CN110187089B - 快速测量小容量样本中有形血液成分的沉降率 - Google Patents

快速测量小容量样本中有形血液成分的沉降率 Download PDF

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Publication number
CN110187089B
CN110187089B CN201910463083.0A CN201910463083A CN110187089B CN 110187089 B CN110187089 B CN 110187089B CN 201910463083 A CN201910463083 A CN 201910463083A CN 110187089 B CN110187089 B CN 110187089B
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hematocrit
blood
interface
centrifugation
sedimentation
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CN110187089A (zh
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M·戴耶尔
S·阿内卡尔
E·A·霍姆斯
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Theranos Inc
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Theranos Inc
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    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/04—Investigating sedimentation of particle suspensions
    • G01N15/042—Investigating sedimentation of particle suspensions by centrifuging and investigating centrifugates
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/04—Investigating sedimentation of particle suspensions
    • G01N15/05—Investigating sedimentation of particle suspensions in blood
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D21/00—Separation of suspended solid particles from liquids by sedimentation
    • B01D21/30—Control equipment
    • B01D21/32—Density control of clear liquid or sediment, e.g. optical control ; Control of physical properties
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/483—Physical analysis of biological material
    • G01N33/487—Physical analysis of biological material of liquid biological material
    • G01N33/49—Blood
    • G01N33/491—Blood by separating the blood components
    • G—PHYSICS
    • G06—COMPUTING OR CALCULATING; COUNTING
    • G06V—IMAGE OR VIDEO RECOGNITION OR UNDERSTANDING
    • G06V10/00—Arrangements for image or video recognition or understanding
    • G06V10/10—Image acquisition
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/01—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials specially adapted for biological cells, e.g. blood cells
    • G01N2015/011—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials specially adapted for biological cells, e.g. blood cells with lysing, e.g. of erythrocytes
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/01—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials specially adapted for biological cells, e.g. blood cells
    • G01N2015/012—Red blood cells
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/04—Investigating sedimentation of particle suspensions
    • G01N15/042—Investigating sedimentation of particle suspensions by centrifuging and investigating centrifugates
    • G01N2015/045—Investigating sedimentation of particle suspensions by centrifuging and investigating centrifugates by optical analysis
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/04—Investigating sedimentation of particle suspensions
    • G01N15/05—Investigating sedimentation of particle suspensions in blood
    • G01N2015/055—Investigating sedimentation of particle suspensions in blood for hematocrite determination

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Physics & Mathematics (AREA)
  • General Physics & Mathematics (AREA)
  • Hematology (AREA)
  • Biomedical Technology (AREA)
  • Pathology (AREA)
  • Immunology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Analytical Chemistry (AREA)
  • Dispersion Chemistry (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Urology & Nephrology (AREA)
  • Ecology (AREA)
  • Food Science & Technology (AREA)
  • Multimedia (AREA)
  • Theoretical Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Centrifugal Separators (AREA)
  • Investigating Or Analysing Materials By Optical Means (AREA)
CN201910463083.0A 2012-07-18 2013-07-18 快速测量小容量样本中有形血液成分的沉降率 Active CN110187089B (zh)

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US201261673037P 2012-07-18 2012-07-18
US61/673,037 2012-07-18
CN201380048272.2A CN104641230B (zh) 2012-07-18 2013-07-18 快速测量小容量样本中有形血液成分的沉降率

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US (6) US9347867B2 (2)
EP (1) EP2875351B1 (2)
JP (4) JP6336697B2 (2)
KR (1) KR20150036494A (2)
CN (2) CN110187089B (2)
AU (1) AU2013292378A1 (2)
BR (1) BR112015001239A2 (2)
CA (1) CA2878872A1 (2)
IL (1) IL236767A (2)
IN (1) IN2014DN11202A (2)
MX (1) MX372784B (2)
SG (2) SG10201605479QA (2)
WO (1) WO2014015177A1 (2)

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US8984932B2 (en) 2012-07-18 2015-03-24 Theranos, Inc. Rapid measurement of formed blood component sedimentation rate from small sample volumes
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CN106573256B (zh) 2014-07-30 2019-06-14 豪夫迈·罗氏有限公司 用于处理颗粒的自动化系统
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JP6327751B2 (ja) * 2015-10-06 2018-05-23 株式会社セルピック 自動血液分離装置
SG11201804776SA (en) * 2015-12-08 2018-07-30 Biomatrica Inc Reduction of erythrocyte sedimentation rate
WO2020170772A1 (ja) * 2019-02-21 2020-08-27 株式会社シンキー 遠心機において使用される検出器及び検出システム
SE545603C2 (en) * 2019-08-22 2023-11-07 Grimaldi Dev Ab Separating particles through centrifugal sedimentation
CN111712703B (zh) * 2019-11-18 2024-04-12 深圳迈瑞生物医疗电子股份有限公司 样本分析仪及样本分析方法
CN112033868B (zh) * 2020-09-01 2025-01-17 湖南伊鸿健康科技有限公司 一种加速细胞沉淀的方法、金属板及显微镜
CN111912753A (zh) * 2020-09-01 2020-11-10 湖南伊鸿健康科技有限公司 一种加速细胞沉淀的方法及装置
CN112034192B (zh) * 2020-09-07 2021-04-13 北京大学第三医院（北京大学第三临床医学院） 一种血沉校正方法
CN112766148A (zh) * 2021-01-18 2021-05-07 河南大学 一种受人类扰动冲积地层沉积韵律的识别方法及系统
TWI774220B (zh) * 2021-01-29 2022-08-11 國泰醫療財團法人國泰綜合醫院 紅血球沈降速率量測方法、血液檢測載體與量測套組
IT202100028064A1 (it) * 2021-11-04 2023-05-04 Arcangelo Ventura Dispositivo per la misura automatica della velocita' di sedimentazione e del volume del fango.
CN119173763A (zh) * 2022-05-10 2024-12-20 雷迪奥米特医学公司 基于全血样品中分析物的量的测量确定血浆中分析物的量
KR102791324B1 (ko) * 2023-03-22 2025-04-08 부산대학교 산학협력단 딥러닝을 이용한 적혈구 침강 속도 진단 시간 단축 방법 및 이를 위한 시스템
WO2025144706A1 (en) * 2023-12-28 2025-07-03 Idexx Laboratories, Inc. Determination of components in samples
CN119985470B (zh) * 2025-01-14 2025-09-19 中国人民解放军总医院第八医学中心 基于图像检测的血液分离血浆样本的层析效果评估方法

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US20190170630A1 (en) 2019-06-06
HK1210833A1 (en) 2016-05-06
EP2875351B1 (en) 2022-11-09
US10222310B2 (en) 2019-03-05
JP2018021936A (ja) 2018-02-08
SG10201605479QA (en) 2016-08-30
CA2878872A1 (en) 2014-01-23
WO2014015177A1 (en) 2014-01-23
MX2015000807A (es) 2015-05-07
KR20150036494A (ko) 2015-04-07
US20190226967A1 (en) 2019-07-25
US20140020457A1 (en) 2014-01-23
AU2013292378A1 (en) 2015-01-29
JP6336697B2 (ja) 2018-06-06
CN110187089A (zh) 2019-08-30
CN104641230B (zh) 2019-06-28
BR112015001239A2 (pt) 2017-07-04
JP2020012852A (ja) 2020-01-23
CN104641230A (zh) 2015-05-20
EP2875351A1 (en) 2015-05-27
EP2875351A4 (en) 2016-06-15
US20150198515A1 (en) 2015-07-16
JP2015528910A (ja) 2015-10-01
IN2014DN11202A (2) 2015-10-02
US20210140866A1 (en) 2021-05-13
IL236767A (en) 2017-06-29
US9347867B2 (en) 2016-05-24
US10018549B2 (en) 2018-07-10
JP2022009402A (ja) 2022-01-14
SG11201500349YA (en) 2015-02-27
US10788409B2 (en) 2020-09-29
US11320355B2 (en) 2022-05-03
US20160341650A1 (en) 2016-11-24
MX372784B (es) 2020-07-01

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