CR10469A - Moleculas duales que contienen un derivado peroxidico, su sintesis y sus aplicaciones terapeuticas - Google Patents

Moleculas duales que contienen un derivado peroxidico, su sintesis y sus aplicaciones terapeuticas

Info

Publication number
CR10469A
CR10469A CR10469A CR10469A CR10469A CR 10469 A CR10469 A CR 10469A CR 10469 A CR10469 A CR 10469A CR 10469 A CR10469 A CR 10469A CR 10469 A CR10469 A CR 10469A
Authority
CR
Costa Rica
Prior art keywords
synthesis
therapeutic applications
molecules containing
dual molecules
optionally substituted
Prior art date
Application number
CR10469A
Other languages
English (en)
Inventor
Bernard Meunier
Frederic Cosledan
Alain Pellet
Original Assignee
Sanofi Aventis
Centre Nat Rech Scient
Palumed Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=37719816&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=CR10469(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Sanofi Aventis, Centre Nat Rech Scient, Palumed Sa filed Critical Sanofi Aventis
Publication of CR10469A publication Critical patent/CR10469A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A61K31/4709—Non-condensed quinolines and containing further heterocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
    • A61P33/06—Antimalarials
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)

Abstract

La invencion se refiere a las moleculas duales que responden a la formula (I): en la que:-A representa un resto de molecula con actividad antipaludica de formulas (IIa) o (IIIa) o un resto que facilita la biodisponibilidad;-B representa un grupo cicloalquilo sustituido opcionalmente, o bien B representa un grupo bi o triciclico que puede estar sustituido opcionalmente, o bien B representa 2 grupos cicloalquilo unidos entre si por un enlace sencillo o una cadena alquileno;-m y n representan independientemente el uno del otro 0, 1 o 2.
CR10469A 2006-06-13 2008-11-27 Moleculas duales que contienen un derivado peroxidico, su sintesis y sus aplicaciones terapeuticas CR10469A (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR0605235A FR2902100A1 (fr) 2006-06-13 2006-06-13 Molecules duales contenant un derive peroxydique, leur synthese et leurs applications en therapeutique

Publications (1)

Publication Number Publication Date
CR10469A true CR10469A (es) 2009-02-26

Family

ID=37719816

Family Applications (1)

Application Number Title Priority Date Filing Date
CR10469A CR10469A (es) 2006-06-13 2008-11-27 Moleculas duales que contienen un derivado peroxidico, su sintesis y sus aplicaciones terapeuticas

Country Status (24)

Country Link
US (1) US20120122923A1 (es)
EP (1) EP2032561A2 (es)
JP (1) JP2009539946A (es)
KR (1) KR20090029208A (es)
CN (1) CN101466706A (es)
AP (1) AP2008004711A0 (es)
AR (1) AR061347A1 (es)
AU (1) AU2007259116A1 (es)
BR (1) BRPI0713739A2 (es)
CA (1) CA2665940A1 (es)
CR (1) CR10469A (es)
EA (1) EA200970002A1 (es)
EC (1) ECSP088958A (es)
FR (1) FR2902100A1 (es)
IL (1) IL195394A0 (es)
MA (1) MA30577B1 (es)
MX (1) MX2008015980A (es)
NO (1) NO20085308L (es)
PE (1) PE20080335A1 (es)
TN (1) TNSN08462A1 (es)
TW (1) TW200817376A (es)
UY (1) UY30413A1 (es)
WO (1) WO2007144487A2 (es)
ZA (1) ZA200810012B (es)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2924343A1 (fr) * 2007-12-04 2009-06-05 Palumed Sa Nouvelles utilisations therapeutiques de molecules duales contenant un derive peroxydique.
WO2012122011A2 (en) 2011-03-04 2012-09-13 Glaxosmithkline Llc Amino-quinolines as kinase inhibitors
TWI547494B (zh) 2011-08-18 2016-09-01 葛蘭素史克智慧財產發展有限公司 作為激酶抑制劑之胺基喹唑啉類
TW201425307A (zh) 2012-09-13 2014-07-01 Glaxosmithkline Llc 作為激酶抑制劑之胺基－喹啉類
TWI592417B (zh) 2012-09-13 2017-07-21 葛蘭素史克智慧財產發展有限公司 胺基喹唑啉激酶抑制劑之前藥
TWI630203B (zh) 2013-02-21 2018-07-21 葛蘭素史克智慧財產發展有限公司 做為激酶抑制劑的喹唑啉類
CN119822967B (zh) * 2024-12-24 2025-12-30 万华化学集团股份有限公司 一种hmda的生产方法

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2133620A1 (en) * 1993-10-28 1995-04-29 Werner Hofheinz Aminoquinoline derivatives
ATE203519T1 (de) * 1995-11-16 2001-08-15 Hoffmann La Roche Chinolinderivate als antimalariamittel
CA2330564A1 (en) * 1998-04-29 1999-11-04 John Stephen Elder Quinolones used as mrs inhibitors and bactericides
FR2807433B1 (fr) * 2000-04-06 2002-09-20 Centre Nat Rech Scient Molecules duales contenant un derives peroxydique, leur synthese et leurs applications therapeutiques
US6486199B1 (en) * 2001-06-21 2002-11-26 Medicines For Malaria Venture Mmv International Centre Cointrin Spiro and dispiro 1,2,4-trioxolane antimalarials
WO2003070244A1 (en) * 2002-02-22 2003-08-28 Abbott Laboratories Antagonist of melanin concentrating hormone and their uses
SE0202134D0 (sv) * 2002-07-08 2002-07-08 Astrazeneca Ab Therapeutic agents
US20050256157A1 (en) * 2002-08-23 2005-11-17 Chiron Corporation Combination therapy with CHK1 inhibitors
CA2496164C (en) * 2002-08-23 2010-11-09 Chiron Corporation Benzimidazole quinolinones and uses thereof
US20050197350A1 (en) * 2003-03-31 2005-09-08 Taisho Pharmaceutical Co., Ltd. Novel quinoline, tetrahydroquinazoline, and pyrimidine derivatives and methods of treatment related to the use thereof
HU227684B1 (en) * 2003-08-29 2011-11-28 Sanofi Aventis Adamantane and azabicyclo-octane and nonane derivatives and their use as dpp-iv inhibitors
FR2862304A1 (fr) * 2003-11-14 2005-05-20 Centre Nat Rech Scient Molecules duales racemiques ou achirales contenant un derive peroxydique, leur synthese et leurs applications therapeutiques
EP1706384A1 (en) * 2004-01-07 2006-10-04 AstraZeneca AB Therapeutic agents i
AU2005283085B2 (en) * 2004-06-18 2012-06-21 3M Innovative Properties Company Substituted imidazoquinolines, imidazopyridines, and imidazonaphthyridines
FR2889525A1 (fr) * 2005-08-04 2007-02-09 Palumed Sa Nouveaux derives de polyquinoleines et leur utilisation therapeutique.

Also Published As

Publication number Publication date
TNSN08462A1 (en) 2010-04-14
WO2007144487A2 (fr) 2007-12-21
AR061347A1 (es) 2008-08-20
CA2665940A1 (fr) 2007-12-21
CN101466706A (zh) 2009-06-24
ECSP088958A (es) 2009-01-30
BRPI0713739A2 (pt) 2013-06-18
FR2902100A1 (fr) 2007-12-14
AU2007259116A8 (en) 2009-04-30
MX2008015980A (es) 2009-03-26
PE20080335A1 (es) 2008-05-22
WO2007144487A3 (fr) 2008-02-07
JP2009539946A (ja) 2009-11-19
UY30413A1 (es) 2008-01-31
AP2008004711A0 (en) 2008-12-31
IL195394A0 (en) 2009-08-03
MA30577B1 (fr) 2009-07-01
AU2007259116A1 (en) 2007-12-21
TW200817376A (en) 2008-04-16
NO20085308L (no) 2009-03-12
US20120122923A1 (en) 2012-05-17
EP2032561A2 (fr) 2009-03-11
KR20090029208A (ko) 2009-03-20
ZA200810012B (en) 2010-05-26
EA200970002A1 (ru) 2009-06-30

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Legal Events

Date Code Title Description
FA Abandonment or withdrawal (granting procedure)