CN1387404A - 治疗肺病的方法和组合物 - Google Patents

治疗肺病的方法和组合物 Download PDF

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Publication number
CN1387404A
CN1387404A CN00815265A CN00815265A CN1387404A CN 1387404 A CN1387404 A CN 1387404A CN 00815265 A CN00815265 A CN 00815265A CN 00815265 A CN00815265 A CN 00815265A CN 1387404 A CN1387404 A CN 1387404A
Authority
CN
China
Prior art keywords
pde4
rolipram
administration
asthma
inhibitor
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN00815265A
Other languages
English (en)
Chinese (zh)
Inventor
彼得·N·古德费洛
理查德·尼曼
西奥多·J·托菲
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
SmithKline Beecham Corp
Original Assignee
SmithKline Beecham Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by SmithKline Beecham Corp filed Critical SmithKline Beecham Corp
Publication of CN1387404A publication Critical patent/CN1387404A/zh
Pending legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/575—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of three or more carbon atoms, e.g. cholane, cholestane, ergosterol, sitosterol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/58—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids containing heterocyclic rings, e.g. danazol, stanozolol, pancuronium or digitogenin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/06—Antiasthmatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pulmonology (AREA)
  • Epidemiology (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
CN00815265A 1999-11-02 2000-11-01 治疗肺病的方法和组合物 Pending CN1387404A (zh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US16315899P 1999-11-02 1999-11-02
US60/163,158 1999-11-02

Publications (1)

Publication Number Publication Date
CN1387404A true CN1387404A (zh) 2002-12-25

Family

ID=22588737

Family Applications (1)

Application Number Title Priority Date Filing Date
CN00815265A Pending CN1387404A (zh) 1999-11-02 2000-11-01 治疗肺病的方法和组合物

Country Status (29)

Country Link
EP (1) EP1225866A4 (fr)
JP (1) JP2003513028A (fr)
KR (1) KR20020057988A (fr)
CN (1) CN1387404A (fr)
AP (1) AP2002002496A0 (fr)
AR (1) AR029189A1 (fr)
AU (1) AU1357501A (fr)
BG (1) BG106748A (fr)
BR (1) BR0015270A (fr)
CA (1) CA2388333A1 (fr)
CO (1) CO5261512A1 (fr)
CZ (1) CZ20021512A3 (fr)
DZ (1) DZ3225A1 (fr)
EA (1) EA200200518A1 (fr)
EC (1) ECSP003747A (fr)
HK (1) HK1049107A1 (fr)
HU (1) HUP0203152A3 (fr)
IL (1) IL149367A0 (fr)
MA (1) MA26841A1 (fr)
MX (1) MXPA02004350A (fr)
NO (1) NO20022057L (fr)
OA (1) OA12076A (fr)
PE (1) PE20011005A1 (fr)
PL (1) PL355261A1 (fr)
SK (1) SK7592002A3 (fr)
TR (1) TR200201211T2 (fr)
TW (1) TWI242431B (fr)
WO (1) WO2001032127A2 (fr)
ZA (1) ZA200203435B (fr)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL160271A0 (en) 2001-09-19 2004-07-25 Altana Pharma Ag Pharmaceutical compositions containing pde4-inhibitors and nsaid
MXPA04003668A (es) * 2001-10-31 2004-07-22 Merck Patent Gmbh Inhibidores de fosfodiesteresa de tipo 4 y usos de los mismos.
UA82323C2 (uk) * 2002-08-09 2008-04-10 Меда Фарма Гмбх & Ко. Кг Нова комбінація глюкокортикоїду та pde-інгібітору для лікування респіраторних захворювань, алергічних захворювань, астми та хронічних обструктивних легеневих захворювань
TW200410923A (en) * 2002-10-17 2004-07-01 Ono Pharmaceutical Co Therapeutic agent for chronic obstructive pulmonary disease
CA2520577A1 (fr) * 2003-03-31 2004-10-14 Kyowa Hakko Kogyo Co., Ltd. Composition pharmaceutique
US20050026883A1 (en) * 2003-07-31 2005-02-03 Robinson Cynthia B. Combination of dehydroepiandrosterone or dehydroepiandrosterone-sulfate with a PDE-4 inhibitor for treatment of asthma or chronic obstructive pulmonary disease
JPWO2006041121A1 (ja) * 2004-10-13 2008-05-15 協和醗酵工業株式会社 慢性皮膚疾患の治療および／または予防剤
AU2006305620A1 (en) * 2005-10-19 2007-04-26 Ranbaxy Laboratories Limited Compositions of phosphodiesterase type IV inhibitors
CN102665807A (zh) 2010-01-05 2012-09-12 微剂量治疗技术公司 吸入设备和方法
WO2015063669A1 (fr) 2013-10-30 2015-05-07 Wockhardt Limited Compositions pharmaceutiques comprenant une combinaison de roflumilast et d'acébrophylline ou de leurs sels pharmaceutiquement acceptables

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PT710109E (pt) * 1993-06-18 2005-01-31 Smithkline Beecham Corp Metodo para identificar um inibidor de pde iv
DE4332041C2 (de) * 1993-09-21 1997-12-11 Rentschler Arzneimittel Verwendung von Pentoxifyllin bei bestimmten Lungenerkrankungen
PE44995A1 (es) * 1994-01-27 1995-12-18 Schering Corp Furoato de mometasona para el tratamiento de las enfermedades pulmonares y de las vias respiratorias
SE9801368D0 (sv) * 1998-04-20 1998-04-20 Astra Ab New use

Also Published As

Publication number Publication date
PE20011005A1 (es) 2001-09-28
ECSP003747A (es) 2002-05-23
SK7592002A3 (en) 2002-11-06
MA26841A1 (fr) 2004-12-20
TWI242431B (en) 2005-11-01
ZA200203435B (en) 2003-06-25
CA2388333A1 (fr) 2001-05-10
IL149367A0 (en) 2002-11-10
NO20022057L (no) 2002-06-27
HUP0203152A3 (en) 2004-06-28
AU1357501A (en) 2001-05-14
CZ20021512A3 (cs) 2003-04-16
HUP0203152A2 (hu) 2003-01-28
KR20020057988A (ko) 2002-07-12
JP2003513028A (ja) 2003-04-08
WO2001032127A3 (fr) 2001-12-06
CO5261512A1 (es) 2003-03-31
NO20022057D0 (no) 2002-04-30
DZ3225A1 (fr) 2001-05-10
OA12076A (en) 2006-05-04
BR0015270A (pt) 2002-06-18
EP1225866A4 (fr) 2004-04-21
BG106748A (en) 2003-02-28
EA200200518A1 (ru) 2002-10-31
AP2002002496A0 (en) 2002-06-30
PL355261A1 (en) 2004-04-05
AR029189A1 (es) 2003-06-18
EP1225866A2 (fr) 2002-07-31
TR200201211T2 (tr) 2002-08-21
MXPA02004350A (es) 2002-11-07
HK1049107A1 (zh) 2003-05-02
WO2001032127A2 (fr) 2001-05-10

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PB01 Publication
C10 Entry into substantive examination
SE01 Entry into force of request for substantive examination
C02 Deemed withdrawal of patent application after publication (patent law 2001)
WD01 Invention patent application deemed withdrawn after publication