CN106726681B - A kind of method that uses sericin protein to prepare facial mask - Google Patents

Abstract

The invention discloses a method for preparing a facial mask with sericin protein, which comprises preparing a sericin solution with a concentration of 2%-5%, adding 0.5%-3% agar powder into the sericin solution, heating and stirring until After being uniformly dissolved, pour it into a mask mold, dry to form a sericin mask, and soak it in a 50%-80% ethanol solution for 10h-15h. The present invention has low energy consumption and biological safety in the whole process. high, low price, simple and convenient operation, and no pollution to the environment. The sericin protein mask prepared by this invention has the biological characteristics of whitening, moisturizing, anti-aging and light and transparent physical properties. The sericin mask prepared by this invention Sericin protein mask is more flexible in use, and different parts of the mask can be used according to individual needs.

Description

A kind of method that uses sericin protein to prepare facial mask

technical field

The invention relates to a method for preparing facial mask with sericin, which belongs to the processing method of sericin.

Background technique

Sericin is a globular protein with a relative molecular mass of 14,000 to 314,000, composed of 18 amino acids, among which serine (Ser), aspartic acid (Asp) and glycine (Gly) are relatively high in content, and their relative masses reach 33.43 %, 16.71% and 13.49%. The secondary structure of sericin is mainly non-coiled, and contains some β-concepts, and almost no α-helical structure. In the amino acid composition of sericin, polar side chain amino acids account for 74.61%. These amino acids with longer side chains on the sericin chain and polar hydrophilic groups are on the surface of the polypeptide, which can make the water in the structure transfer to Combined with the stratum corneum of the skin, it can promote the skin's absorption of moisture. The reversible sericin gel can be obtained by placing the sericin dissolved in water under natural conditions. The temperature of lyogel to gel transformation is generally below 60°C, and the temperature of gel to lyogel transformation is 50-70°C. During the transition from lyogel to gel, there is an irreversible transformation of some random coils to the β conformation. The strength of the gel is directly proportional to the concentration of the gel. The physical and chemical properties of the film can be improved by mixing the sericin aqueous solution with other substances to form a mixed film.

Mask is a product that is applied or spread on the surface of human skin, and after a period of time, it is peeled off, scrubbed or retained, which can play a concentrated care or cleaning effect. The principle of the mask is to use the short time covered on the face to temporarily isolate the outside air and pollution, increase the temperature of the skin, expand the pores of the skin, promote the secretion and metabolism of sweat glands, increase the oxygen content of the skin, and help the skin to eliminate the skin. The products of cell metabolism and accumulated oily substances, the moisture in the mask penetrates into the stratum corneum of the epidermis, the skin becomes soft, and the skin is naturally bright and elastic. According to the material of facial mask, it can be divided into powder blending facial mask, kaolin facial mask, non-woven facial mask and silk facial mask. Since the silk mask can be peeled off directly after use, and there is no need to clean the face, it is favored by consumers.

The facial mask made of sericin by this method has good hygroscopicity, can play a role similar to the natural moisturizing factor (Natural moisturizing factor, NMF) in the stratum corneum of the skin, and prevent the skin from wrinkling. It also has the property of inhibiting the activity of tyrosinase, which can prevent the formation of melanin in the skin and whiten the skin. The tyrosine (Tyr), tryptophan (Trp), and phenylalanine (Phe) in sericin can effectively absorb ultraviolet rays, effectively prevent the damage of the sun's ultraviolet rays to the skin, and reduce the occurrence of pigmentation.

Contents of the invention

The present invention aims at the characteristics of sericin protein and the vacant field of the existing silk mask, and develops a method for preparing a sericin protein mask sheet with simple process, convenient handling and functions of whitening, moisturizing and anti-aging.

In order to achieve the above object, the concrete technical scheme of the present invention is as follows:

The invention discloses a method for preparing a face mask with sericin, and the specific preparation steps are as follows:

1) preparing a sericin solution with a concentration of 2%-5%;

2) Add 0.5%-3% agar powder to the sericin solution, heat and stir until it dissolves evenly, and inject it into the mask mold;

3) Dried to form a sericin protein mask, soaked in ethanol solution of 50%-80% concentration for 10h-15h; when the time was too short, the mask was not fully cured and would still dissolve in water; when the time was too long, the Time cost; when the concentration is too low, the product is incompletely solidified and easily dissolved in water; when the concentration is too high, the product is easy to lose water, resulting in brittleness and brittleness, and the integrity performance is reduced, which also causes waste of ethanol and increases costs.

4) After cleaning with deionized water, soak in 0.5%-3% silk protein solution for 1h-4h, then it can be used. When the time is too short, the silk protein content in the mask is not enough, and the moisturizing performance decreases; when the time is too long, the time cost is increased, and bacteria are easy to breed. When the concentration of fibroin solution is too low, the content of fibroin is not high, which will affect the use effect; when the concentration of fibroin is too high, the use efficiency will be reduced and the cost will be increased due to the limited adsorption amount of the mask.

As a further improvement, the sericin solution of the present invention is freshly prepared sericin solution or prepared by dissolving sericin powder. If freshly prepared sericin solution is used, the preparation method is as follows: 1:20-1 : The bath ratio of 40 extracts the sericin solution, and carries out dialysis purification; when the bath ratio is too small, the concentration of the sericin protein extracted is too low, resulting in waste of water, heat and time, and the economic benefit declines; when the bath ratio is too high , Incomplete sericin extraction causes waste.

As a further improvement, the sericin in the present invention is silkworm sericin or wild silkworm sericin.

As a further improvement, the mask mold of the present invention includes an integral mask and a split mask, and the split mask is any one of a forehead patch, an eye patch, a nose patch, a face patch, and a chin patch.

As a further improvement, the agar concentration of the present invention is 0.5%-3%. When the concentration is too low, the thickness of the product is too thin and the mechanical properties are poor; when the concentration is too high, the thickness of the product is too thick, the permeability decreases, and gelation is prone to occur during injection molding, making it difficult to form a complete and uniform mask.

As a further improvement, the silk fibroin solution soaked in the present invention is a sericin solution or a silk fibroin solution.

As a further improvement, the drying described in the present invention is natural air drying or machine drying.

Compared with the prior art, the present invention has the following prominent features:

(1) The present invention has the advantages of low energy consumption, high biological safety, low price, simple and convenient operation, and no pollution to the environment during the whole treatment process.

(2) The sericin facial mask prepared by the invention has biological properties of whitening, moisturizing and anti-aging and light, thin and transparent physical properties.

(3) The sericin facial mask prepared by the invention can achieve the target properties when used alone.

(4) The sericin facial mask prepared by this invention can be used in conjunction with silk essences with different components according to the different needs of individuals.

(5) The sericin facial mask prepared by the invention has greater advantages in absorbing and adsorbing the nutrient solution.

(6) The whole preparation process is completed in aqueous solution, the reaction conditions are mild, the pollution to the environment caused by the use of organic solvents is avoided, and the operation steps are simple.

(7) The sericin facial mask prepared by the invention is more flexible in use, and different parts of the facial mask can be selected for use according to different needs of individuals.

Detailed ways

The technical scheme of the present invention will be further described below by specific examples:

The present invention is mainly implemented through the following schemes:

Dissolve agar in a certain amount of sericin solution to a certain concentration, heat and stir continuously to make it evenly mixed. Take a certain amount of solution and pour it into the mask sticker mold to make a film.

The technical solution of the present invention will be further described in detail through specific examples below. The following examples are explanations of the present invention and the present invention is not limited to the following examples.

Example 1

Co-heat 10g of dried silkworm cocoons in 200ml, 300ml, and 400ml of deionized boiling water for 30 minutes, filter, take 150ml and add 3.0g of agar powder, heat to dissolve, and pour into 10 nasal patch molds while hot. After natural air-drying for 24 hours, treat with 50% alcohol for 10 hours; wash with deionized water, soak in 0.5% sericin solution, and take it out after 1 hour.

Example 2

Co-heat 10g of dried cocoons in 300ml of deionized boiling water for 30min, take 300ml of the solution obtained by dialysis and purification, and divide it into 6 parts on average, add 0.25g, 0.5g, 0.75g, 1.0g, 1.25g, 1.5g of agar powder respectively, and heat Dissolve and pour 6 full-size masks while hot. After natural air-drying for 24 hours, treat with 70% alcohol for 12 hours; wash with deionized water, soak in 3% sericin solution, and take it out after 2 hours.

Example 3

Dissolve 1.5g of sericin powder in 100mL of deionized water, add 0.5g of agar powder, heat to dissolve, and pour it into 5 chin patch molds while hot. After drying in an oven for 6 hours, treat with 75% alcohol for 15 hours; wash with deionized water, soak in 2% silk fibroin solution, and take it out after 4 hours.

Finally, it should also be noted that the above examples are only a few specific embodiments of the present invention. Obviously, the present invention is not limited to the above embodiments, and many variations are possible. All deformations that can be directly derived or associated by those skilled in the art from the content disclosed in the present invention should be considered as the protection scope of the present invention.

Claims (6)

1. a kind of method for preparing mask sheet with sericin, which is characterized in that specific preparation process is as follows:

1) compound concentration is the sericin solution of 2%-5%；

2) the agar powder of 0.5%-3% is added in sericin solution, after heating stirring to uniform dissolution, is injected into facial mask mould In tool；

3) drying forms sericin facial mask, impregnates 10h-15h in the ethanol solution of 50%-80% concentration；

4) after deionized water cleaning, 1h-4h is impregnated in the fibroin solutions of 0.5%-3%, that is, can be used；

The sericin solution manufacturing method has dissolution sericin powder and fresh extractor sericin solution, fresh to mention The method for taking sericin solution is to extract sericin solution according to the bath raio deionized water of 1:20-1:40, is dialysed Purification.

2. the method according to claim 1 for preparing mask sheet with sericin, which is characterized in that the sericin For silkworm sericin or wild silkworm sericin.

3. the method according to claim 1 for preparing mask sheet with sericin, which is characterized in that the facial mask mold Including complete formula mask sheet and partition type mask sheet.

4. the method according to claim 3 for preparing mask sheet with sericin, which is characterized in that the partition type face Film patch be lower jaw patch, nose patch, eye sticker, forehead paste in any one.

5. the method according to claim 1 for preparing mask sheet with sericin, which is characterized in that the drying means It is dried for natural air drying and machine.

6. the method according to claim 1 for preparing mask sheet with sericin, which is characterized in that the immersion silk Protein solution is sericin solution or silk fibroin protein solution.