CN106172425A - A kind of containing octyl trichlamide and the bactericidal composition of propiconazole and application - Google Patents
A kind of containing octyl trichlamide and the bactericidal composition of propiconazole and application Download PDFInfo
- Publication number
- CN106172425A CN106172425A CN201610598645.9A CN201610598645A CN106172425A CN 106172425 A CN106172425 A CN 106172425A CN 201610598645 A CN201610598645 A CN 201610598645A CN 106172425 A CN106172425 A CN 106172425A
- Authority
- CN
- China
- Prior art keywords
- propiconazole
- octyl trichlamide
- bactericidal composition
- trichlamide
- rot
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 239000005822 Propiconazole Substances 0.000 title claims abstract description 94
- STJLVHWMYQXCPB-UHFFFAOYSA-N propiconazole Chemical group O1C(CCC)COC1(C=1C(=CC(Cl)=CC=1)Cl)CN1N=CN=C1 STJLVHWMYQXCPB-UHFFFAOYSA-N 0.000 title claims abstract description 94
- -1 octyl trichlamide Chemical compound 0.000 title claims abstract description 66
- 239000000203 mixture Substances 0.000 title claims abstract description 52
- 230000000844 anti-bacterial effect Effects 0.000 title claims abstract description 45
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 claims abstract description 46
- 201000010099 disease Diseases 0.000 claims abstract description 38
- 235000013399 edible fruits Nutrition 0.000 claims abstract description 22
- 244000070406 Malus silvestris Species 0.000 claims abstract description 17
- 239000002552 dosage form Substances 0.000 claims abstract description 13
- 239000000375 suspending agent Substances 0.000 claims abstract description 12
- 239000004563 wettable powder Substances 0.000 claims abstract description 12
- 239000000575 pesticide Substances 0.000 claims abstract description 11
- 239000000839 emulsion Substances 0.000 claims abstract description 10
- 241000407125 Dothiorella gregaria Species 0.000 claims abstract description 9
- 240000000851 Vaccinium corymbosum Species 0.000 claims abstract description 9
- 235000003095 Vaccinium corymbosum Nutrition 0.000 claims abstract description 9
- 235000017537 Vaccinium myrtillus Nutrition 0.000 claims abstract description 9
- 235000021014 blueberries Nutrition 0.000 claims abstract description 9
- 239000004615 ingredient Substances 0.000 claims abstract description 9
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- NHTFLYKPEGXOAN-UHFFFAOYSA-N Trichlamide Chemical compound CCCCOC(C(Cl)(Cl)Cl)NC(=O)C1=CC=CC=C1O NHTFLYKPEGXOAN-UHFFFAOYSA-N 0.000 description 27
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- PXMNMQRDXWABCY-UHFFFAOYSA-N 1-(4-chlorophenyl)-4,4-dimethyl-3-(1H-1,2,4-triazol-1-ylmethyl)pentan-3-ol Chemical compound C1=NC=NN1CC(O)(C(C)(C)C)CCC1=CC=C(Cl)C=C1 PXMNMQRDXWABCY-UHFFFAOYSA-N 0.000 description 6
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- 239000005839 Tebuconazole Substances 0.000 description 6
- 239000000126 substance Substances 0.000 description 6
- QGHREAKMXXNCOA-UHFFFAOYSA-N thiophanate-methyl Chemical compound COC(=O)NC(=S)NC1=CC=CC=C1NC(=S)NC(=O)OC QGHREAKMXXNCOA-UHFFFAOYSA-N 0.000 description 6
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- FROZIYRKKUFAOC-UHFFFAOYSA-N amobam Chemical compound N.N.SC(=S)NCCNC(S)=S FROZIYRKKUFAOC-UHFFFAOYSA-N 0.000 description 3
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- OQMZNAMGEHIHNN-UHFFFAOYSA-N 7-Dehydrostigmasterol Natural products C1C(O)CCC2(C)C(CCC3(C(C(C)C=CC(CC)C(C)C)CCC33)C)C3=CC=C21 OQMZNAMGEHIHNN-UHFFFAOYSA-N 0.000 description 2
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- DNVPQKQSNYMLRS-NXVQYWJNSA-N Ergosterol Natural products CC(C)[C@@H](C)C=C[C@H](C)[C@H]1CC[C@H]2C3=CC=C4C[C@@H](O)CC[C@]4(C)[C@@H]3CC[C@]12C DNVPQKQSNYMLRS-NXVQYWJNSA-N 0.000 description 2
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- 208000008469 Peptic Ulcer Diseases 0.000 description 2
- 230000001580 bacterial effect Effects 0.000 description 2
- GAMFEMAXLMWCRG-UHFFFAOYSA-N bis(dimethylcarbamothioylsulfanyl)arsanyl n,n-dimethylcarbamodithioate Chemical compound CN(C)C(=S)S[As](SC(=S)N(C)C)SC(=S)N(C)C GAMFEMAXLMWCRG-UHFFFAOYSA-N 0.000 description 2
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- DNVPQKQSNYMLRS-SOWFXMKYSA-N ergosterol Chemical compound C1[C@@H](O)CC[C@]2(C)[C@H](CC[C@]3([C@H]([C@H](C)/C=C/[C@@H](C)C(C)C)CC[C@H]33)C)C3=CC=C21 DNVPQKQSNYMLRS-SOWFXMKYSA-N 0.000 description 2
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- QSLPNSWXUQHVLP-UHFFFAOYSA-N $l^{1}-sulfanylmethane Chemical compound [S]C QSLPNSWXUQHVLP-UHFFFAOYSA-N 0.000 description 1
- 206010003497 Asphyxia Diseases 0.000 description 1
- 235000005637 Brassica campestris Nutrition 0.000 description 1
- 241001301148 Brassica rapa subsp. oleifera Species 0.000 description 1
- 235000008733 Citrus aurantifolia Nutrition 0.000 description 1
- 229920000742 Cotton Polymers 0.000 description 1
- 244000241257 Cucumis melo Species 0.000 description 1
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- 102000004190 Enzymes Human genes 0.000 description 1
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- 244000068988 Glycine max Species 0.000 description 1
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- 244000126002 Ziziphus vulgaris Species 0.000 description 1
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- FJJCIZWZNKZHII-UHFFFAOYSA-N [4,6-bis(cyanoamino)-1,3,5-triazin-2-yl]cyanamide Chemical compound N#CNC1=NC(NC#N)=NC(NC#N)=N1 FJJCIZWZNKZHII-UHFFFAOYSA-N 0.000 description 1
- ABUGVBRDFWGJRD-CHOYNLESSA-N [9-[(2r,3r,4s,5r)-3,4-dihydroxy-5-methyloxolan-2-yl]-2-(2,4-dinitrophenyl)sulfanylpurin-6-yl] [hydroxy(phosphonooxy)phosphoryl] hydrogen phosphate Chemical compound O[C@@H]1[C@H](O)[C@@H](C)O[C@H]1N1C2=NC(SC=3C(=CC(=CC=3)[N+]([O-])=O)[N+]([O-])=O)=NC(OP(O)(=O)OP(O)(=O)OP(O)(O)=O)=C2N=C1 ABUGVBRDFWGJRD-CHOYNLESSA-N 0.000 description 1
- JNVCSEDACVAATK-UHFFFAOYSA-L [Ca+2].[S-]SSS[S-] Chemical compound [Ca+2].[S-]SSS[S-] JNVCSEDACVAATK-UHFFFAOYSA-L 0.000 description 1
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- YDEXUEFDPVHGHE-GGMCWBHBSA-L disodium;(2r)-3-(2-hydroxy-3-methoxyphenyl)-2-[2-methoxy-4-(3-sulfonatopropyl)phenoxy]propane-1-sulfonate Chemical compound [Na+].[Na+].COC1=CC=CC(C[C@H](CS([O-])(=O)=O)OC=2C(=CC(CCCS([O-])(=O)=O)=CC=2)OC)=C1O YDEXUEFDPVHGHE-GGMCWBHBSA-L 0.000 description 1
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- 235000010482 polyoxyethylene sorbitan monooleate Nutrition 0.000 description 1
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- GOLXNESZZPUPJE-UHFFFAOYSA-N spiromesifen Chemical compound CC1=CC(C)=CC(C)=C1C(C(O1)=O)=C(OC(=O)CC(C)(C)C)C11CCCC1 GOLXNESZZPUPJE-UHFFFAOYSA-N 0.000 description 1
- 235000001508 sulfur Nutrition 0.000 description 1
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Classifications
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
- A01N43/64—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with three nitrogen atoms as the only ring hetero atoms
- A01N43/647—Triazoles; Hydrogenated triazoles
- A01N43/653—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01G—HORTICULTURE; CULTIVATION OF VEGETABLES, FLOWERS, RICE, FRUIT, VINES, HOPS OR SEAWEED; FORESTRY; WATERING
- A01G13/00—Protection of plants
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01G—HORTICULTURE; CULTIVATION OF VEGETABLES, FLOWERS, RICE, FRUIT, VINES, HOPS OR SEAWEED; FORESTRY; WATERING
- A01G7/00—Botany in general
- A01G7/06—Treatment of growing trees or plants, e.g. for preventing decay of wood, for tingeing flowers or wood, for prolonging the life of plants
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N33/00—Biocides, pest repellants or attractants, or plant growth regulators containing organic nitrogen compounds
- A01N33/02—Amines; Quaternary ammonium compounds
- A01N33/04—Nitrogen directly attached to aliphatic or cycloaliphatic carbon atoms
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Environmental Sciences (AREA)
- Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Health & Medical Sciences (AREA)
- Wood Science & Technology (AREA)
- Forests & Forestry (AREA)
- Ecology (AREA)
- Biodiversity & Conservation Biology (AREA)
- Agronomy & Crop Science (AREA)
- Pest Control & Pesticides (AREA)
- Plant Pathology (AREA)
- Dentistry (AREA)
- Zoology (AREA)
- Botany (AREA)
- Toxicology (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
Abstract
The invention discloses a kind of containing octyl trichlamide with the bactericidal composition of propiconazole, effective ingredient is octyl trichlamide and propiconazole, and propiconazole is 2:1～1:30 with the weight ratio of octyl trichlamide；Can also be containing Pesticide Science allowing use and acceptable adjuvant, dosage form can be wettable powder, suspending agent, cream, aqueous emulsion, water dispersible granules or microemulsion.The bactericidal composition of the present invention, the mechanism of action of effective ingredient is entirely different, compounds and can act in sites many to pathogen, and Synergistic expands fungicidal spectrum, improves preventive effect, reduces Pesticide use amount, delays drug-fast generation, reduction resistance risk.The bactericidal composition of the present invention, for preventing and treating the multiple trunk disease on fruit tree, forest, it is particularly suited for the diseases such as canker of apple fruit, eyespot in apple limb, dry rot of apple, Fructus Pruni pseudocerasi bleeding disease, peach gummosis, blue berry branch-rot, Ramulus Juglandis rot, branch of poplar rot, dothiorella gregaria.It is alternatively arranged as fruit tree, forest grafting, the sealing compound of beta pruning.
Description
Technical field
The present invention relates to a kind of containing octyl trichlamide with the bactericidal composition of propiconazole, and sick preventing and treating fruit tree, forest branch
Evil is applied, belongs to the application of pesticide control technical field.
Background technology
Trunk disease is one of Major Diseases of fruit tree, forest, and its incidence rate, hazardness increase the weight of year by year in recent years, becomes
For harm fruit industry, the great disease of production of forestry.Fruit tree, forest trunk disease include canker, Trunk canker, bleeding disease,
The diseases such as dry rot, Peptic Ulcers, branch-rot, wherein, apple tree Trunk canker popularizing along with fruit bagging technology in recent years
Promoting generation increasingly severe, fall ill the heaviest with Fuji, red magnitude seeds, diseased plant rate reaches more than 90%；Apple tree canker
The major branch of main harm apple tree and side shoot, cause Fructus Mali pumilae tree vigo(u)r weak, and fruit yield and quality decline, serious orchard of falling ill
A large amount of dead trees even ruin garden；Widely, and its parasitics is weak, adds SPS for the host range of dothiorella gregaria pathogenic bacteria
The most capable, cause a large amount of pathogenic bacteria to be spread along with the allocation and transportation of nursery stock, cause dothiorella gregaria occur increasingly severe, particularly
Bigger to the nursery stock at the initial stage of planting and the harm of treelet, cause the death of a large amount of nursery stock, cause the failure of whole spring afforestation, according to
Report, in the area that morbidity is serious, the sickness rate of forest is up to 96.1%～100%, and dothiorella gregaria has become development China
The serious hindrance of Poplar Plantation.
In view of the order of severity of trunk disease harm, recent domestic scholar has carried out substantial amounts of research to it, and has carried
Go out many effectively preventing measures, but in today of wildness outburst, every prophylactico-therapeutic measures all difficulties have reached preferable prevention effect.
The preferable medicament asomate of the most conventional preventing and treating trunk disease belongs to high poison, persistent pesticide, and the Ministry of Agriculture is comprehensive the end of the year 2015
Forbid selling and using, and other medicaments such as lime sulfur, copper humate etc., although play a role, but exist more
Problems and shortcomings, are mainly manifested in model of action single, and prevention effect is unstable, and the aspects such as the drug effect phase is short cause general control
Effect is undesirable, and scab relapse rate is high, and wound healing is poor.Therefore, low toxicity a kind of efficiently in the urgent need to invention, environmental protection, can be thorough
End sterilization can promote again preventing and treating fruit tree, the therapeutic agent of forest trunk disease of the low cost of wound healing.
Octyl trichlamide, is a kind of environment-friendly type amino acids high molecular polymer antibacterial, be a new generation's high-tech, environment-friendly type,
High-efficiency broad spectrum, low toxicity antibacterial.The mechanism of action of octyl trichlamide is to produce ionization in aqueous, and hydrophilic group part contains strongly
Electropositive, absorption generally each bacterioid in negative electricity, virus thus inhibit antibacterial, the breeding of virus, solidification pathogenic bacteria albumen
Matter, makes pathogenic bacteria enzyme system degeneration, adds that the thin film that polymer is formed plugs the ion channel of this part microorganism so that it is immediately
Death by suffocation, thus reach optimal bactericidal effect.Broad-spectrum, has interior absorption and extremely strong permeability, also has two-way
Translocation, has protection simultaneously, treats, roots out, takes good care of four big functions.Octyl trichlamide can be used for fruit tree, vegetable, melon, Cotton Gossypii,
The various crop such as Oryza sativa L., Semen Tritici aestivi, corn and soybean, Brassica campestris L, medical material, Rhizoma Zingiberis Recens are by antibacterial, virus, fungus-caused multiple diseases
Preventing and treating.
Propiconazole (Propiconazole), and chemical name: 1-[2-2,4-Dichlorobenzene base)-4-propyl group-1,3-dioxy penta
Ring-2-methyl]-1 hydrogen-1,2,4-triazoles, chemical formula: C15H17Cl2N3O2.Propiconazole be a kind of have protection and therapeutical effect
Interior absorption triazole bactericidal agent, can be absorbed by root, stem, leaf portion, and can upwards conduct in plant body soon, belongs to ergosterol
Biosynthetic inhibitor.Ergosterol plays an important role in the composition of fungal cell membrane, and propiconazole is gone by interference C14-
Methylate and hinder the biosynthesis of ergosterol in fungus body, thus destroy the growth and breeding of fungus, play protection and treatment
Effect.There is the features such as fungicidal spectrum is extensive, activity is high, sterilization speed is fast, lasting period length, Uptake and translocation are strong, be that triazole type is killed
One of Typical Representative kind of microbial inoculum.Propiconazole is in addition to invalid to oomycetes disease, to Saccharomyces, Basidiomycotina, Dendrochium
The multiple diseases that fungus causes on cereal crops, veterinary antibiotics, forest and ornamental plant is effective, is particularly well-suited to preventing and treating
Multiple trunk disease on fruit tree, forest.
At present, there is not yet and octyl trichlamide and propiconazole have been carried out compounding use and is used for preventing and treating fruit tree, forest branch disease
The relevant report of evil.
Summary of the invention
For above-mentioned prior art, the invention provides a kind of containing octyl trichlamide with the bactericidal composition of propiconazole, and
Preventing and treating fruit tree, forest trunk disease are applied.
The present invention is achieved by the following technical solutions:
A kind of containing octyl trichlamide with the bactericidal composition of propiconazole, effective ingredient is octyl trichlamide and propiconazole, and propiconazole is with pungent
The weight ratio of bacterium amine is 2:1～1:30, it is preferred that for 1:1～15.
In the described bactericidal composition containing octyl trichlamide and propiconazole, can be containing Pesticide Science allowing use and can accept
Adjuvant.
Further, the described bactericidal composition containing octyl trichlamide and propiconazole is made up of the component of following weight portion:
Propiconazole 1%～80%, octyl trichlamide 1%～80%, surplus is to allow in Pesticide Science to use and acceptable adjuvant.
Described Pesticide Science allows use and be selected from solvent, penetrating agent, dispersant, diffusant with acceptable adjuvant, collapse
Solve agent, emulsifying agent, stabilizer, wetting agent, defoamer, antifreezing agent etc. and other contributes to the stable of effective ingredient drug effect and plays
Allow make used additives.
Described containing octyl trichlamide with the bactericidal composition of propiconazole, can be prepared as by processing method well known in the prior art
Being suitable for any one dosage form that agricultural production uses, preferred dosage form is: wettable powder, suspending agent, cream, aqueous emulsion, moisture
Shot agent, microemulsion.
The present invention containing octyl trichlamide and the bactericidal composition of propiconazole, be used for preventing and treating fruit tree, forest (apple tree, cherry tree,
Pear tree, peach tree, jujube tree, Semen Castaneae, Semen Juglandis, Caulis et folium euphorbiae milii, willow, willow etc.) on multiple trunk disease, be particularly suited for apple decay
Disease, eyespot in apple limb, dry rot of apple, Fructus Pruni pseudocerasi bleeding disease, peach gummosis, blue berry branch-rot, branch of poplar rot, willow
The diseases such as Peptic Ulcers, Ramulus Juglandis rot.Preferably, when preventing and treating Valsa mali, propiconazole and the weight of both octyl trichlamide
Ratio is preferred with 1:1～15, and more preferably, 1:5 is optimal for 1:1～10.When preventing and treating eyespot in apple limb bacterium, propiconazole and octyl trichlamide two
The weight ratio of person is preferred with 2:1～1:20, and more preferably, 1:5 is optimal for 1:5～15.When preventing and treating Fructus Pruni pseudocerasi gummosis pathogenic bacteria, propiconazole is with pungent
The weight ratio of both bacterium amine is preferred with 2:1～1:20, and more preferably, 1:5 is optimal for 1:5～15.When preventing and treating dothiorella gregaria bacterium, the third ring
Azoles is preferred with 2:1～1:20 with the weight ratio of both octyl trichlamide, and more preferably, 1:5 is optimal for 1:5～15.In preventing and treating branch of Semen Juglandis rot
During bacterium, propiconazole is preferred with 2:1～1:30 with the weight ratio of both octyl trichlamide, and more preferably, 1:5 is optimal for 1:1～20.At preventing and treating blue berry
During branch-rot bacterium, propiconazole is preferred with 1:1～25 with the weight ratio of both octyl trichlamide, and more preferably, 1:5 is optimal for 1:2～15.It addition,
The bactericidal composition containing octyl trichlamide and propiconazole of the present invention is alternatively arranged as fruit tree, forest grafting, the sealing compound of beta pruning.
Triazole bactericidal agent is the antibacterial kind that China's applicating history is longer, plays emphatically in the preventing and treating of crop pest
The effect wanted, although at present triazole type medicament is still in large-area use, but pathogen is to the sensitivity of such medicament
Through occurring in that decline by a relatively large margin, the using dosage in field gradually steps up, and environment and resistance are created bigger pressure, because of
This should carry out correlational study to slow down the generation of resistance, and using the pharmacy mix of different mechanism is i.e. main direction of studying.
The present inventor is found by experiment that, by bactericide compounded to propiconazoles different for the mechanism of action and octyl trichlamide, has substantially
Synergistic function, and medicament osmosis can be improved, extend the lasting period, not only significantly improve fruit tree, forest branch sick
The treatment of evil, protected effect, simultaneously by the treatment protection of tree body is added conditioning, reach cure trunk disease and prevent it from recurring
Purpose.
The present invention containing octyl trichlamide and the bactericidal composition of propiconazole, effective ingredient propiconazole and the mechanism of action of octyl trichlamide
Entirely different, compound and can act in sites many to pathogen, Synergistic, expand fungicidal spectrum, improve preventive effect, reduce Pesticide use
Amount, delays drug-fast generation, reduces resistance risk.
The present invention containing octyl trichlamide and the bactericidal composition of propiconazole, can provide with finished product preparation form, it is also possible to single dose
Form provides, and before using, directly mixing, is then watered mixing and is made into desired concn, smear, simultaneously after striking off branch position disease scar
Coordinate whole plant spraying using effect more preferably.
The present invention containing octyl trichlamide and the bactericidal composition of propiconazole, have the advantage that 1, there is synergistic function,
Improve prevention effect；2, fungicidal spectrum is expanded；3, two kinds of effective ingredient mechanisms of action are different, and mixture uses and delays pathogen Drug resistance
Generation；4, reduce formulation rate, reduce access times, reduce use cost.
Detailed description of the invention
Below in conjunction with embodiment, the present invention is further illustrated.
Instrument involved in following embodiment, reagent, material etc., unless otherwise noted, be in prior art existing
Conventional instrument, reagent, material etc., can be either commercially available by regular.Experimental technique involved in following embodiment, inspection
Survey methods etc., unless otherwise noted, are existing normal experiment method in prior art, detection method etc..
Experiment propiconazole preventive and therapeutic effect to disease compounding with octyl trichlamide studies (Toxicity Determination)
One, reagent agent: propiconazole, the former medicine of octyl trichlamide, and thiophanate-methyl, ambam, Tebuconazole.By the third ring
The former medicinal acetone solution of azoles, octyl trichlamide, and it is made into the mother solution of 10000 μ g/mL, the volume fraction with 0.2% adds emulsifying agent
Tween-80, preserves standby in refrigerator, is diluted to debita spissitudo with sterilized water during use at 4 DEG C.
Two, for examination pathogen: Valsa mali (Valsa mali), eyespot in apple limb bacterium
(Botryosphaeria dothidea), Ramulus Juglandis rot bacterium (Phomopsisjuglandina), Fructus Pruni pseudocerasi gummosis pathogenic bacteria
(Botryosphaeria dothidea), dothiorella gregaria bacterium (Botryosphaeria dothidea), blue berry branch-rot bacterium
(Neofusicoccumparvum)。
Three, assay method:
(1) Toxicity Determination: use mycelial growth rate method that propiconazole, octyl trichlamide and mixture preparation thereof are carried out virulence
Measure.
Single dose toxicity test method:
First reagent agent (including propiconazole, octyl trichlamide, thiophanate-methyl, ambam, Tebuconazole) is configured to 6 concentration
Gradient (propiconazole: 0.5,1.0,2.0,4.0,8.0,6 Concentraton gradient such as 16.0mg/kg；Octyl trichlamide: 1.0,2.0,4.0,
8.0,16.0,6 Concentraton gradient such as 32.0mg/kg；Thiophanate-methyl: 0.5,1.0,2.0,4.0,8.0,16.0mg/kg etc. 6
Concentraton gradient；Ambam: 3.0,6.0,12.0,24.0,48.0,6 Concentraton gradient such as 96.0mg/kg；0.5,1.0 Tebuconazole:,
2.0,4.0,8.0,6 Concentraton gradient such as 16.0mg/kg), by pathogen 26 DEG C of precultures 4d in PDA culture medium, use diameter
The card punch of 7mm is beaten on the same circumference of close colony edge and is taken bacterium cake, is inoculated into the culture medium containing different agents concentration
On flat board, every ware is a piece of, cultivates 4d, measure the colony growth diameter of each process by decussation method in being placed in 26 DEG C of calorstats,
With clear water for comparison, every concentration processes and is repeated 4 times.Measure the most linear increment of bacterium colony, determine that colony growth is pressed down by medicament
Rate processed.By the linear regression analysis between mycelial growth suppression probit and drug concentration logarithm value, obtain each medicament to bacterium
Concentration (EC in the effectively suppression of strain50Value).
Mixed agent joint toxicity measuring:
On the basis of single dose toxicity test, its EC will be pressed respectively for the propiconazole of mixture, octyl trichlamide50Value dosage is by volume
Ratio be respectively provided with 10:1,5:1,2:1,1:1,1:2,1:5,1:10,1:15,1:20,1:25,1:30,1:35,1:40,1:45,
1:50 totally 15 proportionings, by different ratio be configured to final mass concentration (referring to the gross mass of propiconazole, octyl trichlamide) be 0.25,
0.5,1.0,2.0,4.0, the pastille PDA culture medium of 6 series concentration of 8.0mg/kg, measure the medicament suppression to mycelial growth
Rate.Often process (the every concentration level of every bacterial strain) to be repeated 4 times.By between mycelial growth suppression probit and drug concentration logarithm value
Linear regression analysis, obtain Mixed Pharmacy to concentration EC in the effectively suppression of bacterial strain50Value and CTC value, with the PDA of not adding medicine
Culture medium is as comparison.
(2) data statistic analysis
Test data is carried out statistical analysis by Microsoft Excel 2013, DPS data processing work platform, calculates
Go out the EC of every kind of medicament50Value, 95% confidence limit.The abundant method of Sun Yun (1960) is utilized to calculate the co-toxicity coefficient of mixed agent, according to common poison
Coefficient magnitude evaluates the potentiation of mixed agent.
According to the below equation each medicament suppression ratio of calculating:
Developing restraint rate (%)=[(comparison antibacterial circle diameter-process antibacterial circle diameter)/(comparison antibacterial circle diameter-5mm
Punching diameter)] × 100；
Developing restraint rate (%)=[(comparison colony diameter-process colony diameter)/(comparison colony diameter-bacterium cake diameter)]
×100；
Toxicity index TI=(standard agent EC50/ reagent agent EC50)×100；
Mixed agent actual toxicity index ATI=(standard agent EC50/ mixture preparation EC50)×100；
(PA and PB is respectively mixed agent to the TI × PB of TI × PA+ single dose B of mixed agent theory toxicity index TTI=single dose A
The percentage composition of middle effective ingredient)；
Theoretical toxicity index TTI × 100 of the actual toxicity index ATI/ mixed agent of co-toxicity coefficient CTC=mixed agent；
Potentiation judges: CTC >=120, has potentiation；80 ＜ CTC ＜ 120, for summation action；CTC≤80, for
Antagonism.
(3) result and analysis: as shown in table 1～table 8.
The 15 kinds of medicaments of the table toxicity test result to Valsa mali
Table 2 propiconazole and the octyl trichlamide different proportion mixture toxicity test result to Valsa mali
From table 1～2, propiconazole, octyl trichlamide and mixture preparation thereof, Valsa mali is had and well suppresses to make
With, when wherein the proportioning of propiconazole and octyl trichlamide is between 1:1～1:15, to for examination pathogen co-toxicity coefficient all 120 with
On, show that both antibacterial have good synergistic function under this proportioning, especially proportioning is between 1:1～1:10
Potentiation is the most notable.
35 kinds of medicaments of table are to eyespot in apple limb bacterium, Fructus Pruni pseudocerasi gummosis pathogenic bacteria, the toxicity test result of dothiorella gregaria bacterium
Eyespot in apple limb bacterium, Fructus Pruni pseudocerasi gummosis pathogenic bacteria, willow are burst by table 4 propiconazole with octyl trichlamide different proportion mixture
The toxicity test result of infections pathogenic bacteria
From table 3～4, propiconazole, octyl trichlamide and mixture preparation thereof, to eyespot in apple limb bacterium, Fructus Pruni pseudocerasi bleeding disease
Bacterium, dothiorella gregaria bacterium are respectively provided with good inhibiting effect, and wherein the proportioning of propiconazole and octyl trichlamide is between 2:1～1:20
Time, to the co-toxicity coefficient for examination pathogen all more than 120, show that both antibacterial have under this proportioning the most collaborative
Potentiation, especially proportioning potentiation between 1:5～1:15 is the most notable.
The 55 kinds of medicaments of the table toxicity test result to Ramulus Juglandis rot bacterium
Table 6 propiconazole and the octyl trichlamide different proportion mixture toxicity test result to Ramulus Juglandis rot bacterium
From table 5～6, propiconazole, octyl trichlamide and mixture preparation thereof, Ramulus Juglandis rot bacterium is had and well suppresses to make
With, when wherein the proportioning of propiconazole and octyl trichlamide is between 2:1～1:30, to for examination pathogen co-toxicity coefficient all 120 with
On, show that both antibacterial have good synergistic function under this proportioning, especially proportioning is between 1:1～1:20
Potentiation is the most notable.
The 75 kinds of medicaments of the table toxicity test result to blue berry branch-rot bacterium
Table 8 propiconazole and the octyl trichlamide different proportion mixture toxicity test result to blue berry branch-rot bacterium
From table 7～8, propiconazole, octyl trichlamide and mixture preparation thereof, blue berry branch-rot bacterium is had and well suppresses to make
With, when wherein the proportioning of propiconazole and octyl trichlamide is between 1:1～1:25, to for examination pathogen co-toxicity coefficient all 120 with
On, show that both antibacterial have good synergistic function under this proportioning, especially proportioning is between 1:2～1:15
Potentiation is the most notable.
Embodiment 1 6% propiconazole octyl trichlamide wettable powder
Component composition is following (each component is by weight percentage):
Preparation method is: above-mentioned each active component, various auxiliary agent and filler are sufficiently mixed in proportion uniformly, mixture warp
Ultra-fine pulverizer disintegrating, prepares 6% propiconazole octyl trichlamide wettable powder.
Embodiment 2 20% propiconazole octyl trichlamide suspending agent
Component composition is following (each component is by weight percentage):
Preparation method is: above-mentioned each active component, various auxiliary agent and water are sufficiently mixed in proportion uniformly, puts into sand milling
Machine, is ground to particle diameter 5 μm, 20% propiconazole octyl trichlamide suspending agent.
Embodiment 3 11% propiconazole octyl trichlamide cream
Component composition is following (each component is by weight percentage):
Preparation method is: above-mentioned each active component, various auxiliary agent and water are sufficiently mixed in proportion, adds in mixing kettle,
The 11% propiconazole octyl trichlamide cream stirred.
Embodiment 4:20% propiconazole octyl trichlamide aqueous emulsion
Component composition is following (each component is by weight percentage):
Preparation method is: above-mentioned each active component, various auxiliary agent are sufficiently mixed in proportion, makes to be dissolved into all and oil phase,
Under high-speed stirred, oil phase is mixed with water, obtains 20% propiconazole octyl trichlamide aqueous emulsion.
Embodiment 5:7% propiconazole octyl trichlamide water dispersible granules
Component composition is following (each component is by weight percentage):
Preparation method is: by above-mentioned each active component, Negel formaldehyde condensation products, wetting agent, disintegrating agent, filler
It is sufficiently mixed in proportion, is crushed to particle diameter 5 μm through jet mill, obtains female powder, mother's powder is sufficiently mixed with sodium lignin sulfonate
Rear pelletize, dry, sieve, thus prepare 7% propiconazole octyl trichlamide water dispersible granules.
Embodiment 6:18% propiconazole octyl trichlamide microemulsion
Component composition is following (each component is by weight percentage):
Preparation method is: above-mentioned each active component, various auxiliary agent are sufficiently mixed in proportion, makes to be dissolved into all and oil phase,
Under high-speed stirred, oil phase is mixed with water, obtains 18% propiconazole octyl trichlamide microemulsion.
Application example 1: field control canker of apple fruit field control effectiveness test
Within 2014, it is carried out example 1 (6% propiconazole octyl trichlamide wettable powder) in Feicheng, Shandong Province and prevents and treats Herba Marsileae Quadrifoliae
Fruit tree putrefaction disease field control effectiveness test, verifies the prevention effect of this medicament, effective dose and the safety to apple tree.Test side
Method is with reference to " GB/T 17980.98-2004 pesticide field efficacy medicine test criterion (two) bactericidal agent for preventing and treating apple tree canker drug effect is tried
Test ".Test site is in Zhang An village, An Jiazhuan town, and test tree is 17 years tissue regeneration promoting Red Stars, spacing in the rows × line-spacing=3m × 4m, rich water quality management
Level is general, extensive management, and tree vigo(u)r is weak, and the trunk disease such as canker, ring spot occurs heavier.
Test medicine and dosage is: 6% propiconazole octyl trichlamide wettable powder 200 times, 400 times, 600 times；3% methyl
Thiophanate paste；2.12% copper humate water preparation；40% asomate wettable powder 50 times；Blank, only removes sick scar
Without chemicals treatment.Tree vigo(u)r scar position close, sick and the close sick scar of sick scar size is selected to be marked.Every community becomes tree in age extremely
Few 5 strains, the newest sick scar at least 8, it is repeated 4 times.
Test and carry out on March 12nd, 2014.Medication after scab cleaning, is to use to produce upper conventional to scrape method for the treatment of, the most first
With scraper, canker disease portion being shaved the most clear limit and exceed disease portion slough 0.5～1cm, sick scar otch requires to stand stubble, fusiformis, so
After again with hairbrush by liquid medicine painting disease portion and beyond otch 2～3cm, all moisten with coating position, medicinal liquid is the dirtiest for degree.
Blank only strikes off scab, clear good limit, but is not coated with medicament.
A scab recurrence is respectively investigated when December in 2014 early winter on the 3rd and the early spring on the 15th March in 2015.Record is multiple
Morbidity scar quantity.Simultaneously with vernier caliper measurement maximum healing width (mm) that records disease scar.And medication after scab is cleared up
Statistical is carried out respectively with direct drug injection.
Drug effect statistical analysis technique: calculate pharmacy control efficacy by following equation.
a.
b.
(note: in table 9～table 12, each extension rate, to the solid such as wettable powder, water dispersible granules as shown in table 9 for result
For dosage form, refer to quality multiple, for liquid dosage form, refer to volume multiple).
The pharmacodynamic results of apple tree canker prevented and treated by table 9 6% propiconazole octyl trichlamide wettable powder
Field apple tree canker therapeutic test result sees the above table 9.From table, 6% propiconazole octyl trichlamide wettability
The field control effect that each concentration of powder processes is best, and cure rate is more than 80.0%, wherein with 200 times of best results, significantly
It is better than other each conventional treatment, and wound healing is fast, smooth.
Application example 2: field apple tree Trunk canker therapeutic test
Within 2014, it is carried out example 2 (20% propiconazole octyl trichlamide suspending agent) in Feicheng, Shandong Province and prevents and treats apple tree
Trunk canker field control effectiveness test, verifies the prevention effect of this medicament, effective dose and the safety to apple tree.Experimental field
Point is at Wu villages and small towns Wu Cun, and test tree is 19 years raw golden marshall apples, and rich water quality management level is general, and tree vigo(u)r is weak, spacing in the rows × line-spacing=3
× 4m, branch disease tumor is more.
Design 5 tests to process: 20% propiconazole octyl trichlamide suspending agent 200 times, 400 times, 600 times；3% methyl sulfur bacterium
Spirit paste；430g/L tebuconazole suspension concentrates 200 times；Blank, only removes sick scar without chemicals treatment.Every 20 strain trees are one
Community, is repeated 4 times, and every community selects the position that tree vigo(u)r scar close, sick is close to be marked.
Test and carry out on November 30th, 2014, strike off on trunk and 2 years sick above branches after tumor, be uniformly coated with hairbrush
Smearing medicinal liquid, until trunk base portion, average every strain is coated with medicinal liquid about about 500 milliliters, after having smeared, entirely sets spraying.In coating
Before, the two strain trees in every community by all directions in every orientation, orientation select the raw branches of 5 3-4, paint demarcation the most respectively
The trunk having certain sick tumor of 60-100 square centimeter or branch section.
Before dispenser with each investigation on April 30 in 2015 once, investigate altogether twice.Investigate in each labelling area of each community
Sick tumor quantity, before coating, sick tumor number is as radix, the sick tumor rate of increase of statistics, calculates prevention effect.
Result is as shown in table 10.
Table 10 20% propiconazole octyl trichlamide suspending agent preventing and treating eyespot in apple limb test initial data statistical table
(2015)
20% propiconazole octyl trichlamide suspending agent preventing and treating eyespot in apple limb result of the test sees the above table 10.From table,
20% 200 times of field control effects of propiconazole octyl trichlamide suspending agent are best, and cure rate, 85.85%, is significantly better than its elsewhere
Reason, uses 20% propiconazole octyl trichlamide suspending agent on producing in the way of branch is smeared, and bactericidal effect is good, environmental pollution
Little, it is the applicable dosage form of preventing and treating eyespot in apple limb.
Application example 3: field cherry tree bleeding disease therapeutic test
Within 2014, it is carried out example 4 (20% propiconazole octyl trichlamide aqueous emulsion) in Tai'an, Shandong Province and prevents and treats cherry tree
Bleeding disease field control effectiveness test, verifies the prevention effect of this medicament, effective dose and the safety to cherry tree.
Test is carried out in large cherry planting base, the village, Xiyuan, Taishan District, and test tree is 16 years raw red lights, choose tree vigo(u)r suitable,
The plant that the state of an illness is close, control measures are consistent is as examination material.Design 5 tests to process: 20% propiconazole octyl trichlamide aqueous emulsion
200 times, 400 times, 600 times；430g/L tebuconazole suspension concentrates 200 times；3% thiophanate-methyl paste；5 Baume degrees lime sulfurs；
Blank, only removes colloid without chemicals treatment.Every 4 strain trees are a community, are repeated 4 times, random alignment.
Remove disease portion dead bark, breach and blob of viscose on April 25th, 2014 (before rainy season starts), indulge at sick cortex with scraper
Horizontal cut, then smears test medicine with scrub-brush, and scope exceeds disease portion 3-5cm.It is spaced and repastes once for 7 days.
Every community is coated with 20 gummosis scabs, often processes and amounts to 80.It is coated with latter 60 days to observe and cures (no longer gummosis) number and stream
Healing state (stopping gummosis, the most dead tissue is replaced by cambium) at glue, using cure rate as indicator-specific statistics prevention effect.
Result is as shown in table 11.
Table 11 cherry tree gummosis therapeutic test result
Field cherry tree bleeding disease therapeutic test the results are shown in Table 11.As seen from table, 20% propiconazole octyl trichlamide aqueous emulsion
200 times of field control effects are best, and cure rate, 87.50%, is significantly better than other each conventional treatment, and wound healing is fast,
Smooth.
Application example 4: field branch of Semen Juglandis rot therapeutic test
Example 5 (7% the third within 2013, it is carried out in Semen Juglandis base, Tai'an, Shandong Province Shandong Fruit-tree Inst. five orchard
Cyc bacterium aqueous amine dispersible granule) preventing and treating branch of Semen Juglandis rot field control effectiveness test, verify the prevention effect, effectively of this medicament
Dosage and the safety to walnut.
Test is carried out in Semen Juglandis base, Shandong Fruit-tree Inst. five orchard, and test tree is the fragrant tinkling of pieces of jade, chooses tree vigo(u)r suitable, sick
The plant that feelings are close, control measures are consistent is as examination material.Design 5 tests to process: 7% propiconazole octyl trichlamide water dispersible granules
1000 times, 1500 times, 2000 times；430g/L tebuconazole suspension concentrates 2500 times；70% thiophanate-methyl wettable powder 700 times；
Blank.Every 4 strain trees are a community, are repeated 4 times, community random alignment, and sign of listing.
Disease investigation and preventive effect calculate 15d and 40d after last 1 dispenser respectively, investigation, calculate strain disease branch rate and deadwood
Rate, calculates effect of chemical control simultaneously.
Starting the 1st dispenser in their early stage, power driven sprayer carries out Herb spraying treatment, each dispenser interval 10～
15d.After last dispenser and medicine thereof, 20d investigates sickness rate and the disease index of each process community, during investigation every strain tree eastern,
South, west, direction, 4, north totally 80 shoots (20, every direction), calculate Investigate incidence and disease index, use DMRT method statistics
Analyzing result of the test, whether investigation walnut is affected by institute's dispenser agent and is produced poisoning simultaneously, and the symptom type of poisoning
And extent of injury.
The field severity Scaling of Ramulus Juglandis rot divides 6 grades, specific as follows:
0 grade, Herb is anosis；1 grade, walnut branch scab is around the 50% of branch girth, and 10% is wilting with lower blade；3
Level, walnut branch scab is wilting around 51%～100%, 11%～30% blade of branch girth；5 grades, walnut branch
Scab cincture branch 1 week, 31%～50% blade is wilting, and branch is slightly withered；7 grades, walnut branch scab is around branch 1
In week, 51%～70% blade is wilting, fallen leaves, and branch moderate is withered；9 grades, branch of Semen Juglandis branch scab cincture branch 1 week, 70%
, fallen leaves wilting with blade, branch is withered.Disease index, preventive effect etc. are with reference to the method for Huang Guoyang, and data statistics utilizes DPS soft
Part completes.
a.
b.
The results are shown in Table 12.
Table 12 field branch of Semen Juglandis rot prevents and treats result
Field Ramulus Juglandis rot therapeutic test the results are shown in Table 12.7% propiconazole octyl trichlamide water dispersible granules 1000 times,
1500 times of field control effects are best, and cure rate, all more than 90.0%, is significantly better than other and respectively processes, and pacify walnut
Entirely.
Claims (10)
1. one kind contains octyl trichlamide and the bactericidal composition of propiconazole, it is characterised in that: effective ingredient is octyl trichlamide and propiconazole, third
Ring azoles is 2:1～1:30 with the weight ratio of octyl trichlamide.
It is the most according to claim 1 containing octyl trichlamide with the bactericidal composition of propiconazole, it is characterised in that: described containing octyl trichlamide
Be made up of the component of following weight portion with the bactericidal composition of propiconazole: propiconazole 1%～80%, octyl trichlamide 1%～
80%, surplus is to allow in Pesticide Science to use and acceptable adjuvant；Described Pesticide Science allows use and acceptable
Adjuvant is selected from solvent, penetrating agent, dispersant, diffusant, disintegrating agent, emulsifying agent, stabilizer, wetting agent, defoamer, antifreezing agent,
Or other contributes to the stable of effective ingredient drug effect and allowing of playing makes used additives.
It is the most according to claim 1 containing octyl trichlamide with the bactericidal composition of propiconazole, it is characterised in that: described Bactericidal composite
The dosage form of thing is wettable powder, suspending agent, cream, aqueous emulsion, water dispersible granules or microemulsion.
4. according to according to any one of claims 1 to 3 containing octyl trichlamide and the bactericidal composition of propiconazole, it is characterised in that:
The dosage form of described bactericidal composition is wettable powder, is made up of the component of following percetage by weight:
5. according to according to any one of claims 1 to 3 containing octyl trichlamide and the bactericidal composition of propiconazole, it is characterised in that:
The dosage form of described bactericidal composition is suspending agent, is made up of the component of following percetage by weight:
6. according to according to any one of claims 1 to 3 containing octyl trichlamide and the bactericidal composition of propiconazole, it is characterised in that:
The dosage form of described bactericidal composition is cream, is made up of the component of following percetage by weight:
7. according to according to any one of claims 1 to 3 containing octyl trichlamide and the bactericidal composition of propiconazole, it is characterised in that:
The dosage form of described bactericidal composition is aqueous emulsion, water dispersible granules or microemulsion,
When dosage form is aqueous emulsion, it is made up of the component of following percetage by weight:
When dosage form is water dispersible granules, it is made up of the component of following percetage by weight:
When dosage form is microemulsion, it is made up of the component of following percetage by weight:
8. the bactericidal composition containing octyl trichlamide and propiconazole according to any one of claim 1～7 is at preventing and treating fruit tree, forest branch
Application in dry disease, or as fruit tree, forest grafting, beta pruning sealing compound in application.
Application the most according to claim 8, it is characterised in that: described disease is selected from canker of apple fruit, Fructus Mali pumilae branch wheel stricture of vagina
Disease, dry rot of apple, Fructus Pruni pseudocerasi bleeding disease, peach gummosis, blue berry branch-rot, branch of poplar rot, dothiorella gregaria, Ramulus Juglandis are withered
Sick.
Application the most according to claim 9, it is characterised in that: when preventing and treating Valsa mali, propiconazole and octyl trichlamide
The weight ratio of the two is preferred with 1:1～15, and more preferably, 1:5 is optimal for 1:1～10；When preventing and treating eyespot in apple limb bacterium, propiconazole
Being preferred with 2:1～1:20 with the weight ratio of both octyl trichlamide, more preferably, 1:5 is optimal for 1:5～15；When preventing and treating Fructus Pruni pseudocerasi gummosis pathogenic bacteria,
Propiconazole is preferred with 2:1～1:20 with the weight ratio of both octyl trichlamide, and more preferably, 1:5 is optimal for 1:5～15；In preventing and treating willow ulcer
During pathogenic bacteria, propiconazole is preferred with 2:1～1:20 with the weight ratio of both octyl trichlamide, and more preferably, 1:5 is optimal for 1:5～15；At preventing and treating core
During Ramulus Persicae rot bacterium, propiconazole is preferred with 2:1～1:30 with the weight ratio of both octyl trichlamide, and more preferably, 1:5 is optimal for 1:1～20；
Prevent and treat blue berry branch-rot bacterium time, propiconazole is preferred with 1:1～25 with the weight ratio of both octyl trichlamide, 1:2～15 more preferably, 1:5
Most preferably.
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| CN201610598645.9A CN106172425B (en) | 2016-07-26 | 2016-07-26 | A kind of bactericidal composition and its application containing octyl trichlamide and propiconazole |
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Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN107258816A (en) * | 2017-07-20 | 2017-10-20 | 天津市瀚葳园林植物保护技术有限公司 | A kind of composition pesticide for being used to treat and prevent dothiorella gregaria |
| CN107950646A (en) * | 2017-12-06 | 2018-04-24 | 宁波市农业科学研究院 | A kind of peach method for storing and refreshing |
| WO2019091376A1 (en) * | 2017-11-07 | 2019-05-16 | 江苏东宝农化股份有限公司 | Antimicrobial composition containing triflumizole and octylamine as main active ingredients |
Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103039461A (en) * | 2012-12-17 | 2013-04-17 | 广东中迅农科股份有限公司 | Pesticide composition containing zinc bacteria amine and hexaconazole |
| CN103238611A (en) * | 2013-05-27 | 2013-08-14 | 雷军永 | Medicament for preventing and treating apple tree canker |
| CN104106575A (en) * | 2014-07-31 | 2014-10-22 | 安徽省农业科学院植物保护与农产品质量安全研究所 | Fungicidal composition containing octyl trichlamide and diniconazole |
| CN104770368A (en) * | 2015-04-16 | 2015-07-15 | 山东省果树研究所 | Bactericidal composition containing coumoxystrobin and xinjunan and application thereof |
-
2016
- 2016-07-26 CN CN201610598645.9A patent/CN106172425B/en active Active
Patent Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103039461A (en) * | 2012-12-17 | 2013-04-17 | 广东中迅农科股份有限公司 | Pesticide composition containing zinc bacteria amine and hexaconazole |
| CN103238611A (en) * | 2013-05-27 | 2013-08-14 | 雷军永 | Medicament for preventing and treating apple tree canker |
| CN104106575A (en) * | 2014-07-31 | 2014-10-22 | 安徽省农业科学院植物保护与农产品质量安全研究所 | Fungicidal composition containing octyl trichlamide and diniconazole |
| CN104770368A (en) * | 2015-04-16 | 2015-07-15 | 山东省果树研究所 | Bactericidal composition containing coumoxystrobin and xinjunan and application thereof |
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN107258816A (en) * | 2017-07-20 | 2017-10-20 | 天津市瀚葳园林植物保护技术有限公司 | A kind of composition pesticide for being used to treat and prevent dothiorella gregaria |
| WO2019091376A1 (en) * | 2017-11-07 | 2019-05-16 | 江苏东宝农化股份有限公司 | Antimicrobial composition containing triflumizole and octylamine as main active ingredients |
| CN107950646A (en) * | 2017-12-06 | 2018-04-24 | 宁波市农业科学研究院 | A kind of peach method for storing and refreshing |
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| Publication number | Publication date |
|---|---|
| CN106172425B (en) | 2018-05-11 |
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