CN1406277A - Prrsv的重组减毒 - Google Patents

Prrsv的重组减毒 Download PDF

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Publication number
CN1406277A
CN1406277A CN01804245A CN01804245A CN1406277A CN 1406277 A CN1406277 A CN 1406277A CN 01804245 A CN01804245 A CN 01804245A CN 01804245 A CN01804245 A CN 01804245A CN 1406277 A CN1406277 A CN 1406277A
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CN
China
Prior art keywords
amino acid
virus
prrs
orf1b
orf1a
Prior art date
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Pending
Application number
CN01804245A
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English (en)
Chinese (zh)
Inventor
克努特·埃尔伯斯
斯蒂芬·佩施
海克·伦格伯斯
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Boehringer Ingelheim Vetmedica GmbH
Original Assignee
Boehringer Ingelheim Vetmedica GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from DE2000103373 external-priority patent/DE10003373A1/de
Priority claimed from DE2000103371 external-priority patent/DE10003371A1/de
Priority claimed from DE2000103372 external-priority patent/DE10003372A1/de
Application filed by Boehringer Ingelheim Vetmedica GmbH filed Critical Boehringer Ingelheim Vetmedica GmbH
Publication of CN1406277A publication Critical patent/CN1406277A/zh
Pending legal-status Critical Current

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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N7/00—Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
    • C12N7/04—Inactivation or attenuation; Producing viral sub-units
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N7/00—Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/52—Bacterial cells; Fungal cells; Protozoal cells
    • A61K2039/522—Bacterial cells; Fungal cells; Protozoal cells avirulent or attenuated
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/525—Virus
    • A61K2039/5254—Virus avirulent or attenuated
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2770/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
    • C12N2770/00011—Details
    • C12N2770/10011—Arteriviridae
    • C12N2770/10022—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2770/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
    • C12N2770/00011—Details
    • C12N2770/10011—Arteriviridae
    • C12N2770/10061—Methods of inactivation or attenuation

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Virology (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • Immunology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Veterinary Medicine (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Surface Acoustic Wave Elements And Circuit Networks Thereof (AREA)
CN01804245A 2000-01-26 2001-01-26 Prrsv的重组减毒 Pending CN1406277A (zh)

Applications Claiming Priority (6)

Application Number Priority Date Filing Date Title
DE2000103373 DE10003373A1 (de) 2000-01-26 2000-01-26 Rekombinante Attenuation von PRRSV
DE2000103371 DE10003371A1 (de) 2000-01-26 2000-01-26 Rekombinante Attenuation von PRRSV
DE2000103372 DE10003372A1 (de) 2000-01-26 2000-01-26 Rekombinante Attenuation von PRRSV
DE10003372.5 2000-01-26
DE10003371.7 2000-01-26
DE10003373.3 2000-01-26

Publications (1)

Publication Number Publication Date
CN1406277A true CN1406277A (zh) 2003-03-26

Family

ID=27213605

Family Applications (1)

Application Number Title Priority Date Filing Date
CN01804245A Pending CN1406277A (zh) 2000-01-26 2001-01-26 Prrsv的重组减毒

Country Status (15)

Country Link
EP (1) EP1254213A2 (cs)
JP (1) JP2003520601A (cs)
KR (1) KR20030032910A (cs)
CN (1) CN1406277A (cs)
AR (1) AR027291A1 (cs)
AU (1) AU2001228502A1 (cs)
BR (1) BR0107827A (cs)
CA (1) CA2396454A1 (cs)
CZ (1) CZ20022554A3 (cs)
EA (1) EA200200743A1 (cs)
HU (1) HUP0204176A3 (cs)
MX (1) MXPA02007198A (cs)
PL (1) PL356274A1 (cs)
SK (1) SK10932002A3 (cs)
WO (1) WO2001055353A2 (cs)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2008110056A1 (en) * 2007-03-14 2008-09-18 China Animal Disease Control Center A vaccine for porcine reproductive and respiratory syndrome, a preparion method and use thereof
CN101307305B (zh) * 2008-04-30 2010-06-16 中国动物疫病预防控制中心 一种猪繁殖与呼吸综合征病毒弱毒株及免疫原性物质和疫苗

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2003129068A (ru) * 2001-03-09 2005-04-10 Бёрингер Ингельхайм Ветмедика Гмбх (De) Штаммы вируса репродуктивного и респираторного синдрома свиней (prrs) с ослабленной жизнеспособностью
US6841364B2 (en) * 2002-01-22 2005-01-11 Protatek International, Inc. Infectious cDNA clones of porcine reproductive and respiratory syndrome virus and expression vectors thereof
JP2007524363A (ja) 2003-03-27 2007-08-30 オタワ ヘルス リサーチ インスティチュート 変異体水疱性口内炎ウイルスおよびそれらの使用
RU2381035C2 (ru) * 2005-02-25 2010-02-10 Пфайзер Продактс Инк. Композиция для защиты свиней от инфекции ррсс-вируса (варианты) и вакцина, содержащая указанную композицию (варианты)
US7666585B2 (en) 2007-06-15 2010-02-23 Protatek International, Inc. Construction of chimera PRRSV, compositions and vaccine preparations
UA108902C2 (uk) * 2010-11-10 2015-06-25 Вірус північноамериканського репродуктивного та респіраторного синдрому свиней (prrs) та його застосування
US10072046B2 (en) * 2014-03-21 2018-09-11 Nutech Ventures Non-naturally occurring porcine reproductive and respiratory syndrome virus (PRRSV) and methods of using

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6251397B1 (en) * 1992-10-30 2001-06-26 Iowa State University Research Foundation, Inc. Proteins encoded by polynucleic acids isolated from a porcine reproductive and respiratory syndrome virus and immunogenic compositions containing the same
PT783321E (pt) * 1994-08-05 2006-08-31 Univ Minnesota Sequencia nucleotidica viral vr-2332 e metodos de utilizacao
EP0839912A1 (en) * 1996-10-30 1998-05-06 Instituut Voor Dierhouderij En Diergezondheid (Id-Dlo) Infectious clones of RNA viruses and vaccines and diagnostic assays derived thereof

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2008110056A1 (en) * 2007-03-14 2008-09-18 China Animal Disease Control Center A vaccine for porcine reproductive and respiratory syndrome, a preparion method and use thereof
CN100439494C (zh) * 2007-03-14 2008-12-03 中国动物疫病预防控制中心 猪繁殖与呼吸综合征疫苗、制备方法及应用
CN101307305B (zh) * 2008-04-30 2010-06-16 中国动物疫病预防控制中心 一种猪繁殖与呼吸综合征病毒弱毒株及免疫原性物质和疫苗

Also Published As

Publication number Publication date
BR0107827A (pt) 2002-11-05
EP1254213A2 (en) 2002-11-06
AR027291A1 (es) 2003-03-19
CA2396454A1 (en) 2001-08-02
KR20030032910A (ko) 2003-04-26
WO2001055353A2 (en) 2001-08-02
AU2001228502A1 (en) 2001-08-07
WO2001055353A3 (en) 2001-12-27
SK10932002A3 (sk) 2002-11-06
EA200200743A1 (ru) 2002-12-26
MXPA02007198A (es) 2002-12-09
PL356274A1 (en) 2004-06-28
JP2003520601A (ja) 2003-07-08
CZ20022554A3 (cs) 2002-10-16
HUP0204176A2 (hu) 2003-04-28
HUP0204176A3 (en) 2003-12-29

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