CR8755A - Derivado de quinolina fusionada y uso del mismo - Google Patents
Derivado de quinolina fusionada y uso del mismoInfo
- Publication number
- CR8755A CR8755A CR8755A CR8755A CR8755A CR 8755 A CR8755 A CR 8755A CR 8755 A CR8755 A CR 8755A CR 8755 A CR8755 A CR 8755A CR 8755 A CR8755 A CR 8755A
- Authority
- CR
- Costa Rica
- Prior art keywords
- substituent
- optionally
- group optionally
- acyl
- hydrogen atom
- Prior art date
Links
- UABNNDYJUIQZQZ-UHFFFAOYSA-N 1-(4-chlorobenzoyl)-2-(3,4-dimethoxyphenyl)-2,3a-dihydro-1h-pyrrolo[1,2-a]quinoline-3,3-dicarbonitrile Chemical compound C1=C(OC)C(OC)=CC=C1C1C(C#N)(C#N)C(C=CC=2C3=CC=CC=2)N3C1C(=O)C1=CC=C(Cl)C=C1 UABNNDYJUIQZQZ-UHFFFAOYSA-N 0.000 title 1
- 125000001424 substituent group Chemical group 0.000 abstract 24
- 125000002252 acyl group Chemical group 0.000 abstract 5
- 125000001183 hydrocarbyl group Chemical group 0.000 abstract 5
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 5
- 125000002924 primary amino group Chemical group [H]N([H])* 0.000 abstract 5
- 125000000623 heterocyclic group Chemical group 0.000 abstract 4
- 150000003573 thiols Chemical class 0.000 abstract 4
- 125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 3
- 208000020401 Depressive disease Diseases 0.000 abstract 1
- 125000005090 alkenylcarbonyl group Chemical group 0.000 abstract 1
- 125000004448 alkyl carbonyl group Chemical group 0.000 abstract 1
- 125000004432 carbon atom Chemical group C* 0.000 abstract 1
- 239000003795 chemical substances by application Substances 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 125000004093 cyano group Chemical group *C#N 0.000 abstract 1
- 125000004122 cyclic group Chemical group 0.000 abstract 1
- 125000000753 cycloalkyl group Chemical group 0.000 abstract 1
- 229910052736 halogen Inorganic materials 0.000 abstract 1
- 150000002367 halogens Chemical class 0.000 abstract 1
- 208000024714 major depressive disease Diseases 0.000 abstract 1
- 201000003995 melancholia Diseases 0.000 abstract 1
- 125000000449 nitro group Chemical group [O-][N+](*)=O 0.000 abstract 1
- 238000011321 prophylaxis Methods 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 238000011282 treatment Methods 0.000 abstract 1
Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
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Landscapes
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biomedical Technology (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Pulmonology (AREA)
- Immunology (AREA)
- Virology (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Physical Education & Sports Medicine (AREA)
- Pain & Pain Management (AREA)
- Urology & Nephrology (AREA)
- Rheumatology (AREA)
- Dermatology (AREA)
- Psychiatry (AREA)
- Hospice & Palliative Care (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Otolaryngology (AREA)
- Molecular Biology (AREA)
- Psychology (AREA)
- Ophthalmology & Optometry (AREA)
- Hematology (AREA)
- Diabetes (AREA)
- Anesthesiology (AREA)
Abstract
Se dirige en la provision de un derivado de quinolina que tiene una accion antagonista del receptor de neuroquinina 2(NK2) y se refiere a un compuesto representado por la formula (I)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2004134705 | 2004-04-28 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CR8755A true CR8755A (es) | 2007-01-17 |
Family
ID=34966886
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CR8755A CR8755A (es) | 2004-04-28 | 2006-11-17 | Derivado de quinolina fusionada y uso del mismo |
Country Status (27)
| Country | Link |
|---|---|
| US (4) | US7592453B2 (es) |
| EP (2) | EP2080760A1 (es) |
| JP (2) | JP4361566B2 (es) |
| KR (1) | KR20070015598A (es) |
| CN (1) | CN1976932A (es) |
| AT (1) | ATE416176T1 (es) |
| AU (1) | AU2005238388B2 (es) |
| BR (1) | BRPI0510365A (es) |
| CA (1) | CA2565018A1 (es) |
| CR (1) | CR8755A (es) |
| CY (1) | CY1109222T1 (es) |
| DE (1) | DE602005011424D1 (es) |
| DK (1) | DK1740584T5 (es) |
| ES (1) | ES2318483T4 (es) |
| HR (1) | HRP20090121T5 (es) |
| MX (1) | MXPA06012323A (es) |
| MY (1) | MY143370A (es) |
| NO (1) | NO20065494L (es) |
| NZ (1) | NZ550983A (es) |
| PL (1) | PL1740584T3 (es) |
| PT (1) | PT1740584E (es) |
| RS (1) | RS50756B (es) |
| RU (1) | RU2384571C2 (es) |
| SI (1) | SI1740584T1 (es) |
| TW (1) | TW200540155A (es) |
| WO (1) | WO2005105802A1 (es) |
| ZA (1) | ZA200609261B (es) |
Families Citing this family (40)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| RU2384571C2 (ru) * | 2004-04-28 | 2010-03-20 | Такеда Фармасьютикал Компани Лимитед | Конденсированное хинолиновое производное и его применение |
| MXPA06014909A (es) | 2004-06-18 | 2007-02-28 | Chiron Corp | Derivados de n-(1-(1-bencil -4-fenil-1h -imidazol -2-il)-2, 2-dimetilpropil) benzamida y compuestos relacionados como inhibidores de proteina de huso de cinesina (ksp) para el tratamiento del cancer. |
| WO2006045119A2 (en) | 2004-10-20 | 2006-04-27 | The Regents Of The University Of California | Improved inhibitors for the soluble epoxide hydrolase |
| DE102005027170A1 (de) * | 2005-06-13 | 2006-12-14 | Merck Patent Gmbh | Substituierte Tetrahydrochinoline |
| GB0522715D0 (en) | 2005-11-08 | 2005-12-14 | Helperby Therapeutics Ltd | New use |
| WO2007074491A1 (en) * | 2005-12-28 | 2007-07-05 | Universita Degli Studi Di Siena | HETEROTRICYCLIC AMIDE DERIVATIVES AS NEUROKININ-l (NKl) RECEPTOR LIGANDS |
| JP4509080B2 (ja) * | 2006-09-28 | 2010-07-21 | 信越化学工業株式会社 | シルセスキオキサン系化合物混合物及び加水分解性シラン化合物、その製造方法及びそれを用いたレジスト組成物並びにパターン形成方法及び基板の加工方法 |
| US8450336B2 (en) | 2006-12-14 | 2013-05-28 | Nps Pharmaceuticals, Inc | Use of D-serine derivatives for the treatment of anxiety disorders |
| CA2680366C (en) | 2007-03-09 | 2016-06-21 | University Health Network | Inhibitors of carnitine palmitoyltransferase and treating cancer |
| DE102007013856A1 (de) | 2007-03-20 | 2008-09-25 | Merck Patent Gmbh | Substituierte Tetrahydropyrrolochinoline |
| WO2008153027A1 (ja) * | 2007-06-11 | 2008-12-18 | Takeda Pharmaceutical Company Limited | ピロロキノリン誘導体およびその用途 |
| WO2009015485A1 (en) * | 2007-08-01 | 2009-02-05 | University Health Network | Cyclic inhibitors of carnitine palmitoyltransferase and treating cancer |
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| US5288725A (en) | 1992-10-15 | 1994-02-22 | Merck & Co., Inc. | Pyrroloquinoline Bradykinin antagonist |
| DE69518075T2 (de) * | 1994-05-24 | 2001-03-22 | F. Hoffmann-La Roche Ag, Basel | Tricyclische dicarbonylderivate |
| IT1283171B1 (it) | 1996-03-01 | 1998-04-16 | Interdipartimentale Di Ricerca | Composti solubili antagonisti delle tachichinine loro preparazione e loro uso in composizioni farmaceutiche |
| EP1334089A1 (en) * | 2000-11-13 | 2003-08-13 | GlaxoSmithKline S.p.A. | Quinoline derivatives as nk-3 and nk-2 antagonists |
| GB0027701D0 (en) | 2000-11-13 | 2000-12-27 | Smithkline Beecham Spa | Novel compounds |
| EP1385839B1 (en) | 2001-04-11 | 2006-02-22 | GlaxoSmithKline S.p.A. | 3-substituted quinoline-4-carboxamide derivatives as nk-3 and nk-2 receptor antagonists |
| JP2004134705A (ja) | 2002-10-15 | 2004-04-30 | Jiaotong Univ | 金属酸化膜半導体電界効果トランジスタおよびそのゲート構造 |
| RU2384571C2 (ru) * | 2004-04-28 | 2010-03-20 | Такеда Фармасьютикал Компани Лимитед | Конденсированное хинолиновое производное и его применение |
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- 2005-04-28 KR KR1020067024809A patent/KR20070015598A/ko not_active Ceased
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