CN1128997A - 新的二烷氧基-吡啶基-苯并咪唑衍生物 - Google Patents

新的二烷氧基-吡啶基-苯并咪唑衍生物 Download PDF

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Publication number
CN1128997A
CN1128997A CN95190482A CN95190482A CN1128997A CN 1128997 A CN1128997 A CN 1128997A CN 95190482 A CN95190482 A CN 95190482A CN 95190482 A CN95190482 A CN 95190482A CN 1128997 A CN1128997 A CN 1128997A
Authority
CN
China
Prior art keywords
methyl
pyridyl
benzimidazole
sulfinyl
dimethoxy
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN95190482A
Other languages
English (en)
Chinese (zh)
Inventor
P·林堡
G·E·森登
P·O·S·冯昂格
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
AstraZeneca AB
Original Assignee
Astra AB
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Astra AB filed Critical Astra AB
Publication of CN1128997A publication Critical patent/CN1128997A/zh
Pending legal-status Critical Current

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
    • A61K31/4439—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. omeprazole
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
CN95190482A 1994-05-27 1995-05-11 新的二烷氧基-吡啶基-苯并咪唑衍生物 Pending CN1128997A (zh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
SE9400511 1994-05-27
WOPCT/SE94/00511 1994-05-27

Publications (1)

Publication Number Publication Date
CN1128997A true CN1128997A (zh) 1996-08-14

Family

ID=20392945

Family Applications (1)

Application Number Title Priority Date Filing Date
CN95190482A Pending CN1128997A (zh) 1994-05-27 1995-05-11 新的二烷氧基-吡啶基-苯并咪唑衍生物

Country Status (18)

Country Link
EP (1) EP0712401A1 (fr)
JP (1) JPH09504557A (fr)
CN (1) CN1128997A (fr)
AU (1) AU2633095A (fr)
BR (1) BR9506235A (fr)
CA (1) CA2166988A1 (fr)
CZ (1) CZ24396A3 (fr)
EE (1) EE9600011A (fr)
FI (1) FI960367A0 (fr)
HU (1) HU9600005D0 (fr)
IL (1) IL113604A0 (fr)
IS (1) IS4321A (fr)
MA (1) MA23563A1 (fr)
NO (1) NO960268L (fr)
PL (1) PL312692A1 (fr)
TN (1) TNSN95062A1 (fr)
WO (1) WO1995032959A1 (fr)
ZA (1) ZA954125B (fr)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9423968D0 (en) * 1994-11-28 1995-01-11 Astra Ab Resolution
GB9423970D0 (en) * 1994-11-28 1995-01-11 Astra Ab Oxidation
US5840737A (en) 1996-01-04 1998-11-24 The Curators Of The University Of Missouri Omeprazole solution and method for using same
US6489346B1 (en) 1996-01-04 2002-12-03 The Curators Of The University Of Missouri Substituted benzimidazole dosage forms and method of using same
IL142629A0 (en) * 1998-11-18 2002-03-10 Astra Ab Improved chemical process and pharmaceutical formulation
US8206741B2 (en) 2001-06-01 2012-06-26 Pozen Inc. Pharmaceutical compositions for the coordinated delivery of NSAIDs
US8993599B2 (en) 2003-07-18 2015-03-31 Santarus, Inc. Pharmaceutical formulations useful for inhibiting acid secretion and methods for making and using them
US8906940B2 (en) 2004-05-25 2014-12-09 Santarus, Inc. Pharmaceutical formulations useful for inhibiting acid secretion and methods for making and using them
WO2008057802A2 (fr) 2006-10-27 2008-05-15 The Curators Of The University Of Missouri Compositions comprenant des agents d'inhibition de la pompe à protons labiles d'acide, au moins un autre agent pharmaceutiquement actif et leurs procédés d'utilisation
CA2716367C (fr) 2008-02-20 2015-05-26 The Curators Of The University Of Missouri Composition comprenant une combinaison d'omeprazole et de lansoprazole, et un agent tampon, et ses methodes d'utilisation
AU2009290712A1 (en) 2008-09-09 2010-03-18 Astrazeneca Ab Method for delivering a pharmaceutical composition to patient in need thereof
CA2764963C (fr) 2009-06-25 2016-11-01 Astrazeneca Ab Procede pour le traitement d'un patient a risque de developer un ulcere associe a nsaid
BR112014016085A8 (pt) 2011-12-28 2017-07-04 Pozen Inc composições aprimoradas e métodos para distribuição de omeprazol mais ácido acetilsalicílico

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU649456B2 (en) * 1990-06-20 1994-05-26 Astra Aktiebolag Dialkoxy-pyridinyl-benzimidazole derivatives, process for their preparation and their pharmaceutical use
DE4035455A1 (de) * 1990-11-08 1992-05-14 Byk Gulden Lomberg Chem Fab Enantiomerentrennung

Also Published As

Publication number Publication date
FI960367A7 (fi) 1996-01-26
JPH09504557A (ja) 1997-05-06
EP0712401A1 (fr) 1996-05-22
ZA954125B (en) 1995-11-27
HU9600005D0 (en) 1996-03-28
FI960367L (fi) 1996-01-26
EE9600011A (et) 1996-04-15
MA23563A1 (fr) 1995-12-31
NO960268D0 (no) 1996-01-23
AU2633095A (en) 1995-12-21
NO960268L (no) 1996-01-23
TNSN95062A1 (fr) 1996-02-06
IL113604A0 (en) 1995-08-31
CZ24396A3 (en) 1996-06-12
BR9506235A (pt) 1997-08-12
CA2166988A1 (fr) 1995-12-07
WO1995032959A1 (fr) 1995-12-07
FI960367A0 (fi) 1996-01-26
IS4321A (is) 1996-01-17
PL312692A1 (en) 1996-05-13

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Legal Events

Date Code Title Description
C06 Publication
PB01 Publication
C01 Deemed withdrawal of patent application (patent law 1993)
WD01 Invention patent application deemed withdrawn after publication