ATE414773T1 - Mutante allergene - Google Patents

Mutante allergene

Info

Publication number: ATE414773T1
Authority: AT; Austria
Prior art keywords: allergens; disclosed; naturally; mutant allergens; occurring
Prior art date: 2000-11-16

Application number

AT01996610T

Other languages

English (en)

Inventor

Jens Holm

Henrik Ipsen

Larsen Joergen Nedergaard

Michael Spangfort

Original Assignee

Alk Abello As

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2000-11-16

Filing date

2001-11-16

Publication date

2008-12-15

Family has litigation

First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=27222455&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ATE414773(T1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.

2001-11-16 Application filed by Alk Abello As filed Critical Alk Abello As

2008-12-15 Application granted granted Critical

2008-12-15 Publication of ATE414773T1 publication Critical patent/ATE414773T1/de

Links

Classifications

- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/43504—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from invertebrates
- C07K14/43563—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from invertebrates from insects
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/415—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from plants
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/43504—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from invertebrates
- C07K14/43563—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from invertebrates from insects
- C07K14/43568—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from invertebrates from insects from wasps
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/43504—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from invertebrates
- C07K14/43563—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from invertebrates from insects
- C07K14/43572—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from invertebrates from insects from bees
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
- C07K16/16—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from plants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/57—Medicinal preparations containing antigens or antibodies characterised by the type of response, e.g. Th1, Th2
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2299/00—Coordinates from 3D structures of peptides, e.g. proteins or enzymes

Landscapes

Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Genetics & Genomics (AREA)
Zoology (AREA)
General Health & Medical Sciences (AREA)
Medicinal Chemistry (AREA)
Engineering & Computer Science (AREA)
Molecular Biology (AREA)
Biochemistry (AREA)
Biophysics (AREA)
Bioinformatics & Cheminformatics (AREA)
Insects & Arthropods (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Immunology (AREA)
Gastroenterology & Hepatology (AREA)
Toxicology (AREA)
Tropical Medicine & Parasitology (AREA)
Biomedical Technology (AREA)
Veterinary Medicine (AREA)
Pharmacology & Pharmacy (AREA)
General Engineering & Computer Science (AREA)
Public Health (AREA)
Wood Science & Technology (AREA)
Botany (AREA)
Biotechnology (AREA)
Animal Behavior & Ethology (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Transplantation (AREA)
Microbiology (AREA)
Physics & Mathematics (AREA)
Pulmonology (AREA)
Plant Pathology (AREA)
Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Peptides Or Proteins (AREA)
Micro-Organisms Or Cultivation Processes Thereof (AREA)
Medicines Containing Material From Animals Or Micro-Organisms (AREA)

AT01996610T 2000-11-16 2001-11-16 Mutante allergene ATE414773T1 (de)

Applications Claiming Priority (3)

Application Number	Priority Date	Filing Date
US24936100P	2000-11-16	2000-11-16
DKPA200001718		2000-11-16
US29817001P	2001-06-14	2001-06-14

Publications (1)

Publication Number	Publication Date
ATE414773T1 true ATE414773T1 (de)	2008-12-15

Family

ID=27222455

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT01996610T ATE414773T1 (de)	2000-11-16	2001-11-16	Mutante allergene

Country Status (17)

Country	Link
EP (1)	EP1373510B1 (de)
JP (1)	JP2004521618A (de)
KR (1)	KR100919914B1 (de)
CN (1)	CN100577804C (de)
AT (1)	ATE414773T1 (de)
AU (2)	AU2350502A (de)
CA (1)	CA2429172C (de)
CZ (1)	CZ20031653A3 (de)
DE (1)	DE60136653D1 (de)
DK (1)	DK1373510T3 (de)
ES (1)	ES2317955T3 (de)
HU (1)	HUP0302601A3 (de)
MX (1)	MXPA03004174A (de)
NO (1)	NO329721B1 (de)
NZ (1)	NZ525820A (de)
PL (1)	PL214225B1 (de)
WO (1)	WO2002040676A2 (de)

Families Citing this family (42)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DK2116257T3 (da)	2000-08-09	2013-02-04	Alk Abello As	Parenterale vaccineformuleringer og anvendelser deraf
CN1668737A (zh) *	2002-05-16	2005-09-14	阿尔克-阿贝洛有限公司	重组Bet.V.1过敏原突变体及其方法和制备
FR2841906B1 (fr) *	2002-07-05	2006-08-18	Stallergenes Sa	Molecule d'acide nucleique codant une preproproteine d'allergene d'un acarien du genre dermatophagoides ou euroglyphus et son utilisation pour la production dudit allergene dans les plantes
CA2503886A1 (en) *	2002-11-01	2004-05-13	Alk-Abello A/S	Recombinant protein variants
WO2004047793A1 (en)	2002-11-26	2004-06-10	Alk-Abelló A/S	Pharmaceutical allergen product
EP1599185A1 (de)	2003-02-28	2005-11-30	Alk-Abello A/S	Dosierungsform auf basis von einer saccharid-matrix
US8012505B2 (en)	2003-02-28	2011-09-06	Alk-Abello A/S	Dosage form having a saccharide matrix
EP2287180B9 (de) *	2003-06-04	2013-11-06	Merck Patent GmbH	Lol p 5-Derivate mit reduzierter Allergenität und erhaltener T-Zellreaktivität
ES2363342T3 (es) *	2003-12-19	2011-08-01	Alk-Abelló A/S	Procedimiento para criogranulación y almacenamiento de alérgenos.
RU2006126051A (ru)	2003-12-19	2008-01-27	Альк-Абелло А/С (Dk)	Способы получения партии активного фармацевтического ингредиента, контейнер, содержащий криогранулы аллергенного продукта, и криогранула аллергенного продукта
WO2005103082A2 (en) *	2004-04-23	2005-11-03	Novozymes A/S	Group 1 mite polypeptide variants
US20060115499A1 (en) *	2004-09-27	2006-06-01	Alk-Abello A/S	Liquid allergy vaccine formulation for oromucosal administration
US20060121063A1 (en) *	2004-10-22	2006-06-08	Novozymes A/S	Group 2 mite polypeptide variants
ZA200707413B (en)	2005-03-18	2009-01-28	Cytos Biotechnology Ag	Cat allergen fusion proteins and uses thereof
AU2006299310A1 (en)	2005-10-04	2007-04-12	Alk-Abello A/S	Solid vaccine formulation
EP1814516B1 (de) *	2005-11-04	2012-12-26	Alk-Abelló A/S	Verwendung einer formulierung eines flüssigen allergieimpfstoffs zur verabreichung über die mundschleimhaut
CN103933562A (zh) *	2005-11-04	2014-07-23	爱尔开-阿贝优公司	用于口腔粘膜给药的液体变态反应性疫苗制剂的用途
ITMI20052517A1 (it) *	2005-12-29	2007-06-30	Lofarma Spa	Varianbtio ipoallergeniche dell'allergene maggiore bet v 1 di polline di betula verrucosa
AT503297B1 (de) *	2006-05-18	2007-09-15	Biomay Ag	Allergen-spezifische antikörper
AT503690A1 (de)	2006-06-09	2007-12-15	Biomay Ag	Hypoallergene moleküle
EP1908777B1 (de) *	2006-10-06	2016-02-03	Stallergenes	Milbenfusionsproteine
CA2682054A1 (en)	2007-03-28	2008-10-02	Alk-Abello A/S	Use of an adjuvanted allergy vaccine formulation for parenteral administration
NZ583362A (en) *	2007-08-15	2012-06-29	Circassia Ltd	Peptide with reduced dimer formation
DE202008006598U1 (de)	2008-04-11	2008-10-02	Alk-Abelló A/S	Allergie-Impfstoff-Formulierung zur mucosalen Verabreichung
WO2010146171A1 (en)	2009-06-19	2010-12-23	Alk-Abelló A/S	Novel manner of administering allergen in allergen specific immunotherapy
EP2523685A1 (de) *	2010-01-14	2012-11-21	Merck Patent GmbH	VARIANTEN DER GRUPPE 5-ALLERGENE DER SÜßGRÄSER MIT REDUZIERTER ALLERGENITÄT DURCH MUTAGENESE VON PROLINRESTEN
EP2388268A1 (de) *	2010-05-18	2011-11-23	Stallergenes S.A.	Rekombinantes, in Pichia pastoris als natürliches Allergen exprimiertes Der-p-2 zur Immuntherapie und für Diagnosezwecke
FI20115374A0 (fi)	2011-04-18	2011-04-18	Teknologian Tutkimuskeskus Vtt Oy	Uudet hypoallergeenit
FI20115375A0 (fi)	2011-04-18	2011-04-18	Teknologian Tutkimuskeskus Vtt Oy	Uudet hypoallergeenit
ITMI20112301A1 (it)	2011-12-19	2013-06-20	Lofarma Spa	Varianti ipoallergeniche dell'allergene maggiore phl p 5 di phleum pratense
EP2692732A1 (de)	2012-08-03	2014-02-05	Stallergenes S.A.	Neues Allergen aus Kreuzkrautpollen und Verwendung davon
PL2914286T3 (pl)	2012-10-30	2022-01-31	Aravax Pty Ltd	Nowe cząsteczki immunoterapeutyczne oraz ich zastosowania
CA2914037A1 (en) *	2013-06-06	2014-12-11	Anergis S.A.	Contiguous overlapping peptides for treatment of house dust mites allergy
EP3050040A2 (de)	2013-09-24	2016-08-03	Fibar Group S.A.	Intelligenter rauchmelder
WO2015042664A1 (en)	2013-09-25	2015-04-02	Monash University	Novel immunotherapeutic composition and uses thereof
EP2952200A1 (de)	2014-06-04	2015-12-09	Alk-Abelló A/S	Allergen zur vorbeugenden Behandlung von Allergien
US9898175B2 (en)	2014-08-05	2018-02-20	Fibar Group S.A.	Home network manager for home automation
EP3269730A1 (de) *	2016-07-12	2018-01-17	Universität Salzburg	Allergenvarianten
CN110621773B (zh)	2017-05-19	2023-06-09	豪夫迈·罗氏有限公司	用于产生胸腺细胞上清液的方法
CN110093336B (zh) *	2018-01-29	2023-03-24	上海雅心生物技术有限公司	一种稳定的胰蛋白酶及其制备方法
RU2761431C9 (ru)	2020-10-26	2022-04-18	Федеральное государственное бюджетное учреждение "Государственный научный центр "Институт иммунологии" Федерального медико-биологического агентства России (ФГБУ "ГНЦ Институт иммунологии" ФМБА России)	Рекомбинантный полипептид на основе аллергена пыльцы березы и аллергена яблока в качестве вакцины от аллергии
EP4539877A1 (de) *	2022-06-17	2025-04-23	Danmarks Tekniske Universitet	Allergieimpfstoffe auf basis von konsensallergenen

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
WO1997030150A2 (en) *	1996-02-15	1997-08-21	Pangenetics B.V.	Molecules for the induction of immunological tolerance
DE19713001A1 (de) *	1997-03-27	1998-10-01	Merck Patent Gmbh	Graminaenpollenallergenmutanten zur spezifischen Immuntherapie, deren Herstellung und Verwendung
AU743647B2 (en) *	1998-01-31	2002-01-31	Mt. Sinai School Of Medicine Of New York University	Methods and reagents for decreasing allergic reactions
PL194804B1 (pl) *	1998-03-16	2007-07-31	Alk Abello As	Zrekombinowany alergen, sposób przygotowywania zrekombinowanego alergenu, kompozycja farmaceutyczna oraz zastosowanie zrekombinowanego alergenu do przygotowywania leku do wywoływania odpowiedzi immunologicznej u osobnika i do przygotowywania leku do leczenia, zapobiegania lub osłabiania reakcji alergicznych

2001
- 2001-11-16 AT AT01996610T patent/ATE414773T1/de active
- 2001-11-16 CA CA2429172A patent/CA2429172C/en not_active Expired - Fee Related
- 2001-11-16 MX MXPA03004174A patent/MXPA03004174A/es active IP Right Grant
- 2001-11-16 DE DE60136653T patent/DE60136653D1/de not_active Expired - Lifetime
- 2001-11-16 AU AU2350502A patent/AU2350502A/xx active Pending
- 2001-11-16 AU AU2002223505A patent/AU2002223505B2/en not_active Ceased
- 2001-11-16 EP EP01996610A patent/EP1373510B1/de not_active Expired - Lifetime
- 2001-11-16 HU HU0302601A patent/HUP0302601A3/hu unknown
- 2001-11-16 JP JP2002543671A patent/JP2004521618A/ja active Pending
- 2001-11-16 CN CN01820783A patent/CN100577804C/zh not_active Expired - Fee Related
- 2001-11-16 PL PL362273A patent/PL214225B1/pl not_active IP Right Cessation
- 2001-11-16 NZ NZ525820A patent/NZ525820A/en not_active IP Right Cessation
- 2001-11-16 DK DK01996610T patent/DK1373510T3/da active
- 2001-11-16 KR KR1020037006644A patent/KR100919914B1/ko not_active Expired - Fee Related
- 2001-11-16 WO PCT/DK2001/000764 patent/WO2002040676A2/en not_active Ceased
- 2001-11-16 ES ES01996610T patent/ES2317955T3/es not_active Expired - Lifetime
- 2001-11-16 CZ CZ20031653A patent/CZ20031653A3/cs unknown
2003
- 2003-05-15 NO NO20032213A patent/NO329721B1/no not_active IP Right Cessation

Also Published As

Publication number	Publication date
KR20030076577A (ko)	2003-09-26
MXPA03004174A (es)	2004-12-02
WO2002040676A3 (en)	2003-10-09
JP2004521618A (ja)	2004-07-22
ES2317955T3 (es)	2009-05-01
WO2002040676A2 (en)	2002-05-23
PL214225B1 (pl)	2013-07-31
AU2350502A (en)	2002-05-27
CN1484699A (zh)	2004-03-24
HUP0302601A2 (hu)	2003-11-28
AU2002223505B2 (en)	2006-12-07
NO20032213D0 (no)	2003-05-15
EP1373510B1 (de)	2008-11-19
CA2429172A1 (en)	2002-05-23
EP1373510A2 (de)	2004-01-02
NO329721B1 (no)	2010-12-06
PL362273A1 (en)	2004-10-18
DK1373510T3 (da)	2009-02-23
NO20032213L (no)	2003-07-02
DE60136653D1 (de)	2009-01-02
CA2429172C (en)	2012-03-20
NZ525820A (en)	2005-01-28
CZ20031653A3 (en)	2004-03-17
KR100919914B1 (ko)	2009-10-06
HUP0302601A3 (en)	2010-01-28
HK1060371A1 (en)	2004-08-06
CN100577804C (zh)	2010-01-06

Legal Events

Date

Code

Title

Description

2009-07-15

UEP

Publication of translation of european patent specification

Ref document number: 1373510

Country of ref document: EP

Publication	Publication Date	Title
ATE414773T1 (de)	2008-12-15	Mutante allergene
NO20004614D0 (no)	2000-09-15	Mutante rekombinante allergener
DE69529219D1 (en)	2003-01-30	Helicobacter proteine und impstoffe
AU2001277961A1 (en)	2002-02-18	Compositions comprising heat shock proteins or alpha(2)macroglobulin, antigenic molecules and saponins, and methods of use thereof
PL364138A1 (en)	2004-12-13	Proteins producing an altered immunogenic response and methods of making and using the same
DE69534875D1 (de)	2006-05-11	Kalziumfreie subtilisin mutanten
EP0757717A4 (de)	1998-04-15	Papillomavirus vakzine
BG101132A (en)	1998-04-30	Pyridoanilated thienyl and furanyl oxazolidinons
ATE452195T1 (de)	2010-01-15	Protease mutanten mit reduzierter allergener wirkung in menschen und methoden zur konstruktion,identifizierung und herstellung dieser proteasen
MXPA01007710A (es)	2003-06-24	Agente de secado por congelacion que contiene paramilon, su produccion y uso.
MXPA02004666A (es)	2003-06-24	Gelatinas recombinantes.
AU2001253456A1 (en)	2001-10-30	Antithrombogenic membrane mimetic compositions and methods
BG103914A (en)	2000-07-31	Maintained separation of delayed gels
WO2003096869A3 (en)	2004-04-29	Recombinant bet. v. 1. allergen mutants, methods and process thereof
BG102891A (en)	1999-09-30	Enzymic pregranulate for fodder granulate
TNSN97130A1 (fr)	2005-03-15	Variants de l'aprotinine presentant des proprietes ameliorees
AP9901666A0 (en)	1999-12-31	Leishmania vaccine.
EP0957936A4 (de)	2001-09-12	Zusammensetzungen von rekombinanten papillomavirus vakzinen
SE9602822D0 (sv)	1996-07-19	New receptor
WO2002094992A3 (en)	2004-02-26	Directed evolution of protein in mammalian cells
EP0945510A4 (de)	2002-07-24	Zum genus bacillus gehörender stamm und insektizide proteine
GB2374871A (en)	2002-10-30	Peptide fragments of colostrinin and their use
EP0811695A3 (de)	1998-07-29	Mutierte S182(PS-1) Gene
WO2000027881A3 (de)	2000-08-03	Menschliche interleukin -10 mutantenproteine
WO2002067982A3 (en)	2004-02-26	Mycobacterial vaccines