CN1104432C - 吡咯并三嗪和嘧啶化合物 - Google Patents

吡咯并三嗪和嘧啶化合物 Download PDF

Info

Publication number: CN1104432C
Authority: CN; China
Prior art keywords: ome; nhch; compound; formula; alkyl
Prior art date: 1996-07-24
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Expired - Lifetime

Application number

CN97196525A

Other languages

English (en)

Chinese (zh)

Other versions

CN1225637A (zh

Inventor

A·G·阿范尼蒂斯

R·J·乔尔瓦特

Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

Bristol Myers Squibb Pharma Co

Original Assignee

DuPont Merck Pharmaceutical Co

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1996-07-24

Filing date

1997-07-23

Publication date

2003-04-02

1997-07-23 Application filed by DuPont Merck Pharmaceutical Co filed Critical DuPont Merck Pharmaceutical Co

1997-07-23 Priority claimed from US08/899,242 external-priority patent/US6124289A/en

1999-08-11 Publication of CN1225637A publication Critical patent/CN1225637A/zh

2003-04-02 Application granted granted Critical

2003-04-02 Publication of CN1104432C publication Critical patent/CN1104432C/zh

2017-07-23 Anticipated expiration legal-status Critical

Status Expired - Lifetime legal-status Critical Current

Links

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Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)
Plural Heterocyclic Compounds (AREA)
Polymers With Sulfur, Phosphorus Or Metals In The Main Chain (AREA)
Macromolecular Compounds Obtained By Forming Nitrogen-Containing Linkages In General (AREA)
Agricultural Chemicals And Associated Chemicals (AREA)
Detergent Compositions (AREA)
Coloring (AREA)

CN97196525A 1996-07-24 1997-07-23 吡咯并三嗪和嘧啶化合物 Expired - Lifetime CN1104432C (zh)

Applications Claiming Priority (6)

Application Number	Priority Date	Filing Date	Title
US2329096P	1996-07-24	1996-07-24
US68604796A	1996-07-24	1996-07-24
US60/023,290		1996-07-24
US08/686,047		1996-07-24
US08/899,242		1997-07-23
US08/899,242 US6124289A (en)	1996-07-24	1997-07-23	Azolo triazines and pyrimidines

Related Child Applications (2)

Application Number	Title	Priority Date	Filing Date
CN 01120849 Division CN1250223C (zh)	1996-07-24	2001-05-30	吡咯并三嗪和嘧啶化合物
CN 02118589 Division CN1388126A (zh)	1996-07-24	2002-04-25	吡咯并三嗪和嘧啶化合物

Publications (2)

Publication Number	Publication Date
CN1225637A CN1225637A (zh)	1999-08-11
CN1104432C true CN1104432C (zh)	2003-04-02

Family

ID=27362048

Family Applications (3)

Application Number	Title	Priority Date	Filing Date
CN97196525A Expired - Lifetime CN1104432C (zh)	1996-07-24	1997-07-23	吡咯并三嗪和嘧啶化合物
CN 01120849 Expired - Lifetime CN1250223C (zh)	1996-07-24	2001-05-30	吡咯并三嗪和嘧啶化合物
CN 02118589 Pending CN1388126A (zh)	1996-07-24	2002-04-25	吡咯并三嗪和嘧啶化合物

Family Applications After (2)

Application Number	Title	Priority Date	Filing Date
CN 01120849 Expired - Lifetime CN1250223C (zh)	1996-07-24	2001-05-30	吡咯并三嗪和嘧啶化合物
CN 02118589 Pending CN1388126A (zh)	1996-07-24	2002-04-25	吡咯并三嗪和嘧啶化合物

Country Status (15)

Country	Link
JP (2)	JP4704521B2 (cs)
CN (3)	CN1104432C (cs)
AR (1)	AR049583A2 (cs)
BR (1)	BR9710544A (cs)
CA (1)	CA2259583C (cs)
CZ (1)	CZ299451B6 (cs)
EA (1)	EA004403B1 (cs)
EE (1)	EE04316B1 (cs)
HR (1)	HRP970413A2 (cs)
IL (4)	IL127871A0 (cs)
NO (1)	NO315610B3 (cs)
NZ (1)	NZ333777A (cs)
PL (1)	PL195762B1 (cs)
SI (1)	SI9720045B (cs)
SK (1)	SK286461B6 (cs)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
CN103694242A (zh) *	2013-12-10	2014-04-02	中国科学院昆明植物研究所	吡唑并嘧啶类化合物及其药物组合物和其在制药中的应用

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
NZ528207A (en) *	2001-03-13	2006-02-24	Bristol Myers Squibb Pharma Co	4-(2-butylamino)-2,7-dimethyl-8-(2-methyl-6-methoxypyrid-3-yl) pyrazolo-[1,5-A]-1,3,5-triazine, its enantiomers and pharmaceutically acceptable salts as corticotropin releasing factor receptor ligands
WO2004110454A1 (ja) *	2003-06-13	2004-12-23	Ishihara Sangyo Kaisha, Ltd.	アデノシンＡ2ａ受容体アゴニストの投与が必要な疾患を治療又は予防するための組成物
US7329662B2 (en) *	2003-10-03	2008-02-12	Hoffmann-La Roche Inc.	Pyrazolo-pyridine
GB0519957D0 (en) *	2005-09-30	2005-11-09	Sb Pharmco Inc	Chemical compound
HRP20100516T1 (hr) *	2006-09-20	2010-10-31	Eli Lilly And Company	Tiazolpirazolopirimidini kao antagonisti receptora crf1
WO2019036503A1 (en)	2017-08-14	2019-02-21	Spruce Biosciences, Inc.	CORTICOTROPIN RELEASE FACTOR RECEPTOR ANTAGONISTS
CN112028891B (zh) *	2019-07-30	2022-07-05	厦门宝太生物科技股份有限公司	腺苷受体拮抗剂
KR20240023691A (ko)	2020-08-12	2024-02-22	스프루스 바이오사이언시스 인코포레이티드	다낭성 난소 증후군을 치료하기 위한 방법 및 조성물
US11708372B2 (en)	2021-11-19	2023-07-25	Spruce Biosciences, Inc.	Crystalline composition of tildacerfont and methods of use and preparation thereof

Citations (3)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US3995039A (en) *	1975-05-27	1976-11-30	Merck & Co., Inc.	Pyrazolo [1,5-a] [1,3,5] triazines
US4824834A (en) *	1986-10-31	1989-04-25	Otsuka Pharmaceutical Company, Limited	Pyrazolotriazine compounds
EP0414200A2 (en) *	1989-08-25	1991-02-27	Otsuka Pharmaceutical Factory, Inc.	Salts of optically active 4-hydroxy-8-(3-lower alkoxy-4-phenylsulfinylphenyl)pyrazolo [1,5-a]-1,3,5-triazines and a process for production thereof

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
JPS6157587A (ja) *	1984-08-29	1986-03-24	Shionogi & Co Ltd	縮合複素環誘導体および抗潰瘍剤
WO1992006096A1 (fr) *	1990-10-09	1992-04-16	Otsuka Pharmaceutical Co., Ltd.	Derive de pyrimidine, production de ce derive et inhibiteur d'androgenes
AU651986B2 (en) *	1991-04-22	1994-08-11	Otsuka Pharmaceutical Factory, Inc.	Pyrazolo{1,5-a}pyrimidine derivative and anti-inflammatory containing the same
US5356897A (en) *	1991-09-09	1994-10-18	Fujisawa Pharmaceutical Co., Ltd.	3-(heteroaryl)-pyrazololi[1,5-a]pyrimidines

1997
- 1997-07-23 EA EA199900158A patent/EA004403B1/ru not_active IP Right Cessation
- 1997-07-23 JP JP50723398A patent/JP4704521B2/ja not_active Expired - Fee Related
- 1997-07-23 CZ CZ0018499A patent/CZ299451B6/cs not_active IP Right Cessation
- 1997-07-23 CN CN97196525A patent/CN1104432C/zh not_active Expired - Lifetime
- 1997-07-23 BR BR9710544A patent/BR9710544A/pt not_active IP Right Cessation
- 1997-07-23 EE EEP199900019A patent/EE04316B1/xx unknown
- 1997-07-23 NZ NZ333777A patent/NZ333777A/en not_active IP Right Cessation
- 1997-07-23 PL PL97331523A patent/PL195762B1/pl unknown
- 1997-07-23 IL IL12787197A patent/IL127871A0/xx unknown
- 1997-07-23 CA CA002259583A patent/CA2259583C/en not_active Expired - Lifetime
- 1997-07-23 SI SI9720045A patent/SI9720045B/sl active Search and Examination
- 1997-07-23 SK SK97-99A patent/SK286461B6/sk not_active IP Right Cessation
- 1997-07-24 HR HRP970413 patent/HRP970413A2/hr not_active Application Discontinuation
1998
- 1998-12-30 IL IL127871A patent/IL127871A/en not_active IP Right Cessation
1999
- 1999-01-21 NO NO19990264A patent/NO315610B3/no not_active IP Right Cessation
2001
- 2001-05-30 CN CN 01120849 patent/CN1250223C/zh not_active Expired - Lifetime
2002
- 2002-04-25 CN CN 02118589 patent/CN1388126A/zh active Pending
- 2002-06-11 IL IL150163A patent/IL150163A/en not_active IP Right Cessation
2004
- 2004-07-23 JP JP2004216483A patent/JP4194539B2/ja not_active Expired - Fee Related
- 2004-10-12 IL IL164513A patent/IL164513A/en not_active IP Right Cessation
2005
- 2005-07-11 AR ARP050102868A patent/AR049583A2/es not_active Application Discontinuation

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US3995039A (en) *	1975-05-27	1976-11-30	Merck & Co., Inc.	Pyrazolo [1,5-a] [1,3,5] triazines
US4824834A (en) *	1986-10-31	1989-04-25	Otsuka Pharmaceutical Company, Limited	Pyrazolotriazine compounds
EP0414200A2 (en) *	1989-08-25	1991-02-27	Otsuka Pharmaceutical Factory, Inc.	Salts of optically active 4-hydroxy-8-(3-lower alkoxy-4-phenylsulfinylphenyl)pyrazolo [1,5-a]-1,3,5-triazines and a process for production thereof

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
CN103694242A (zh) *	2013-12-10	2014-04-02	中国科学院昆明植物研究所	吡唑并嘧啶类化合物及其药物组合物和其在制药中的应用
CN103694242B (zh) *	2013-12-10	2016-01-06	昆明翔昊科技有限公司	吡唑并嘧啶类化合物及其药物组合物和其在制药中的应用

Also Published As

Publication number	Publication date
IL164513A (en)	2010-04-29
CZ18499A3 (cs)	1999-11-17
JP4704521B2 (ja)	2011-06-15
CN1250223C (zh)	2006-04-12
SK9799A3 (sk)	2005-04-01
EE9900019A (et)	1999-08-16
IL164513A0 (en)	2005-12-18
NO990264L (no)	1999-03-10
NO990264D0 (no)	1999-01-21
PL195762B1 (pl)	2007-10-31
IL127871A0 (en)	1999-10-28
BR9710544A (pt)	1999-08-17
CZ299451B6 (cs)	2008-07-30
EA199900158A1 (ru)	1999-10-28
HRP970413A2 (en)	1998-10-31
IL150163A (en)	2010-12-30
NO315610B1 (no)	2003-09-29
CN1225637A (zh)	1999-08-11
EA004403B1 (ru)	2004-04-29
JP2002513382A (ja)	2002-05-08
CA2259583C (en)	2009-11-17
EE04316B1 (et)	2004-06-15
SI9720045A (sl)	1999-10-31
CN1327793A (zh)	2001-12-26
SK286461B6 (sk)	2008-10-07
SI9720045B (sl)	2008-02-29
JP4194539B2 (ja)	2008-12-10
JP2005097257A (ja)	2005-04-14
IL127871A (en)	2010-04-29
CN1388126A (zh)	2003-01-01
AR049583A2 (es)	2006-08-16
CA2259583A1 (en)	1998-01-29
PL331523A1 (en)	1999-07-19
NO315610B3 (no)	2003-09-29
NZ333777A (en)	2000-07-28

Legal Events

Date	Code	Title	Description
1999-08-11	C06	Publication
1999-08-11	PB01	Publication
1999-10-20	C10	Entry into substantive examination
1999-10-20	SE01	Entry into force of request for substantive examination
2003-04-02	C14	Grant of patent or utility model
2003-04-02	GR01	Patent grant
2017-08-25	CX01	Expiry of patent term
2017-08-25	CX01	Expiry of patent term	Granted publication date: 20030402

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