CR9606A - Anticuerpos anti-proteina quinoatrayente de monocitos-1, composiciones, metodos y usos - Google Patents

Anticuerpos anti-proteina quinoatrayente de monocitos-1, composiciones, metodos y usos

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Publication number
CR9606A
CR9606A CR9606A CR9606A CR9606A CR 9606 A CR9606 A CR 9606A CR 9606 A CR9606 A CR 9606A CR 9606 A CR9606 A CR 9606A CR 9606 A CR9606 A CR 9606A
Authority
CR
Costa Rica
Prior art keywords
methods
compositions
quinoatrayente
monocits
antibodies
Prior art date
Application number
CR9606A
Other languages
English (en)
Inventor
Das Anuk
Sweet Raymond
Tsui Ping
Bardroff Michael
Original Assignee
Centocor Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Centocor Inc filed Critical Centocor Inc
Publication of CR9606A publication Critical patent/CR9606A/es

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/24—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
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    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
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    • C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding
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    • C07K2317/77—Internalization into the cell
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    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
    • C07K2317/92—Affinity (KD), association rate (Ka), dissociation rate (Kd) or EC50 value

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Abstract

La presente invencion se refiere a por lo menos un anticuerpo anti-MCP-1 novedoso, que incluye acidos nucleicos aislados que codifican por lo menos un anticuerpo anti-MCP-1, vectores, celulas hospedero, animales o plantas transgenicos, y metodos para hacer y usar los mismos, incluyendo composiciones, metodos y dispositivos terapeuticos.
CR9606A 2005-05-19 2007-12-18 Anticuerpos anti-proteina quinoatrayente de monocitos-1, composiciones, metodos y usos CR9606A (es)

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EP2481408A3 (en) 2007-03-01 2013-01-09 Probiodrug AG New use of glutaminyl cyclase inhibitors
WO2008128985A1 (en) 2007-04-18 2008-10-30 Probiodrug Ag Thiourea derivatives as glutaminyl cyclase inhibitors
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DK2328930T3 (da) 2008-08-20 2015-03-30 Probiodrug Ag Antistoffer rettet mod pyroglutamat-monocyt-kemoattraktant-protein-1 (mcp-1N1pE)
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CN104487091A (zh) * 2012-05-22 2015-04-01 夏尔人类遗传性治疗公司 用于治疗硬皮病的抗ccl2抗体
EP2727944A1 (en) * 2012-10-30 2014-05-07 Universitätsklinikum Regensburg Depletion of CCR2-positive monocytes for the treatment of inflammatory conditions in the gastrointestinal system
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WO2022263501A1 (en) * 2021-06-18 2022-12-22 F. Hoffmann-La Roche Ag Bispecific anti-ccl2 antibodies
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AU2010202813B2 (en) 2011-11-03
AR053470A1 (es) 2007-05-09
IL187459A0 (en) 2008-03-20
NZ563516A (en) 2011-04-29
EA200702532A1 (ru) 2008-06-30
CA2609349A1 (en) 2006-11-23
AU2006247034A1 (en) 2006-11-23
EP1888114B1 (en) 2013-09-18
NO20076563L (no) 2008-02-05
CN101511869B (zh) 2012-12-12
EP1888114A4 (en) 2010-02-24
PE20061444A1 (es) 2007-01-15
AU2010202813A1 (en) 2010-07-22
KR100977823B1 (ko) 2010-08-25
ZA200711073B (en) 2009-09-30
ES2438193T3 (es) 2014-01-16
WO2006125202A3 (en) 2009-05-07
WO2006125202A2 (en) 2006-11-23
JP2008546374A (ja) 2008-12-25
CA2609349C (en) 2012-10-30
BRPI0613164A2 (pt) 2010-12-21
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