CR20120413A - Derivados de fumarato de ácido graso y sus usos - Google Patents

Derivados de fumarato de ácido graso y sus usos

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Publication number
CR20120413A
CR20120413A CR20120413A CR20120413A CR20120413A CR 20120413 A CR20120413 A CR 20120413A CR 20120413 A CR20120413 A CR 20120413A CR 20120413 A CR20120413 A CR 20120413A CR 20120413 A CR20120413 A CR 20120413A
Authority
CR
Costa Rica
Prior art keywords
fatty acid
derivatives
fumarate
acid fumarate
compositions
Prior art date
Application number
CR20120413A
Other languages
English (en)
Inventor
Chi B Vu
Jean E Bemis
Michael R Jirousek
Jill C Milne
Jesse J Smith
Original Assignee
Catabasis Pharmaceuticals Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=44258993&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=CR20120413(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Catabasis Pharmaceuticals Inc filed Critical Catabasis Pharmaceuticals Inc
Publication of CR20120413A publication Critical patent/CR20120413A/es

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C235/00—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms
    • C07C235/70—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups and doubly-bound oxygen atoms bound to the same carbon skeleton
    • C07C235/72—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups and doubly-bound oxygen atoms bound to the same carbon skeleton with the carbon atoms of the carboxamide groups bound to acyclic carbon atoms
    • C07C235/76—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups and doubly-bound oxygen atoms bound to the same carbon skeleton with the carbon atoms of the carboxamide groups bound to acyclic carbon atoms of an unsaturated carbon skeleton
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    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/20—Carboxylic acids, e.g. valproic acid having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids
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    • A61K47/55—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic compound the modifying agent being also a pharmacologically or therapeutically active agent, i.e. the entire conjugate being a codrug
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    • C07C233/16—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by singly-bound oxygen atoms
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    • C07C233/20—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by singly-bound oxygen atoms with the substituted hydrocarbon radical bound to the nitrogen atom of the carboxamide group by an acyclic carbon atom having the carbon atom of the carboxamide group bound to a carbon atom of an acyclic unsaturated carbon skeleton
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    • C07C233/35—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by amino groups with the substituted hydrocarbon radical bound to the nitrogen atom of the carboxamide group by an acyclic carbon atom
    • C07C233/38—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by amino groups with the substituted hydrocarbon radical bound to the nitrogen atom of the carboxamide group by an acyclic carbon atom having the carbon atom of the carboxamide group bound to a carbon atom of an acyclic unsaturated carbon skeleton
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Abstract

La invención se refiere a derivados de fumarato de ácido graso, a composiciones que comprenden una cantidad efectiva de un derivado de fumarato de ácido graso y a métodos para tratar o prevenir cáncer, un trastorno metabólico o trastorno neurodegenerativo que comprende
CR20120413A 2010-01-08 2012-08-08 Derivados de fumarato de ácido graso y sus usos CR20120413A (es)

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AR080357A1 (es) 2012-04-04
IL244858A0 (en) 2016-05-31
EP2521447B1 (en) 2017-06-14
KR101828616B1 (ko) 2018-02-12
AU2011204277B2 (en) 2015-12-24
JP2013516486A (ja) 2013-05-13
RU2012134069A (ru) 2014-02-20
CL2012001911A1 (es) 2012-10-26
PH12012501390A1 (en) 2012-10-29
DK2521447T3 (en) 2017-09-18
AU2011204277A1 (en) 2012-08-30
MX337605B (es) 2016-03-10
CN102821602B (zh) 2016-04-20
US20130065909A1 (en) 2013-03-14
IL244858A (en) 2016-12-29
KR20120123407A (ko) 2012-11-08
CO6571913A2 (es) 2012-11-30
NZ601698A (en) 2015-04-24
US8969354B2 (en) 2015-03-03
CA2786605A1 (en) 2011-07-14
NI201200120A (es) 2013-06-12
JP5771627B2 (ja) 2015-09-02
EP2521447A4 (en) 2014-04-30
EP2521447A1 (en) 2012-11-14
US9289503B2 (en) 2016-03-22
US20150238618A1 (en) 2015-08-27
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US20110172240A1 (en) 2011-07-14
SG182414A1 (en) 2012-08-30
ECSP12012097A (es) 2012-09-28
US20160340294A1 (en) 2016-11-24
MX2012007981A (es) 2012-08-23
TWI508725B (zh) 2015-11-21
TW201141471A (en) 2011-12-01
BR112012016879A2 (pt) 2015-09-01
WO2011085211A1 (en) 2011-07-14
MY160249A (en) 2017-02-28

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