CN1368977A - 不饱和胆甾烷衍生物及其在制备调节减数分裂的药物中的应用 - Google Patents

不饱和胆甾烷衍生物及其在制备调节减数分裂的药物中的应用 Download PDF

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Publication number
CN1368977A
CN1368977A CN00803662A CN00803662A CN1368977A CN 1368977 A CN1368977 A CN 1368977A CN 00803662 A CN00803662 A CN 00803662A CN 00803662 A CN00803662 A CN 00803662A CN 1368977 A CN1368977 A CN 1368977A
Authority
CN
China
Prior art keywords
dimethyl
cholestane
dien
hydrogen atom
compound
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN00803662A
Other languages
English (en)
Chinese (zh)
Inventor
托尔斯滕·布卢姆
彼得·埃斯佩林
约阿希姆·库恩克
赫丽斯塔·黑格勒－哈通
莫尼卡·莱瑟
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Bayer Pharma AG
Original Assignee
Schering AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Schering AG filed Critical Schering AG
Publication of CN1368977A publication Critical patent/CN1368977A/zh
Pending legal-status Critical Current

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J43/00—Normal steroids having a nitrogen-containing hetero ring spiro-condensed or not condensed with the cyclopenta(a)hydrophenanthrene skeleton
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/08—Drugs for genital or sexual disorders; Contraceptives for gonadal disorders or for enhancing fertility, e.g. inducers of ovulation or of spermatogenesis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J41/00—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring
    • C07J41/0033—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005
    • C07J41/0055—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005 the 17-beta position being substituted by an uninterrupted chain of at least three carbon atoms which may or may not be branched, e.g. cholane or cholestane derivatives, optionally cyclised, e.g. 17-beta-phenyl or 17-beta-furyl derivatives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J41/00—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring
    • C07J41/0033—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005
    • C07J41/0094—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005 containing nitrile radicals, including thiocyanide radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J9/00—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of more than two carbon atoms, e.g. cholane, cholestane, coprostane

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Reproductive Health (AREA)
  • Endocrinology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Gynecology & Obstetrics (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Toxicology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pregnancy & Childbirth (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Steroid Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
CN00803662A 1999-02-10 2000-02-09 不饱和胆甾烷衍生物及其在制备调节减数分裂的药物中的应用 Pending CN1368977A (zh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP99250040.5 1999-02-10
EP99250040 1999-02-10

Publications (1)

Publication Number Publication Date
CN1368977A true CN1368977A (zh) 2002-09-11

Family

ID=8241140

Family Applications (1)

Application Number Title Priority Date Filing Date
CN00803662A Pending CN1368977A (zh) 1999-02-10 2000-02-09 不饱和胆甾烷衍生物及其在制备调节减数分裂的药物中的应用

Country Status (15)

Country Link
EP (1) EP1150993A1 (cs)
JP (1) JP2002536456A (cs)
KR (1) KR20010101820A (cs)
CN (1) CN1368977A (cs)
AU (1) AU3279700A (cs)
BR (1) BR0008065A (cs)
CA (1) CA2359687A1 (cs)
CZ (1) CZ20012866A3 (cs)
HU (1) HUP0200280A2 (cs)
IL (1) IL143735A0 (cs)
NO (1) NO20013901L (cs)
PL (1) PL350557A1 (cs)
SK (1) SK11382001A3 (cs)
WO (1) WO2000047604A1 (cs)
ZA (1) ZA200107387B (cs)

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5716777A (en) * 1994-06-23 1998-02-10 Novo Nordisk A/S Regulation of meiosis using sterols
HUP9800731A3 (en) * 1995-03-06 2000-03-28 Novo Nordisk As Stimulation of meiosis
CA2224866A1 (en) * 1995-06-23 1997-01-09 Novo Nordisk A/S Meiosis regulating compounds
JP2001506656A (ja) * 1996-12-20 2001-05-22 ノボ ノルディスク アクティーゼルスカブ 減数分裂調節化合物

Also Published As

Publication number Publication date
SK11382001A3 (sk) 2002-01-07
JP2002536456A (ja) 2002-10-29
ZA200107387B (en) 2002-12-06
KR20010101820A (ko) 2001-11-14
EP1150993A1 (en) 2001-11-07
WO2000047604A1 (en) 2000-08-17
AU3279700A (en) 2000-08-29
CZ20012866A3 (cs) 2002-01-16
NO20013901D0 (no) 2001-08-10
BR0008065A (pt) 2001-11-06
IL143735A0 (en) 2002-04-21
NO20013901L (no) 2001-08-10
PL350557A1 (en) 2002-12-16
HUP0200280A2 (hu) 2002-07-29
CA2359687A1 (en) 2000-08-17

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Legal Events

Date Code Title Description
C10 Entry into substantive examination
SE01 Entry into force of request for substantive examination
C06 Publication
PB01 Publication
C10 Entry into substantive examination
SE01 Entry into force of request for substantive examination
C02 Deemed withdrawal of patent application after publication (patent law 2001)
WD01 Invention patent application deemed withdrawn after publication