CR9595A - Derivados de benzofurarona como moduladores no esteroides de receptores de progesterona - Google Patents

Derivados de benzofurarona como moduladores no esteroides de receptores de progesterona

Info

Publication number
CR9595A
CR9595A CR9595A CR9595A CR9595A CR 9595 A CR9595 A CR 9595A CR 9595 A CR9595 A CR 9595A CR 9595 A CR9595 A CR 9595A CR 9595 A CR9595 A CR 9595A
Authority
CR
Costa Rica
Prior art keywords
benzofurarona
derivatives
progesterone receptors
steroid modulators
modulators
Prior art date
Application number
CR9595A
Other languages
English (en)
Inventor
Schwede Wolfgang
Moeller Carsten
Schmidt Anja
Fuhrmann Ulrike
Schmees Norbert
Bothe Ulrich
Original Assignee
Bayer Schering Pharma Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer Schering Pharma Ag filed Critical Bayer Schering Pharma Ag
Publication of CR9595A publication Critical patent/CR9595A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D307/87—Benzo [c] furans; Hydrogenated benzo [c] furans
    • C07D307/88—Benzo [c] furans; Hydrogenated benzo [c] furans with one oxygen atom directly attached in position 1 or 3
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/94—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom spiro-condensed with carbocyclic rings or ring systems, e.g. griseofulvins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/04—Drugs for genital or sexual disorders; Contraceptives for inducing labour or abortion; Uterotonics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/08—Drugs for genital or sexual disorders; Contraceptives for gonadal disorders or for enhancing fertility, e.g. inducers of ovulation or of spermatogenesis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/18—Feminine contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D307/78—Benzo [b] furans; Hydrogenated benzo [b] furans
    • C07D307/82—Benzo [b] furans; Hydrogenated benzo [b] furans with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the hetero ring
    • C07D307/83—Oxygen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D407/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00
    • C07D407/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings
    • C07D407/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Reproductive Health (AREA)
  • Endocrinology (AREA)
  • Gynecology & Obstetrics (AREA)
  • Pregnancy & Childbirth (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Steroid Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Furan Compounds (AREA)

Abstract

La presente invencion se refiere a moduladores no esteroides del receptor de progesterona de la formula general I, al proceso para su produccion, al uso de los moduladores del receptor de progesterona para la preparacion de agentes farmaceuticos asi como tambien composiciones farmaceuticas que contienen estos compuestos.
CR9595A 2005-06-24 2007-12-14 Derivados de benzofurarona como moduladores no esteroides de receptores de progesterona CR9595A (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE102005030294A DE102005030294A1 (de) 2005-06-24 2005-06-24 Nichtsteroidale Progesteronrezeptor-Modulatoren

Publications (1)

Publication Number Publication Date
CR9595A true CR9595A (es) 2008-05-05

Family

ID=36716643

Family Applications (1)

Application Number Title Priority Date Filing Date
CR9595A CR9595A (es) 2005-06-24 2007-12-14 Derivados de benzofurarona como moduladores no esteroides de receptores de progesterona

Country Status (22)

Country Link
EP (1) EP1899315A1 (es)
JP (1) JP2008543911A (es)
KR (1) KR20080018275A (es)
CN (1) CN101248056A (es)
AR (1) AR057409A1 (es)
AU (1) AU2006261049A1 (es)
BR (1) BRPI0612305A2 (es)
CA (1) CA2611900A1 (es)
CR (1) CR9595A (es)
DE (1) DE102005030294A1 (es)
DO (1) DOP2006000150A (es)
EA (1) EA200702604A1 (es)
EC (1) ECSP078043A (es)
GT (1) GT200600272A (es)
IL (1) IL188022A0 (es)
MX (1) MX2008000070A (es)
NO (1) NO20080441L (es)
PE (1) PE20070170A1 (es)
TW (1) TW200738665A (es)
UY (1) UY29626A1 (es)
WO (1) WO2006136462A1 (es)
ZA (1) ZA200800689B (es)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
UY30805A1 (es) * 2006-12-21 2008-07-31 Bayer Schering Pharma Ag Moduladores no esteroides de receptores de progesterona
DE102007032800A1 (de) * 2007-07-10 2009-01-15 Bayer Schering Pharma Aktiengesellschaft Nichtsteroidale Progesteronrezeptor-Modulatoren
DE102007058747A1 (de) * 2007-12-05 2009-06-10 Bayer Schering Pharma Aktiengesellschaft Nichtsteroidale Progesteronrezeptor-Modulatoren
TWI477276B (zh) * 2008-04-28 2015-03-21 Repros Therapeutics Inc 抗黃體素給藥方案
JP6341910B2 (ja) 2012-05-31 2018-06-13 レプロス セラピューティクス インコーポレイティド 抗プロゲスチンの経膣送達用製剤およびその送達方法
MX2015004821A (es) 2012-11-02 2015-08-14 Repros Therapeutics Inc Metodos y composiciones para tratar condiciones dependientes de la progesterona.

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE19723722A1 (de) * 1997-05-30 1998-12-10 Schering Ag Nichtsteroidale Gestagene
US6358948B1 (en) * 1999-05-04 2002-03-19 American Home Products Corporation Quinazolinone and benzoxazine derivatives as progesterone receptor modulators
WO2000066590A2 (en) * 1999-05-04 2000-11-09 Ligand Pharmaceuticals, Inc. Tetracyclic progesterone receptor modulator compounds and methods
ATE346058T1 (de) * 2002-01-14 2006-12-15 Boehringer Ingelheim Pharma Glucocorticoid mimetika, verfahren zu ihrer herstellung, pharmazeutische formulierungen sie enthaltend und verwendungen davon
WO2003075915A1 (en) * 2002-03-11 2003-09-18 Schering Ag 5-}2-hydroxy-3-`1-(3-trifluoromethylphenyl)-cyclopropyl!-propionylamino}- phtalide and related compounds with progesterone receptor modulating activity for use in fertility control and hormone replacement therapy
DE10346939A1 (de) * 2003-10-06 2005-05-19 Schering Ag Heterocyclisch substituierte Pentanole, ein Verfahren zu ihrer Herstellung und ihre Verwendung als Entzündungshemmer

Also Published As

Publication number Publication date
UY29626A1 (es) 2007-01-31
NO20080441L (no) 2008-03-07
BRPI0612305A2 (pt) 2010-11-03
EA200702604A1 (ru) 2008-06-30
AU2006261049A1 (en) 2006-12-28
WO2006136462A1 (en) 2006-12-28
CA2611900A1 (en) 2006-12-28
MX2008000070A (es) 2008-03-19
GT200600272A (es) 2007-08-20
ZA200800689B (en) 2009-07-29
TW200738665A (en) 2007-10-16
CN101248056A (zh) 2008-08-20
KR20080018275A (ko) 2008-02-27
DOP2006000150A (es) 2006-12-31
IL188022A0 (en) 2008-03-20
PE20070170A1 (es) 2007-03-02
AR057409A1 (es) 2007-12-05
EP1899315A1 (en) 2008-03-19
JP2008543911A (ja) 2008-12-04
ECSP078043A (es) 2008-01-23
DE102005030294A1 (de) 2007-01-04

Similar Documents

Publication Publication Date Title
CR10922A (es) Derivados de indol como antagonistas receptores de s1p1
SV2010003580A (es) Agonistas novedosos de los receptores de glucocorticoides
ECSP11011348A (es) 2-mercaptoquinolin-3-carboxamidas sustituidas como moduladores de kcnq2/3
CR9814A (es) Derivados de carboxamida como antagonistas del receptor muscarinico
ECSP088623A (es) Derivados de azepinoindol como agentes farmacéuticos
CR11623A (es) Compuestos
ECSP066856A (es) Compuestos novedosos como moduladores del receptor opioide
CR10497A (es) Derivados de piperazinilo utiles en el tratamiento de enfermedades mediadas por el receptor gpr38
ECSP099338A (es) Derivados de quiniclidina de ácido (hetero) arilcicloheptano carboxíclico como antagonistas del receptor muscarínico
CO6351723A2 (es) Derivados de pirazolo-[5,1-b]-oxazol como antagonistas de crf1
UY32744A (es) Derivados de 2-carboxamida-7-piperazinil-benzofurano 774
CR20190379A (es) Moduladores del receptor de estrógeno
ECSP11011345A (es) 2-mercapto-3-aminopiridina sustituida como moduladores de kcnq2/3
ECSP11011346A (es) 3-Amino-2-mercaptoquinolina sustituida como modulador de KCNQ2/3
CR9595A (es) Derivados de benzofurarona como moduladores no esteroides de receptores de progesterona
CR11171A (es) Nuevos compuestos ligandos del receptor de la adenosina a3
NI201100015A (es) Compuestos novedosos activos como antagonistas de receptor muscarínico.
ECSP10010200A (es) Derivados de pirazol como inhibidores de 5-lo
UY31338A1 (es) Compuestos novedosos activos como antagonistas de receptores muscarinicos
ECSP067028A (es) Profármacos de esteroides con acción androgénica
UY31428A1 (es) Derivados 1,2,4-triazol tiofeno fusionados como moduladores de mglur5
UY29817A1 (es) Nuevos compuestos de azetidina, composiciones farmacéuticas que los contienen, procesos de preparación y uso terapéutico de los mismos.
CU23564A3 (es) Derivados de carboxamida como antagonistas del receptor muscarínico
CR11790A (es) Derivados de quinuclidina como antagonistas de receptores muscarinicos m3

Legal Events

Date Code Title Description
FA Abandonment or withdrawal (granting procedure)