CN1668737A - 重组Bet.V.1过敏原突变体及其方法和制备 - Google Patents

重组Bet.V.1过敏原突变体及其方法和制备 Download PDF

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Publication number
CN1668737A
CN1668737A CNA038162849A CN03816284A CN1668737A CN 1668737 A CN1668737 A CN 1668737A CN A038162849 A CNA038162849 A CN A038162849A CN 03816284 A CN03816284 A CN 03816284A CN 1668737 A CN1668737 A CN 1668737A
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CN
China
Prior art keywords
group
betv1
allergen
recombinant
amino acid
Prior art date
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Pending
Application number
CNA038162849A
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English (en)
Chinese (zh)
Inventor
J·霍尔姆
M·弗雷拉斯
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ALK Abello AS
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ALK Abello AS
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Filing date
Publication date
Application filed by ALK Abello AS filed Critical ALK Abello AS
Publication of CN1668737A publication Critical patent/CN1668737A/zh
Pending legal-status Critical Current

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/415—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from plants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/53—DNA (RNA) vaccination
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Botany (AREA)
  • Immunology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pulmonology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
CNA038162849A 2002-05-16 2003-05-15 重组Bet.V.1过敏原突变体及其方法和制备 Pending CN1668737A (zh)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US38144002P 2002-05-16 2002-05-16
US60/381,440 2002-05-16
DKPA200200756 2002-05-16
DKPA200200756 2002-05-16

Publications (1)

Publication Number Publication Date
CN1668737A true CN1668737A (zh) 2005-09-14

Family

ID=29551230

Family Applications (1)

Application Number Title Priority Date Filing Date
CNA038162849A Pending CN1668737A (zh) 2002-05-16 2003-05-15 重组Bet.V.1过敏原突变体及其方法和制备

Country Status (6)

Country Link
EP (1) EP1504089A2 (pl)
CN (1) CN1668737A (pl)
AU (1) AU2003223934A1 (pl)
CA (1) CA2486112A1 (pl)
PL (1) PL212139B1 (pl)
WO (1) WO2003096869A2 (pl)

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103562388A (zh) * 2011-04-18 2014-02-05 国家技术研究中心Vtt 低过敏原
CN103649315A (zh) * 2011-04-18 2014-03-19 国家技术研究中心Vtt 低过敏原
CN111718912A (zh) * 2020-05-20 2020-09-29 华中农业大学 黄烷酮-3-羟化酶抗原表位肽及其抗体与应用

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK2116257T3 (da) 2000-08-09 2013-02-04 Alk Abello As Parenterale vaccineformuleringer og anvendelser deraf
WO2004047793A1 (en) 2002-11-26 2004-06-10 Alk-Abelló A/S Pharmaceutical allergen product
US8012505B2 (en) 2003-02-28 2011-09-06 Alk-Abello A/S Dosage form having a saccharide matrix
EP1599185A1 (en) 2003-02-28 2005-11-30 Alk-Abello A/S Dosage form having a saccharide matrix
RU2006126051A (ru) 2003-12-19 2008-01-27 Альк-Абелло А/С (Dk) Способы получения партии активного фармацевтического ингредиента, контейнер, содержащий криогранулы аллергенного продукта, и криогранула аллергенного продукта
US20060115499A1 (en) * 2004-09-27 2006-06-01 Alk-Abello A/S Liquid allergy vaccine formulation for oromucosal administration
WO2006050729A2 (en) * 2004-11-10 2006-05-18 Alk-Abellò A/S Method of preventive treatment of allergy by mucosal administration of an allergy vaccine
AU2006299310A1 (en) 2005-10-04 2007-04-12 Alk-Abello A/S Solid vaccine formulation
ITMI20052517A1 (it) * 2005-12-29 2007-06-30 Lofarma Spa Varianbtio ipoallergeniche dell'allergene maggiore bet v 1 di polline di betula verrucosa
FI20075059A0 (fi) 2007-01-29 2007-01-29 Valtion Teknillinen Allergeeniä sitovat monoklonaaliset IgE-vasta-aineet ja hypoallergeenit:tyypin l lgE:n ja allergeenin immunokompleksivuorovaikutus
CA2682054A1 (en) 2007-03-28 2008-10-02 Alk-Abello A/S Use of an adjuvanted allergy vaccine formulation for parenteral administration
EP2022507A1 (en) * 2007-08-07 2009-02-11 Universität Hamburg Antibody compositions specific for lgE, lgG4 and lgA epitopes as tools for the design of hypoallergenic molecules for specific immunotherapy
DE202008006598U1 (de) 2008-04-11 2008-10-02 Alk-Abelló A/S Allergie-Impfstoff-Formulierung zur mucosalen Verabreichung
WO2010146171A1 (en) 2009-06-19 2010-12-23 Alk-Abelló A/S Novel manner of administering allergen in allergen specific immunotherapy
ITMI20111489A1 (it) * 2011-08-03 2013-02-04 Lofarma Spa Varianti ipoallergeniche dell'allergene maggiore mal d 1 di malus domestica
EP2952200A1 (en) 2014-06-04 2015-12-09 Alk-Abelló A/S Allergen for prophylactic treatment of allergy

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FI932561L (fi) * 1990-12-05 1993-06-04 Novo Nordisk As Proteiner med foeraendrade epitoper och foerfaranden foer deras framstaellning
PL194804B1 (pl) * 1998-03-16 2007-07-31 Alk Abello As Zrekombinowany alergen, sposób przygotowywania zrekombinowanego alergenu, kompozycja farmaceutyczna oraz zastosowanie zrekombinowanego alergenu do przygotowywania leku do wywoływania odpowiedzi immunologicznej u osobnika i do przygotowywania leku do leczenia, zapobiegania lub osłabiania reakcji alergicznych
ES2220114T3 (es) * 1998-10-30 2004-12-01 Novozymes A/S Variantes de proteinas poco alergenicas.
AU3717600A (en) * 1999-03-02 2000-09-21 Board Of Trustees Of The University Of Arkansas, The Methods and reagents for decreasing clinical reaction to allergy
EP1280817A2 (en) * 2000-04-28 2003-02-05 Novozymes A/S Production and use of protein variants having modified immunogenecity
ATE414773T1 (de) * 2000-11-16 2008-12-15 Alk Abello As Mutante allergene
EP1453539B1 (en) * 2001-12-05 2008-11-19 Circassia Limited Immunotherapeutic methods and systems

Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103562388A (zh) * 2011-04-18 2014-02-05 国家技术研究中心Vtt 低过敏原
CN103649315A (zh) * 2011-04-18 2014-03-19 国家技术研究中心Vtt 低过敏原
CN103649315B (zh) * 2011-04-18 2016-12-07 德森特姆有限公司 低过敏原
CN111718912A (zh) * 2020-05-20 2020-09-29 华中农业大学 黄烷酮-3-羟化酶抗原表位肽及其抗体与应用
CN111718912B (zh) * 2020-05-20 2021-11-02 华中农业大学 黄烷酮-3-羟化酶抗原表位肽及其抗体与应用

Also Published As

Publication number Publication date
PL373086A1 (pl) 2005-08-08
PL212139B1 (pl) 2012-08-31
WO2003096869A2 (en) 2003-11-27
AU2003223934A1 (en) 2003-12-02
CA2486112A1 (en) 2003-11-27
WO2003096869A3 (en) 2004-04-29
AU2003223934A8 (en) 2003-12-02
EP1504089A2 (en) 2005-02-09

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