CR7926A - Inhibidores peptidicos de toxinas derivadas de la ll-37 - Google Patents

Inhibidores peptidicos de toxinas derivadas de la ll-37

Info

Publication number
CR7926A
CR7926A CR7926A CR7926A CR7926A CR 7926 A CR7926 A CR 7926A CR 7926 A CR7926 A CR 7926A CR 7926 A CR7926 A CR 7926A CR 7926 A CR7926 A CR 7926A
Authority
CR
Costa Rica
Prior art keywords
inhibitors derived
toxin inhibitors
compounds
toxins
peptidic
Prior art date
Application number
CR7926A
Other languages
English (en)
Inventor
Jakobus Grote Johannes
Wouter Drijfohut Jan
Original Assignee
Academisch Ziekenhuis Leiden
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Academisch Ziekenhuis Leiden filed Critical Academisch Ziekenhuis Leiden
Publication of CR7926A publication Critical patent/CR7926A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
    • C07K14/4723—Cationic antimicrobial peptides, e.g. defensins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/10—Antimycotics
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Toxicology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Gastroenterology & Hepatology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Wood Science & Technology (AREA)
  • Epidemiology (AREA)
  • Physics & Mathematics (AREA)
  • Plant Pathology (AREA)
  • Microbiology (AREA)
  • Pulmonology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)

Abstract

La presente invencion se refiere a un grupo de compuestos peptidos que tienen afinidad por toxinas y especialmente por toxinas bacterianas, tales como el lipopolisacarido o el acido lipoteicoico. Estos compuestos pueden inhibir o neutralizar las toxinas. Ademas, la presente invencion se refiere al uso de estos compuestos como agentes terapeuticos o de diagnostico.
CR7926A 2003-01-28 2005-07-28 Inhibidores peptidicos de toxinas derivadas de la ll-37 CR7926A (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP03075274 2003-01-28

Publications (1)

Publication Number Publication Date
CR7926A true CR7926A (es) 2006-02-07

Family

ID=32798944

Family Applications (1)

Application Number Title Priority Date Filing Date
CR7926A CR7926A (es) 2003-01-28 2005-07-28 Inhibidores peptidicos de toxinas derivadas de la ll-37

Country Status (19)

Country Link
US (1) US7807617B2 (es)
EP (1) EP1587830B1 (es)
JP (1) JP4471968B2 (es)
KR (1) KR100856819B1 (es)
CN (1) CN1798764B (es)
AT (1) ATE435870T1 (es)
AU (1) AU2004207118B2 (es)
BR (1) BRPI0407022A (es)
CA (1) CA2514584C (es)
CR (1) CR7926A (es)
DE (1) DE602004021901D1 (es)
DK (1) DK1587830T3 (es)
ES (1) ES2328571T3 (es)
MX (1) MXPA05008080A (es)
NZ (1) NZ541657A (es)
PT (1) PT1587830E (es)
RU (1) RU2346950C2 (es)
WO (1) WO2004067563A1 (es)
ZA (1) ZA200506411B (es)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1621205A1 (en) * 2004-07-28 2006-02-01 OctoPlus Technologies B.V. Antimicrobial peptides derived from CAP18
US7465784B2 (en) * 2006-10-26 2008-12-16 Board Of Regents Of The University Of Nebraska Antimicrobial peptides and methods of identifying the same
WO2009015336A2 (en) 2007-07-25 2009-01-29 Biolex Therapeutics, Inc. Controlled release interferon drug products and treatment of hcv infection using same
EP2538964A4 (en) * 2010-02-25 2013-07-31 Univ Manitoba MODULATION OF CYTOKININDUCED CHRONIC INFLAMMATORY REACTIONS
US10723764B2 (en) 2011-11-21 2020-07-28 Board Of Regents Of The University Of Nebraska Anti-microbial peptides and methods of use thereof
US9580472B2 (en) 2011-11-21 2017-02-28 Board Of Regents Of The University Of Nebraska Anti-microbial peptides and methods of use thereof
AR092872A1 (es) * 2012-09-17 2015-05-06 Madrigal Pharmaceuticals Inc Metodo para sintetizar analogos de la hormona tiroidea y polimorfos de los mismos
BR112017009764A2 (pt) 2014-11-10 2018-02-20 Hoffmann La Roche anticorpos biespecíficos e métodos de uso em oftalmologia
RU2584089C1 (ru) * 2015-06-15 2016-05-20 Государственное Бюджетное Образовательное Учреждение Высшего Профессионального Образования "Саратовский Государственный Медицинский Университет Имени В.И. Разумовского" Министерства Здравоохранения Российской Федерации Способ снижения летального эффекта бактериального липополисахарида in vitro
CN105859867A (zh) * 2016-05-30 2016-08-17 黄石市中心医院 一种人源抗菌肽ll-37突变体及其应用
CN108892719B (zh) * 2018-07-09 2021-07-30 珠海中科先进技术研究院有限公司 一种新型人源抗菌肽ll-37衍生物及其应用
WO2021143745A1 (zh) * 2020-01-14 2021-07-22 中国科学院上海药物研究所 一种长效罗哌卡因药物组合物及其制备方法和用途
CN113116811A (zh) * 2020-01-14 2021-07-16 中国科学院上海药物研究所 可注射长效镇痛药物组合物及其制备方法和用途
WO2024223883A1 (en) 2023-04-26 2024-10-31 Karl-Franzens-Universität Graz Peptides for cancer therapy
WO2024223887A1 (en) 2023-04-26 2024-10-31 Karl-Franzens-Universität Graz Peptides for antimicrobial therapy
CN118754950B (zh) * 2024-06-07 2025-03-07 扬州大学 一种抗菌衍生肽及其组合物和应用

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6103888A (en) * 1992-07-17 2000-08-15 Panorama Research, Inc. Mammalian cationic proteins having lipopolysaccharide binding and anti-coagulant activity
US5681824A (en) * 1995-06-05 1997-10-28 Eisai Co., Ltd. Substituted liposaccharides useful in the treatment and prevention of endotoxemia
JP4037525B2 (ja) * 1998-03-25 2008-01-23 生化学工業株式会社 新規抗菌性ペプチド

Also Published As

Publication number Publication date
RU2005127076A (ru) 2006-01-20
JP2007528696A (ja) 2007-10-18
WO2004067563A1 (en) 2004-08-12
BRPI0407022A (pt) 2006-01-10
ES2328571T3 (es) 2009-11-16
WO2004067563A8 (en) 2004-12-02
AU2004207118A1 (en) 2004-08-12
CA2514584C (en) 2012-05-29
US20060223755A1 (en) 2006-10-05
PT1587830E (pt) 2009-09-23
RU2346950C2 (ru) 2009-02-20
DK1587830T3 (da) 2009-10-26
JP4471968B2 (ja) 2010-06-02
US7807617B2 (en) 2010-10-05
KR100856819B1 (ko) 2008-09-05
MXPA05008080A (es) 2006-02-08
HK1088613A1 (zh) 2006-11-10
NZ541657A (en) 2009-01-31
DE602004021901D1 (de) 2009-08-20
AU2004207118B2 (en) 2009-12-17
EP1587830B1 (en) 2009-07-08
CN1798764B (zh) 2010-05-12
ZA200506411B (en) 2006-04-26
CA2514584A1 (en) 2004-08-12
KR20060012261A (ko) 2006-02-07
ATE435870T1 (de) 2009-07-15
EP1587830A1 (en) 2005-10-26
CN1798764A (zh) 2006-07-05

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Legal Events

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