CR20220149A - Dosis para anticuerpos anti-triptasa - Google Patents

Dosis para anticuerpos anti-triptasa

Info

Publication number
CR20220149A
CR20220149A CR20220149A CR20220149A CR20220149A CR 20220149 A CR20220149 A CR 20220149A CR 20220149 A CR20220149 A CR 20220149A CR 20220149 A CR20220149 A CR 20220149A CR 20220149 A CR20220149 A CR 20220149A
Authority
CR
Costa Rica
Prior art keywords
tryptase
antibodies
dosing
tryptase antibodies
asthma
Prior art date
Application number
CR20220149A
Other languages
English (en)
Inventor
Sharon Marie Rymut
Joseph Haw-Ling Lin
Siddharth Sukumaran
Ryan Patrick Owen
Original Assignee
Genentech Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Genentech Inc filed Critical Genentech Inc
Publication of CR20220149A publication Critical patent/CR20220149A/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A61K39/39533—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
    • A61K39/3955—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against proteinaceous materials, e.g. enzymes, hormones, lymphokines
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/40—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against enzymes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/06—Antiasthmatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/545—Medicinal preparations containing antigens or antibodies characterised by the dose, timing or administration schedule
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/52—Constant or Fc region; Isotype
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
    • C07K2317/565—Complementarity determining region [CDR]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
    • C07K2317/92—Affinity (KD), association rate (Ka), dissociation rate (Kd) or EC50 value

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Pulmonology (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Immunology (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biochemistry (AREA)
  • Mycology (AREA)
  • Microbiology (AREA)
  • Endocrinology (AREA)
  • Epidemiology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

La presente invención incluye, entre otros, métodos para tratar a un paciente que tiene asma mediante administración de un anticuerpo anti-triptasa (por ejemplo, anticuerpo anti-triptasa beta) al paciente, anticuerpos anti-triptasa (por ejemplo, anticuerpos anti-triptasa beta) para usar en el tratamiento de asma, y usos de anticuerpos anti-triptasa (por ejemplo, anticuerpos anti-triptasa beta), por ejemplo, en la fabricación de medicamentos para tratar el asma.
CR20220149A 2019-09-20 2020-09-18 Dosis para anticuerpos anti-triptasa CR20220149A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201962903409P 2019-09-20 2019-09-20
PCT/US2020/051416 WO2021055694A1 (en) 2019-09-20 2020-09-18 Dosing for anti-tryptase antibodies

Publications (1)

Publication Number Publication Date
CR20220149A true CR20220149A (es) 2022-05-23

Family

ID=72709880

Family Applications (1)

Application Number Title Priority Date Filing Date
CR20220149A CR20220149A (es) 2019-09-20 2020-09-18 Dosis para anticuerpos anti-triptasa

Country Status (12)

Country Link
US (1) US20220348687A1 (es)
EP (1) EP4031580A1 (es)
JP (1) JP2022549218A (es)
KR (1) KR20220066295A (es)
CN (1) CN114423454A (es)
AU (1) AU2020348393A1 (es)
CA (1) CA3147179A1 (es)
CR (1) CR20220149A (es)
IL (1) IL291432A (es)
MX (1) MX2022003266A (es)
TW (1) TW202126699A (es)
WO (1) WO2021055694A1 (es)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2023019239A1 (en) * 2021-08-13 2023-02-16 Genentech, Inc. Dosing for anti-tryptase antibodies
WO2024216106A1 (en) * 2023-04-14 2024-10-17 Triveni Bio, Inc. Dual inhibitor trypsin antibodies and uses thereof

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Also Published As

Publication number Publication date
MX2022003266A (es) 2022-04-11
US20220348687A1 (en) 2022-11-03
AU2020348393A1 (en) 2022-02-24
IL291432A (en) 2022-05-01
JP2022549218A (ja) 2022-11-24
CA3147179A1 (en) 2021-03-25
CN114423454A (zh) 2022-04-29
EP4031580A1 (en) 2022-07-27
KR20220066295A (ko) 2022-05-24
WO2021055694A1 (en) 2021-03-25
TW202126699A (zh) 2021-07-16

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