CR8255A - Tienopirazoles - Google Patents

Tienopirazoles

Info

Publication number
CR8255A
CR8255A CR8255A CR8255A CR8255A CR 8255 A CR8255 A CR 8255A CR 8255 A CR8255 A CR 8255A CR 8255 A CR8255 A CR 8255A CR 8255 A CR8255 A CR 8255A
Authority
CR
Costa Rica
Prior art keywords
tienopirazoles
tienopyrazoles
itk
inhibition
modulated
Prior art date
Application number
CR8255A
Other languages
English (en)
Inventor
Gerard Jurcak John
Barrague Matthieu
Alan Gillespy Timothy
Louis Edwards Michael
Yon Musick Kwon
Marvin Weintraub Philip
Du Yan
Dharanioragada Ramalinga
Ahmed Parkar Ashfaq
Original Assignee
Aventis Pharma Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Aventis Pharma Inc filed Critical Aventis Pharma Inc
Publication of CR8255A publication Critical patent/CR8255A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
    • C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D495/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/06—Antiasthmatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pulmonology (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)

Abstract

Tienopirazoles, su preparacion, composiciones farmaceuticas que comprenden estos compuestos, y sus usos farmaceuticos en el tratamiento de estados de enfermedad capaces de ser modulados por la inhibicion de las proteina quinasas, en particular la tirosina quinasa inducible por interleuquina-2 (ITK)
CR8255A 2003-09-08 2006-02-23 Tienopirazoles CR8255A (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US50115903P 2003-09-08 2003-09-08

Publications (1)

Publication Number Publication Date
CR8255A true CR8255A (es) 2006-07-14

Family

ID=34312256

Family Applications (1)

Application Number Title Priority Date Filing Date
CR8255A CR8255A (es) 2003-09-08 2006-02-23 Tienopirazoles

Country Status (29)

Country Link
US (2) US7518000B2 (es)
JP (1) JP4879739B2 (es)
KR (1) KR20060069490A (es)
CN (1) CN100398545C (es)
AT (1) ATE468341T1 (es)
AU (1) AU2004272507B2 (es)
BR (1) BRPI0414215A (es)
CA (1) CA2538032C (es)
CR (1) CR8255A (es)
DE (1) DE602004027288D1 (es)
DK (1) DK1682553T3 (es)
EC (1) ECSP066411A (es)
ES (1) ES2345257T3 (es)
HR (1) HRP20100398T1 (es)
IL (1) IL173916A (es)
MA (1) MA28038A1 (es)
ME (1) MEP20908A (es)
MX (1) MXPA06001827A (es)
MY (1) MY144339A (es)
NO (1) NO20061626L (es)
NZ (1) NZ545421A (es)
OA (1) OA13252A (es)
PT (1) PT1682553E (es)
RS (2) RS51846B (es)
RU (1) RU2358978C2 (es)
TN (1) TNSN06058A1 (es)
TW (1) TWI352705B (es)
WO (1) WO2005026175A1 (es)
ZA (1) ZA200601947B (es)

Families Citing this family (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2006101454A1 (en) * 2005-03-21 2006-09-28 S*Bio Pte Ltd Benzothiophene derivatives: preparation and pharmaceutical applications
WO2007076228A2 (en) * 2005-12-20 2007-07-05 Boehringer Ingelheim International Gmbh 2-(ih-thieno [3,2-c] pyrazol-3yl)-ih-indole derivatives and related compounds as tec kinase inhibitors for the treatment of inflammations and immunological disorders
EP2151433A1 (en) 2008-08-05 2010-02-10 Institut Pasteur Alkoxypyrazoles and the process for their preparation
EP2151434A1 (en) 2008-08-05 2010-02-10 Institut Pasteur Alkoxypyrazoles and the process for their preparation
US8299070B2 (en) * 2009-11-25 2012-10-30 Japan Tobacco Inc. Indole compounds and pharmaceutical use thereof
US20130158066A1 (en) * 2011-12-20 2013-06-20 Hoffmann-La Roche Inc. 4-azaindole inhibitors of crac
WO2013153539A1 (en) 2012-04-13 2013-10-17 Glenmark Pharmaceuticals S.A. Tricyclic compounds as tec kinase inhibitors
CN103467481B (zh) * 2012-06-07 2016-08-31 上海汇伦生命科技有限公司 二氢吡啶类化合物、其组合物、制备方法和用途
TW201414734A (zh) 2012-07-10 2014-04-16 Takeda Pharmaceutical 氮雜吲哚衍生物
WO2014041518A1 (en) * 2012-09-14 2014-03-20 Glenmark Pharmaceuticals S.A. Thienopyrrole derivatives as itk inhibitors
CN103720694A (zh) * 2012-10-11 2014-04-16 韩冰 一类治疗脑性瘫痪的化合物及其用途
CN103772391A (zh) * 2012-10-23 2014-05-07 杨子娇 一类治疗房角狭窄的化合物及其用途
KR101571590B1 (ko) * 2012-11-21 2015-11-25 주식회사 두산 유기 화합물 및 이를 이용하는 유기 전계 발광 소자
JP2016538270A (ja) 2013-10-25 2016-12-08 ファーマサイクリックス エルエルシー 移植片対宿主病を処置し予防する方法
WO2015106012A1 (en) 2014-01-09 2015-07-16 Takeda Pharmaceutical Company Limited Azaindole derivatives
WO2016010108A1 (ja) * 2014-07-18 2016-01-21 塩野義製薬株式会社 含窒素複素環誘導体およびそれらを含有する医薬組成物
MA45973A (fr) 2015-08-31 2019-06-26 Pharmacyclics Llc Combinaisons d'inhibiteurs de btk pour le traitement du myélome multiple
JP2019532997A (ja) 2016-11-03 2019-11-14 ジュノー セラピューティクス インコーポレイテッド Ｔ細胞療法とｂｔｋ阻害剤との併用療法
KR20210044736A (ko) 2018-05-03 2021-04-23 주노 쎄러퓨티크스 인코퍼레이티드 키메라 항원 수용체(ｃａｒ) ｔ세포 요법과 키나제 억제제의 조합요법
WO2023139248A1 (en) * 2022-01-21 2023-07-27 Ecole Polytechnique Federale De Lausanne (Epfl) Inhibitors of acyl protein thioesterases against microbial infections
WO2023220655A1 (en) 2022-05-11 2023-11-16 Celgene Corporation Methods to overcome drug resistance by re-sensitizing cancer cells to treatment with a prior therapy via treatment with a t cell therapy
WO2024123175A1 (en) 2022-12-06 2024-06-13 Erasmus University Medical Center Rotterdam Compositions for treating immune checkpoint blockade therapy resistant cancers

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5654307A (en) * 1994-01-25 1997-08-05 Warner-Lambert Company Bicyclic compounds capable of inhibiting tyrosine kinases of the epidermal growth factor receptor family
US6462036B1 (en) * 1998-11-06 2002-10-08 Basf Aktiengesellschaft Tricyclic pyrazole derivatives
US6297238B1 (en) * 1999-04-06 2001-10-02 Basf Aktiengesellschaft Therapeutic agents
DK1194425T3 (da) * 1999-06-23 2005-11-21 Aventis Pharma Gmbh Substituerede benzimidazoler
YU54202A (sh) * 2000-01-18 2006-01-16 Agouron Pharmaceuticals Inc. Jedinjenja indazola, farmaceutske smeše i postupci za stimulisanje i inhibiranje ćelijske proliferacije
WO2003024969A1 (en) * 2001-09-14 2003-03-27 Merck & Co., Inc. Tyrosine kinase inhibitors
FR2831536A1 (fr) * 2001-10-26 2003-05-02 Aventis Pharma Sa Nouveaux derives de benzimidazoles, leur procede de preparation, leur application a titre de medicament, compositions pharmaceutiques et nouvelle utilisation notamment comme inhibiteurs de kdr
BR0213562A (pt) * 2001-10-26 2004-08-31 Aventis Pharma Inc Benzimidazóis e análogos e seu uso como inibidores de cinases de proteìna

Also Published As

Publication number Publication date
MXPA06001827A (es) 2006-05-31
RS51846B (sr) 2012-02-29
ATE468341T1 (de) 2010-06-15
RU2006111470A (ru) 2007-10-27
BRPI0414215A (pt) 2006-11-07
CN100398545C (zh) 2008-07-02
US20070254937A1 (en) 2007-11-01
AU2004272507B2 (en) 2011-05-12
DK1682553T3 (da) 2010-08-23
CN1849322A (zh) 2006-10-18
US7928231B2 (en) 2011-04-19
TW200519118A (en) 2005-06-16
AU2004272507A1 (en) 2005-03-24
MEP20908A (en) 2010-06-10
ES2345257T3 (es) 2010-09-20
US20100056514A1 (en) 2010-03-04
NZ545421A (en) 2010-03-26
ECSP066411A (es) 2006-09-18
CA2538032A1 (en) 2005-03-24
JP2007505038A (ja) 2007-03-08
IL173916A (en) 2011-07-31
OA13252A (en) 2007-01-31
HRP20100398T1 (hr) 2010-09-30
JP4879739B2 (ja) 2012-02-22
HK1095587A1 (zh) 2007-05-11
KR20060069490A (ko) 2006-06-21
NO20061626L (no) 2006-04-10
WO2005026175A1 (en) 2005-03-24
DE602004027288D1 (en) 2010-07-01
ZA200601947B (en) 2007-05-30
TNSN06058A1 (en) 2007-10-03
RS20060162A (sr) 2008-06-05
TWI352705B (en) 2011-11-21
RU2358978C2 (ru) 2009-06-20
MY144339A (en) 2011-08-29
PT1682553E (pt) 2010-07-29
CA2538032C (en) 2011-01-11
MA28038A1 (fr) 2006-07-03
IL173916A0 (en) 2006-07-05
US7518000B2 (en) 2009-04-14

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Legal Events

Date Code Title Description
FA Abandonment or withdrawal (granting procedure)