ATE552832T1 - Antidepressivum-propharmaka - Google Patents
Antidepressivum-propharmakaInfo
- Publication number
- ATE552832T1 ATE552832T1 AT07751499T AT07751499T ATE552832T1 AT E552832 T1 ATE552832 T1 AT E552832T1 AT 07751499 T AT07751499 T AT 07751499T AT 07751499 T AT07751499 T AT 07751499T AT E552832 T1 ATE552832 T1 AT E552832T1
- Authority
- AT
- Austria
- Prior art keywords
- antidepressant
- propharmacies
- prodrugs
- prodrug
- conjugated
- Prior art date
Links
- 230000001430 anti-depressive effect Effects 0.000 title abstract 4
- 239000000935 antidepressant agent Substances 0.000 title abstract 4
- 229940005513 antidepressants Drugs 0.000 title abstract 4
- 239000000651 prodrug Substances 0.000 abstract 2
- 229940002612 prodrug Drugs 0.000 abstract 2
- 150000001413 amino acids Chemical class 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
- A61K47/54—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic compound
- A61K47/542—Carboxylic acids, e.g. a fatty acid or an amino acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
- A61K47/62—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being a protein, peptide or polyamino acid
- A61K47/64—Drug-peptide, drug-protein or drug-polyamino acid conjugates, i.e. the modifying agent being a peptide, protein or polyamino acid which is covalently bonded or complexed to a therapeutically active agent
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Epidemiology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Neurology (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Neurosurgery (AREA)
- Biomedical Technology (AREA)
- Molecular Biology (AREA)
- Psychiatry (AREA)
- Pain & Pain Management (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US77621606P | 2006-02-24 | 2006-02-24 | |
| PCT/US2007/004743 WO2007100668A2 (en) | 2006-02-24 | 2007-02-22 | Antidepressant prodrugs |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE552832T1 true ATE552832T1 (de) | 2012-04-15 |
Family
ID=38459574
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT07751499T ATE552832T1 (de) | 2006-02-24 | 2007-02-22 | Antidepressivum-propharmaka |
Country Status (5)
| Country | Link |
|---|---|
| US (1) | US20110136742A1 (de) |
| EP (1) | EP1991248B1 (de) |
| AT (1) | ATE552832T1 (de) |
| CA (1) | CA2643892A1 (de) |
| WO (1) | WO2007100668A2 (de) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US8198268B2 (en) | 2008-10-31 | 2012-06-12 | Janssen Biotech, Inc. | Tianeptine sulfate salt forms and methods of making and using the same |
| MY162437A (en) * | 2014-06-27 | 2017-06-15 | Kao Corp | Solid composition |
| US10369134B2 (en) | 2017-12-05 | 2019-08-06 | Sunovion Pharmaceuticals Inc. | Nonracemic mixtures and uses thereof |
| MX2020005517A (es) | 2017-12-05 | 2020-11-09 | Sunovion Pharmaceuticals Inc | Formas cristalinas y metodos de produccion de las mismas. |
| WO2020247627A1 (en) | 2019-06-04 | 2020-12-10 | Sunovion Pharmaceuticals Inc. | Modified release formulations and uses thereof |
| CN116999403A (zh) * | 2022-04-29 | 2023-11-07 | 深圳埃格林医药有限公司 | 地昔帕明类似物及其口服胶囊制剂 |
| KR20250034266A (ko) * | 2023-09-01 | 2025-03-11 | 환인제약 주식회사 | 설트랄린 또는 이의 염을 포함하는 약학적 조성물 |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3875137A (en) * | 1973-04-20 | 1975-04-01 | Searle & Co | N-Substituted aspactyl peptide amids |
| DE69528773T2 (de) * | 1994-10-05 | 2003-09-04 | Cari Loder | Behandlung von multipler sklerose (ms) und anderen demyelinisationserkrankungen unter verwendung von lofepramin in kombination mit l-phenylalamin, tyrosin oder tryptophan und evtl. einer vitamin b12-verbindung |
| US6716452B1 (en) | 2000-08-22 | 2004-04-06 | New River Pharmaceuticals Inc. | Active agent delivery systems and methods for protecting and administering active agents |
| US7060708B2 (en) | 1999-03-10 | 2006-06-13 | New River Pharmaceuticals Inc. | Active agent delivery systems and methods for protecting and administering active agents |
| WO2005032474A2 (en) * | 2003-09-30 | 2005-04-14 | New River Pharmaceuticals Inc. | Pharmaceutical compositions for prevention of overdose or abuse |
| KR20050010756A (ko) | 2002-02-22 | 2005-01-28 | 뉴 리버 파마슈티칼스, 인크. | 피험자 간 약물 혈청 농도의 변동성을 감소시키기 위한펩티드-약물 접합체의 용도 |
-
2007
- 2007-02-22 US US12/280,190 patent/US20110136742A1/en not_active Abandoned
- 2007-02-22 WO PCT/US2007/004743 patent/WO2007100668A2/en not_active Ceased
- 2007-02-22 AT AT07751499T patent/ATE552832T1/de active
- 2007-02-22 EP EP07751499A patent/EP1991248B1/de not_active Not-in-force
- 2007-02-22 CA CA002643892A patent/CA2643892A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| EP1991248A2 (de) | 2008-11-19 |
| WO2007100668A2 (en) | 2007-09-07 |
| WO2007100668A3 (en) | 2008-09-12 |
| US20110136742A1 (en) | 2011-06-09 |
| EP1991248B1 (de) | 2012-04-11 |
| EP1991248A4 (de) | 2009-08-05 |
| CA2643892A1 (en) | 2007-09-07 |
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