CR7777A - Microesferas antibioticas para el tratamiento de infecciones y osteomielitis - Google Patents
Microesferas antibioticas para el tratamiento de infecciones y osteomielitisInfo
- Publication number
- CR7777A CR7777A CR7777A CR7777A CR7777A CR 7777 A CR7777 A CR 7777A CR 7777 A CR7777 A CR 7777A CR 7777 A CR7777 A CR 7777A CR 7777 A CR7777 A CR 7777A
- Authority
- CR
- Costa Rica
- Prior art keywords
- antibiotic
- infections
- microspheres
- treatment
- osteomyelitis
- Prior art date
Links
- 230000003115 biocidal effect Effects 0.000 title abstract 4
- 239000004005 microsphere Substances 0.000 title abstract 4
- 208000015181 infectious disease Diseases 0.000 title abstract 3
- 206010031252 Osteomyelitis Diseases 0.000 title 1
- 239000002202 Polyethylene glycol Substances 0.000 abstract 2
- 229920001223 polyethylene glycol Polymers 0.000 abstract 2
- 239000003242 anti bacterial agent Substances 0.000 abstract 1
- 230000000844 anti-bacterial effect Effects 0.000 abstract 1
- 238000013270 controlled release Methods 0.000 abstract 1
- 230000002401 inhibitory effect Effects 0.000 abstract 1
- 230000002265 prevention Effects 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1605—Excipients; Inactive ingredients
- A61K9/1629—Organic macromolecular compounds
- A61K9/1641—Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, poloxamers
- A61K9/1647—Polyesters, e.g. poly(lactide-co-glycolide)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/54—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame
- A61K31/542—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame ortho- or peri-condensed with heterocyclic ring systems
- A61K31/545—Compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins, cefaclor, or cephalexine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7028—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages
- A61K31/7034—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a carbocyclic compound, e.g. phloridzin
- A61K31/7036—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a carbocyclic compound, e.g. phloridzin having at least one amino group directly attached to the carbocyclic ring, e.g. streptomycin, gentamycin, amikacin, validamycin, fortimicins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
- A61K9/0024—Solid, semi-solid or solidifying implants, which are implanted or injected in body tissue
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Dermatology (AREA)
- Physical Education & Sports Medicine (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Biomedical Technology (AREA)
- Neurosurgery (AREA)
- Molecular Biology (AREA)
- Oncology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Communicable Diseases (AREA)
- Rheumatology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US40850202P | 2002-09-05 | 2002-09-05 | |
| US40849602P | 2002-09-05 | 2002-09-05 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CR7777A true CR7777A (es) | 2008-10-08 |
Family
ID=31981593
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CR7777A CR7777A (es) | 2002-09-05 | 2005-03-31 | Microesferas antibioticas para el tratamiento de infecciones y osteomielitis |
Country Status (11)
| Country | Link |
|---|---|
| US (1) | US20040131681A1 (es) |
| EP (1) | EP1549246B1 (es) |
| AT (1) | ATE555748T1 (es) |
| AU (1) | AU2003272284B2 (es) |
| CA (1) | CA2497973C (es) |
| CR (1) | CR7777A (es) |
| ES (1) | ES2388623T3 (es) |
| MX (1) | MXPA05002589A (es) |
| NO (1) | NO20051665L (es) |
| NZ (1) | NZ539166A (es) |
| WO (1) | WO2004022000A2 (es) |
Families Citing this family (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20040260398A1 (en) * | 2003-02-10 | 2004-12-23 | Kelman David C. | Resorbable devices |
| GB0329654D0 (en) | 2003-12-23 | 2004-01-28 | Smith & Nephew | Tunable segmented polyacetal |
| CA2619571A1 (en) * | 2005-08-18 | 2007-02-22 | Smith & Nephew, Plc | High strength devices and composites |
| DE102005040429A1 (de) * | 2005-08-25 | 2007-03-01 | Heraeus Kulzer Gmbh | Wirkstofffreisetzungssystem und seine Verwendung |
| CA2679365C (en) | 2006-11-30 | 2016-05-03 | Smith & Nephew, Inc. | Fiber reinforced composite material |
| EP2142353A1 (en) | 2007-04-18 | 2010-01-13 | Smith & Nephew PLC | Expansion moulding of shape memory polymers |
| JP5680957B2 (ja) | 2007-04-19 | 2015-03-04 | スミス アンド ネフュー インコーポレーテッドＳｍｉｔｈ ＆ Ｎｅｐｈｅｗ，Ｉｎｃ． | グラフト固定 |
| ATE547129T1 (de) | 2007-04-19 | 2012-03-15 | Smith & Nephew Inc | Multimodale formgedächtnis-polymere |
| GB0814302D0 (en) | 2008-08-05 | 2008-10-01 | Coretherapix Slu | Compounds and methods |
| EP2523634A4 (en) * | 2010-01-15 | 2014-08-06 | Univ Rice William M | COMBINED ROOM MANAGEMENT AND BONE REGENERATION SYSTEM FOR THE RECONSTRUCTION OF LARGE-BONE DAMAGE |
| WO2014062839A1 (en) | 2012-10-16 | 2014-04-24 | Surmodics, Inc. | Wound packing device and methods |
| US10201457B2 (en) | 2014-08-01 | 2019-02-12 | Surmodics, Inc. | Wound packing device with nanotextured surface |
| US10029031B2 (en) * | 2015-10-28 | 2018-07-24 | Warsaw Orthopedic, Inc. | Bone void filler having sustained therapeutic agent release |
Family Cites Families (29)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3236355A (en) * | 1961-12-21 | 1966-02-22 | Pitney Bowes Inc | Mail handling device |
| US6309669B1 (en) * | 1984-03-16 | 2001-10-30 | The United States Of America As Represented By The Secretary Of The Army | Therapeutic treatment and prevention of infections with a bioactive materials encapsulated within a biodegradable-biocompatible polymeric matrix |
| US6410056B1 (en) * | 1984-03-16 | 2002-06-25 | The United States Of America As Represented By The Secretary Of The Army | Chemotherapeutic treatment of bacterial infections with an antibiotic encapsulated within a biodegradable polymeric matrix |
| US6217911B1 (en) * | 1995-05-22 | 2001-04-17 | The United States Of America As Represented By The Secretary Of The Army | sustained release non-steroidal, anti-inflammatory and lidocaine PLGA microspheres |
| US5718921A (en) * | 1987-03-13 | 1998-02-17 | Massachusetts Institute Of Technology | Microspheres comprising polymer and drug dispersed there within |
| US5690954A (en) * | 1987-05-22 | 1997-11-25 | Danbiosyst Uk Limited | Enhanced uptake drug delivery system having microspheres containing an active drug and a bioavailability improving material |
| US5236355A (en) * | 1988-12-22 | 1993-08-17 | American Cyanamid Company | Apparatus for the treatment of periodontal disease |
| JP3116311B2 (ja) * | 1990-06-13 | 2000-12-11 | エーザイ株式会社 | マイクロスフィアの製法 |
| US6197346B1 (en) * | 1992-04-24 | 2001-03-06 | Brown Universtiy Research Foundation | Bioadhesive microspheres and their use as drug delivery and imaging systems |
| FR2692147B1 (fr) * | 1992-06-15 | 1995-02-24 | Centre Nat Rech Scient | Microsphères en polymère biorésorbable exemptes de tensioactif, leur préparation et leur application comme médicament. |
| US5700485A (en) * | 1992-09-10 | 1997-12-23 | Children's Medical Center Corporation | Prolonged nerve blockade by the combination of local anesthetic and glucocorticoid |
| US5569468A (en) * | 1994-02-17 | 1996-10-29 | Modi; Pankaj | Vaccine delivery system for immunization, using biodegradable polymer microspheres |
| GB9406094D0 (en) * | 1994-03-28 | 1994-05-18 | Univ Nottingham And University | Polymer microspheres and a method of production thereof |
| FR2718642B1 (fr) * | 1994-04-15 | 1996-07-12 | Pf Medicament | Microsphères biodégradables à libération contrôlée et leur procédé de préparation. |
| GB9412273D0 (en) * | 1994-06-18 | 1994-08-10 | Univ Nottingham | Administration means |
| US5599889A (en) * | 1994-08-16 | 1997-02-04 | Stoever; Harald D. H. | Method of forming polymer microspheres |
| US6117455A (en) * | 1994-09-30 | 2000-09-12 | Takeda Chemical Industries, Ltd. | Sustained-release microcapsule of amorphous water-soluble pharmaceutical active agent |
| JP2909418B2 (ja) * | 1995-09-18 | 1999-06-23 | 株式会社資生堂 | 薬物の遅延放出型マイクロスフイア |
| DE19545257A1 (de) * | 1995-11-24 | 1997-06-19 | Schering Ag | Verfahren zur Herstellung von morphologisch einheitlichen Mikrokapseln sowie nach diesem Verfahren hergestellte Mikrokapseln |
| US5578650A (en) * | 1995-12-01 | 1996-11-26 | Minnesota Mining And Manufacturing Company | Methods of preparing hollow acrylate polymer microspheres |
| KR0162872B1 (ko) * | 1996-04-01 | 1998-12-01 | 김은영 | 용매추출법을 이용한 생분해성 고분자 미립구의 개선된 제조방법 및 이를 이용한 국소염증 질환 치료용 미립구의 제조방법 |
| US5858531A (en) * | 1996-10-24 | 1999-01-12 | Bio Syntech | Method for preparation of polymer microparticles free of organic solvent traces |
| GB9710699D0 (en) * | 1997-05-24 | 1997-07-16 | Danbiosyst Uk | Gastro-retentive controlled release system |
| JP2000511941A (ja) * | 1997-07-02 | 2000-09-12 | ユーロ−セルティーク エス．エイ． | 関節間隙および身体間隙における持効性麻酔 |
| US6153210A (en) * | 1997-08-14 | 2000-11-28 | Periodontix, Inc. | Use of locally delivered metal ions for treatment of periodontal disease |
| US6841617B2 (en) * | 2000-09-28 | 2005-01-11 | Battelle Memorial Institute | Thermogelling biodegradable aqueous polymer solution |
| HUP0201626A3 (en) * | 1999-06-04 | 2004-05-28 | Alza Corp Mountain View | Implantable gel compositions and method of manufacture |
| US6461631B1 (en) * | 1999-11-16 | 2002-10-08 | Atrix Laboratories, Inc. | Biodegradable polymer composition |
| KR100446101B1 (ko) * | 2000-12-07 | 2004-08-30 | 주식회사 삼양사 | 수난용성 약물의 서방성 제형 조성물 |
-
2003
- 2003-09-05 MX MXPA05002589A patent/MXPA05002589A/es active IP Right Grant
- 2003-09-05 ES ES03754460T patent/ES2388623T3/es not_active Expired - Lifetime
- 2003-09-05 NZ NZ539166A patent/NZ539166A/en not_active IP Right Cessation
- 2003-09-05 US US10/655,639 patent/US20040131681A1/en not_active Abandoned
- 2003-09-05 CA CA2497973A patent/CA2497973C/en not_active Expired - Lifetime
- 2003-09-05 WO PCT/US2003/028010 patent/WO2004022000A2/en not_active Ceased
- 2003-09-05 EP EP03754460A patent/EP1549246B1/en not_active Expired - Lifetime
- 2003-09-05 AU AU2003272284A patent/AU2003272284B2/en not_active Expired
- 2003-09-05 AT AT03754460T patent/ATE555748T1/de active
-
2005
- 2005-03-31 CR CR7777A patent/CR7777A/es not_active Application Discontinuation
- 2005-04-04 NO NO20051665A patent/NO20051665L/no not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| MXPA05002589A (es) | 2005-09-20 |
| CA2497973A1 (en) | 2004-03-18 |
| EP1549246B1 (en) | 2012-05-02 |
| AU2003272284B2 (en) | 2009-03-05 |
| WO2004022000A3 (en) | 2004-06-10 |
| CA2497973C (en) | 2012-11-06 |
| NO20051665L (no) | 2005-05-31 |
| EP1549246A4 (en) | 2008-11-05 |
| ATE555748T1 (de) | 2012-05-15 |
| WO2004022000A2 (en) | 2004-03-18 |
| NZ539166A (en) | 2008-03-28 |
| EP1549246A2 (en) | 2005-07-06 |
| US20040131681A1 (en) | 2004-07-08 |
| ES2388623T3 (es) | 2012-10-17 |
| AU2003272284A1 (en) | 2004-03-29 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FA | Abandonment or withdrawal (granting procedure) |