CN1245512C - 含重组菌毛蛋白的抗淋病奈瑟氏球茵或脑膜炎奈瑟氏球菌的疫苗 - Google Patents

含重组菌毛蛋白的抗淋病奈瑟氏球茵或脑膜炎奈瑟氏球菌的疫苗 Download PDF

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Publication number
CN1245512C
CN1245512C CNB998056014A CN99805601A CN1245512C CN 1245512 C CN1245512 C CN 1245512C CN B998056014 A CNB998056014 A CN B998056014A CN 99805601 A CN99805601 A CN 99805601A CN 1245512 C CN1245512 C CN 1245512C
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China
Prior art keywords
protein
recombinant
pili
class
pilus
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Expired - Fee Related
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CNB998056014A
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English (en)
Chinese (zh)
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CN1298446A (zh
Inventor
T·N·梅特卡夫三世
R·J·扎古尔斯基
P·奥依
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Wyeth Holdings LLC
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American Cyanamid Co
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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/22—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Neisseriaceae (F)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/01—Fusion polypeptide containing a localisation/targetting motif
    • C07K2319/02—Fusion polypeptide containing a localisation/targetting motif containing a signal sequence

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Medicinal Chemistry (AREA)
  • Communicable Diseases (AREA)
  • Plant Pathology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Oncology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Physics & Mathematics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Microbiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
CNB998056014A 1998-04-29 1999-04-29 含重组菌毛蛋白的抗淋病奈瑟氏球茵或脑膜炎奈瑟氏球菌的疫苗 Expired - Fee Related CN1245512C (zh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US8340598P 1998-04-29 1998-04-29
US60/083,405 1998-04-29

Publications (2)

Publication Number Publication Date
CN1298446A CN1298446A (zh) 2001-06-06
CN1245512C true CN1245512C (zh) 2006-03-15

Family

ID=22178094

Family Applications (1)

Application Number Title Priority Date Filing Date
CNB998056014A Expired - Fee Related CN1245512C (zh) 1998-04-29 1999-04-29 含重组菌毛蛋白的抗淋病奈瑟氏球茵或脑膜炎奈瑟氏球菌的疫苗

Country Status (9)

Country Link
EP (1) EP1073748A2 (fr)
JP (1) JP2002527041A (fr)
KR (4) KR20060118628A (fr)
CN (1) CN1245512C (fr)
AU (2) AU3968599A (fr)
BR (1) BR9910005A (fr)
CA (1) CA2325055A1 (fr)
IL (1) IL139311A0 (fr)
WO (1) WO1999055875A2 (fr)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0011108D0 (en) * 2000-05-08 2000-06-28 Microscience Ltd Virulence gene and protein and their use
GB0118249D0 (en) * 2001-07-26 2001-09-19 Chiron Spa Histidine vaccines
ATE493510T1 (de) * 2004-04-08 2011-01-15 State Of Queensland Acting Through Queensland Health Nachweis von neisseria gonorrhoeae
WO2010027729A2 (fr) * 2008-08-25 2010-03-11 Creatv Microtech, Inc. Vaccins gonococciques
US9802988B2 (en) * 2009-05-20 2017-10-31 University Of Maryland, Baltimore Engineered type IV pilin of Clostridium difficile
WO2012059593A1 (fr) * 2010-11-05 2012-05-10 Institut National De La Sante Et De La Recherche Medicale (Inserm) Vaccins pour la prévention d'infections à méningocoque
JP5991740B2 (ja) * 2012-06-21 2016-09-14 キヤノン株式会社 ライセンス管理装置、ライセンス管理方法、およびプログラム
WO2014016152A1 (fr) * 2012-07-27 2014-01-30 Institut National De La Sante Et De La Recherche Medicale Utilisation du cd147 comme récepteur pour l'adhésion impliquant les pili des méningocoques à l'endothélium vasculaire
CN103405760A (zh) * 2013-06-19 2013-11-27 中国科学院海洋研究所 迟缓爱德华氏菌菌毛蛋白FimA的应用
CN106290849A (zh) * 2015-05-13 2017-01-04 上海凯创生物技术有限公司 一种脑膜炎菌胶体金检测试剂盒
CN118994336B (zh) * 2024-10-22 2025-01-24 四川大学华西医院 鲍曼不动杆菌菌毛重组蛋白抗原、制备方法及其应用

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE841068A (fr) * 1975-04-25 1976-10-25 Procede de preparation de cristaux de poils gonococciques et leurs applications a la detection et a la prevention des infections dues a neisseria gonorrhoeae
EP0049945A3 (fr) * 1980-09-15 1982-12-01 Bactex Incorporated Méthode pour la détermination de la hiérarchie des organismes piliés et vaccin préparé à partir de ces organismes
US4443431A (en) * 1981-05-27 1984-04-17 The United States Of America As Represented By The Department Of Health And Human Services Neisseria gonorrhoeae vaccine
EP0177583A4 (fr) * 1984-04-06 1988-06-08 Scripps Clinic Res Vaccin ou procede de diagnostic utilisant un peptide et polypeptide indique pour cette utilisation.
CU22302A1 (es) * 1990-09-07 1995-01-31 Cigb Secuencia nucleotidica codificante para una proteina de la membrana externa de neisseria meningitidis y uso de dicha proteina en preparados vacunales
WO1992013871A1 (fr) * 1991-01-31 1992-08-20 Washington University Polypeptides et polynucleotides utiles pour le diagnostic et le traitement de neisseria pathogene
AU3416693A (en) * 1991-12-18 1993-07-19 State Of Oregon Acting By And Through The Oregon State Board Of Higher Education On Behalf Of Oregon State University, The Antigenic preparations that stimulate production of antibodies which bind to the pili of type IV piliated bacteria
CA2138997C (fr) * 1992-06-25 2003-06-03 Jean-Paul Prieels Composition vaccinale qui contient des adjuvants
WO1994008013A1 (fr) * 1992-10-07 1994-04-14 State Of Oregon, Acting By And Through The Oregon State Board Of Higher Education On Behalf Of The Oregon Health Sciences University Variantes de piline et leurs utilisations
US6265567B1 (en) * 1995-04-07 2001-07-24 University Of North Carolina At Chapel Hill Isolated FrpB nucleic acid molecule

Also Published As

Publication number Publication date
KR20060118629A (ko) 2006-11-23
KR20010043105A (ko) 2001-05-25
AU2003204738B2 (en) 2006-09-14
JP2002527041A (ja) 2002-08-27
CA2325055A1 (fr) 1999-11-04
CN1298446A (zh) 2001-06-06
KR20060118630A (ko) 2006-11-23
KR20060118628A (ko) 2006-11-23
IL139311A0 (en) 2001-11-25
WO1999055875A3 (fr) 2000-04-13
AU3968599A (en) 1999-11-16
EP1073748A2 (fr) 2001-02-07
BR9910005A (pt) 2001-01-16
WO1999055875A2 (fr) 1999-11-04

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