CR8755A - Derivado de quinolina fusionada y uso del mismo - Google Patents
Derivado de quinolina fusionada y uso del mismoInfo
- Publication number
- CR8755A CR8755A CR8755A CR8755A CR8755A CR 8755 A CR8755 A CR 8755A CR 8755 A CR8755 A CR 8755A CR 8755 A CR8755 A CR 8755A CR 8755 A CR8755 A CR 8755A
- Authority
- CR
- Costa Rica
- Prior art keywords
- substituent
- optionally
- group optionally
- acyl
- hydrogen atom
- Prior art date
Links
- UABNNDYJUIQZQZ-UHFFFAOYSA-N 1-(4-chlorobenzoyl)-2-(3,4-dimethoxyphenyl)-2,3a-dihydro-1h-pyrrolo[1,2-a]quinoline-3,3-dicarbonitrile Chemical compound C1=C(OC)C(OC)=CC=C1C1C(C#N)(C#N)C(C=CC=2C3=CC=CC=2)N3C1C(=O)C1=CC=C(Cl)C=C1 UABNNDYJUIQZQZ-UHFFFAOYSA-N 0.000 title 1
- 125000001424 substituent group Chemical group 0.000 abstract 24
- 125000002252 acyl group Chemical group 0.000 abstract 5
- 125000001183 hydrocarbyl group Chemical group 0.000 abstract 5
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 5
- 125000002924 primary amino group Chemical group [H]N([H])* 0.000 abstract 5
- 125000000623 heterocyclic group Chemical group 0.000 abstract 4
- 150000003573 thiols Chemical class 0.000 abstract 4
- 125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 3
- 208000020401 Depressive disease Diseases 0.000 abstract 1
- 125000005090 alkenylcarbonyl group Chemical group 0.000 abstract 1
- 125000004448 alkyl carbonyl group Chemical group 0.000 abstract 1
- 125000004432 carbon atom Chemical group C* 0.000 abstract 1
- 239000003795 chemical substances by application Substances 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 125000004093 cyano group Chemical group *C#N 0.000 abstract 1
- 125000004122 cyclic group Chemical group 0.000 abstract 1
- 125000000753 cycloalkyl group Chemical group 0.000 abstract 1
- 229910052736 halogen Inorganic materials 0.000 abstract 1
- 150000002367 halogens Chemical class 0.000 abstract 1
- 208000024714 major depressive disease Diseases 0.000 abstract 1
- 201000003995 melancholia Diseases 0.000 abstract 1
- 125000000449 nitro group Chemical group [O-][N+](*)=O 0.000 abstract 1
- 238000011321 prophylaxis Methods 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 238000011282 treatment Methods 0.000 abstract 1
Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
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Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Veterinary Medicine (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Pulmonology (AREA)
- Immunology (AREA)
- Cardiology (AREA)
- Virology (AREA)
- Physical Education & Sports Medicine (AREA)
- Dermatology (AREA)
- Heart & Thoracic Surgery (AREA)
- Pain & Pain Management (AREA)
- Urology & Nephrology (AREA)
- Rheumatology (AREA)
- Communicable Diseases (AREA)
- Hospice & Palliative Care (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Oncology (AREA)
- Psychiatry (AREA)
- Otolaryngology (AREA)
- Molecular Biology (AREA)
- Psychology (AREA)
- Hematology (AREA)
- Toxicology (AREA)
- Biotechnology (AREA)
- Anesthesiology (AREA)
Abstract
Se dirige en la provision de un derivado de quinolina que tiene una accion antagonista del receptor de neuroquinina 2(NK2) y se refiere a un compuesto representado por la formula (I)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2004134705 | 2004-04-28 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CR8755A true CR8755A (es) | 2007-01-17 |
Family
ID=34966886
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CR8755A CR8755A (es) | 2004-04-28 | 2006-11-17 | Derivado de quinolina fusionada y uso del mismo |
Country Status (27)
| Country | Link |
|---|---|
| US (4) | US7592453B2 (es) |
| EP (2) | EP2080760A1 (es) |
| JP (2) | JP4361566B2 (es) |
| KR (1) | KR20070015598A (es) |
| CN (1) | CN1976932A (es) |
| AT (1) | ATE416176T1 (es) |
| AU (1) | AU2005238388B2 (es) |
| BR (1) | BRPI0510365A (es) |
| CA (1) | CA2565018A1 (es) |
| CR (1) | CR8755A (es) |
| CY (1) | CY1109222T1 (es) |
| DE (1) | DE602005011424D1 (es) |
| DK (1) | DK1740584T5 (es) |
| ES (1) | ES2318483T4 (es) |
| HR (1) | HRP20090121T5 (es) |
| MX (1) | MXPA06012323A (es) |
| MY (1) | MY143370A (es) |
| NO (1) | NO20065494L (es) |
| NZ (1) | NZ550983A (es) |
| PL (1) | PL1740584T3 (es) |
| PT (1) | PT1740584E (es) |
| RS (1) | RS50756B (es) |
| RU (1) | RU2384571C2 (es) |
| SI (1) | SI1740584T1 (es) |
| TW (1) | TW200540155A (es) |
| WO (1) | WO2005105802A1 (es) |
| ZA (1) | ZA200609261B (es) |
Families Citing this family (39)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ZA200609261B (en) * | 2004-04-28 | 2008-08-27 | Takeda Pharmaceutical | Fused quinoline derivative and use thereof |
| JP4836280B2 (ja) | 2004-06-18 | 2011-12-14 | ノバルティス バクシンズ アンド ダイアグノスティックス，インコーポレーテッド | 癌を治療するためのキネシンスピンドルタンパク質（ｋｓｐ）阻害剤としてのｎ−（１−（１−ベンジル−４−フェニル−１ｈ−イミダゾール−２−イル）−２，２−ジメチルプロピル）ベンズアミド誘導体および関連化合物 |
| AU2005295167B2 (en) | 2004-10-20 | 2012-05-10 | The Regents Of The University Of California | Improved inhibitors for the soluble epoxide hydrolase |
| DE102005027170A1 (de) * | 2005-06-13 | 2006-12-14 | Merck Patent Gmbh | Substituierte Tetrahydrochinoline |
| GB0522715D0 (en) | 2005-11-08 | 2005-12-14 | Helperby Therapeutics Ltd | New use |
| WO2007074491A1 (en) * | 2005-12-28 | 2007-07-05 | Universita Degli Studi Di Siena | HETEROTRICYCLIC AMIDE DERIVATIVES AS NEUROKININ-l (NKl) RECEPTOR LIGANDS |
| JP4509080B2 (ja) * | 2006-09-28 | 2010-07-21 | 信越化学工業株式会社 | シルセスキオキサン系化合物混合物及び加水分解性シラン化合物、その製造方法及びそれを用いたレジスト組成物並びにパターン形成方法及び基板の加工方法 |
| EP2099444A4 (en) | 2006-12-14 | 2012-11-07 | Nps Pharma Inc | USE OF D-SERIN DERIVATIVES FOR THE TREATMENT OF ANTIBODIES |
| US8410150B2 (en) | 2007-03-09 | 2013-04-02 | University Health Network | Inhibitors of carnitine palmitoyltransferase and treating cancer |
| DE102007013856A1 (de) | 2007-03-20 | 2008-09-25 | Merck Patent Gmbh | Substituierte Tetrahydropyrrolochinoline |
| WO2008153027A1 (ja) * | 2007-06-11 | 2008-12-18 | Takeda Pharmaceutical Company Limited | ピロロキノリン誘導体およびその用途 |
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|---|---|---|---|---|
| US5288725A (en) | 1992-10-15 | 1994-02-22 | Merck & Co., Inc. | Pyrroloquinoline Bradykinin antagonist |
| DE69518075T2 (de) * | 1994-05-24 | 2001-03-22 | F. Hoffmann-La Roche Ag, Basel | Tricyclische dicarbonylderivate |
| IT1283171B1 (it) | 1996-03-01 | 1998-04-16 | Interdipartimentale Di Ricerca | Composti solubili antagonisti delle tachichinine loro preparazione e loro uso in composizioni farmaceutiche |
| JP2004517062A (ja) | 2000-11-13 | 2004-06-10 | グラクソスミスクライン・ソシエタ・ペル・アチオニ | Ｎｋ−３およびｎｋ−２アンタゴニストとしてのキノリン誘導体 |
| GB0027701D0 (en) | 2000-11-13 | 2000-12-27 | Smithkline Beecham Spa | Novel compounds |
| ATE313539T1 (de) | 2001-04-11 | 2006-01-15 | Glaxosmithkline Spa | Chinolin-4-carboxamidderivate als nk-3 und nk-2 rezeptor antagonisten |
| JP2004134705A (ja) | 2002-10-15 | 2004-04-30 | Jiaotong Univ | 金属酸化膜半導体電界効果トランジスタおよびそのゲート構造 |
| ZA200609261B (en) * | 2004-04-28 | 2008-08-27 | Takeda Pharmaceutical | Fused quinoline derivative and use thereof |
-
2005
- 2005-04-28 ZA ZA200609261A patent/ZA200609261B/xx unknown
- 2005-04-28 EP EP08020921A patent/EP2080760A1/en not_active Withdrawn
- 2005-04-28 AT AT05738868T patent/ATE416176T1/de active
- 2005-04-28 PL PL05738868T patent/PL1740584T3/pl unknown
- 2005-04-28 RS RSP-2009/0085A patent/RS50756B/sr unknown
- 2005-04-28 HR HR20090121T patent/HRP20090121T5/hr unknown
- 2005-04-28 JP JP2006540061A patent/JP4361566B2/ja not_active Expired - Fee Related
- 2005-04-28 TW TW094113637A patent/TW200540155A/zh unknown
- 2005-04-28 AU AU2005238388A patent/AU2005238388B2/en not_active Expired - Fee Related
- 2005-04-28 BR BRPI0510365-7A patent/BRPI0510365A/pt not_active IP Right Cessation
- 2005-04-28 WO PCT/JP2005/008558 patent/WO2005105802A1/en not_active Ceased
- 2005-04-28 SI SI200530595T patent/SI1740584T1/sl unknown
- 2005-04-28 PT PT05738868T patent/PT1740584E/pt unknown
- 2005-04-28 CA CA002565018A patent/CA2565018A1/en not_active Abandoned
- 2005-04-28 DK DK05738868.8T patent/DK1740584T5/da active
- 2005-04-28 KR KR1020067024809A patent/KR20070015598A/ko not_active Ceased
- 2005-04-28 EP EP05738868A patent/EP1740584B9/en not_active Expired - Lifetime
- 2005-04-28 MY MYPI20051875A patent/MY143370A/en unknown
- 2005-04-28 NZ NZ550983A patent/NZ550983A/en unknown
- 2005-04-28 US US11/587,788 patent/US7592453B2/en not_active Expired - Fee Related
- 2005-04-28 RU RU2006141842/04A patent/RU2384571C2/ru not_active IP Right Cessation
- 2005-04-28 DE DE602005011424T patent/DE602005011424D1/de not_active Expired - Lifetime
- 2005-04-28 MX MXPA06012323A patent/MXPA06012323A/es active IP Right Grant
- 2005-04-28 CN CNA200580021496XA patent/CN1976932A/zh active Pending
- 2005-04-28 ES ES05738868T patent/ES2318483T4/es not_active Expired - Lifetime
-
2006
- 2006-11-17 CR CR8755A patent/CR8755A/es not_active Application Discontinuation
- 2006-11-28 NO NO20065494A patent/NO20065494L/no not_active Application Discontinuation
-
2009
- 2009-02-27 CY CY20091100236T patent/CY1109222T1/el unknown
- 2009-06-02 US US12/476,619 patent/US7973163B2/en not_active Expired - Fee Related
- 2009-06-02 US US12/476,626 patent/US7943770B2/en not_active Expired - Fee Related
- 2009-06-23 JP JP2009149204A patent/JP2009256362A/ja not_active Abandoned
- 2009-07-07 US US12/498,629 patent/US20090275568A1/en not_active Abandoned
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