CR10772A - Derivados de pirrol, su preparacion y su utilizacion en terapeutica - Google Patents

Derivados de pirrol, su preparacion y su utilizacion en terapeutica

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Publication number
CR10772A
CR10772A CR10772A CR10772A CR10772A CR 10772 A CR10772 A CR 10772A CR 10772 A CR10772 A CR 10772A CR 10772 A CR10772 A CR 10772A CR 10772 A CR10772 A CR 10772A
Authority
CR
Costa Rica
Prior art keywords
substituted
pirrol
therapeutics
derivatives
preparation
Prior art date
Application number
CR10772A
Other languages
English (en)
Inventor
Francis Barth
Christian Congy
Laurent Hortala
Murielle Rinaldi-Carmona
Original Assignee
Sanofi Aventis
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=38521242&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=CR10772(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Sanofi Aventis filed Critical Sanofi Aventis
Publication of CR10772A publication Critical patent/CR10772A/es

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    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
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    • C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/04—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D207/10—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D207/16—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
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    • C07D207/30—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
    • C07D207/34—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
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    • C07D317/44—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D317/46—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 ortho- or peri-condensed with carbocyclic rings or ring systems condensed with one six-membered ring
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Abstract

La invencion tiene por objeto compuestos que responden a la formula (I) en la que A representa: un grupo alquileno (C1-C6) no sustituido o sustituido; un grupo Formula (II) con m = 0, 1, o 2 y p = 0 o 1; R1 representa hidrogeno o un alquilo (C1-C4); R2 representa: un grupo alquilo (C3-C10) no sustituido o sustituido; un radical carbociclico no aromatico de C3-C12, no sustituido o sustituido.
CR10772A 2006-11-20 2009-05-06 Derivados de pirrol, su preparacion y su utilizacion en terapeutica CR10772A (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR0610202A FR2908766B1 (fr) 2006-11-20 2006-11-20 Derives de pyrrole,leur preparation et leur utilisation en therapeutique.

Publications (1)

Publication Number Publication Date
CR10772A true CR10772A (es) 2009-07-23

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Application Number Title Priority Date Filing Date
CR10772A CR10772A (es) 2006-11-20 2009-05-06 Derivados de pirrol, su preparacion y su utilizacion en terapeutica

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US (1) US8044072B2 (es)
EP (1) EP2094656B1 (es)
JP (1) JP5210320B2 (es)
KR (1) KR20090080992A (es)
CN (1) CN101535250A (es)
AR (1) AR064596A1 (es)
AT (1) ATE520654T1 (es)
AU (1) AU2007330651A1 (es)
BR (1) BRPI0718962A2 (es)
CA (1) CA2669996A1 (es)
CL (1) CL2007003318A1 (es)
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FR2930939B1 (fr) * 2008-05-09 2010-07-30 Sanofi Aventis Derives de pyrrole, leur preparation et leur application en therapeutique
FR2930940B1 (fr) * 2008-05-09 2011-02-11 Sanofi Aventis Derives de pyrrole, leur preparation et leur application en therapeutique
CN102964304B (zh) * 2012-09-28 2015-06-17 苏州大学 含吡唑烷酮结构的手性氨基氰化物的制备方法
CN109563032B (zh) 2016-07-12 2022-05-20 广东众生睿创生物科技有限公司 作为ppar激动剂的吡咯烷衍生物
AU2018391211B2 (en) * 2017-12-21 2020-12-17 Guangdong Raynovent Biotech Co., Ltd. Amorphous pyrrolidine derivative as PPAR agonist and preparation method thereof
AU2019387370A1 (en) 2018-11-30 2021-06-10 Nuvation Bio Inc. Pyrrole and pyrazole compounds and methods of use thereof
CN116903511A (zh) * 2023-06-25 2023-10-20 南方海洋科学与工程广东省实验室(湛江) 一种吡咯类生物碱衍生物及其在制备具有抗炎作用的药物中的应用

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US8044072B2 (en) 2011-10-25
EP2094656A2 (fr) 2009-09-02
ATE520654T1 (de) 2011-09-15
AU2007330651A1 (en) 2008-06-12
SV2009003265A (es) 2010-02-05
ZA200903865B (en) 2010-08-25
MX2009005366A (es) 2009-06-08
US20090281116A1 (en) 2009-11-12
FR2908766A1 (fr) 2008-05-23
IL198481A0 (en) 2010-02-17
EA200970497A1 (ru) 2009-10-30
TW200829565A (en) 2008-07-16
FR2908766B1 (fr) 2009-01-09
WO2008068423A2 (fr) 2008-06-12
WO2008068423A3 (fr) 2008-07-31
UY30729A1 (es) 2008-07-03
NO20092066L (no) 2009-08-11
CA2669996A1 (fr) 2008-06-12
KR20090080992A (ko) 2009-07-27
BRPI0718962A2 (pt) 2013-12-17
JP2010510198A (ja) 2010-04-02
EP2094656B1 (fr) 2011-08-17
TN2009000166A1 (fr) 2010-10-18
PE20081495A1 (es) 2008-12-31
ECSP099339A (es) 2009-06-30
DOP2009000105A (es) 2009-05-31
AR064596A1 (es) 2009-04-15
MA30996B1 (fr) 2009-12-01
CL2007003318A1 (es) 2008-07-04
CN101535250A (zh) 2009-09-16

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