CR20110577A - Proteínas de unión a il-1 - Google Patents

Proteínas de unión a il-1

Info

Publication number
CR20110577A
CR20110577A CR20110577A CR20110577A CR20110577A CR 20110577 A CR20110577 A CR 20110577A CR 20110577 A CR20110577 A CR 20110577A CR 20110577 A CR20110577 A CR 20110577A CR 20110577 A CR20110577 A CR 20110577A
Authority
CR
Costa Rica
Prior art keywords
antibodies
proteins
union
union proteins
antibody
Prior art date
Application number
CR20110577A
Other languages
English (en)
Inventor
Chung-Ming Hsieh
Chengbin Wu
Original Assignee
Abbott Lab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Abbott Lab filed Critical Abbott Lab
Publication of CR20110577A publication Critical patent/CR20110577A/es

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    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A61K39/39533—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
    • A61K39/3955—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against proteinaceous materials, e.g. enzymes, hormones, lymphokines
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/24—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
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    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
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    • A61K47/68—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an antibody, an immunoglobulin or a fragment thereof, e.g. an Fc-fragment
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Abstract

Proteínas que se unen a la IL-1 . Anticuerpos que son anticuerpos quiméricos, anticuerpos que tienen CDR injertadas o anticuerpos humanizados. Los anticuerpos de la invención presentan una afinidad elevada por la IL-1 y neutralizan la actividad de la IL-1 . Un anticuerpo de la invención puede ser un anticuerpo completo o una porción de unión al antígeno de éste.
CR20110577A 2009-01-29 2011-11-07 Proteínas de unión a il-1 CR20110577A (es)

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TW201031421A (en) 2010-09-01
BRPI1007371A2 (pt) 2018-03-27
WO2010087972A3 (en) 2010-09-16
CL2011001834A1 (es) 2012-03-09
EP2391652A4 (en) 2013-01-02
CO6400231A2 (es) 2012-03-15
UA102722C2 (en) 2013-08-12
WO2010087972A2 (en) 2010-08-05
US8383778B2 (en) 2013-02-26
ZA201105177B (en) 2012-03-28
KR20110110349A (ko) 2011-10-06
MX2011007987A (es) 2011-08-17
JP2012516153A (ja) 2012-07-19
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AU2010208637A1 (en) 2011-08-04
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ECSP11011239A (es) 2011-08-31
SG172855A1 (en) 2011-08-29
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CA2749966A1 (en) 2010-08-05
RU2011135768A (ru) 2013-03-10

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