CR9424A - Ibuprofeno solubilizado - Google Patents

Ibuprofeno solubilizado

Info

Publication number
CR9424A
CR9424A CR9424A CR9424A CR9424A CR 9424 A CR9424 A CR 9424A CR 9424 A CR9424 A CR 9424A CR 9424 A CR9424 A CR 9424A CR 9424 A CR9424 A CR 9424A
Authority
CR
Costa Rica
Prior art keywords
ibuprofen
sodium
potassium
glycinate
carbonate
Prior art date
Application number
CR9424A
Other languages
English (en)
Inventor
Peter Gruber
Original Assignee
Losan Pharma Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=35570762&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=CR9424(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Losan Pharma Gmbh filed Critical Losan Pharma Gmbh
Publication of CR9424A publication Critical patent/CR9424A/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1611—Inorganic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/192—Carboxylic acids, e.g. valproic acid having aromatic groups, e.g. sulindac, 2-aryl-propionic acids, ethacrynic acid 
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1682—Processes
    • A61K9/1688—Processes resulting in pure drug agglomerate optionally containing up to 5% of excipient
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2095—Tabletting processes

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Inorganic Chemistry (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)

Abstract

Un proceso para producir un ibuprofeno solubilizado, con preferencia en forma de granulado, el proceso que comprende los pasos de: proporcionar una mezcla que comprende ibuprofeno solido y una primera base seleccionada del grupo que consiste en hidroxido de sodio, hidroxido de potasio, carbonato de sodio, carbonato de potasio, glicinato de sodio, glicinato de potasio y fosfatos tribasicos de sodio y de potasio y mezclas de los anteriores, y hacer reaccionar el ibuprofeno y la primera base esencialmente en estado anhidro.
CR9424A 2005-12-23 2007-10-08 Ibuprofeno solubilizado CR9424A (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP05028321A EP1800667A1 (en) 2005-12-23 2005-12-23 Rapidly solubilizing ibuprofen granulate

Publications (1)

Publication Number Publication Date
CR9424A true CR9424A (es) 2008-01-21

Family

ID=35570762

Family Applications (1)

Application Number Title Priority Date Filing Date
CR9424A CR9424A (es) 2005-12-23 2007-10-08 Ibuprofeno solubilizado

Country Status (6)

Country Link
EP (1) EP1800667A1 (es)
AR (1) AR056469A1 (es)
CR (1) CR9424A (es)
GT (1) GT200600390A (es)
PE (1) PE20070765A1 (es)
TW (1) TW200738286A (es)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2353900T3 (es) * 2006-09-28 2011-03-08 Losan Pharma Gmbh Formulación de solubilización rápida de fármacos antiinflamatorios no esteroideos.
EP2309988B1 (en) 2008-07-21 2015-11-25 SI Group, Inc. High content sodium ibuprofen granules, their preparation and their use in preparing non-effervescent solid dosage forms
US9629809B2 (en) 2008-07-21 2017-04-25 Si Group, Inc. High content sodium ibuprofen granules, their preparation and their use in preparing non-effervescent solid dosage forms
GB2546513B (en) * 2016-01-20 2020-09-16 Cubic Pharmaceuticals Ltd Process of preparing active pharmaceutical ingredient salts

Family Cites Families (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1197038B (it) 1986-08-01 1988-11-25 Zambon Spa Composizione farmaceutica ad attivita' analgesica
US4859704A (en) 1987-10-15 1989-08-22 Oratech Pharmaceutical Development Corporation Water soluble ibuprofen compositions and methods of making them
FI89004C (fi) 1988-02-16 1993-08-10 Pertti J Neuvonen Anvaendning av tillsatsmedel foer oekning av absorptionshastigheten av laekemedel i orala laekemedelspreparat
DE3838431A1 (de) 1988-11-12 1990-05-17 Bayer Ag Ibuprofen-brausezubereitungen
DE3922441A1 (de) 1989-07-07 1991-01-17 Pharmatrans Sanaq Ag Ibuprofen- und s-(+)-ibuprofen-zubereitungen und verfahren zu ihrer herstellung
US5262179A (en) 1989-09-13 1993-11-16 Nicholas Kiwi Pty Ltd. Non-effervescent ibuprofen compositions
GB9224021D0 (en) 1992-11-16 1993-01-06 Boots Co Plc Effervescent compositions
DK0607467T3 (da) 1992-12-01 1999-12-13 Spirig Ag Lægemidler, der indeholder S(+)-ibuprofen
EP0667149A1 (en) * 1994-02-14 1995-08-16 E-PHARMA TRENTO S.p.A. Ibuprofen based effervescent composition
DE19509807A1 (de) 1995-03-21 1996-09-26 Basf Ag Verfahren zur Herstellung von Wirkstoffzubereitungen in Form einer festen Lösung des Wirkstoffs in einer Polymermatrix sowie mit diesem Verfahren hergestellte Wirkstoffzubereitungen
DE19606151C2 (de) 1996-02-20 1999-05-12 Losan Pharma Gmbh Ibuprofen-Brausezubereitung sowie Verfahren zur Herstellung derselben
GB9603699D0 (en) 1996-02-21 1996-04-17 Boots Co Plc Therapeutic composition
DE19733505A1 (de) 1997-08-01 1999-02-04 Knoll Ag Schnell wirksames Analgeticum
IT1301966B1 (it) 1998-07-30 2000-07-20 Zambon Spa Composizioni farmaceutiche ad attivita' analgesica
FR2785539B1 (fr) 1998-11-06 2004-04-09 Prographarm Laboratoires Particules enrobees d'ibuprofene cristallin granule
EP1305008A4 (en) 2001-03-27 2005-02-09 R P Scherer Technologies Inc A IMPROVED FORMS OF PHARMACEUTICALLY ACTIVE AGENTS AND PROCESS FOR THE PRODUCTION THEREOF
US20030008003A1 (en) 2001-04-10 2003-01-09 Fahkreddin Jamali Compositions for enhanced absorption of NSAIDs
CH693586A8 (de) 2002-10-14 2003-12-15 Roche Consumer Health Ag Darreichungsform von Ibuprofen-Natrium.

Also Published As

Publication number Publication date
EP1800667A1 (en) 2007-06-27
TW200738286A (en) 2007-10-16
GT200600390A (es) 2007-05-30
AR056469A1 (es) 2007-10-10
PE20070765A1 (es) 2007-08-10

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Legal Events

Date Code Title Description
FA Abandonment or withdrawal (granting procedure)