CN109072294A - 用于双重测序的改良衔接子、方法和组合物 - Google Patents

用于双重测序的改良衔接子、方法和组合物 Download PDF

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Publication number
CN109072294A
CN109072294A CN201680080120.4A CN201680080120A CN109072294A CN 109072294 A CN109072294 A CN 109072294A CN 201680080120 A CN201680080120 A CN 201680080120A CN 109072294 A CN109072294 A CN 109072294A
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nucleotide sequence
linking
nucleic acid
pair
sequence
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L·A·洛布
M·W·施密特
J·J·索尔克
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Twinstland Biosciences Co Ltd
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Twinstland Biosciences Co Ltd
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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6869—Methods for sequencing
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6844—Nucleic acid amplification reactions
    • C12Q1/6853—Nucleic acid amplification reactions using modified primers or templates
    • C12Q1/6855—Ligating adaptors

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  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Health & Medical Sciences (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • Immunology (AREA)
  • Biotechnology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Analytical Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
CN201680080120.4A 2015-12-08 2016-12-08 用于双重测序的改良衔接子、方法和组合物 Pending CN109072294A (zh)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201562264822P 2015-12-08 2015-12-08
US62/264,822 2015-12-08
US201662281917P 2016-01-22 2016-01-22
US62/281,917 2016-01-22
PCT/US2016/065605 WO2017100441A1 (en) 2015-12-08 2016-12-08 Improved adapters, methods, and compositions for duplex sequencing

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CN109072294A true CN109072294A (zh) 2018-12-21

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US (3) US11332784B2 (2)
EP (2) EP4043584A1 (2)
JP (3) JP6975507B2 (2)
CN (1) CN109072294A (2)
AU (1) AU2016366231B2 (2)
CA (1) CA3006792A1 (2)
ES (1) ES2911421T3 (2)
IL (1) IL259788B2 (2)
PL (1) PL3387152T3 (2)
PT (1) PT3387152T (2)
WO (1) WO2017100441A1 (2)

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