CR10728A - Formas de dosificacion del clorhidrato de palonosetron que tienen estabilidad y biodisponibilidad mejorada - Google Patents

Formas de dosificacion del clorhidrato de palonosetron que tienen estabilidad y biodisponibilidad mejorada

Info

Publication number
CR10728A
CR10728A CR10728A CR10728A CR10728A CR 10728 A CR10728 A CR 10728A CR 10728 A CR10728 A CR 10728A CR 10728 A CR10728 A CR 10728A CR 10728 A CR10728 A CR 10728A
Authority
CR
Costa Rica
Prior art keywords
dosage forms
improved stability
palonosetron
biodisponibility
chlorhydrate
Prior art date
Application number
CR10728A
Other languages
English (en)
Inventor
Daniele Bonadeo
Giorgio Calderari
Riccardo Braglia
Enrico Braglia
Original Assignee
Helsinn Healthcare Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=38921772&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=CR10728(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Helsinn Healthcare Sa filed Critical Helsinn Healthcare Sa
Publication of CR10728A publication Critical patent/CR10728A/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A61K31/473—Quinolines; Isoquinolines ortho- or peri-condensed with carbocyclic ring systems, e.g. acridines, phenanthridines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4816—Wall or shell material
    • A61K9/4825—Proteins, e.g. gelatin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4841—Filling excipients; Inactive ingredients
    • A61K9/4858—Organic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5005—Wall or coating material
    • A61K9/5021—Organic macromolecular compounds
    • A61K9/5052—Proteins, e.g. albumin
    • A61K9/5057—Gelatin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/08—Drugs for disorders of the alimentary tract or the digestive system for nausea, cinetosis or vertigo; Antiemetics

Landscapes

  • Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Nutrition Science (AREA)
  • Physiology (AREA)
  • Organic Chemistry (AREA)
  • Otolaryngology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Hospice & Palliative Care (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

Siempre que sean forma de dosificacion orales solidas del clorhidrato de palonosetron, los metodos para usar las formas de dosificacion para tratar el vomito, y los metodos para hacer las formas de dosificacion. Las formas de dosificacion han mejorado la estabilidad y biodisponibilidad, y estan preferiblemente bajo la forma de capsulas rellenas de liquido.
CR10728A 2006-10-24 2009-04-17 Formas de dosificacion del clorhidrato de palonosetron que tienen estabilidad y biodisponibilidad mejorada CR10728A (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US85434206P 2006-10-24 2006-10-24

Publications (1)

Publication Number Publication Date
CR10728A true CR10728A (es) 2009-07-23

Family

ID=38921772

Family Applications (1)

Application Number Title Priority Date Filing Date
CR10728A CR10728A (es) 2006-10-24 2009-04-17 Formas de dosificacion del clorhidrato de palonosetron que tienen estabilidad y biodisponibilidad mejorada

Country Status (35)

Country Link
US (2) US20080152704A1 (es)
EP (1) EP1940366B9 (es)
JP (1) JP5144527B2 (es)
KR (1) KR101441459B1 (es)
CN (1) CN101573106B (es)
AR (1) AR063362A1 (es)
AT (1) ATE427742T1 (es)
AU (1) AU2007308378B2 (es)
BR (1) BRPI0718497B1 (es)
CA (1) CA2666512C (es)
CL (1) CL2007003055A1 (es)
CO (1) CO6160289A2 (es)
CR (1) CR10728A (es)
CY (1) CY1109914T1 (es)
DE (1) DE602007000856D1 (es)
DK (1) DK1940366T3 (es)
EA (1) EA016455B1 (es)
ES (1) ES2325339T3 (es)
GT (1) GT200900096A (es)
HN (1) HN2009000785A (es)
HR (1) HRP20090341T1 (es)
IL (1) IL198225A (es)
ME (1) ME01949B (es)
MX (1) MX2009004461A (es)
NO (1) NO342353B1 (es)
NZ (1) NZ576237A (es)
PL (1) PL1940366T3 (es)
PT (1) PT1940366E (es)
RS (1) RS50842B (es)
SI (1) SI1940366T1 (es)
SV (1) SV2009003238A (es)
TW (1) TWI367212B (es)
UA (1) UA97653C2 (es)
WO (1) WO2008049552A1 (es)
ZA (1) ZA200902773B (es)

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US20070196491A1 (en) * 2006-01-27 2007-08-23 Eurand, Inc. Drug delivery systems comprising weakly basic drugs and organic acids
JP5433236B2 (ja) * 2006-01-27 2014-03-05 アプタリス ファーマテック，インコーポレイテッド 弱塩基性選択性セロトニン５−ｈｔ３遮断剤および有機酸を含む薬物送達系
EP2364138A2 (en) * 2008-12-08 2011-09-14 Teva Pharmaceutical Industries Ltd. Palonosetron formulation
US20110003005A1 (en) * 2009-07-06 2011-01-06 Gopi Venkatesh Methods of Treating PDNV and PONV with Extended Release Ondansetron Compositions
CN102048705B (zh) * 2009-11-10 2012-07-18 齐鲁制药有限公司 盐酸帕洛诺司琼口腔崩解片制剂及其制备方法
EP2499137A1 (en) * 2009-11-13 2012-09-19 Helsinn Healthcare S.A. Palonosetron metabolites
EP2722045B1 (en) 2009-11-18 2016-07-06 Helsinn Healthcare SA Compositions for treating centrally mediated nausea and vomiting
PE20121483A1 (es) 2009-11-18 2012-12-02 Helsinn Healthcare Sa Composiciones para tratar nausea y vomito centralmente mediados
WO2013057554A2 (en) 2011-10-18 2013-04-25 Helsinn Healthcare Sa Therapeutic combinations of netupitant and palonosetron
CN107137374B (zh) * 2012-06-02 2020-04-07 正大天晴药业集团股份有限公司 帕洛诺司琼的固体药物组合物
ES2692881T3 (es) * 2013-03-19 2018-12-05 Galenicum Health S.L. Composiciones farmacéuticas que comprenden un agente activo
CA3042642A1 (en) 2013-08-12 2015-02-19 Pharmaceutical Manufacturing Research Services, Inc. Extruded immediate release abuse deterrent pill
US9492444B2 (en) 2013-12-17 2016-11-15 Pharmaceutical Manufacturing Research Services, Inc. Extruded extended release abuse deterrent pill
WO2015095391A1 (en) 2013-12-17 2015-06-25 Pharmaceutical Manufacturing Research Services, Inc. Extruded extended release abuse deterrent pill
EP3087987A4 (en) 2013-12-23 2017-08-02 Samyang Biopharmaceuticals Corporation Pharmaceutical composition containing palonosetron
DK3169315T3 (da) 2014-07-17 2020-08-10 Pharmaceutical Manufacturing Res Services In Væskefyldt doseringsform til forhindring af misbrug med øjeblikkelig frigivelse
AU2015336065A1 (en) * 2014-10-20 2017-05-04 Pharmaceutical Manufacturing Research Services, Inc. Extended release abuse deterrent liquid fill dosage form
KR20160128573A (ko) * 2015-04-29 2016-11-08 주식회사 삼양바이오팜 약제학적 패키지
JP2019019067A (ja) * 2017-07-13 2019-02-07 ニプロ株式会社 液体製剤
CN111205283A (zh) * 2020-01-20 2020-05-29 广州九植医药科技有限公司 一种盐酸帕洛诺司琼有关物质b的合成方法
AU2023393578A1 (en) 2022-12-12 2025-07-03 Alfred E. Tiefenbacher (Gmbh & Co. Kg) Fixed dose combination comprising netupitant and palonosetron
EP4385500B1 (en) 2022-12-12 2026-07-01 Alfred E. Tiefenbacher (GmbH & Co. KG) FIXED-DOSE COMBINATION INCLUDING NETUPITANT AND PALONOSETRON
EP4385497A1 (en) 2022-12-12 2024-06-19 Alfred E. Tiefenbacher (GmbH & Co. KG) Antioxidant-free fixed dose combination of netupitant and palonosetron
EP4633608A1 (en) 2022-12-12 2025-10-22 Alfred E. Tiefenbacher (GmbH & Co. KG) Antioxidant-free fixed dose combination of netupitant and palonosetron

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Also Published As

Publication number Publication date
CA2666512C (en) 2014-05-27
KR101441459B1 (ko) 2014-09-18
PT1940366E (pt) 2009-06-17
IL198225A0 (en) 2009-12-24
ZA200902773B (en) 2010-03-31
TW200827355A (en) 2008-07-01
US20170035748A1 (en) 2017-02-09
ME01949B (me) 2010-08-31
CA2666512A1 (en) 2008-05-02
AU2007308378B2 (en) 2013-02-21
EP1940366B1 (en) 2009-04-08
AU2007308378A1 (en) 2008-05-02
IL198225A (en) 2013-03-24
BRPI0718497B1 (pt) 2024-02-06
RS50842B (sr) 2010-08-31
CY1109914T1 (el) 2014-09-10
KR20090073234A (ko) 2009-07-02
WO2008049552A1 (en) 2008-05-02
NO342353B1 (no) 2018-05-07
EA200970396A1 (ru) 2009-10-30
CO6160289A2 (es) 2010-05-20
EP1940366B9 (en) 2009-12-02
DK1940366T3 (da) 2009-06-29
MX2009004461A (es) 2009-09-16
GT200900096A (es) 2011-08-29
CN101573106A (zh) 2009-11-04
CN101573106B (zh) 2013-07-24
HRP20090341T1 (hr) 2009-07-31
NO20091945L (no) 2009-05-25
US20080152704A1 (en) 2008-06-26
TWI367212B (en) 2012-07-01
PL1940366T3 (pl) 2009-09-30
CL2007003055A1 (es) 2008-03-24
ATE427742T1 (de) 2009-04-15
NZ576237A (en) 2011-12-22
ES2325339T3 (es) 2009-09-01
JP2009507933A (ja) 2009-02-26
HN2009000785A (es) 2011-10-14
EA016455B1 (ru) 2012-05-30
HK1117769A1 (en) 2009-01-23
JP5144527B2 (ja) 2013-02-13
BRPI0718497A2 (pt) 2014-07-08
DE602007000856D1 (de) 2009-05-20
SV2009003238A (es) 2009-11-09
SI1940366T1 (sl) 2009-08-31
UA97653C2 (ru) 2012-03-12
AR063362A1 (es) 2009-01-21
EP1940366A1 (en) 2008-07-09

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