CR7195A - Nuevos derivados de oxazolidinonas como antibacterianos - Google Patents
Nuevos derivados de oxazolidinonas como antibacterianosInfo
- Publication number
- CR7195A CR7195A CR7195A CR7195A CR7195A CR 7195 A CR7195 A CR 7195A CR 7195 A CR7195 A CR 7195A CR 7195 A CR7195 A CR 7195A CR 7195 A CR7195 A CR 7195A
- Authority
- CR
- Costa Rica
- Prior art keywords
- antibacterials
- oxazolidinones
- new derivatives
- derivatives
- new
- Prior art date
Links
- 229940088710 antibiotic agent Drugs 0.000 title abstract 2
- IZXIZTKNFFYFOF-UHFFFAOYSA-N 2-Oxazolidone Chemical class O=C1NCCO1 IZXIZTKNFFYFOF-UHFFFAOYSA-N 0.000 title 1
- 230000000844 anti-bacterial effect Effects 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 208000015181 infectious disease Diseases 0.000 abstract 1
- 238000004519 manufacturing process Methods 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 230000000813 microbial effect Effects 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D498/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
- C07D498/04—Ortho-condensed systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Oncology (AREA)
- Pharmacology & Pharmacy (AREA)
- Communicable Diseases (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Plural Heterocyclic Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Abstract
Proporciona nuevos derivados fluorquinologicos de oxazolidinosas de formula general (I) asi como procedimientos para su obtencion , las correspondientes composiciones farmaceuticas y su utilizacion para la fabricacion de un medicamento destinado al tratamiento de infecciones microbianas. Estos nuevos compuestos son utiles como antibacterianos.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| ES200101559A ES2186550B2 (es) | 2001-06-27 | 2001-06-27 | Nuevos derivados de oxazolidinonas como antibacterianos. |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CR7195A true CR7195A (es) | 2004-03-05 |
Family
ID=8498288
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CR7195A CR7195A (es) | 2001-06-27 | 2003-12-10 | Nuevos derivados de oxazolidinonas como antibacterianos |
Country Status (29)
| Country | Link |
|---|---|
| US (1) | US20040147545A1 (es) |
| EP (1) | EP1401834A1 (es) |
| JP (1) | JP2004521147A (es) |
| KR (1) | KR20040030712A (es) |
| CN (1) | CN1520412A (es) |
| AP (1) | AP2003002942A0 (es) |
| AR (1) | AR035254A1 (es) |
| BG (1) | BG108498A (es) |
| BR (1) | BR0210667A (es) |
| CA (1) | CA2450982A1 (es) |
| CO (1) | CO5540387A2 (es) |
| CR (1) | CR7195A (es) |
| CZ (1) | CZ2004101A3 (es) |
| EA (1) | EA200400086A1 (es) |
| EE (1) | EE200400004A (es) |
| ES (1) | ES2186550B2 (es) |
| HR (1) | HRP20031063A2 (es) |
| HU (1) | HUP0400370A2 (es) |
| IL (1) | IL159434A0 (es) |
| IS (1) | IS7088A (es) |
| MA (1) | MA27046A1 (es) |
| MX (1) | MXPA04000185A (es) |
| NO (1) | NO20035791L (es) |
| NZ (1) | NZ530206A (es) |
| OA (1) | OA12639A (es) |
| PE (1) | PE20030134A1 (es) |
| PL (1) | PL365476A1 (es) |
| SK (1) | SK572004A3 (es) |
| WO (1) | WO2003002560A1 (es) |
Families Citing this family (21)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2003031443A1 (en) * | 2001-10-04 | 2003-04-17 | Morphochem Aktiengesellschaft für kombinatorische Chemie | Dual actions antibiotics comprising a oxazoldinone and a quinolone or naphthyridinone moiety |
| ES2308171T3 (es) | 2003-04-30 | 2008-12-01 | Morphochem Aktiengesellschaft Fur Kombinatorische Chemie | Uso de antibioticos hibridos de oxazolidinona-quinolina para el tratamiento del antrax y de otras infecciones. |
| DE10340485B4 (de) | 2003-09-03 | 2015-05-13 | Morphochem AG Aktiengesellschaft für kombinatorische Chemie | Verfahren zur Herstellung von Oxazolidinon-Chinolon Hybriden |
| US7304050B2 (en) * | 2003-09-16 | 2007-12-04 | Pfizer Inc. | Antibacterial agents |
| WO2005051933A1 (en) * | 2003-11-28 | 2005-06-09 | Ranbaxy Laboratories Limited | An improved process for the synthesis of 4-(4-benzyloxy-carbonylamino-2-fluorophenyl)-piperazine-1-carboxylic acid tert-butyl ester, a key intermediate for oxazolidinone antimicrobials and compounds prepared thereby |
| US8158797B2 (en) | 2003-12-18 | 2012-04-17 | Morphochem Aktiengesellschaft Fur Kombinatorische Chemie | Oxazolidinone-quinolone hybrid antibiotics |
| CA2549675C (en) * | 2003-12-18 | 2012-11-20 | Morphochem Aktiengesellschaft Fur Kombinatorische Chemie | Oxazolidinone-quinolone hybrid antibiotics |
| EP1557416A1 (en) * | 2004-01-23 | 2005-07-27 | Morphochem Aktiengesellschaft Für Kombinatorische Chemie | Oxazolidinone-quinolone hybrid antibiotics |
| US20060105941A1 (en) * | 2004-11-12 | 2006-05-18 | Allergan, Inc. | Mixed antibiotic codrugs |
| EP2181994B1 (en) | 2006-03-31 | 2014-05-28 | Research Foundation Itsuu Laboratory | Antimicrobial compounds |
| US8530646B2 (en) | 2007-10-02 | 2013-09-10 | Research Foundation Itsuu Laboratory | Oxazolidinone derivative having 7-membered hetero ring |
| RU2527769C2 (ru) * | 2008-05-09 | 2014-09-10 | Актелион Фармасьютиклз Лтд | Производные 5-гидроксиметилоксазолидин-2-она для лечения бактериальных кишечных заболеваний |
| MX371037B (es) | 2013-05-28 | 2020-01-14 | Morphochem Aktiengesellschaft Fuer Komb Chemie | Antibacterianos híbridos de oxazolidinona-quinolona para el tratamiento parenteral o profilaxis de enfermedades bacterianas. |
| CN105246476B (zh) | 2013-05-28 | 2019-11-15 | 莫弗凯姆联合化学股份公司 | 含噁唑烷酮-喹诺酮的联合疗法在治疗细菌感染中的应用 |
| CN107286111B (zh) * | 2016-03-30 | 2020-06-19 | 广东赛法洛药业有限公司 | 一种噁唑烷酮化合物的制备方法 |
| CN107286182A (zh) * | 2016-04-12 | 2017-10-24 | 李靖 | 新型噁唑烷酮‑氟喹诺酮衍生物及用途 |
| US10087171B2 (en) | 2016-12-19 | 2018-10-02 | Actelion Pharmaceuticals Ltd | Crystalline forms of cadazolid |
| GB201708606D0 (en) | 2017-05-30 | 2017-07-12 | King S College London | Antibiotic resistance breakers |
| WO2019106693A1 (en) * | 2017-11-29 | 2019-06-06 | Bugworks Research India Pvt Ltd | Anti-bacterial heterocyclic compounds and their synthesis |
| CN111087409B (zh) * | 2018-10-24 | 2021-06-08 | 江阴安博生物医药有限公司 | 一种喹诺酮类化合物及其制备方法和应用 |
| CN117567455A (zh) * | 2019-12-11 | 2024-02-20 | 华创合成制药股份有限公司 | 一种新型噁唑烷酮类化合物及其合成方法和应用 |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SE444566B (sv) * | 1977-09-20 | 1986-04-21 | Bellon Labor Sa Roger | 7-dialkylamin-6-halogen-4-oxo-1,4-dihydrokinolin-3-karboxylsyra, forfarande for framstellning derav och farmaceutiskt preparat derav |
| EP0390215B1 (en) * | 1989-03-30 | 1995-06-07 | Wakunaga Seiyaku Kabushiki Kaisha | Quinolone derivatives and salts thereof, preparation process es thereof, and antibacterial agents containing the same |
| SK283420B6 (sk) * | 1992-05-08 | 2003-07-01 | Pharmacia & Upjohn Company | Antimikrobiálne oxazolidinóny obsahujúce substituované diazínové skupiny |
| MY115155A (en) | 1993-09-09 | 2003-04-30 | Upjohn Co | Substituted oxazine and thiazine oxazolidinone antimicrobials. |
| DK0788498T3 (da) * | 1994-10-26 | 2001-11-05 | Upjohn Co | Phenyloxazolidinoner med antimikrobiel virkning |
| HUP9901642A3 (en) * | 1996-01-31 | 2000-07-28 | Ube Ind Ltd Ube Shi | Remedies or preventives for aids |
| PT892792E (pt) * | 1996-04-11 | 2002-05-31 | Upjohn Co | Processo para a preparacao de oxazolidinonas |
| GB9614236D0 (en) * | 1996-07-06 | 1996-09-04 | Zeneca Ltd | Chemical compounds |
-
2001
- 2001-06-27 ES ES200101559A patent/ES2186550B2/es not_active Expired - Fee Related
-
2002
- 2002-06-24 CA CA002450982A patent/CA2450982A1/en not_active Abandoned
- 2002-06-24 SK SK57-2004A patent/SK572004A3/sk unknown
- 2002-06-24 AP APAP/P/2003/002942A patent/AP2003002942A0/en unknown
- 2002-06-24 OA OA1200300345A patent/OA12639A/en unknown
- 2002-06-24 KR KR10-2003-7017038A patent/KR20040030712A/ko not_active Withdrawn
- 2002-06-24 BR BR0210667-1A patent/BR0210667A/pt not_active Application Discontinuation
- 2002-06-24 EE EEP200400004A patent/EE200400004A/xx unknown
- 2002-06-24 JP JP2003508941A patent/JP2004521147A/ja active Pending
- 2002-06-24 US US10/469,283 patent/US20040147545A1/en not_active Abandoned
- 2002-06-24 HU HU0400370A patent/HUP0400370A2/hu unknown
- 2002-06-24 CN CNA028128524A patent/CN1520412A/zh active Pending
- 2002-06-24 EA EA200400086A patent/EA200400086A1/ru unknown
- 2002-06-24 EP EP02738497A patent/EP1401834A1/en not_active Withdrawn
- 2002-06-24 MX MXPA04000185A patent/MXPA04000185A/es unknown
- 2002-06-24 HR HR20031063A patent/HRP20031063A2/xx not_active Application Discontinuation
- 2002-06-24 PL PL02365476A patent/PL365476A1/xx not_active Application Discontinuation
- 2002-06-24 IL IL15943402A patent/IL159434A0/xx unknown
- 2002-06-24 NZ NZ530206A patent/NZ530206A/en unknown
- 2002-06-24 WO PCT/IB2002/002408 patent/WO2003002560A1/en not_active Ceased
- 2002-06-24 CZ CZ2004101A patent/CZ2004101A3/cs unknown
- 2002-06-26 PE PE2002000572A patent/PE20030134A1/es not_active Application Discontinuation
- 2002-06-26 AR ARP020102399A patent/AR035254A1/es not_active Application Discontinuation
-
2003
- 2003-12-10 CR CR7195A patent/CR7195A/es not_active Application Discontinuation
- 2003-12-22 NO NO20035791A patent/NO20035791L/no not_active Application Discontinuation
- 2003-12-22 BG BG108498A patent/BG108498A/xx unknown
- 2003-12-22 IS IS7088A patent/IS7088A/is unknown
- 2003-12-23 MA MA27460A patent/MA27046A1/fr unknown
- 2003-12-26 CO CO03112619A patent/CO5540387A2/es not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| NZ530206A (en) | 2005-07-29 |
| BR0210667A (pt) | 2004-10-05 |
| JP2004521147A (ja) | 2004-07-15 |
| EA200400086A1 (ru) | 2004-06-24 |
| WO2003002560A1 (en) | 2003-01-09 |
| OA12639A (en) | 2006-06-15 |
| ES2186550A1 (es) | 2003-05-01 |
| NO20035791L (no) | 2004-02-19 |
| PE20030134A1 (es) | 2003-04-04 |
| PL365476A1 (en) | 2005-01-10 |
| EE200400004A (et) | 2004-02-16 |
| BG108498A (en) | 2005-03-31 |
| ES2186550B2 (es) | 2003-11-16 |
| IS7088A (is) | 2003-12-22 |
| US20040147545A1 (en) | 2004-07-29 |
| CO5540387A2 (es) | 2005-07-29 |
| CA2450982A1 (en) | 2003-01-09 |
| MXPA04000185A (es) | 2004-03-18 |
| SK572004A3 (en) | 2004-08-03 |
| AR035254A1 (es) | 2004-05-05 |
| KR20040030712A (ko) | 2004-04-09 |
| EP1401834A1 (en) | 2004-03-31 |
| AP2003002942A0 (en) | 2003-12-24 |
| HRP20031063A2 (en) | 2004-04-30 |
| CZ2004101A3 (cs) | 2004-07-14 |
| MA27046A1 (fr) | 2004-12-20 |
| CN1520412A (zh) | 2004-08-11 |
| HUP0400370A2 (hu) | 2004-08-30 |
| IL159434A0 (en) | 2004-06-01 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FA | Abandonment or withdrawal (granting procedure) |