CR9315A - Metodos y sistemas para el diagnostico, pronostico y seleccion del tratamiento de la leucemia - Google Patents

Metodos y sistemas para el diagnostico, pronostico y seleccion del tratamiento de la leucemia

Info

Publication number
CR9315A
CR9315A CR9315A CR9315A CR9315A CR 9315 A CR9315 A CR 9315A CR 9315 A CR9315 A CR 9315A CR 9315 A CR9315 A CR 9315A CR 9315 A CR9315 A CR 9315A
Authority
CR
Costa Rica
Prior art keywords
leukemia
diagnosis
selection
systems
treatment
Prior art date
Application number
CR9315A
Other languages
English (en)
Inventor
Michael E Burczynski
Frederick Immermann
Natalie C Twine
Jennifer Ann Stover
Andrew J Dorner
Original Assignee
Wyeth Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Wyeth Corp filed Critical Wyeth Corp
Publication of CR9315A publication Critical patent/CR9315A/es

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/575—Immunoassay; Biospecific binding assay; Materials therefor for cancer
    • G01N33/57505—Immunoassay; Biospecific binding assay; Materials therefor for cancer of the blood, e.g. leukaemia
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813—Hybridisation assays
    • C12Q1/6834—Enzymatic or biochemical coupling of nucleic acids to a solid phase
    • C12Q1/6837—Enzymatic or biochemical coupling of nucleic acids to a solid phase using probe arrays or probe chips
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • C12Q1/6886—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00—Detection or diagnosis of diseases
    • G01N2800/52—Predicting or monitoring the response to treatment, e.g. for selection of therapy based on assay results in personalised medicine; Prognosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Organic Chemistry (AREA)
  • Hematology (AREA)
  • Analytical Chemistry (AREA)
  • Urology & Nephrology (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Physics & Mathematics (AREA)
  • Microbiology (AREA)
  • Pathology (AREA)
  • General Health & Medical Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Medicinal Chemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Food Science & Technology (AREA)
  • Cell Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Hospice & Palliative Care (AREA)
  • Oncology (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)

Abstract

La presente invencion suministra metodos, sistemas y equipos para el pronostico, el diagnostico y la seleccion de tratamiento del AML u otros tipos de leucemia. Los genes de pronostico de resultados clinicos de pacientes con leucemia se pueden identificar de acuerdo con la presente invencion. Los genes de la enfermedad de leucemia tambien se pueden identificar de acuerdo con la presente invencion.
CR9315A 2005-02-16 2007-08-15 Metodos y sistemas para el diagnostico, pronostico y seleccion del tratamiento de la leucemia CR9315A (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US65311705P 2005-02-16 2005-02-16

Publications (1)

Publication Number Publication Date
CR9315A true CR9315A (es) 2008-01-21

Family

ID=36659874

Family Applications (1)

Application Number Title Priority Date Filing Date
CR9315A CR9315A (es) 2005-02-16 2007-08-15 Metodos y sistemas para el diagnostico, pronostico y seleccion del tratamiento de la leucemia

Country Status (14)

Country Link
US (1) US20080280774A1 (es)
EP (1) EP1848994A2 (es)
JP (1) JP2008529557A (es)
KR (1) KR20070106027A (es)
CN (1) CN101156067A (es)
AU (1) AU2006214034A1 (es)
BR (1) BRPI0607753A2 (es)
CA (1) CA2598025A1 (es)
CR (1) CR9315A (es)
IL (1) IL185189A0 (es)
MX (1) MX2007009911A (es)
NO (1) NO20074104L (es)
RU (1) RU2007130722A (es)
WO (1) WO2006089233A2 (es)

Families Citing this family (65)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2008545399A (ja) * 2005-05-18 2008-12-18 ワイス 白血病疾患遺伝子およびその使用
US10460080B2 (en) 2005-09-08 2019-10-29 Gearbox, Llc Accessing predictive data
KR100617467B1 (ko) * 2005-09-27 2006-09-01 디지탈 지노믹스(주) 급성 골수성 백혈병 환자의 항암제 치료 반응성 예측용마커
US20090075266A1 (en) * 2007-09-14 2009-03-19 Predictive Biosciences Corporation Multiple analyte diagnostic readout
CN101932938B (zh) 2007-11-30 2014-08-27 克雷特诊疗服务公司 作为标记物用于化学疗法的tle3
CN102046660A (zh) 2008-03-26 2011-05-04 塞勒兰特治疗公司 骨髓性血液学增殖性病症相关的免疫球蛋白和/或toll样受体蛋白及其用途
EP2113257A1 (en) 2008-04-30 2009-11-04 Consorzio per il Centro di Biomedica Moleculare Scrl Polyelectrolyte with positive net charge for use as medicament and diagnostic for cancer
US20100041055A1 (en) * 2008-08-12 2010-02-18 Stokes Bio Limited Novel gene normalization methods
US9528160B2 (en) 2008-11-07 2016-12-27 Adaptive Biotechnolgies Corp. Rare clonotypes and uses thereof
US8691510B2 (en) * 2008-11-07 2014-04-08 Sequenta, Inc. Sequence analysis of complex amplicons
US9506119B2 (en) 2008-11-07 2016-11-29 Adaptive Biotechnologies Corp. Method of sequence determination using sequence tags
EP2364368B1 (en) 2008-11-07 2014-01-15 Sequenta, Inc. Methods of monitoring conditions by sequence analysis
US8628927B2 (en) 2008-11-07 2014-01-14 Sequenta, Inc. Monitoring health and disease status using clonotype profiles
US9365901B2 (en) 2008-11-07 2016-06-14 Adaptive Biotechnologies Corp. Monitoring immunoglobulin heavy chain evolution in B-cell acute lymphoblastic leukemia
US8748103B2 (en) 2008-11-07 2014-06-10 Sequenta, Inc. Monitoring health and disease status using clonotype profiles
DK3059337T3 (da) 2009-01-15 2019-07-22 Adaptive Biotechnologies Corp Adaptive immunity profiling og metoder til frembringelse af monoklonale antibodier
KR100937720B1 (ko) * 2009-04-20 2010-01-20 전남대학교산학협력단 ＣＦＨ 또는 ＡｐｏＨ를 급성골수성백혈병 관해 진단용 생화학적 마커로 사용하는 방법
RU2014144463A (ru) 2009-06-25 2015-06-20 Фред Хатчинсон Кансэр Рисёч Сентер Способ измерения адаптивного иммунитета
EP2452207B1 (en) * 2009-07-07 2015-08-12 Koninklijke Philips N.V. Dynamic pet imaging with isotope contamination compensation
GB2472856B (en) 2009-08-21 2012-07-11 Cantargia Ab IL1-RAP modulators and uses thereof
JP5503942B2 (ja) 2009-10-30 2014-05-28 シスメックス株式会社 疾患の罹患の判定方法
US9043160B1 (en) 2009-11-09 2015-05-26 Sequenta, Inc. Method of determining clonotypes and clonotype profiles
JP5467267B2 (ja) * 2010-03-05 2014-04-09 国立大学法人大阪大学 機器制御装置、機器システム、機器制御方法、機器制御プログラム、および記録媒体
WO2012098407A1 (en) 2011-01-19 2012-07-26 Cantargia Ab Anti - il1rap antibodies and their use for treating human
US9012422B2 (en) * 2011-08-10 2015-04-21 Wake Forest University Health Sciences Method of treating acute myelogenous leukemia
WO2013023015A2 (en) 2011-08-11 2013-02-14 Albert Einstein College Of Medicine Of Yeshiva University Targets for diagnosis, prognosis and therapy of acute myeloid leukemia and myelodysplastic syndromes
US10385475B2 (en) 2011-09-12 2019-08-20 Adaptive Biotechnologies Corp. Random array sequencing of low-complexity libraries
US9279159B2 (en) 2011-10-21 2016-03-08 Adaptive Biotechnologies Corporation Quantification of adaptive immune cell genomes in a complex mixture of cells
EP3388535B1 (en) 2011-12-09 2021-03-24 Adaptive Biotechnologies Corporation Diagnosis of lymphoid malignancies and minimal residual disease detection
US9499865B2 (en) 2011-12-13 2016-11-22 Adaptive Biotechnologies Corp. Detection and measurement of tissue-infiltrating lymphocytes
JP6156621B2 (ja) * 2012-02-14 2017-07-05 国立大学法人 岡山大学 Ａｔｌｌの診断のためのデータ取得方法、ａｔｌｌ診断用キットおよびａｔｌｌ診断システム
DK2823060T3 (en) 2012-03-05 2018-05-28 Adaptive Biotechnologies Corp Determination of associated immune receptor chains from frequency-matched subunits
EP3091089B1 (en) 2012-05-08 2019-01-23 Adaptive Biotechnologies Corporation Method for measuring and calibrating amplification bias in multiplexed pcr reactions
IN2014DN10075A (es) * 2012-05-31 2015-08-21 Univ Kinki
US20160002731A1 (en) 2012-10-01 2016-01-07 Adaptive Biotechnologies Corporation Immunocompetence assessment by adaptive immune receptor diversity and clonality characterization
US10150996B2 (en) 2012-10-19 2018-12-11 Adaptive Biotechnologies Corp. Quantification of adaptive immune cell genomes in a complex mixture of cells
US9708657B2 (en) 2013-07-01 2017-07-18 Adaptive Biotechnologies Corp. Method for generating clonotype profiles using sequence tags
WO2015134787A2 (en) 2014-03-05 2015-09-11 Adaptive Biotechnologies Corporation Methods using randomer-containing synthetic molecules
US10066265B2 (en) 2014-04-01 2018-09-04 Adaptive Biotechnologies Corp. Determining antigen-specific t-cells
CA2966201A1 (en) 2014-10-29 2016-05-06 Adaptive Biotechnologies Corp. Highly-multiplexed simultaneous detection of nucleic acids encoding paired adaptive immune receptor heterodimers from many samples
US10246701B2 (en) 2014-11-14 2019-04-02 Adaptive Biotechnologies Corp. Multiplexed digital quantitation of rearranged lymphoid receptors in a complex mixture
EP3224384A4 (en) 2014-11-25 2018-04-18 Adaptive Biotechnologies Corp. Characterization of adaptive immune response to vaccination or infection using immune repertoire sequencing
US11047008B2 (en) 2015-02-24 2021-06-29 Adaptive Biotechnologies Corporation Methods for diagnosing infectious disease and determining HLA status using immune repertoire sequencing
WO2016161273A1 (en) 2015-04-01 2016-10-06 Adaptive Biotechnologies Corp. Method of identifying human compatible t cell receptors specific for an antigenic target
US11474106B2 (en) 2015-07-08 2022-10-18 Lawrence Livermore National Security, Llc Methods for cytotoxic chemotherapy-based predictive assays
WO2017180489A1 (en) 2016-04-12 2017-10-19 The Johns Hopkins University Quantitative determination of nucleoside analogue drugs in genomic dna or rna
US10428325B1 (en) 2016-09-21 2019-10-01 Adaptive Biotechnologies Corporation Identification of antigen-specific B cell receptors
WO2018132766A1 (en) * 2017-01-12 2018-07-19 The Regents Of The University Of California Cytotoxic chemotherapy-based predictive assays for acute myeloid leukemia
CN106841624B (zh) * 2017-01-26 2019-02-22 庄磊靓 抗人cd4和抗人cd184单克隆抗体作为标志物的应用
US11254980B1 (en) 2017-11-29 2022-02-22 Adaptive Biotechnologies Corporation Methods of profiling targeted polynucleotides while mitigating sequencing depth requirements
CN108182347B (zh) * 2018-01-17 2022-02-22 广东工业大学 一种大规模跨平台基因表达数据分类方法
KR102327062B1 (ko) 2018-03-20 2021-11-17 딜로이트컨설팅유한회사 임상시험 결과 예측 장치 및 방법
CN109187987B (zh) * 2018-08-23 2021-05-11 中国人民解放军第三0九医院 Ms4a3蛋白作为标志物在诊断活动性结核病中的应用
WO2020067389A1 (ja) 2018-09-28 2020-04-02 旭化成ファーマ株式会社 抗悪性腫瘍剤による末梢神経障害の症状軽減及び／又は発症抑制のための医薬
CN109897900B (zh) * 2019-03-13 2023-04-07 温州医科大学 Epb42基因在肝癌sbrt疗效评估中的应用
CN112831560B (zh) * 2019-11-23 2022-07-22 山东大学齐鲁医院 γ-分泌酶激活蛋白基因和/或其编码的蛋白的新应用
CN112852964B (zh) * 2021-03-08 2022-02-11 镇江市第一人民医院 一种环状RNA hsa_circ_0059707及其特异性扩增引物和应用
CN116200482B (zh) * 2021-11-30 2025-11-14 中山大学孙逸仙纪念医院 肌萎缩侧索硬化症分子诊断标志物及其应用
CN114712381B (zh) * 2022-03-30 2024-04-26 浙江大学 Ak2基因在制备白血病诱导分化治疗药物中的应用
CN115029383B (zh) * 2022-04-21 2024-02-20 苏天生命科技(苏州)有限公司 Ms4a3蛋白在调控红细胞成熟中的应用
CN115896280A (zh) * 2022-05-10 2023-04-04 广西医科大学第一附属医院 一种人肝癌酪氨酸激酶抑制剂耐药标志物及其应用
CN115165838B (zh) * 2022-06-23 2025-09-30 中国医学科学院血液病医院(中国医学科学院血液学研究所) 基于拉曼光谱和血清代谢构建mds和aml鉴别模型的方法和试剂盒
EP4665387A2 (en) * 2023-02-17 2025-12-24 Calviri, Inc. Tryptophan neoantigen peptides for diagnostics, therapeutics, and vaccines
CN117737251B (zh) * 2024-02-21 2024-05-28 北京医院 一种aml诊断和预后的组合分子标志物
CN118465265A (zh) * 2024-04-08 2024-08-09 北京大学人民医院 与急性髓系白血病造血干细胞移植术后临床结局相关的生物标志物及其应用

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7625697B2 (en) * 1994-06-17 2009-12-01 The Board Of Trustees Of The Leland Stanford Junior University Methods for constructing subarrays and subarrays made thereby
US6647341B1 (en) * 1999-04-09 2003-11-11 Whitehead Institute For Biomedical Research Methods for classifying samples and ascertaining previously unknown classes
US20010044103A1 (en) * 1999-12-03 2001-11-22 Steeg Evan W. Methods for the diagnosis and prognosis of acute leukemias
US20040018513A1 (en) * 2002-03-22 2004-01-29 Downing James R Classification and prognosis prediction of acute lymphoblastic leukemia by gene expression profiling
WO2003102235A2 (en) * 2002-05-31 2003-12-11 Cancer Research Technology Limited Specific genetic markets for cytogenetically defined acute myeloid leukaemia
US20040152632A1 (en) * 2002-11-06 2004-08-05 Wyeth Combination therapy for the treatment of acute leukemia and myelodysplastic syndrome
CA2558366A1 (en) * 2004-02-23 2005-09-01 Erasmus Universiteit Rotterdam Classification, diagnosis and prognosis of acute myeloid leukemia by gene expression profiling
AR048945A1 (es) * 2004-05-06 2006-06-14 Veridex Llc Pronostico para leucemia mieloide cronica

Also Published As

Publication number Publication date
MX2007009911A (es) 2008-02-20
RU2007130722A (ru) 2009-03-27
US20080280774A1 (en) 2008-11-13
KR20070106027A (ko) 2007-10-31
AU2006214034A1 (en) 2006-08-24
BRPI0607753A2 (pt) 2009-10-06
WO2006089233A2 (en) 2006-08-24
WO2006089233A3 (en) 2007-03-29
CA2598025A1 (en) 2006-08-24
IL185189A0 (en) 2007-12-03
CN101156067A (zh) 2008-04-02
EP1848994A2 (en) 2007-10-31
NO20074104L (no) 2007-11-13
JP2008529557A (ja) 2008-08-07

Similar Documents

Publication Publication Date Title
Ghorbani et al. Application of various optical and electrochemical aptasensors for detection of human prostate specific antigen: A review
MX2007004176A (es) B7-h1 y metodos de diagnosis, prognosis, y tratamiento de cancer.
MX2009012722A (es) Variantes geneticas sobre chr 5p12 y 10q26 como marcadores para el uso en la evaluacion del riesgo, diagnostico, pronostico y tratamiento del cancer de mama.
ECSP11011541A (es) Antagonistas de la trayectoria hedgehog de ftalazina disustituida
MX2009010439A (es) Variantes geneticas de chr2 y chr16 como marcadores para el uso en valoracion, diagnosis, prognosis y tratamiento de riesgo de cancer de mama.
DOP2010000302A (es) Antagonistas de la trayectoria hedgehog de ftalazina disustituida
WO2006089233A3 (en) Methods and systems for diagnosis, prognosis and selection of treatment of leukemia
BR112012008019A2 (pt) derivados de purina úteis como inibidores de hsp90
CR20120213A (es) Métodos para el tratamiento del cáncer usando antagonistas de notch
ES2422739T3 (es) Composición para el diagnóstico, prevención o tratamiento de enfermedades relacionadas con células que expresan IL-8 o GRO-, que comprende MSC de UCB
AR077026A1 (es) Marcadores de riesgo para enfermedades cardiovasculares
CO6511283A2 (es) Primidinas sustituidas útiles en el tratamiento de enfermedades tales como cancer
ECSP088221A (es) Agonistas adrenoreceptores alfa2c
MX2019003148A (es) Base de datos, de datos moleculares, omicos, de inmunoterapia, metabolicos, epigeneticos y clinicos, integrados.
UY31105A1 (es) Predicción pronóstica del melanoma
MX2010014228A (es) Metodos y productos de diagnostico del p/gf-1 acompañante.
DE602006018709D1 (de) Estergebundene geminitensidverbindungen zur verwendung in der gentherapie
MX392267B (es) Metodos para evaluar el riesgo de desarrollar cancer de mama.
CR20110202A (es) Antagonistas de la via hedgehog de ftalazina disustituida
CR9100A (es) Metodos y sistemas para el pronostico y tratamiento de tumores solidos
EA200971068A1 (ru) Триазолиламинопиримидиновые соединения
ECSP11010816A (es) Nuevos Compuestos
MX378733B (es) Métodos in vitro y composiciones para identificar y usarse en el tratamiento de lupus.
UY32943A (es) Cultivar de arroz denominado "cl111"
CY1108399T1 (el) Τετραϋδροπυριδοθειοφαινια

Legal Events

Date Code Title Description
FA Abandonment or withdrawal (granting procedure)