CN107001260B - 3-氧基-3-(芳氨基)丙酸酯、其制备方法、以及其在制备吡咯烷酮中的用途 - Google Patents
3-氧基-3-(芳氨基)丙酸酯、其制备方法、以及其在制备吡咯烷酮中的用途 Download PDFInfo
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- CN107001260B CN107001260B CN201580065080.1A CN201580065080A CN107001260B CN 107001260 B CN107001260 B CN 107001260B CN 201580065080 A CN201580065080 A CN 201580065080A CN 107001260 B CN107001260 B CN 107001260B
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C69/00—Esters of carboxylic acids; Esters of carbonic or haloformic acids
- C07C69/02—Esters of acyclic saturated monocarboxylic acids having the carboxyl group bound to an acyclic carbon atom or to hydrogen
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/18—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
- C07D207/22—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D207/24—Oxygen or sulfur atoms
- C07D207/26—2-Pyrrolidones
- C07D207/263—2-Pyrrolidones with only hydrogen atoms or radicals containing only hydrogen and carbon atoms directly attached to other ring carbon atoms
- C07D207/27—2-Pyrrolidones with only hydrogen atoms or radicals containing only hydrogen and carbon atoms directly attached to other ring carbon atoms with substituted hydrocarbon radicals directly attached to the ring nitrogen atom
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
- C07B31/00—Reduction in general
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C233/00—Carboxylic acid amides
- C07C233/01—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
- C07C233/02—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having nitrogen atoms of carboxamide groups bound to hydrogen atoms or to carbon atoms of unsubstituted hydrocarbon radicals
- C07C233/04—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having nitrogen atoms of carboxamide groups bound to hydrogen atoms or to carbon atoms of unsubstituted hydrocarbon radicals with carbon atoms of carboxamide groups bound to acyclic carbon atoms of an acyclic saturated carbon skeleton
- C07C233/07—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having nitrogen atoms of carboxamide groups bound to hydrogen atoms or to carbon atoms of unsubstituted hydrocarbon radicals with carbon atoms of carboxamide groups bound to acyclic carbon atoms of an acyclic saturated carbon skeleton having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a six-membered aromatic ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C233/00—Carboxylic acid amides
- C07C233/01—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
- C07C233/12—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by halogen atoms or by nitro or nitroso groups
- C07C233/15—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by halogen atoms or by nitro or nitroso groups with the substituted hydrocarbon radical bound to the nitrogen atom of the carboxamide group by a carbon atom of a six-membered aromatic ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/18—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
- C07D207/22—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D207/24—Oxygen or sulfur atoms
- C07D207/26—2-Pyrrolidones
- C07D207/273—2-Pyrrolidones with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to other ring carbon atoms
- C07D207/277—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Plural Heterocyclic Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Pyrrole Compounds (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201462088971P | 2014-12-08 | 2014-12-08 | |
| US62/088,971 | 2014-12-08 | ||
| PCT/US2015/063101 WO2016094117A1 (en) | 2014-12-08 | 2015-12-01 | 3-oxo-3-(arylamino)propanoates, a process for their preparation, and their use in preparing pyrrolidinones |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN107001260A CN107001260A (zh) | 2017-08-01 |
| CN107001260B true CN107001260B (zh) | 2020-11-10 |
Family
ID=54782892
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201580065080.1A Active CN107001260B (zh) | 2014-12-08 | 2015-12-01 | 3-氧基-3-(芳氨基)丙酸酯、其制备方法、以及其在制备吡咯烷酮中的用途 |
Country Status (17)
| Country | Link |
|---|---|
| US (1) | US10227286B2 (2) |
| EP (1) | EP3230264B1 (2) |
| JP (1) | JP6611816B2 (2) |
| KR (1) | KR102542215B1 (2) |
| CN (1) | CN107001260B (2) |
| AR (1) | AR102939A1 (2) |
| AU (1) | AU2015361018B2 (2) |
| BR (1) | BR112017009701B1 (2) |
| ES (1) | ES2759267T3 (2) |
| HU (1) | HUE047582T2 (2) |
| IL (1) | IL252637A (2) |
| MX (1) | MX382656B (2) |
| PL (1) | PL3230264T3 (2) |
| RU (1) | RU2712831C2 (2) |
| SG (1) | SG11201702924WA (2) |
| TW (1) | TWI694982B (2) |
| WO (1) | WO2016094117A1 (2) |
Families Citing this family (21)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US11589583B2 (en) | 2013-12-03 | 2023-02-28 | Fmc Corporation | Pyrrolidinones herbicides |
| CA2931961C (en) | 2013-12-03 | 2023-10-31 | Andrew Duncan Satterfield | Pyrrolidinones as herbicides |
| SG11201610720VA (en) | 2014-07-02 | 2017-01-27 | Du Pont | Piperidinone herbicides |
| EP3280709B1 (en) | 2015-04-10 | 2021-05-26 | FMC Corporation | Substituted cyclic amides as herbicides |
| BR112017020094B1 (pt) | 2015-04-27 | 2022-01-11 | Fmc Corporation | Composto, composições herbicidas, mistura de herbicida e método para controlar o crescimento de vegetação indesejada |
| JP7000160B2 (ja) | 2015-05-12 | 2022-01-19 | エフ エム シー コーポレーション | 除草剤としてのアリール置換二環式化合物 |
| JP6869192B2 (ja) | 2015-05-29 | 2021-05-12 | エフ エム シー コーポレーションＦｍｃ Ｃｏｒｐｏｒａｔｉｏｎ | 除草剤としての置換環状アミド |
| CN107709310B (zh) * | 2015-06-02 | 2021-09-24 | Fmc公司 | 取代的环酰胺及其作为除草剂的用途 |
| JP6937290B2 (ja) | 2015-07-31 | 2021-09-22 | エフ エム シー コーポレーションＦｍｃ Ｃｏｒｐｏｒａｔｉｏｎ | 除草剤として有用な環状ｎ−カルボキサミド化合物 |
| GB201617050D0 (en) | 2016-10-07 | 2016-11-23 | Syngenta Participations Ag | Herbicidal mixtures |
| RU2019122791A (ru) | 2016-12-21 | 2021-01-25 | Фмк Корпорейшн | Гербициды на основе нитрона |
| CN110740646B (zh) | 2017-03-21 | 2022-05-10 | Fmc公司 | 除草剂混合物、组合物和方法 |
| MX2019010969A (es) | 2017-03-21 | 2019-12-02 | Fmc Corp | Pirrolidinonas y proceso para prepararlas. |
| WO2018177837A1 (de) | 2017-03-30 | 2018-10-04 | Bayer Aktiengesellschaft | 4-cyclopentyl- und 4-cyclopropyl-2-oxopyrrolidin-3-carboxami d-derivate und verwandte verbindungen als herbizide pflanzenschutzmittel |
| WO2018177836A1 (de) | 2017-03-30 | 2018-10-04 | Bayer Aktiengesellschaft | N-cyclopropyl-2-oxopyrrolidin-3-carboxamid-derivate und verwandte verbindungen als herbizide pflanzenschutzmittel |
| AR111839A1 (es) | 2017-05-30 | 2019-08-21 | Fmc Corp | Lactamas 3-sustituidas herbicidas |
| AR111967A1 (es) | 2017-05-30 | 2019-09-04 | Fmc Corp | Amidas herbicidas |
| WO2019025156A1 (de) | 2017-08-03 | 2019-02-07 | Bayer Aktiengesellschaft | Substituierte pyrrolidinone sowie deren salze und ihre verwendung als herbizide wirkstoffe |
| GB201819747D0 (en) | 2018-12-04 | 2019-01-16 | Syngenta Participations Ag | Herbicidal compositions |
| CN113423272A (zh) | 2019-02-15 | 2021-09-21 | 先正达农作物保护股份公司 | 除草组合物 |
| IL322597A (en) | 2021-12-15 | 2025-10-01 | Adama Agan Ltd | Compounds useful for the preparation of various agrochemicals and their markers |
Citations (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4874422A (en) * | 1988-12-27 | 1989-10-17 | Ici Americas Inc. | 1-Phenyl-3-carboxyamidopyrrolidones and their use as herbicides |
| WO2004037787A1 (de) * | 2002-10-18 | 2004-05-06 | Basf Aktiengesellschaft | 1-phenylpyrrolidin-2-on-3-carboxamide |
| CN101747252A (zh) * | 2009-12-28 | 2010-06-23 | 嘉兴宜博生物医药科技有限公司 | R构诺普利兰的合成方法 |
| CN102300845A (zh) * | 2009-02-23 | 2011-12-28 | 霍夫曼-拉罗奇有限公司 | 用于治疗癌症的新型邻氨基酰胺类 |
| WO2015084796A1 (en) * | 2013-12-03 | 2015-06-11 | E. I. Du Pont De Nemours And Company | Pyrrolidinones as herbicides |
| CN107709310A (zh) * | 2015-06-02 | 2018-02-16 | 杜邦公司 | 取代的环酰胺及其作为除草剂的用途 |
Family Cites Families (36)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE1262277B (de) | 1962-12-05 | 1968-03-07 | Basf Ag | Verfahren zur Herstellung von Pyrrolidonen |
| US3741989A (en) | 1970-10-27 | 1973-06-26 | Abbott Lab | Lactonic acetals |
| JPS5356288A (en) | 1976-10-30 | 1978-05-22 | Matsushita Electric Works Ltd | Preparation of phenolic resin |
| JPS5488114A (en) | 1977-12-26 | 1979-07-13 | Fuji Photo Film Co Ltd | Manufacturing device for photograph seal |
| US4594094A (en) | 1983-04-04 | 1986-06-10 | Shell Oil Company | Oxacycloalkane-alpha-(thio)carboxylic acid derivatives and use as plant growth regulators and herbicides |
| JP3487669B2 (ja) | 1995-03-28 | 2004-01-19 | 積水化学工業株式会社 | 不飽和ポリエステル樹脂組成物 |
| WO2000009481A1 (en) | 1998-08-11 | 2000-02-24 | Takeda Chemical Industries, Ltd. | Cyclic amide compounds, process for producing the same, intermediates thereof and herbicides |
| AU2002340971B2 (en) | 2001-10-08 | 2007-04-26 | Ucb | Use of 2-oxo-1-pyrrolidine derivatives for the treatment of dyskinesia and movement disorders |
| AU2003268184A1 (en) | 2002-08-23 | 2004-03-11 | Chiron Corporation | Pyrrole based inhibitors of glycogen synthase kinase 3 |
| AU2003277721A1 (en) | 2002-11-15 | 2004-06-15 | In Kwon Chung | Beta-nitrostyrene compound and telomerase inhibitor having an anticancer activity |
| US7205318B2 (en) | 2003-03-18 | 2007-04-17 | Bristol-Myers Squibb Company | Lactam-containing cyclic diamines and derivatives as a factor Xa inhibitors |
| MX2007008974A (es) | 2005-01-28 | 2007-09-18 | Irm Llc | Sintesis de aril-pirrolidonas. |
| US20070123508A1 (en) | 2005-05-27 | 2007-05-31 | Roger Olsson | PAR2-modulating compounds and their use |
| WO2007066828A1 (ja) | 2005-12-09 | 2007-06-14 | Sumitomo Chemical Company, Limited | 光学活性な４－アミノ－３－置換フェニルブタン酸の製造方法 |
| ES2304220B1 (es) | 2007-03-02 | 2009-09-11 | Universidad De Zaragoza | Composicion para el tratamiento de enfermedades infecciosas. |
| EP2065380A1 (en) | 2007-08-22 | 2009-06-03 | F.Hoffmann-La Roche Ag | Pyridoneamide derivatives as focal adhesion kinase (FAK) inhibitors and their use for the treatment of cancer |
| CN101412711A (zh) | 2007-10-15 | 2009-04-22 | 上海恒瑞医药有限公司 | 氨基甲酸酯类衍生物及其在医药上的应用 |
| JP5549592B2 (ja) | 2008-09-02 | 2014-07-16 | 日産化学工業株式会社 | オルト置換ハロアルキルスルホンアニリド誘導体及び除草剤 |
| WO2010053165A1 (ja) | 2008-11-04 | 2010-05-14 | 帝人ファーマ株式会社 | ビタミンｄ３ラクタム誘導体 |
| LT2603513T (lt) | 2010-08-10 | 2020-05-25 | Takeda Pharmaceutical Company Limited | Heterociklinis junginys ir jo panaudojimas kaip ampa receptoriaus teigiamo alosterinio moduliatoriaus |
| WO2012030685A2 (en) | 2010-09-01 | 2012-03-08 | Schering Corporation | Indazole derivatives useful as erk inhibitors |
| AU2012256237B2 (en) | 2011-05-13 | 2017-01-05 | Array Biopharma Inc. | Pyrrolidinyl urea and pyrrolidinyl thiourea compounds as TrkA kinase inhibitors |
| CN102531918B (zh) | 2012-01-18 | 2013-10-02 | 安阳工学院 | 一种对映纯对称反式二烷基环己胺的合成方法 |
| KR20130142477A (ko) | 2012-06-19 | 2013-12-30 | 순천향대학교 산학협력단 | 키랄 나이트로사이클로프로판 유도체의 제조방법 |
| US20160137639A1 (en) | 2012-10-26 | 2016-05-19 | Japan Tobacco Inc. | Triazole-isoxazole compound and medical use thereof |
| GB201321743D0 (en) | 2013-12-09 | 2014-01-22 | Ucb Pharma Sa | Therapeutic agents |
| RU2555370C1 (ru) | 2014-02-12 | 2015-07-10 | Федеральное государственное бюджетное образовательное учреждение высшего профессионального образования "Самарский государственный технический университет" | Способ энантиоселективного синтеза диэтил[3-метил-(1s)-(нитрометил)бутил]малоната формулы i |
| SG11201610720VA (en) | 2014-07-02 | 2017-01-27 | Du Pont | Piperidinone herbicides |
| EP3280709B1 (en) | 2015-04-10 | 2021-05-26 | FMC Corporation | Substituted cyclic amides as herbicides |
| BR112017020094B1 (pt) | 2015-04-27 | 2022-01-11 | Fmc Corporation | Composto, composições herbicidas, mistura de herbicida e método para controlar o crescimento de vegetação indesejada |
| JP7000160B2 (ja) | 2015-05-12 | 2022-01-19 | エフ エム シー コーポレーション | 除草剤としてのアリール置換二環式化合物 |
| JP6869192B2 (ja) | 2015-05-29 | 2021-05-12 | エフ エム シー コーポレーションＦｍｃ Ｃｏｒｐｏｒａｔｉｏｎ | 除草剤としての置換環状アミド |
| JP6937290B2 (ja) | 2015-07-31 | 2021-09-22 | エフ エム シー コーポレーションＦｍｃ Ｃｏｒｐｏｒａｔｉｏｎ | 除草剤として有用な環状ｎ−カルボキサミド化合物 |
| RU2019122791A (ru) | 2016-12-21 | 2021-01-25 | Фмк Корпорейшн | Гербициды на основе нитрона |
| MX2019010969A (es) | 2017-03-21 | 2019-12-02 | Fmc Corp | Pirrolidinonas y proceso para prepararlas. |
| CN110740646B (zh) | 2017-03-21 | 2022-05-10 | Fmc公司 | 除草剂混合物、组合物和方法 |
-
2015
- 2015-12-01 CN CN201580065080.1A patent/CN107001260B/zh active Active
- 2015-12-01 RU RU2017123114A patent/RU2712831C2/ru active
- 2015-12-01 ES ES15805092T patent/ES2759267T3/es active Active
- 2015-12-01 AU AU2015361018A patent/AU2015361018B2/en active Active
- 2015-12-01 WO PCT/US2015/063101 patent/WO2016094117A1/en not_active Ceased
- 2015-12-01 KR KR1020177018406A patent/KR102542215B1/ko active Active
- 2015-12-01 JP JP2017548361A patent/JP6611816B2/ja active Active
- 2015-12-01 PL PL15805092T patent/PL3230264T3/pl unknown
- 2015-12-01 MX MX2017007087A patent/MX382656B/es unknown
- 2015-12-01 BR BR112017009701-0A patent/BR112017009701B1/pt active IP Right Grant
- 2015-12-01 US US15/533,448 patent/US10227286B2/en active Active
- 2015-12-01 HU HUE15805092A patent/HUE047582T2/hu unknown
- 2015-12-01 SG SG11201702924WA patent/SG11201702924WA/en unknown
- 2015-12-01 EP EP15805092.2A patent/EP3230264B1/en active Active
- 2015-12-04 TW TW104140692A patent/TWI694982B/zh active
- 2015-12-04 AR ARP150103996A patent/AR102939A1/es active IP Right Grant
-
2017
- 2017-06-04 IL IL252637A patent/IL252637A/en active IP Right Grant
Patent Citations (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4874422A (en) * | 1988-12-27 | 1989-10-17 | Ici Americas Inc. | 1-Phenyl-3-carboxyamidopyrrolidones and their use as herbicides |
| WO2004037787A1 (de) * | 2002-10-18 | 2004-05-06 | Basf Aktiengesellschaft | 1-phenylpyrrolidin-2-on-3-carboxamide |
| CN102300845A (zh) * | 2009-02-23 | 2011-12-28 | 霍夫曼-拉罗奇有限公司 | 用于治疗癌症的新型邻氨基酰胺类 |
| CN101747252A (zh) * | 2009-12-28 | 2010-06-23 | 嘉兴宜博生物医药科技有限公司 | R构诺普利兰的合成方法 |
| WO2015084796A1 (en) * | 2013-12-03 | 2015-06-11 | E. I. Du Pont De Nemours And Company | Pyrrolidinones as herbicides |
| CN106414403A (zh) * | 2013-12-03 | 2017-02-15 | 纳幕尔杜邦公司 | 吡咯烷酮除草剂 |
| CN107709310A (zh) * | 2015-06-02 | 2018-02-16 | 杜邦公司 | 取代的环酰胺及其作为除草剂的用途 |
Non-Patent Citations (2)
| Title |
|---|
| Chiral 1,1’-Bi(tetrahydroisoquinoline)-Type Diamines as Efficient Ligands for Nickel-Catalysed Enantioselective Michael Addition to Nitroalkenes;Kristina Wilckens，等;《Eur. J. Org. Chem.》;20110808;第2011卷;第5441-5446页 * |
| Scope and Mechanism of Enantioselective Michael Additions of 1,3-Dicarbonyl Compounds to Nitroalkenes Catalyzed by Nickel(II)-Diamine Complexes;David A. Evans，等;《J. AM. CHEM. SOC.》;20070824;第129卷;第11583-11592页 * |
Also Published As
| Publication number | Publication date |
|---|---|
| IL252637A (en) | 2017-11-30 |
| WO2016094117A1 (en) | 2016-06-16 |
| CN107001260A (zh) | 2017-08-01 |
| MX382656B (es) | 2025-03-13 |
| SG11201702924WA (en) | 2017-05-30 |
| US10227286B2 (en) | 2019-03-12 |
| ES2759267T3 (es) | 2020-05-08 |
| KR20170090491A (ko) | 2017-08-07 |
| JP2017538785A (ja) | 2017-12-28 |
| AU2015361018A1 (en) | 2017-04-27 |
| EP3230264A1 (en) | 2017-10-18 |
| RU2712831C2 (ru) | 2020-02-03 |
| JP6611816B2 (ja) | 2019-11-27 |
| HUE047582T2 (hu) | 2020-05-28 |
| MX2017007087A (es) | 2017-09-05 |
| BR112017009701B1 (pt) | 2021-09-08 |
| AU2015361018B2 (en) | 2020-01-16 |
| US20180057442A1 (en) | 2018-03-01 |
| BR112017009701A2 (pt) | 2018-02-20 |
| EP3230264B1 (en) | 2019-09-11 |
| IL252637A0 (en) | 2017-07-31 |
| TWI694982B (zh) | 2020-06-01 |
| AR102939A1 (es) | 2017-04-05 |
| RU2017123114A (ru) | 2019-01-11 |
| KR102542215B1 (ko) | 2023-06-12 |
| TW201632497A (zh) | 2016-09-16 |
| PL3230264T3 (pl) | 2020-03-31 |
| RU2017123114A3 (2) | 2019-07-17 |
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