CR20110586A - Combinación antitumoral que comprende cabazitaxel y capecitabina - Google Patents
Combinación antitumoral que comprende cabazitaxel y capecitabinaInfo
- Publication number
- CR20110586A CR20110586A CR20110586A CR20110586A CR20110586A CR 20110586 A CR20110586 A CR 20110586A CR 20110586 A CR20110586 A CR 20110586A CR 20110586 A CR20110586 A CR 20110586A CR 20110586 A CR20110586 A CR 20110586A
- Authority
- CR
- Costa Rica
- Prior art keywords
- capecitabina
- combination including
- cabazitaxel
- antitumoral combination
- antitumoral
- Prior art date
Links
- GAGWJHPBXLXJQN-UORFTKCHSA-N Capecitabine Chemical compound C1=C(F)C(NC(=O)OCCCCC)=NC(=O)N1[C@H]1[C@H](O)[C@H](O)[C@@H](C)O1 GAGWJHPBXLXJQN-UORFTKCHSA-N 0.000 title abstract 2
- 230000000259 anti-tumor effect Effects 0.000 title abstract 2
- BMQGVNUXMIRLCK-OAGWZNDDSA-N cabazitaxel Chemical compound O([C@H]1[C@@H]2[C@]3(OC(C)=O)CO[C@@H]3C[C@@H]([C@]2(C(=O)[C@H](OC)C2=C(C)[C@@H](OC(=O)[C@H](O)[C@@H](NC(=O)OC(C)(C)C)C=3C=CC=CC=3)C[C@]1(O)C2(C)C)C)OC)C(=O)C1=CC=CC=C1 BMQGVNUXMIRLCK-OAGWZNDDSA-N 0.000 title abstract 2
- 229960001573 cabazitaxel Drugs 0.000 title abstract 2
- 206010055113 Breast cancer metastatic Diseases 0.000 abstract 1
- GAGWJHPBXLXJQN-UHFFFAOYSA-N Capecitabine Natural products C1=C(F)C(NC(=O)OCCCCC)=NC(=O)N1C1C(O)C(O)C(C)O1 GAGWJHPBXLXJQN-UHFFFAOYSA-N 0.000 abstract 1
- 229940123237 Taxane Drugs 0.000 abstract 1
- 239000002253 acid Substances 0.000 abstract 1
- 229940045799 anthracyclines and related substance Drugs 0.000 abstract 1
- 239000002246 antineoplastic agent Substances 0.000 abstract 1
- 229960004117 capecitabine Drugs 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 239000012453 solvate Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/337—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having four-membered rings, e.g. taxol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
- A61K31/7052—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides
- A61K31/706—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom
- A61K31/7064—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines
- A61K31/7068—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines having oxo groups directly attached to the pyrimidine ring, e.g. cytidine, cytidylic acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/04—Antineoplastic agents specific for metastasis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Molecular Biology (AREA)
- Engineering & Computer Science (AREA)
- Oncology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
La invención se refiere a una combinación farmacéutica antitumoral que comprende cabazitaxel y capecitabina, pudiendo estar estos dos agentes antitumorales en forma de base, en forma de una sal de un ácido farmacéuticamente aceptable o en forma de un hidrato o de un solvato, destinada a tratar el cáncer de mama metastásico en los pacientes que progresan después de un tratamiento anterior con antraciclinas y taxanos.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR0902189A FR2945211A1 (fr) | 2009-05-06 | 2009-05-06 | Combinaison antitumorale comprenant la cabazitaxel et la capecitabine |
| FR0902264A FR2945212B1 (fr) | 2009-05-06 | 2009-05-11 | Combinaison antitumorale comprenant le cabazitaxel et la capecitabine |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CR20110586A true CR20110586A (es) | 2011-12-13 |
Family
ID=41168737
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CR20110586A CR20110586A (es) | 2009-05-06 | 2011-11-08 | Combinación antitumoral que comprende cabazitaxel y capecitabina |
Country Status (25)
| Country | Link |
|---|---|
| US (1) | US20120115806A1 (es) |
| EP (1) | EP2427187A1 (es) |
| JP (1) | JP2012526089A (es) |
| KR (1) | KR20120008069A (es) |
| CN (1) | CN102458392A (es) |
| AU (1) | AU2010244253A1 (es) |
| BR (1) | BRPI1011827A2 (es) |
| CA (1) | CA2761079A1 (es) |
| CL (1) | CL2011002774A1 (es) |
| CO (1) | CO6390103A2 (es) |
| CR (1) | CR20110586A (es) |
| DO (1) | DOP2011000336A (es) |
| EA (1) | EA201171360A1 (es) |
| EC (1) | ECSP11011435A (es) |
| FR (2) | FR2945211A1 (es) |
| IL (1) | IL216063A0 (es) |
| MA (1) | MA33343B1 (es) |
| MX (1) | MX2011011765A (es) |
| NI (1) | NI201100192A (es) |
| NZ (1) | NZ596226A (es) |
| PE (1) | PE20120348A1 (es) |
| SG (1) | SG175894A1 (es) |
| TN (1) | TN2011000542A1 (es) |
| WO (1) | WO2010128258A1 (es) |
| ZA (1) | ZA201108109B (es) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102770131A (zh) | 2009-10-29 | 2012-11-07 | 安万特医药股份有限公司 | 卡巴他赛的新颖抗肿瘤用途 |
| CN102068407B (zh) * | 2010-12-27 | 2011-11-23 | 江苏奥赛康药业股份有限公司 | 一种cabazitaxel注射液及其制备方法 |
| HUE046232T2 (hu) * | 2011-02-25 | 2020-02-28 | Sanofi Mature Ip | Kabazitaxelt és ciszplatint tartalmazó tumorellenes kombináció |
| EP2491925A1 (en) | 2011-02-25 | 2012-08-29 | Aventis Pharma S.A. | Antitumoral combination comprising cabazitaxel and cisplatin |
| EP2620148A1 (en) | 2012-01-27 | 2013-07-31 | Aventis Pharma S.A. | Antitumoral combination comprising cabazitaxel and cisplatin |
| CA2953371C (en) * | 2014-06-30 | 2021-08-24 | Tarveda Therapeutics, Inc. | Targeted conjugates and particles and formulations thereof |
| JP7057278B2 (ja) | 2015-10-28 | 2022-04-19 | ターベダ セラピューティクス インコーポレイテッド | Ｓｓｔｒ標的化コンジュゲート及び粒子並びにその製剤 |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU671491B2 (en) | 1992-12-18 | 1996-08-29 | F. Hoffmann-La Roche Ag | N-oxycarbonyl substituted 5'-deoxy-5-fluorcytidines |
| MA23823A1 (fr) | 1995-03-27 | 1996-10-01 | Aventis Pharma Sa | Nouveaux taxoides, leur preparation et les compositions qui les contiennent |
| FR2859996B1 (fr) * | 2003-09-19 | 2006-02-03 | Aventis Pharma Sa | Solvat acetonique du dimethoxy docetaxel et son procede de preparation |
-
2009
- 2009-05-06 FR FR0902189A patent/FR2945211A1/fr active Pending
- 2009-05-11 FR FR0902264A patent/FR2945212B1/fr not_active Expired - Fee Related
-
2010
- 2010-05-06 CA CA2761079A patent/CA2761079A1/fr not_active Abandoned
- 2010-05-06 SG SG2011081353A patent/SG175894A1/en unknown
- 2010-05-06 CN CN2010800304295A patent/CN102458392A/zh active Pending
- 2010-05-06 KR KR1020117029019A patent/KR20120008069A/ko not_active Withdrawn
- 2010-05-06 EP EP10727466A patent/EP2427187A1/fr not_active Withdrawn
- 2010-05-06 PE PE2011001906A patent/PE20120348A1/es not_active Application Discontinuation
- 2010-05-06 NZ NZ596226A patent/NZ596226A/en not_active IP Right Cessation
- 2010-05-06 MX MX2011011765A patent/MX2011011765A/es not_active Application Discontinuation
- 2010-05-06 AU AU2010244253A patent/AU2010244253A1/en not_active Abandoned
- 2010-05-06 MA MA34423A patent/MA33343B1/fr unknown
- 2010-05-06 WO PCT/FR2010/050873 patent/WO2010128258A1/fr not_active Ceased
- 2010-05-06 JP JP2012509077A patent/JP2012526089A/ja not_active Withdrawn
- 2010-05-06 BR BRPI1011827A patent/BRPI1011827A2/pt not_active IP Right Cessation
- 2010-05-06 EA EA201171360A patent/EA201171360A1/ru unknown
-
2011
- 2011-10-24 TN TNP2011000542A patent/TN2011000542A1/fr unknown
- 2011-10-31 IL IL216063A patent/IL216063A0/en unknown
- 2011-11-01 EC EC2011011435A patent/ECSP11011435A/es unknown
- 2011-11-02 DO DO2011000336A patent/DOP2011000336A/es unknown
- 2011-11-04 CO CO11149811A patent/CO6390103A2/es not_active Application Discontinuation
- 2011-11-04 NI NI201100192A patent/NI201100192A/es unknown
- 2011-11-04 ZA ZA2011/08109A patent/ZA201108109B/en unknown
- 2011-11-04 CL CL2011002774A patent/CL2011002774A1/es unknown
- 2011-11-04 US US13/289,250 patent/US20120115806A1/en not_active Abandoned
- 2011-11-08 CR CR20110586A patent/CR20110586A/es not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| EP2427187A1 (fr) | 2012-03-14 |
| BRPI1011827A2 (pt) | 2016-03-22 |
| FR2945212A1 (fr) | 2010-11-12 |
| US20120115806A1 (en) | 2012-05-10 |
| MA33343B1 (fr) | 2012-06-01 |
| ECSP11011435A (es) | 2011-12-30 |
| SG175894A1 (en) | 2011-12-29 |
| EA201171360A1 (ru) | 2012-05-30 |
| MX2011011765A (es) | 2012-06-01 |
| CN102458392A (zh) | 2012-05-16 |
| WO2010128258A1 (fr) | 2010-11-11 |
| JP2012526089A (ja) | 2012-10-25 |
| DOP2011000336A (es) | 2011-12-15 |
| FR2945211A1 (fr) | 2010-11-12 |
| NI201100192A (es) | 2012-01-23 |
| CO6390103A2 (es) | 2012-02-29 |
| NZ596226A (en) | 2014-01-31 |
| KR20120008069A (ko) | 2012-01-25 |
| ZA201108109B (en) | 2013-01-30 |
| IL216063A0 (en) | 2012-01-31 |
| AU2010244253A1 (en) | 2011-11-24 |
| CL2011002774A1 (es) | 2012-04-20 |
| FR2945212B1 (fr) | 2011-07-01 |
| CA2761079A1 (fr) | 2010-11-11 |
| TN2011000542A1 (fr) | 2013-05-24 |
| PE20120348A1 (es) | 2012-04-24 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FA | Abandonment or withdrawal (granting procedure) |