CN1124928A - P-选择蛋白抗体及其应用 - Google Patents

P-选择蛋白抗体及其应用 Download PDF

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Publication number
CN1124928A
CN1124928A CN94192352A CN94192352A CN1124928A CN 1124928 A CN1124928 A CN 1124928A CN 94192352 A CN94192352 A CN 94192352A CN 94192352 A CN94192352 A CN 94192352A CN 1124928 A CN1124928 A CN 1124928A
Authority
CN
China
Prior art keywords
antibody
variable region
light chain
humanized immunoglobulin
immunoglobulin
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN94192352A
Other languages
English (en)
Chinese (zh)
Inventor
罗伯特·W·切斯纳特
玛格丽特·J·波利
S·塔兰·琼斯
乔斯·W·萨尔丹那
玛丽·M·斑迪格
迈克尔·克赖格勒尔
卡尔·佩里茨
罗伯特·拜尔
迈克尔·努恩
詹姆斯·C·波尔森
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Cytel Corp
Original Assignee
Cytel Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from PCT/US1993/004272 external-priority patent/WO1994023317A1/fr
Priority claimed from US08/202,047 external-priority patent/US5800815A/en
Application filed by Cytel Corp filed Critical Cytel Corp
Priority claimed from PCT/US1994/004935 external-priority patent/WO1994025067A1/fr
Publication of CN1124928A publication Critical patent/CN1124928A/zh
Pending legal-status Critical Current

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/7056—Lectin superfamily, e.g. CD23, CD72
    • C07K14/70564—Selectins, e.g. CD62
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2851—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the lectin superfamily, e.g. CD23, CD72
    • C07K16/2854—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the lectin superfamily, e.g. CD23, CD72 against selectins, e.g. CD62
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/24—Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Cell Biology (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
CN94192352A 1993-05-04 1994-05-04 P-选择蛋白抗体及其应用 Pending CN1124928A (zh)

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
PCT/US1993/004272 WO1994023317A1 (fr) 1993-03-31 1993-05-04 Guide-d'ondes optique maintenant la polarisation asymetrique et procede pour sa fabrication
WOPCT/US93/04272 1993-05-04
US5729293A 1993-05-05 1993-05-05
US08/057,292 1993-05-05
US08/202,047 US5800815A (en) 1903-05-05 1994-02-25 Antibodies to P-selectin and their uses
US08/202,047 1994-02-25
PCT/US1994/004935 WO1994025067A1 (fr) 1993-05-04 1994-05-04 Anticorps diriges contre la selectine p et leurs utilisations

Publications (1)

Publication Number Publication Date
CN1124928A true CN1124928A (zh) 1996-06-19

Family

ID=26736298

Family Applications (1)

Application Number Title Priority Date Filing Date
CN94192352A Pending CN1124928A (zh) 1993-05-04 1994-05-04 P-选择蛋白抗体及其应用

Country Status (8)

Country Link
CN (1) CN1124928A (fr)
CA (1) CA2162149C (fr)
CZ (1) CZ287295A3 (fr)
HU (1) HUT75894A (fr)
NO (1) NO954403L (fr)
NZ (1) NZ266934A (fr)
PL (1) PL311666A1 (fr)
SK (1) SK137795A3 (fr)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103874503A (zh) * 2010-12-21 2014-06-18 瑟莱克斯制药公司 抗p-选择素抗体及其使用和鉴定方法
CN1984680B (zh) * 2004-05-10 2014-11-05 艾比吉诺米克斯合作公司 抗体

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN113952468B (zh) * 2021-09-26 2023-07-07 中国人民解放军空军军医大学 一种治疗心肌缺血再灌注损伤的环孢菌素a纳米药物

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1984680B (zh) * 2004-05-10 2014-11-05 艾比吉诺米克斯合作公司 抗体
CN103874503A (zh) * 2010-12-21 2014-06-18 瑟莱克斯制药公司 抗p-选择素抗体及其使用和鉴定方法

Also Published As

Publication number Publication date
NO954403L (no) 1996-01-03
HUT75894A (en) 1997-05-28
PL311666A1 (en) 1996-03-04
CA2162149A1 (fr) 1994-11-10
HU9503156D0 (en) 1996-01-29
CZ287295A3 (en) 1996-05-15
NZ266934A (en) 1997-07-27
NO954403D0 (no) 1995-11-03
SK137795A3 (en) 1996-11-06
CA2162149C (fr) 2007-07-10

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