NO20072226L - Glukuronidmetabolitter og deres epimerer av tigecyklin - Google Patents

Glukuronidmetabolitter og deres epimerer av tigecyklin

Info

Publication number
NO20072226L
NO20072226L NO20072226A NO20072226A NO20072226L NO 20072226 L NO20072226 L NO 20072226L NO 20072226 A NO20072226 A NO 20072226A NO 20072226 A NO20072226 A NO 20072226A NO 20072226 L NO20072226 L NO 20072226L
Authority
NO
Norway
Prior art keywords
tigecycline
epimers
glucuronide metabolites
glucuronide
metabolites
Prior art date
Application number
NO20072226A
Other languages
English (en)
Inventor
William Demaio
Ronald A Jordon
Matthew Hoffman
Original Assignee
Wyeth Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Wyeth Corp filed Critical Wyeth Corp
Publication of NO20072226L publication Critical patent/NO20072226L/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J17/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, having an oxygen-containing hetero ring not condensed with the cyclopenta(a)hydrophenanthrene skeleton
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Rheumatology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Communicable Diseases (AREA)
  • Immunology (AREA)
  • Dermatology (AREA)
  • Endocrinology (AREA)
  • Reproductive Health (AREA)
  • Pulmonology (AREA)
  • Oncology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Saccharide Compounds (AREA)
  • Peptides Or Proteins (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Steroid Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Investigating Or Analysing Materials By Optical Means (AREA)
  • Other Investigation Or Analysis Of Materials By Electrical Means (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)

Abstract

En glukuronidmetabolitt av tigecyklin og dens korresponderende epimer har blitt idintifisert i mennesker som er behandlet med tigecyklin. Massespektrale data har blitt benyttet for å identifisere disse strukturene.
NO20072226A 2004-11-05 2007-04-30 Glukuronidmetabolitter og deres epimerer av tigecyklin NO20072226L (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US62512104P 2004-11-05 2004-11-05
PCT/US2005/039944 WO2006052717A2 (en) 2004-11-05 2005-11-03 Glucuronide metabolites and epimers thereof of tigecycline

Publications (1)

Publication Number Publication Date
NO20072226L true NO20072226L (no) 2007-06-04

Family

ID=36337018

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20072226A NO20072226L (no) 2004-11-05 2007-04-30 Glukuronidmetabolitter og deres epimerer av tigecyklin

Country Status (22)

Country Link
US (1) US7534766B2 (no)
EP (1) EP1807441A2 (no)
JP (1) JP2008519038A (no)
KR (1) KR20070085761A (no)
CN (1) CN101132799A (no)
AR (1) AR051236A1 (no)
AU (1) AU2005304957A1 (no)
BR (1) BRPI0517715A (no)
CA (1) CA2586245A1 (no)
CR (1) CR9111A (no)
GT (1) GT200500320A (no)
HN (1) HN2005030775A (no)
IL (1) IL182640A0 (no)
MX (1) MX2007005105A (no)
NO (1) NO20072226L (no)
PA (1) PA8652001A1 (no)
PE (1) PE20061048A1 (no)
RU (1) RU2007116800A (no)
SV (1) SV2006002294A (no)
TW (1) TW200628485A (no)
WO (1) WO2006052717A2 (no)
ZA (1) ZA200703624B (no)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2008282773B8 (en) * 2007-07-31 2013-03-07 Gilead Sciences, Inc. Metabolites and derivatives of ambrisentan
US8766177B2 (en) 2010-10-11 2014-07-01 University Of North Texas Nanomanipulation coupled nanospray mass spectrometry (NMS)
JP6134191B2 (ja) 2013-04-07 2017-05-24 村川 惠美 回転型セミバッチａｌｄ装置

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5494903A (en) 1991-10-04 1996-02-27 American Cyanamid Company 7-substituted-9-substituted amino-6-demethyl-6-deoxytetracyclines
SG52361A1 (en) 1991-10-04 1998-09-28 American Cyanamid Co Novel 7-substituted-9-substituted amino-6-demethyl-6-deoxytetracyclines
US5284963A (en) 1992-08-13 1994-02-08 American Cyanamid Company Method of producing 7-(substituted)-9-[(substituted glycyl)-amidol]-6-demethyl-6-deoxytetra-cyclines
SG47520A1 (en) 1992-08-13 1998-04-17 American Cyanamid Co New method for the production of 9-amino-6-demethyl-6-deoxytetracycline
US5420272A (en) 1992-08-13 1995-05-30 American Cyanamid Company 7-(substituted)-8-(substituted)-9-](substituted glycyl)amido]-6-demethyl-6-deoxytetracyclines
US5328902A (en) 1992-08-13 1994-07-12 American Cyanamid Co. 7-(substituted)-9-[(substituted glycyl)amido]-6-demethyl-6-deoxytetracyclines
US20050143352A1 (en) 2003-07-09 2005-06-30 Paratek Pharmaceuticals, Inc. Substituted tetracycline compounds
AU2004259661B2 (en) 2003-07-09 2011-11-10 Paratek Pharmaceuticals, Inc. Prodrugs of 9-aminomethyl tetracycline compounds
US20050148553A1 (en) 2003-09-05 2005-07-07 Testa Raymond T. Use of tigecycline, alone, or in combination with rifampin to treat osteomyelitis and/or septic arthritis

Also Published As

Publication number Publication date
TW200628485A (en) 2006-08-16
US7534766B2 (en) 2009-05-19
KR20070085761A (ko) 2007-08-27
CN101132799A (zh) 2008-02-27
IL182640A0 (en) 2007-07-24
CR9111A (es) 2008-01-21
PA8652001A1 (es) 2006-10-13
ZA200703624B (en) 2009-10-28
EP1807441A2 (en) 2007-07-18
HN2005030775A (es) 2006-12-18
PE20061048A1 (es) 2006-11-15
WO2006052717A2 (en) 2006-05-18
CA2586245A1 (en) 2006-05-18
GT200500320A (es) 2006-06-02
US20060128950A1 (en) 2006-06-15
SV2006002294A (es) 2006-10-13
RU2007116800A (ru) 2008-12-10
AU2005304957A1 (en) 2006-05-18
MX2007005105A (es) 2007-06-26
WO2006052717A3 (en) 2007-11-15
JP2008519038A (ja) 2008-06-05
BRPI0517715A (pt) 2008-10-21
AR051236A1 (es) 2006-12-27

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Legal Events

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FC2A Withdrawal, rejection or dismissal of laid open patent application