CR9111A - Metabolitos glucoronidos y epimeros de los mismos de tigeciclina - Google Patents

Metabolitos glucoronidos y epimeros de los mismos de tigeciclina

Info

Publication number
CR9111A
CR9111A CR9111A CR9111A CR9111A CR 9111 A CR9111 A CR 9111A CR 9111 A CR9111 A CR 9111A CR 9111 A CR9111 A CR 9111A CR 9111 A CR9111 A CR 9111A
Authority
CR
Costa Rica
Prior art keywords
tigecicline
glucoronid
epimeral
metabolites
same
Prior art date
Application number
CR9111A
Other languages
English (en)
Inventor
A Jordon Ronald
Demaio William
Hoffman Matthew
Original Assignee
Wyeth Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Wyeth Corp filed Critical Wyeth Corp
Publication of CR9111A publication Critical patent/CR9111A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J17/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, having an oxygen-containing hetero ring not condensed with the cyclopenta(a)hydrophenanthrene skeleton
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Rheumatology (AREA)
  • Endocrinology (AREA)
  • Communicable Diseases (AREA)
  • Immunology (AREA)
  • Dermatology (AREA)
  • Reproductive Health (AREA)
  • Pulmonology (AREA)
  • Oncology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Peptides Or Proteins (AREA)
  • Saccharide Compounds (AREA)
  • Steroid Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Investigating Or Analysing Materials By Optical Means (AREA)
  • Other Investigation Or Analysis Of Materials By Electrical Means (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)

Abstract

Un metabolismo glucuronico de tigeciclina y su correspondiente epimero, fueron identificados en humanos tratados con tigeciclina. Datos espectrales de masa se utilizaron en l aidentificacion de estas estructuras.
CR9111A 2004-11-05 2007-05-09 Metabolitos glucoronidos y epimeros de los mismos de tigeciclina CR9111A (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US62512104P 2004-11-05 2004-11-05

Publications (1)

Publication Number Publication Date
CR9111A true CR9111A (es) 2008-01-21

Family

ID=36337018

Family Applications (1)

Application Number Title Priority Date Filing Date
CR9111A CR9111A (es) 2004-11-05 2007-05-09 Metabolitos glucoronidos y epimeros de los mismos de tigeciclina

Country Status (22)

Country Link
US (1) US7534766B2 (es)
EP (1) EP1807441A2 (es)
JP (1) JP2008519038A (es)
KR (1) KR20070085761A (es)
CN (1) CN101132799A (es)
AR (1) AR051236A1 (es)
AU (1) AU2005304957A1 (es)
BR (1) BRPI0517715A (es)
CA (1) CA2586245A1 (es)
CR (1) CR9111A (es)
GT (1) GT200500320A (es)
HN (1) HN2005030775A (es)
IL (1) IL182640A0 (es)
MX (1) MX2007005105A (es)
NO (1) NO20072226L (es)
PA (1) PA8652001A1 (es)
PE (1) PE20061048A1 (es)
RU (1) RU2007116800A (es)
SV (1) SV2006002294A (es)
TW (1) TW200628485A (es)
WO (1) WO2006052717A2 (es)
ZA (1) ZA200703624B (es)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MX2010001255A (es) * 2007-07-31 2010-12-06 Gilead Colorado Inc Metabolitos y derivados de ambrisentan.
US8766177B2 (en) 2010-10-11 2014-07-01 University Of North Texas Nanomanipulation coupled nanospray mass spectrometry (NMS)
JP6134191B2 (ja) 2013-04-07 2017-05-24 村川 惠美 回転型セミバッチａｌｄ装置

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5494903A (en) * 1991-10-04 1996-02-27 American Cyanamid Company 7-substituted-9-substituted amino-6-demethyl-6-deoxytetracyclines
ES2168254T3 (es) 1991-10-04 2002-06-16 American Cyanamid Co Nuevas 7-sustituidas-9-(amino sustituido)-6-desmetil-6-desoxitetraciclinas.
SG47520A1 (en) 1992-08-13 1998-04-17 American Cyanamid Co New method for the production of 9-amino-6-demethyl-6-deoxytetracycline
US5420272A (en) 1992-08-13 1995-05-30 American Cyanamid Company 7-(substituted)-8-(substituted)-9-](substituted glycyl)amido]-6-demethyl-6-deoxytetracyclines
US5284963A (en) 1992-08-13 1994-02-08 American Cyanamid Company Method of producing 7-(substituted)-9-[(substituted glycyl)-amidol]-6-demethyl-6-deoxytetra-cyclines
US5328902A (en) 1992-08-13 1994-07-12 American Cyanamid Co. 7-(substituted)-9-[(substituted glycyl)amido]-6-demethyl-6-deoxytetracyclines
WO2005009943A2 (en) 2003-07-09 2005-02-03 Paratek Pharmaceuticals, Inc. Substituted tetracycline compounds
EP1656341A1 (en) 2003-07-09 2006-05-17 Paratek Pharmaceuticals, Inc. Prodrugs of 9-aminomethyl tetracycline compounds
US20050148553A1 (en) * 2003-09-05 2005-07-07 Testa Raymond T. Use of tigecycline, alone, or in combination with rifampin to treat osteomyelitis and/or septic arthritis

Also Published As

Publication number Publication date
MX2007005105A (es) 2007-06-26
CN101132799A (zh) 2008-02-27
ZA200703624B (en) 2009-10-28
PE20061048A1 (es) 2006-11-15
NO20072226L (no) 2007-06-04
CA2586245A1 (en) 2006-05-18
AR051236A1 (es) 2006-12-27
SV2006002294A (es) 2006-10-13
GT200500320A (es) 2006-06-02
PA8652001A1 (es) 2006-10-13
TW200628485A (en) 2006-08-16
US7534766B2 (en) 2009-05-19
BRPI0517715A (pt) 2008-10-21
KR20070085761A (ko) 2007-08-27
JP2008519038A (ja) 2008-06-05
AU2005304957A1 (en) 2006-05-18
WO2006052717A2 (en) 2006-05-18
IL182640A0 (en) 2007-07-24
EP1807441A2 (en) 2007-07-18
HN2005030775A (es) 2006-12-18
RU2007116800A (ru) 2008-12-10
WO2006052717A3 (en) 2007-11-15
US20060128950A1 (en) 2006-06-15

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Legal Events

Date Code Title Description
FA Abandonment or withdrawal (granting procedure)