CN112996486A - 包含细胞穿透肽的治疗剂的局部递送用于治疗年龄相关性黄斑变性及其它眼病 - Google Patents
包含细胞穿透肽的治疗剂的局部递送用于治疗年龄相关性黄斑变性及其它眼病 Download PDFInfo
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- CN112996486A CN112996486A CN201880059888.2A CN201880059888A CN112996486A CN 112996486 A CN112996486 A CN 112996486A CN 201880059888 A CN201880059888 A CN 201880059888A CN 112996486 A CN112996486 A CN 112996486A
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- A—HUMAN NECESSITIES
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- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
- A61K47/62—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being a protein, peptide or polyamino acid
- A61K47/64—Drug-peptide, drug-protein or drug-polyamino acid conjugates, i.e. the modifying agent being a peptide, protein or polyamino acid which is covalently bonded or complexed to a therapeutically active agent
- A61K47/645—Polycationic or polyanionic oligopeptides, polypeptides or polyamino acids, e.g. polylysine, polyarginine, polyglutamic acid or peptide TAT
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- A61K38/1703—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
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- A61K39/3955—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against proteinaceous materials, e.g. enzymes, hormones, lymphokines
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- C—CHEMISTRY; METALLURGY
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- C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/22—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against growth factors ; against growth regulators
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/24—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
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- C07K2319/00—Fusion polypeptide
- C07K2319/01—Fusion polypeptide containing a localisation/targetting motif
- C07K2319/10—Fusion polypeptide containing a localisation/targetting motif containing a tag for extracellular membrane crossing, e.g. TAT or VP22
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- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Organic Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
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- Molecular Biology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Biochemistry (AREA)
- Ophthalmology & Optometry (AREA)
- Biophysics (AREA)
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- Endocrinology (AREA)
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- Microbiology (AREA)
- Mycology (AREA)
- Marine Sciences & Fisheries (AREA)
- Zoology (AREA)
- Gastroenterology & Hepatology (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicinal Preparation (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201762533231P | 2017-07-17 | 2017-07-17 | |
| US62/533,231 | 2017-07-17 | ||
| PCT/US2018/042410 WO2019018350A1 (en) | 2017-07-17 | 2018-07-17 | TOPICAL ADMINISTRATION OF THERAPEUTIC AGENTS COMPRISING CELL PENETRATION PEPTIDES, FOR USE IN THE TREATMENT OF AGE-RELATED MACULAR DEGENERATION AND OTHER OCULAR DISEASES |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN112996486A true CN112996486A (zh) | 2021-06-18 |
Family
ID=63104068
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201880059888.2A Pending CN112996486A (zh) | 2017-07-17 | 2018-07-17 | 包含细胞穿透肽的治疗剂的局部递送用于治疗年龄相关性黄斑变性及其它眼病 |
Country Status (8)
| Country | Link |
|---|---|
| US (2) | US10905770B2 (2) |
| EP (1) | EP3654941A1 (2) |
| JP (1) | JP2020528082A (2) |
| CN (1) | CN112996486A (2) |
| AU (1) | AU2018302022A1 (2) |
| CA (1) | CA3070241A1 (2) |
| IL (1) | IL272105A (2) |
| WO (1) | WO2019018350A1 (2) |
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| KR20200134287A (ko) * | 2018-04-02 | 2020-12-01 | 젠켐 테크놀로지 컴퍼니 리미티드 (베이징) | 타겟성을 구비하는 세포막 투과 펩타이드-다중팔 폴리에틸렌글리콜-약물 켤레체 및 그 응용 |
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| CN118995345B (zh) * | 2024-08-09 | 2025-09-26 | 山西医科大学 | 一种抑制角膜缺氧损伤和角膜新生血管的隐形眼镜护理液及其制备方法 |
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Also Published As
| Publication number | Publication date |
|---|---|
| AU2018302022A1 (en) | 2020-02-27 |
| CA3070241A1 (en) | 2019-01-24 |
| EP3654941A1 (en) | 2020-05-27 |
| IL272105A (en) | 2020-03-31 |
| US20190015521A1 (en) | 2019-01-17 |
| US10905770B2 (en) | 2021-02-02 |
| WO2019018350A1 (en) | 2019-01-24 |
| US20210085797A1 (en) | 2021-03-25 |
| JP2020528082A (ja) | 2020-09-17 |
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