CR9595A - BENZOFURARONA DERIVATIVES AS NON-STEROID MODULATORS OF PROGESTERONE RECEPTORS - Google Patents
BENZOFURARONA DERIVATIVES AS NON-STEROID MODULATORS OF PROGESTERONE RECEPTORSInfo
- Publication number
- CR9595A CR9595A CR9595A CR9595A CR9595A CR 9595 A CR9595 A CR 9595A CR 9595 A CR9595 A CR 9595A CR 9595 A CR9595 A CR 9595A CR 9595 A CR9595 A CR 9595A
- Authority
- CR
- Costa Rica
- Prior art keywords
- benzofurarona
- derivatives
- progesterone receptors
- steroid modulators
- modulators
- Prior art date
Links
- 102000003998 progesterone receptors Human genes 0.000 title 1
- 108090000468 progesterone receptors Proteins 0.000 title 1
- 239000002379 progesterone receptor modulator Substances 0.000 abstract 2
- 229940095745 sex hormone and modulator of the genital system progesterone receptor modulator Drugs 0.000 abstract 2
- 150000001875 compounds Chemical class 0.000 abstract 1
- 238000004519 manufacturing process Methods 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 239000008177 pharmaceutical agent Substances 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 230000003637 steroidlike Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D307/87—Benzo [c] furans; Hydrogenated benzo [c] furans
- C07D307/88—Benzo [c] furans; Hydrogenated benzo [c] furans with one oxygen atom directly attached in position 1 or 3
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/94—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom spiro-condensed with carbocyclic rings or ring systems, e.g. griseofulvins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/04—Drugs for genital or sexual disorders; Contraceptives for inducing labour or abortion; Uterotonics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/08—Drugs for genital or sexual disorders; Contraceptives for gonadal disorders or for enhancing fertility, e.g. inducers of ovulation or of spermatogenesis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/18—Feminine contraceptives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D307/78—Benzo [b] furans; Hydrogenated benzo [b] furans
- C07D307/82—Benzo [b] furans; Hydrogenated benzo [b] furans with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the hetero ring
- C07D307/83—Oxygen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D407/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00
- C07D407/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings
- C07D407/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Reproductive Health (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Endocrinology (AREA)
- Gynecology & Obstetrics (AREA)
- Pregnancy & Childbirth (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Steroid Compounds (AREA)
- Furan Compounds (AREA)
Abstract
La presente invencion se refiere a moduladores no esteroides del receptor de progesterona de la formula general I, al proceso para su produccion, al uso de los moduladores del receptor de progesterona para la preparacion de agentes farmaceuticos asi como tambien composiciones farmaceuticas que contienen estos compuestos.The present invention relates to non-steroidal progesterone receptor modulators of the general formula I, to the process for their production, to the use of progesterone receptor modulators for the preparation of pharmaceutical agents as well as pharmaceutical compositions containing these compounds.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE102005030294A DE102005030294A1 (en) | 2005-06-24 | 2005-06-24 | Nonsteroidal progesterone receptor modulators |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CR9595A true CR9595A (en) | 2008-05-05 |
Family
ID=36716643
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CR9595A CR9595A (en) | 2005-06-24 | 2007-12-14 | BENZOFURARONA DERIVATIVES AS NON-STEROID MODULATORS OF PROGESTERONE RECEPTORS |
Country Status (22)
| Country | Link |
|---|---|
| EP (1) | EP1899315A1 (en) |
| JP (1) | JP2008543911A (en) |
| KR (1) | KR20080018275A (en) |
| CN (1) | CN101248056A (en) |
| AR (1) | AR057409A1 (en) |
| AU (1) | AU2006261049A1 (en) |
| BR (1) | BRPI0612305A2 (en) |
| CA (1) | CA2611900A1 (en) |
| CR (1) | CR9595A (en) |
| DE (1) | DE102005030294A1 (en) |
| DO (1) | DOP2006000150A (en) |
| EA (1) | EA200702604A1 (en) |
| EC (1) | ECSP078043A (en) |
| GT (1) | GT200600272A (en) |
| IL (1) | IL188022A0 (en) |
| MX (1) | MX2008000070A (en) |
| NO (1) | NO20080441L (en) |
| PE (1) | PE20070170A1 (en) |
| TW (1) | TW200738665A (en) |
| UY (1) | UY29626A1 (en) |
| WO (1) | WO2006136462A1 (en) |
| ZA (1) | ZA200800689B (en) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| UY30805A1 (en) * | 2006-12-21 | 2008-07-31 | Bayer Schering Pharma Ag | NON-STEROID MODULATORS OF PROGESTERONE RECEPTORS |
| DE102007032800A1 (en) * | 2007-07-10 | 2009-01-15 | Bayer Schering Pharma Aktiengesellschaft | Nonsteroidal progesterone receptor modulators |
| DE102007058747A1 (en) | 2007-12-05 | 2009-06-10 | Bayer Schering Pharma Aktiengesellschaft | Nonsteroidal progesterone receptor modulators |
| TWI477276B (en) | 2008-04-28 | 2015-03-21 | Repros Therapeutics Inc | Antiprogestin dosing regimens |
| CA2872644A1 (en) | 2012-05-31 | 2013-12-05 | Allergan Pharmaceuticals International Limited | Formulations and methods for vaginal delivery of antiprogestins |
| US9545411B2 (en) | 2012-11-02 | 2017-01-17 | Repros Therapeutics Inc. | Methods and compositions for treating progesterone-dependent conditions |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE19723722A1 (en) * | 1997-05-30 | 1998-12-10 | Schering Ag | Nonsteroidal progestogens |
| US6358948B1 (en) * | 1999-05-04 | 2002-03-19 | American Home Products Corporation | Quinazolinone and benzoxazine derivatives as progesterone receptor modulators |
| AU4501800A (en) * | 1999-05-04 | 2000-11-17 | American Home Products Corporation | Tetracyclic progesterone receptor modulator compounds and methods |
| EP1467982B8 (en) * | 2002-01-14 | 2007-04-11 | Boehringer Ingelheim Pharmaceuticals Inc. | Glucocorticoid mimetics, methods of making them, pharmaceutical formulations containing them, and uses thereof |
| DK1482925T3 (en) * | 2002-03-11 | 2007-05-14 | Bayer Schering Pharma Ag | 5- (2-Hydroxy-3- (1- (3-trifluoromethylphenyl) cyclopropylpropionylamino) phthalide and related compounds with progesterone receptor modulating activity for use in fertility control and hormone replacement therapy |
| DE10346939A1 (en) * | 2003-10-06 | 2005-05-19 | Schering Ag | New arylalkanol derivatives used for treating e.g. respiratory diseases, joint diseases, vascular inflammations, skin disorders, kidney and liver diseases and neurological diseases |
-
2005
- 2005-06-24 DE DE102005030294A patent/DE102005030294A1/en not_active Ceased
-
2006
- 2006-06-22 BR BRPI0612305-8A patent/BRPI0612305A2/en not_active Application Discontinuation
- 2006-06-22 CA CA002611900A patent/CA2611900A1/en not_active Abandoned
- 2006-06-22 JP JP2008517445A patent/JP2008543911A/en active Pending
- 2006-06-22 EP EP06762405A patent/EP1899315A1/en not_active Withdrawn
- 2006-06-22 KR KR1020087001789A patent/KR20080018275A/en not_active Withdrawn
- 2006-06-22 MX MX2008000070A patent/MX2008000070A/en not_active Application Discontinuation
- 2006-06-22 CN CNA2006800306699A patent/CN101248056A/en active Pending
- 2006-06-22 AU AU2006261049A patent/AU2006261049A1/en not_active Abandoned
- 2006-06-22 EA EA200702604A patent/EA200702604A1/en unknown
- 2006-06-22 WO PCT/EP2006/006532 patent/WO2006136462A1/en not_active Ceased
- 2006-06-23 TW TW095122741A patent/TW200738665A/en unknown
- 2006-06-26 PE PE2006000732A patent/PE20070170A1/en not_active Application Discontinuation
- 2006-06-26 UY UY29626A patent/UY29626A1/en not_active Application Discontinuation
- 2006-06-26 GT GT200600272A patent/GT200600272A/en unknown
- 2006-06-26 DO DO2006000150A patent/DOP2006000150A/en unknown
- 2006-06-27 AR ARP060102752A patent/AR057409A1/en unknown
-
2007
- 2007-12-10 IL IL188022A patent/IL188022A0/en unknown
- 2007-12-14 CR CR9595A patent/CR9595A/en not_active Application Discontinuation
- 2007-12-21 EC EC2007008043A patent/ECSP078043A/en unknown
-
2008
- 2008-01-23 NO NO20080441A patent/NO20080441L/en not_active Application Discontinuation
- 2008-01-23 ZA ZA200800689A patent/ZA200800689B/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| KR20080018275A (en) | 2008-02-27 |
| AR057409A1 (en) | 2007-12-05 |
| BRPI0612305A2 (en) | 2010-11-03 |
| AU2006261049A1 (en) | 2006-12-28 |
| EP1899315A1 (en) | 2008-03-19 |
| JP2008543911A (en) | 2008-12-04 |
| EA200702604A1 (en) | 2008-06-30 |
| DOP2006000150A (en) | 2006-12-31 |
| NO20080441L (en) | 2008-03-07 |
| PE20070170A1 (en) | 2007-03-02 |
| DE102005030294A1 (en) | 2007-01-04 |
| WO2006136462A1 (en) | 2006-12-28 |
| ECSP078043A (en) | 2008-01-23 |
| CA2611900A1 (en) | 2006-12-28 |
| GT200600272A (en) | 2007-08-20 |
| UY29626A1 (en) | 2007-01-31 |
| ZA200800689B (en) | 2009-07-29 |
| TW200738665A (en) | 2007-10-16 |
| CN101248056A (en) | 2008-08-20 |
| IL188022A0 (en) | 2008-03-20 |
| MX2008000070A (en) | 2008-03-19 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FA | Abandonment or withdrawal (granting procedure) |