26
US5693857A (en)	1997-12-02
EP0541706A1 (fr)	1993-05-19
AU652776B2 (en)	1994-09-08
IL99049A0 (en)	1992-07-15
EP0541706B1 (fr)	1995-09-13
JPH06500105A (ja)	1994-01-06
CA2088355A1 (fr)	1992-02-02
MX9100473A (es)	1992-04-01
ATE127784T1 (de)	1995-09-15
IE912703A1 (en)	1992-02-12
SK5093A3 (en)	1993-10-06

Publication	Publication Date	Title
PT95655A (pt)	1991-09-13	Processo para a preparacao de derivados de benzimidazol
DE69228727D1 (de)	1999-04-29	Verfahren zur Herstellung von gewissen Biphenyltetrazolderivaten
MA22482A1 (fr)	1992-12-31	Procede et intermediaire pour la preparation d'acides 2-hydroxy-3 thio-3-phenyl propanoiques
DE3865373D1 (de)	1991-11-14	Leukotrienantagonisten.
BR7906163A (pt)	1980-05-27	Processo para a preparacao de n-diazolil-alquil-halogeno-acetanilidas composicoes hercidas e sua aplicacao
RU93004880A (ru)	1995-03-27	Соединения и способ их получения
KR920012085A (ko)	1992-07-25	살리실알데히드 및 살리실산 유도체 및 그의 황 동족체, 이들의 제조 방법 및 그를 위한 중간체
ATE114307T1 (de)	1994-12-15	Phenylglycidamide, verwendbar in der herstellung von alpha-hydroxy-beta-sulfido-arylpropionsäure- derivaten.
ATE79873T1 (de)	1992-09-15	Leukotrien-antagonisten.
ES2063271T3 (es)	1995-01-01	Antagonistas de leucotrienos.
JPS5780366A (en)	1982-05-19	Bromodifluoromethyl sulfide and its preparation
JPS5498755A (en)	1979-08-03	Novel butenophenone derivative
KR880003911A (ko)	1988-05-31	세미카르바존 및 티오세미카르바존의 제조 방법
FR2450254A1 (fr)	1980-09-26	Nouvelles compositions pesticides a base d'esters et de thioesters d'aminoacides pour la lutte contre les insectes et leur procede d'application
KR890000415A (ko)	1989-03-14	류코트리엔 길항근
TH13534A (th)	1993-12-15	กรรมวิธีและอินเทอร์มิเดียทสำหรับเตรียม 2-ซับสทิทิวเทดเบนแซลดิไฮด์
ES469555A1 (es)	1978-12-01	Procedimiento para la preparacion de 2-bromo-3-cloro-n-2- imidazolidinilidenbenzamina y de sus sales por adicion de acido.
JPS55141470A (en)	1980-11-05	Preparation of 3,4,5-trimethoxybenzamidopyridine