CR10419A - Derivados de Pirazolo [3,4-D]-Pirimidina útiles para tratar trastornos respiratorios - Google Patents

Derivados de Pirazolo [3,4-D]-Pirimidina útiles para tratar trastornos respiratorios

Info

Publication number
CR10419A
CR10419A CR10419A CR10419A CR10419A CR 10419 A CR10419 A CR 10419A CR 10419 A CR10419 A CR 10419A CR 10419 A CR10419 A CR 10419A CR 10419 A CR10419 A CR 10419A
Authority
CR
Costa Rica
Prior art keywords
pyrazolo
pyrimidine derivatives
respiratory disorders
derivatives useful
treating respiratory
Prior art date
Application number
CR10419A
Other languages
English (en)
Inventor
Bruce Ian
Fox Hayler Judy
Charles Bloomfield Graham
Edwards Lee
Cox Brian
Howsham Catherine
Original Assignee
Novartis Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=36687588&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=CR10419(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Novartis Ag filed Critical Novartis Ag
Publication of CR10419A publication Critical patent/CR10419A/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
    • A61K31/5375—1,4-Oxazines, e.g. morpholine
    • A61K31/5377—1,4-Oxazines, e.g. morpholine not condensed and containing further heterocyclic rings, e.g. timolol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/06—Antiasthmatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/08—Bronchodilators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pulmonology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)

Abstract

La presente invención se refiere a un compuesto de la Fórmula (I): o una sal farmacúeticamente aceptable o un solvato del mismo, en donde R1-R3 e Y se definen en la descripción, y a su uso en el tratamiento de trastornos en donde esté implicada la cinasa pi3.
CR10419A 2006-05-23 2008-10-30 Derivados de Pirazolo [3,4-D]-Pirimidina útiles para tratar trastornos respiratorios CR10419A (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GBGB0610242.0A GB0610242D0 (en) 2006-05-23 2006-05-23 Organic compounds

Publications (1)

Publication Number Publication Date
CR10419A true CR10419A (es) 2011-07-19

Family

ID=36687588

Family Applications (1)

Application Number Title Priority Date Filing Date
CR10419A CR10419A (es) 2006-05-23 2008-10-30 Derivados de Pirazolo [3,4-D]-Pirimidina útiles para tratar trastornos respiratorios

Country Status (24)

Country Link
US (5) US20090131457A1 (es)
EP (1) EP2026811A1 (es)
JP (1) JP2009537580A (es)
KR (1) KR101106853B1 (es)
CN (1) CN101443013A (es)
AR (2) AR061057A1 (es)
AU (1) AU2007253615B2 (es)
BR (1) BRPI0712022A2 (es)
CA (1) CA2650661A1 (es)
CL (1) CL2007001455A1 (es)
CR (1) CR10419A (es)
EC (1) ECSP088902A (es)
GB (1) GB0610242D0 (es)
GT (1) GT200800256A (es)
IL (1) IL195017A0 (es)
MA (1) MA30433B1 (es)
MX (1) MX2008014835A (es)
NO (1) NO20084997L (es)
PE (1) PE20080315A1 (es)
RU (1) RU2008150619A (es)
TN (1) TNSN08478A1 (es)
TW (1) TW200806665A (es)
WO (1) WO2007134828A1 (es)
ZA (1) ZA200809097B (es)

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Also Published As

Publication number Publication date
CN101443013A (zh) 2009-05-27
US20140235632A1 (en) 2014-08-21
TW200806665A (en) 2008-02-01
EP2026811A1 (en) 2009-02-25
WO2007134828A1 (en) 2007-11-29
GT200800256A (es) 2009-05-28
US20160303132A1 (en) 2016-10-20
BRPI0712022A2 (pt) 2011-12-27
AR061057A1 (es) 2008-07-30
JP2009537580A (ja) 2009-10-29
GB0610242D0 (en) 2006-07-05
NO20084997L (no) 2008-12-22
CL2007001455A1 (es) 2008-05-16
TNSN08478A1 (en) 2010-04-14
RU2008150619A (ru) 2010-06-27
MX2008014835A (es) 2008-12-01
US20140051698A1 (en) 2014-02-20
US20090131457A1 (en) 2009-05-21
ZA200809097B (en) 2009-11-25
ECSP088902A (es) 2008-12-30
MA30433B1 (fr) 2009-05-04
CA2650661A1 (en) 2007-11-29
US20180125849A1 (en) 2018-05-10
AR110051A2 (es) 2019-02-20
KR20090008392A (ko) 2009-01-21
AU2007253615B2 (en) 2011-06-23
PE20080315A1 (es) 2008-06-11
KR101106853B1 (ko) 2012-01-19
AU2007253615A1 (en) 2007-11-29
US8901134B2 (en) 2014-12-02
IL195017A0 (en) 2009-08-03

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