JPH09504557A - 新規なジアルコキシ−ピリジニル−ベンズイミダゾール誘導体 - Google Patents

新規なジアルコキシ−ピリジニル−ベンズイミダゾール誘導体

Info

Publication number
JPH09504557A
JPH09504557A JP8500730A JP50073095A JPH09504557A JP H09504557 A JPH09504557 A JP H09504557A JP 8500730 A JP8500730 A JP 8500730A JP 50073095 A JP50073095 A JP 50073095A JP H09504557 A JPH09504557 A JP H09504557A
Authority
JP
Japan
Prior art keywords
methyl
benzimidazole
compound
pyridinyl
sulfinyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP8500730A
Other languages
English (en)
Japanese (ja)
Inventor
リンドベルイ，ペル・レンナート
スンデーン，グンネル・エリーサベト
ヴオン・ウンゲ，ペル・オスカル・スヴエルケル
Original Assignee
アストラ・アクチエボラーグ
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by アストラ・アクチエボラーグ filed Critical アストラ・アクチエボラーグ
Publication of JPH09504557A publication Critical patent/JPH09504557A/ja
Pending legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
    • A61K31/4439—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. omeprazole
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
JP8500730A 1994-05-27 1995-05-11 新規なジアルコキシ−ピリジニル−ベンズイミダゾール誘導体 Pending JPH09504557A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
SE9400511 1994-05-27
AT94/00511 1994-05-27
PCT/SE1995/000519 WO1995032959A1 (fr) 1994-05-27 1995-05-11 Nouveaux derives de dialcoxy-pyridinyl-benzimidazole

Publications (1)

Publication Number Publication Date
JPH09504557A true JPH09504557A (ja) 1997-05-06

Family

ID=20392945

Family Applications (1)

Application Number Title Priority Date Filing Date
JP8500730A Pending JPH09504557A (ja) 1994-05-27 1995-05-11 新規なジアルコキシ−ピリジニル−ベンズイミダゾール誘導体

Country Status (18)

Country Link
EP (1) EP0712401A1 (fr)
JP (1) JPH09504557A (fr)
CN (1) CN1128997A (fr)
AU (1) AU2633095A (fr)
BR (1) BR9506235A (fr)
CA (1) CA2166988A1 (fr)
CZ (1) CZ24396A3 (fr)
EE (1) EE9600011A (fr)
FI (1) FI960367L (fr)
HU (1) HU9600005D0 (fr)
IL (1) IL113604A0 (fr)
IS (1) IS4321A (fr)
MA (1) MA23563A1 (fr)
NO (1) NO960268L (fr)
PL (1) PL312692A1 (fr)
TN (1) TNSN95062A1 (fr)
WO (1) WO1995032959A1 (fr)
ZA (1) ZA954125B (fr)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9423970D0 (en) * 1994-11-28 1995-01-11 Astra Ab Oxidation
GB9423968D0 (en) * 1994-11-28 1995-01-11 Astra Ab Resolution
US5840737A (en) 1996-01-04 1998-11-24 The Curators Of The University Of Missouri Omeprazole solution and method for using same
US6489346B1 (en) 1996-01-04 2002-12-03 The Curators Of The University Of Missouri Substituted benzimidazole dosage forms and method of using same
ATE271556T1 (de) * 1998-11-18 2004-08-15 Astrazeneca Ab Verbesserter chemischer prozess und eine pharmazeutische zubereitung
US8206741B2 (en) 2001-06-01 2012-06-26 Pozen Inc. Pharmaceutical compositions for the coordinated delivery of NSAIDs
US8993599B2 (en) 2003-07-18 2015-03-31 Santarus, Inc. Pharmaceutical formulations useful for inhibiting acid secretion and methods for making and using them
US8906940B2 (en) 2004-05-25 2014-12-09 Santarus, Inc. Pharmaceutical formulations useful for inhibiting acid secretion and methods for making and using them
EP2086543A2 (fr) 2006-10-27 2009-08-12 The Curators of the University of Missouri Compositions comprenant des agents d'inhibition de la pompe à protons labiles d'acide, au moins un autre agent pharmaceutiquement actif et leurs procédés d'utilisation
JP2011512416A (ja) 2008-02-20 2011-04-21 ザ・キュレイターズ・オブ・ザ・ユニバーシティー・オブ・ミズーリ オメプラゾール及びランソプラゾールの組合せと緩衝剤を含んでなる組成物とそれを使用する方法
BRPI0918492A2 (pt) 2008-09-09 2015-12-01 Astrazeneca Ab uso de naproxen, ou sal farmaceuticamente aceitável do mesmo, e esomeprazol, ou sal farmaceuticamente aceitável do mesmo
EP2445499A4 (fr) 2009-06-25 2013-02-27 Astrazeneca Ab Procede pour le traitement d'un patient a risque de developer un ulcere associe a nsaid
UA115139C2 (uk) 2011-12-28 2017-09-25 Поузен Інк. Спосіб доставки фармацевтичної композиції, яка містить омепразол й ацетилсаліцилову кислоту, пацієнту

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE69131627T2 (de) * 1990-06-20 2000-04-27 Astra Ab Soedertaelje Dialkoxypyridinylbenzimidazolderivate, verfahren zur herstellung und ihre pharmazeutische verwendung
DE4035455A1 (de) * 1990-11-08 1992-05-14 Byk Gulden Lomberg Chem Fab Enantiomerentrennung

Also Published As

Publication number Publication date
HU9600005D0 (en) 1996-03-28
FI960367A0 (fi) 1996-01-26
CN1128997A (zh) 1996-08-14
NO960268D0 (no) 1996-01-23
WO1995032959A1 (fr) 1995-12-07
CZ24396A3 (en) 1996-06-12
TNSN95062A1 (fr) 1996-02-06
NO960268L (no) 1996-01-23
FI960367A7 (fi) 1996-01-26
PL312692A1 (en) 1996-05-13
ZA954125B (en) 1995-11-27
MA23563A1 (fr) 1995-12-31
IL113604A0 (en) 1995-08-31
IS4321A (is) 1996-01-17
EP0712401A1 (fr) 1996-05-22
FI960367L (fi) 1996-01-26
CA2166988A1 (fr) 1995-12-07
EE9600011A (et) 1996-04-15
BR9506235A (pt) 1997-08-12
AU2633095A (en) 1995-12-21

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