CR20170020A - Variantes de proteínas de unión al factor h y métodos de uso de estas - Google Patents
Variantes de proteínas de unión al factor h y métodos de uso de estasInfo
- Publication number
- CR20170020A CR20170020A CR20170020A CR20170020A CR20170020A CR 20170020 A CR20170020 A CR 20170020A CR 20170020 A CR20170020 A CR 20170020A CR 20170020 A CR20170020 A CR 20170020A CR 20170020 A CR20170020 A CR 20170020A
- Authority
- CR
- Costa Rica
- Prior art keywords
- methods
- factor
- unions
- variants
- protein
- Prior art date
Links
- 102000004169 proteins and genes Human genes 0.000 title abstract 3
- 108090000623 proteins and genes Proteins 0.000 title abstract 3
- 102100030386 Granzyme A Human genes 0.000 abstract 1
- 101001009599 Homo sapiens Granzyme A Proteins 0.000 abstract 1
- 241000588650 Neisseria meningitidis Species 0.000 abstract 1
- 230000000844 anti-bacterial effect Effects 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/02—Bacterial antigens
- A61K39/095—Neisseria
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/04—Immunostimulants
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
- C07K14/22—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Neisseriaceae (F)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
- A61K2039/55505—Inorganic adjuvants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/57—Medicinal preparations containing antigens or antibodies characterised by the type of response, e.g. Th1, Th2
- A61K2039/575—Medicinal preparations containing antigens or antibodies characterised by the type of response, e.g. Th1, Th2 humoral response
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Organic Chemistry (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Immunology (AREA)
- Epidemiology (AREA)
- Mycology (AREA)
- Microbiology (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Gastroenterology & Hepatology (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Peptides Or Proteins (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Abstract
Se brindan proteínas variantes de unión al factor H que pueden provocar anticuerpos bactericidas para al menos una cepa de Neisseria meningitidis, composiciones que comprenden dichas proteínas y métodos de uso de dichas proteínas.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201462028123P | 2014-07-23 | 2014-07-23 | |
| PCT/US2015/041616 WO2016014719A1 (en) | 2014-07-23 | 2015-07-22 | Factor h binding protein variants and methods of use thereof |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CR20170020A true CR20170020A (es) | 2017-08-10 |
Family
ID=55163727
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CR20170020A CR20170020A (es) | 2014-07-23 | 2015-07-22 | Variantes de proteínas de unión al factor h y métodos de uso de estas |
Country Status (15)
| Country | Link |
|---|---|
| US (10) | US10266572B2 (es) |
| EP (2) | EP3172224B1 (es) |
| JP (4) | JP6796057B2 (es) |
| KR (2) | KR102761870B1 (es) |
| CN (3) | CN119613509A (es) |
| AU (5) | AU2015292615B2 (es) |
| BR (1) | BR112017001417B1 (es) |
| CA (2) | CA2955802C (es) |
| CO (1) | CO2017000558A2 (es) |
| CR (1) | CR20170020A (es) |
| ES (1) | ES2922554T3 (es) |
| MX (3) | MX382409B (es) |
| NZ (2) | NZ766005A (es) |
| RU (1) | RU2714248C2 (es) |
| WO (1) | WO2016014719A1 (es) |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| BR122021020829B8 (pt) | 2010-03-30 | 2022-12-27 | Children´S Hospital & Res Center At Oakland | Proteína de ligação ao fator h de ocorrência não natural (fhbp), composição, e célula hospedeira de neisseria meningitidis geneticamente modificada |
| KR102761870B1 (ko) | 2014-07-23 | 2025-02-05 | 칠드런즈 하스피틀 앤드 리써치 센터 앳 오클랜드 | 인자 h 결합 단백질 변이체 및 이의 사용 방법 |
| GB201614687D0 (en) * | 2016-08-31 | 2016-10-12 | Univ Oxford Innovation Ltd | fHbp scaffold |
| KR101855133B1 (ko) | 2016-11-16 | 2018-05-08 | 주식회사 케이엠더블유 | 적층구조의 mimo 안테나 어셈블리 |
| WO2018093176A2 (ko) | 2016-11-16 | 2018-05-24 | 주식회사 케이엠더블유 | 적층구조의 mimo 안테나 어셈블리 |
| AU2018379236B2 (en) * | 2017-12-04 | 2025-02-27 | Intravacc B.V. | An improved process for producing outer membrane vesicles |
| EP3607967A1 (en) | 2018-08-09 | 2020-02-12 | GlaxoSmithKline Biologicals S.A. | Modified meningococcal fhbp polypeptides |
| GB202016604D0 (en) | 2020-10-20 | 2020-12-02 | Univ Of Oxford | Compositions and methods for inducing an immune response |
| CA3211240A1 (en) | 2021-02-19 | 2022-08-25 | Sanofi Pasteur Inc. | Meningococcal b recombinant vaccine |
| TW202423477A (zh) | 2022-08-03 | 2024-06-16 | 美商賽諾菲巴斯德公司 | 針對腦膜炎奈瑟氏菌b的含佐劑免疫原性組成物 |
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| BR112016002150A2 (pt) | 2013-08-02 | 2017-09-12 | Children´S Hospital & Res Center At Oakland | proteínas de ligação de fator h de ocorrência natural (fhbp) e métodos de uso das mesmas |
| AU2015222121B2 (en) | 2014-02-28 | 2018-01-18 | Glaxosmithkline Biologicals Sa | Modified meningococcal fHbp polypeptides |
| KR20150128099A (ko) | 2014-05-08 | 2015-11-18 | (주)엘지하우시스 | Pla 및 pha 혼합수지를 이용한 벽지 및 그 제조 방법 |
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| EP3169357B1 (en) * | 2014-07-17 | 2018-11-07 | GlaxoSmithKline Biologicals S.A. | Modified meningococcal fhbp polypeptides |
| KR102761870B1 (ko) | 2014-07-23 | 2025-02-05 | 칠드런즈 하스피틀 앤드 리써치 센터 앳 오클랜드 | 인자 h 결합 단백질 변이체 및 이의 사용 방법 |
| EP3607967A1 (en) * | 2018-08-09 | 2020-02-12 | GlaxoSmithKline Biologicals S.A. | Modified meningococcal fhbp polypeptides |
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2015
- 2015-07-22 KR KR1020237036853A patent/KR102761870B1/ko active Active
- 2015-07-22 CR CR20170020A patent/CR20170020A/es unknown
- 2015-07-22 AU AU2015292615A patent/AU2015292615B2/en active Active
- 2015-07-22 KR KR1020177004378A patent/KR102752259B1/ko active Active
- 2015-07-22 CA CA2955802A patent/CA2955802C/en active Active
- 2015-07-22 RU RU2017104742A patent/RU2714248C2/ru active
- 2015-07-22 EP EP15824545.6A patent/EP3172224B1/en active Active
- 2015-07-22 CN CN202411821930.3A patent/CN119613509A/zh active Pending
- 2015-07-22 MX MX2017001038A patent/MX382409B/es unknown
- 2015-07-22 EP EP22174947.6A patent/EP4074726A3/en active Pending
- 2015-07-22 JP JP2017503089A patent/JP6796057B2/ja active Active
- 2015-07-22 US US15/327,346 patent/US10266572B2/en active Active
- 2015-07-22 CN CN201580043542.XA patent/CN106715464B/zh active Active
- 2015-07-22 NZ NZ766005A patent/NZ766005A/en unknown
- 2015-07-22 BR BR112017001417-3A patent/BR112017001417B1/pt active IP Right Grant
- 2015-07-22 CN CN202110192031.1A patent/CN112851768A/zh active Pending
- 2015-07-22 WO PCT/US2015/041616 patent/WO2016014719A1/en not_active Ceased
- 2015-07-22 NZ NZ729206A patent/NZ729206A/en unknown
- 2015-07-22 CA CA3212723A patent/CA3212723A1/en active Pending
- 2015-07-22 ES ES15824545T patent/ES2922554T3/es active Active
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2017
- 2017-01-23 MX MX2023000204A patent/MX2023000204A/es unknown
- 2017-01-23 CO CONC2017/0000558A patent/CO2017000558A2/es unknown
- 2017-01-23 MX MX2021005373A patent/MX2021005373A/es unknown
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2019
- 2019-02-28 US US16/288,760 patent/US10487122B2/en active Active
- 2019-10-11 US US16/600,282 patent/US10995122B2/en active Active
- 2019-10-11 US US16/600,259 patent/US10836799B2/en active Active
- 2019-11-14 AU AU2019264600A patent/AU2019264600B2/en active Active
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2020
- 2020-09-23 JP JP2020158515A patent/JP7221917B2/ja active Active
- 2020-10-07 US US17/065,386 patent/US11834476B2/en active Active
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2021
- 2021-04-02 US US17/221,646 patent/US11673920B2/en active Active
- 2021-06-10 AU AU2021203828A patent/AU2021203828B2/en active Active
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2022
- 2022-11-10 JP JP2022180069A patent/JP7719046B2/ja active Active
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2023
- 2023-05-12 US US18/316,594 patent/US12129282B2/en active Active
- 2023-07-07 AU AU2023204391A patent/AU2023204391B2/en active Active
- 2023-10-24 US US18/493,141 patent/US12269849B2/en active Active
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2024
- 2024-09-19 US US18/890,476 patent/US20250136648A1/en active Pending
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2025
- 2025-01-14 US US19/020,854 patent/US20250154206A1/en active Pending
- 2025-04-22 AU AU2025202774A patent/AU2025202774A1/en active Pending
- 2025-04-24 JP JP2025071948A patent/JP2025108722A/ja active Pending
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