CN1150423A - 新型紫杉化合物、其制备方法及其药物组合物 - Google Patents

新型紫杉化合物、其制备方法及其药物组合物 Download PDF

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Publication number
CN1150423A
CN1150423A CN95193482A CN95193482A CN1150423A CN 1150423 A CN1150423 A CN 1150423A CN 95193482 A CN95193482 A CN 95193482A CN 95193482 A CN95193482 A CN 95193482A CN 1150423 A CN1150423 A CN 1150423A
Authority
CN
China
Prior art keywords
group
alkyl
atom
phenyl
compound
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN95193482A
Other languages
English (en)
Chinese (zh)
Inventor
H·布查德
J-D·伯扎特
A·科默康
C·特里尔
M·朱克
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Aventis Pharma SA
Original Assignee
Rhone Poulenc Rorer SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Rhone Poulenc Rorer SA filed Critical Rhone Poulenc Rorer SA
Publication of CN1150423A publication Critical patent/CN1150423A/zh
Pending legal-status Critical Current

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D305/00—Heterocyclic compounds containing four-membered rings having one oxygen atom as the only ring hetero atoms
    • C07D305/14—Heterocyclic compounds containing four-membered rings having one oxygen atom as the only ring hetero atoms condensed with carbocyclic rings or ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Epoxy Compounds (AREA)
CN95193482A 1994-06-09 1995-06-07 新型紫杉化合物、其制备方法及其药物组合物 Pending CN1150423A (zh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR94/07049 1994-06-09
FR9407049A FR2721023B1 (fr) 1994-06-09 1994-06-09 Nouveaux Taxoïdes, leur préparation et les compositions pharmaceutiques qui les contiennent.

Publications (1)

Publication Number Publication Date
CN1150423A true CN1150423A (zh) 1997-05-21

Family

ID=9464032

Family Applications (1)

Application Number Title Priority Date Filing Date
CN95193482A Pending CN1150423A (zh) 1994-06-09 1995-06-07 新型紫杉化合物、其制备方法及其药物组合物

Country Status (14)

Country Link
EP (1) EP0764154A1 (cs)
JP (1) JPH10500979A (cs)
CN (1) CN1150423A (cs)
AU (1) AU692269B2 (cs)
CA (1) CA2190651A1 (cs)
CZ (1) CZ358396A3 (cs)
FI (1) FI964900A0 (cs)
FR (1) FR2721023B1 (cs)
HU (1) HUT77224A (cs)
PL (1) PL317467A1 (cs)
SK (1) SK158096A3 (cs)
TW (1) TW318845B (cs)
WO (1) WO1995033736A1 (cs)
ZA (1) ZA954655B (cs)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5919815A (en) * 1996-05-22 1999-07-06 Neuromedica, Inc. Taxane compounds and compositions
US5795909A (en) 1996-05-22 1998-08-18 Neuromedica, Inc. DHA-pharmaceutical agent conjugates of taxanes
ES2151277T3 (es) * 1996-05-22 2000-12-16 Protarga Inc Composiciones que comprenden conjugados de acido cis-docosahexaenoico y taxotere.
FR2750989B1 (fr) * 1996-07-09 1998-09-25 Rhone Poulenc Rorer Sa Procede de monoacylation d'hydroxy taxanes
US5773464A (en) * 1996-09-30 1998-06-30 Bristol-Myers Squibb Company C-10 epoxy taxanes
WO1998017656A1 (en) 1996-10-24 1998-04-30 Institute Armand-Frappier A family of canadensol taxanes, the semi-synthetic preparation and therapeutic use thereof
US6495579B1 (en) 1996-12-02 2002-12-17 Angiotech Pharmaceuticals, Inc. Method for treating multiple sclerosis
US7235583B1 (en) 1999-03-09 2007-06-26 Luitpold Pharmaceuticals, Inc., Fatty acid-anticancer conjugates and uses thereof
US6613083B2 (en) 2001-05-02 2003-09-02 Eckhard Alt Stent device and method
US6956124B2 (en) 2003-04-14 2005-10-18 Aventis Pharma S.A. Process for the preparation of 4,10β-diacetoxy-2α-benzoyloxy-5β,20-epoxy-1,13α-dihydroxy-9-oxo-19-norcyclopropa[g]tax-11-ene
FR2853651B1 (fr) * 2003-04-14 2005-05-20 Aventis Pharma Sa Procede de preparation du 4,10 beta-diacetoxy-2 alpha- benzoyloxy-5 beta, 20-epoxy-1, 13 alpha-dihydroxy-9-oxo-19- norcyclopropa[g]tax-11-ene

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE256115T1 (de) * 1992-07-01 2003-12-15 Bristol Myers Squibb Co 7,8-zyklopropataxanen mit antitumor wirkung
US5254580A (en) * 1993-01-19 1993-10-19 Bristol-Myers Squibb Company 7,8-cyclopropataxanes
FR2698871B1 (fr) * 1992-12-09 1995-02-24 Rhone Poulenc Rorer Sa Nouveau taxoïdes, leur préparation et les compositions pharmaceutiques qui les contiennent.

Also Published As

Publication number Publication date
AU2741795A (en) 1996-01-04
SK158096A3 (en) 1997-07-09
HU9603388D0 (en) 1997-01-28
ZA954655B (en) 1996-02-13
CA2190651A1 (fr) 1995-12-14
CZ358396A3 (en) 1997-03-12
HUT77224A (hu) 1998-03-02
WO1995033736A1 (fr) 1995-12-14
FI964900A7 (fi) 1996-12-05
FR2721023B1 (fr) 1996-07-12
EP0764154A1 (fr) 1997-03-26
AU692269B2 (en) 1998-06-04
JPH10500979A (ja) 1998-01-27
PL317467A1 (en) 1997-04-14
FI964900A0 (fi) 1996-12-05
FR2721023A1 (fr) 1995-12-15
TW318845B (cs) 1997-11-01

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Legal Events

Date Code Title Description
C06 Publication
PB01 Publication
C10 Entry into substantive examination
SE01 Entry into force of request for substantive examination
C01 Deemed withdrawal of patent application (patent law 1993)
WD01 Invention patent application deemed withdrawn after publication