CR10080A - Preparacion de gamma-aminoacidos que tienen afinidad por la proteina alfa-2-delta - Google Patents

Preparacion de gamma-aminoacidos que tienen afinidad por la proteina alfa-2-delta

Info

Publication number
CR10080A
CR10080A CR10080A CR10080A CR10080A CR 10080 A CR10080 A CR 10080A CR 10080 A CR10080 A CR 10080A CR 10080 A CR10080 A CR 10080A CR 10080 A CR10080 A CR 10080A
Authority
CR
Costa Rica
Prior art keywords
amino acids
alfa
gamma
affinity
preparation
Prior art date
Application number
CR10080A
Other languages
English (en)
Inventor
Claire Evans Margaret
Charles Franklin Llyod
Michelle Murtagh Lorraine
Norman Nanninga Thomas
Allen Pearlman Bruce
Edward Saenz James
Josephine Willis Niamh
Original Assignee
Pfizer Prod Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer Prod Inc filed Critical Pfizer Prod Inc
Publication of CR10080A publication Critical patent/CR10080A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C227/00—Preparation of compounds containing amino and carboxyl groups bound to the same carbon skeleton
    • C07C227/30—Preparation of optical isomers
    • C07C227/32—Preparation of optical isomers by stereospecific synthesis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C227/00—Preparation of compounds containing amino and carboxyl groups bound to the same carbon skeleton
    • C07C227/04—Formation of amino groups in compounds containing carboxyl groups
    • C07C227/06—Formation of amino groups in compounds containing carboxyl groups by addition or substitution reactions, without increasing the number of carbon atoms in the carbon skeleton of the acid
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C229/00—Compounds containing amino and carboxyl groups bound to the same carbon skeleton
    • C07C229/02—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton
    • C07C229/04—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated
    • C07C229/06—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having only one amino and one carboxyl group bound to the carbon skeleton
    • C07C229/08—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having only one amino and one carboxyl group bound to the carbon skeleton the nitrogen atom of the amino group being further bound to hydrogen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C253/00—Preparation of carboxylic acid nitriles
    • C07C253/30—Preparation of carboxylic acid nitriles by reactions not involving the formation of cyano groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C255/00—Carboxylic acid nitriles
    • C07C255/01—Carboxylic acid nitriles having cyano groups bound to acyclic carbon atoms
    • C07C255/19—Carboxylic acid nitriles having cyano groups bound to acyclic carbon atoms containing cyano groups and carboxyl groups, other than cyano groups, bound to the same saturated acyclic carbon skeleton
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P13/00—Preparation of nitrogen-containing organic compounds
    • C12P13/002—Nitriles (-CN)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P13/00—Preparation of nitrogen-containing organic compounds
    • C12P13/005—Amino acids other than alpha- or beta amino acids, e.g. gamma amino acids
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P41/00—Processes using enzymes or microorganisms to separate optical isomers from a racemic mixture
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P41/00—Processes using enzymes or microorganisms to separate optical isomers from a racemic mixture
    • C12P41/003—Processes using enzymes or microorganisms to separate optical isomers from a racemic mixture by ester formation, lactone formation or the inverse reactions
    • C12P41/005—Processes using enzymes or microorganisms to separate optical isomers from a racemic mixture by ester formation, lactone formation or the inverse reactions by esterification of carboxylic acid groups in the enantiomers or the inverse reaction
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/582—Recycling of unreacted starting or intermediate materials

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • Microbiology (AREA)
  • Analytical Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pyrrole Compounds (AREA)

Abstract

Se dan a conocer materiales y procedimientos para preparar y - aminoácidos opticamente activos de fórmula 1 que se unen a la subunidad alfa-2-delta (a2o) de un canal de calcio.
CR10080A 2005-12-21 2008-06-18 Preparacion de gamma-aminoacidos que tienen afinidad por la proteina alfa-2-delta CR10080A (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US75283905P 2005-12-21 2005-12-21

Publications (1)

Publication Number Publication Date
CR10080A true CR10080A (es) 2008-07-10

Family

ID=37903526

Family Applications (1)

Application Number Title Priority Date Filing Date
CR10080A CR10080A (es) 2005-12-21 2008-06-18 Preparacion de gamma-aminoacidos que tienen afinidad por la proteina alfa-2-delta

Country Status (28)

Country Link
US (2) US20070141684A1 (es)
EP (2) EP2017259A3 (es)
JP (1) JP2009520492A (es)
KR (1) KR20080068932A (es)
CN (1) CN101341117A (es)
AP (1) AP2008004485A0 (es)
AR (1) AR058559A1 (es)
AU (1) AU2006327872A1 (es)
BR (1) BRPI0620467A2 (es)
CA (1) CA2633358A1 (es)
CR (1) CR10080A (es)
DO (1) DOP2006000286A (es)
EA (1) EA200801393A1 (es)
EC (1) ECSP088551A (es)
GT (1) GT200600524A (es)
IL (1) IL191840A0 (es)
MA (1) MA30139B1 (es)
ME (1) ME00005B (es)
NL (1) NL2000374C2 (es)
NO (1) NO20082989L (es)
NZ (1) NZ568971A (es)
PE (1) PE20071169A1 (es)
RS (1) RS20080279A (es)
TN (1) TNSN08272A1 (es)
TW (1) TW200736201A (es)
UY (1) UY30031A1 (es)
WO (1) WO2007072159A1 (es)
ZA (1) ZA200804780B (es)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EA019285B1 (ru) * 2008-05-21 2014-02-28 Сандоз Аг Способ стереоселективного ферментативного гидролиза эфира 5-метил-3-нитрометилгексановой кислоты
CN103003264B (zh) 2010-05-21 2014-08-06 切米利亚股份公司 嘧啶衍生物
FR2966734B1 (fr) * 2010-10-29 2014-07-18 Max Rombi Composition comprenant au moins une enzyme proteolytique pour son utilisation pour empecher la synthese des triglycerides
CA2830129C (en) 2011-03-24 2016-07-19 Chemilia Ab Novel pyrimidine derivatives
CN102249833B (zh) * 2011-05-27 2013-12-11 中国科学院化学研究所 一种制备手性γ-氨基酸及其衍生物的方法
WO2017155025A1 (ja) * 2016-03-10 2017-09-14 第一三共株式会社 酵素による光学分割を用いた光学活性吉草酸誘導体の製造方法
CN108192932B (zh) * 2017-12-26 2020-09-29 上海皓元生物医药科技有限公司 一种手性醇的酶催化制备方法
CN112877219A (zh) * 2021-01-29 2021-06-01 江西科技师范大学 一种高浓度胆固醇培养基及其制备方法和应用
CN119462461B (zh) * 2024-12-06 2025-11-04 万华化学集团股份有限公司 一种维生素a异构化的方法

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5376645A (en) 1990-01-23 1994-12-27 University Of Kansas Derivatives of cyclodextrins exhibiting enhanced aqueous solubility and the use thereof
KR0166088B1 (ko) 1990-01-23 1999-01-15 . 수용해도가 증가된 시클로덱스트린 유도체 및 이의 용도
US5618710A (en) 1990-08-03 1997-04-08 Vertex Pharmaceuticals, Inc. Crosslinked enzyme crystals
GB9518953D0 (en) 1995-09-15 1995-11-15 Pfizer Ltd Pharmaceutical formulations
WO2000035298A1 (en) 1996-11-27 2000-06-22 Wm. Wrigley Jr. Company Chewing gum containing medicament active agents
GB9711643D0 (en) 1997-06-05 1997-07-30 Janssen Pharmaceutica Nv Glass thermoplastic systems
JP3904452B2 (ja) * 1999-06-10 2007-04-11 ワーナー−ランバート カンパニー リミテッド ライアビリティー カンパニー モノ−およびジ置換３−プロピルガンマ−アミノ酪酸
US6642398B2 (en) * 1999-06-10 2003-11-04 Warner-Lambert Company Mono-and disubstituted 3-propyl gamma-aminobutyric acids
KR20050085636A (ko) 2002-12-13 2005-08-29 워너-램버트 캄파니 엘엘씨 섬유근육통 및 기타 질환의 치료를 위한 프레가발린 유도체
UA82292C2 (uk) * 2004-04-14 2008-03-25 Пфайзер Продактс Инк. Спосіб стереоселективного біоперетворення аліфатичних динітрилів в ціанокарбонові кислоти (варіанти)

Also Published As

Publication number Publication date
CA2633358A1 (en) 2007-06-28
NL2000374C2 (nl) 2010-02-09
PE20071169A1 (es) 2007-11-30
GT200600524A (es) 2007-12-03
ZA200804780B (en) 2009-05-27
NO20082989L (no) 2008-09-19
WO2007072159A1 (en) 2007-06-28
TW200736201A (en) 2007-10-01
EP1973867A1 (en) 2008-10-01
JP2009520492A (ja) 2009-05-28
ECSP088551A (es) 2008-07-30
CN101341117A (zh) 2009-01-07
EP2017259A3 (en) 2011-04-13
KR20080068932A (ko) 2008-07-24
EA200801393A1 (ru) 2009-12-30
ME00005B (me) 2010-06-10
US20090299093A1 (en) 2009-12-03
NL2000374A1 (nl) 2007-06-25
US20070141684A1 (en) 2007-06-21
NZ568971A (en) 2010-04-30
WO2007072159B1 (en) 2008-08-21
AR058559A1 (es) 2008-02-13
TNSN08272A1 (fr) 2009-10-30
IL191840A0 (en) 2008-12-29
DOP2006000286A (es) 2007-07-31
EP2017259A2 (en) 2009-01-21
AU2006327872A1 (en) 2007-06-28
MA30139B1 (fr) 2009-01-02
AP2008004485A0 (en) 2008-06-30
MEP0708A (xx) 2010-02-10
BRPI0620467A2 (pt) 2011-11-16
UY30031A1 (es) 2007-07-31
RS20080279A (sr) 2009-07-15

Similar Documents

Publication Publication Date Title
CR10080A (es) Preparacion de gamma-aminoacidos que tienen afinidad por la proteina alfa-2-delta
EA200802170A1 (ru) Лиофилизированная композиция терапевтического пептидного антитела
MY169272A (en) Her2 antibody composition
AR107785A2 (es) Composiciones estabilizadas de proteínas que tienen un radical tiol libre
EA200870599A1 (ru) Стабильные препараты лаквинимода
ECSP045319A (es) AMINOÁCIDOS CON AFINIDAD POR LA PROTEINA a2d
ATE491349T1 (de) Neue nutrazeutika-zusammensetzungen
EA200970376A1 (ru) Peg-илированный паратиреоидный гормон в качестве модулятора рецептора паратиреоидного гормона и его применение
ATE552832T1 (de) Antidepressivum-propharmaka
ECSP066450A (es) AMINOACIDOS CON AFINIDAD POR LA PROTEINA a2d
BRPI0414798A (pt) métodos para usar aminoácidos com afinidade para a proteìna alfa2delta
HN2003000108A (es) AMINOACIDOS CON AFINIDAD POR LA PROTEINA a2o´
BRPI0513028A (pt) preparação de beta-aminoácidos tendo afinidade para a proteìna alfa-2-delta
UY29033A1 (es) Aminoácidos con afinidad por la proteína a2o (alfa 2 delta)
NO20065643L (no) Fremstilling av beta-aminosyrer som har affinitet for proteinet alfa-2-delta
DOP2004001000A (es) Aminoacidos con afinidad por la proteina
GT200500267A (es) Uso de epotilonas en el tratamiento de metastasis en hueso
BRPI0503222A (pt) Formulações orais de paricalcitol
DOP2003000616A (es) Aminoacidos con afinidad por la proteina a2
CR7618A (es) Metodos de tratamiento con inhibidores de la ptec y agentes antihipertensivos

Legal Events

Date Code Title Description
FA Abandonment or withdrawal (granting procedure)