CS122288A2 - Method of 8-(4-(4-(2-pyrimidinyl)-1-piperazinyl) butyl)-8-aza-spiro (4,5)-decane-7,9-dione preparation - Google Patents
Method of 8-(4-(4-(2-pyrimidinyl)-1-piperazinyl) butyl)-8-aza-spiro (4,5)-decane-7,9-dione preparationInfo
- Publication number
- CS122288A2 CS122288A2 CS881222A CS122288A CS122288A2 CS 122288 A2 CS122288 A2 CS 122288A2 CS 881222 A CS881222 A CS 881222A CS 122288 A CS122288 A CS 122288A CS 122288 A2 CS122288 A2 CS 122288A2
- Authority
- CS
- Czechoslovakia
- Prior art keywords
- aza
- decane
- piperazinyl
- spiro
- pyrimidinyl
- Prior art date
Links
- QWCRAEMEVRGPNT-UHFFFAOYSA-N buspirone Chemical compound C1C(=O)N(CCCCN2CCN(CC2)C=2N=CC=CN=2)C(=O)CC21CCCC2 QWCRAEMEVRGPNT-UHFFFAOYSA-N 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| HU71687A HU197313B (en) | 1987-02-25 | 1987-02-25 | Process for producing 8-azaspiro <4.5> decane-7,9-dione-8-propine-/2/ |
| HU71887A HU198477B (en) | 1987-02-25 | 1987-02-25 | Process for producing pyrimidinyl piperazine derivatives |
| HU71787A HU198204B (en) | 1987-02-25 | 1987-02-25 | Process for production of derivatives of piperasine |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CS122288A2 true CS122288A2 (en) | 1990-08-14 |
| CS274423B2 CS274423B2 (en) | 1991-04-11 |
Family
ID=27269942
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CS122288A CS274423B2 (en) | 1987-02-25 | 1988-02-25 | Method of 8-(4-(4-(2-pyrimidinyl)-1-piperazinyl) butyl)-8-aza-spiro (4,5)-decane-7,9-dione preparation |
Country Status (20)
| Country | Link |
|---|---|
| KR (1) | KR880009955A (en) |
| CN (1) | CN88100923A (en) |
| AT (1) | AT395851B (en) |
| BE (1) | BE1001464A3 (en) |
| CA (1) | CA1300141C (en) |
| CH (1) | CH677924A5 (en) |
| CS (1) | CS274423B2 (en) |
| DE (1) | DE3806009C2 (en) |
| DK (1) | DK99388A (en) |
| ES (1) | ES2009236A6 (en) |
| FI (1) | FI880895A7 (en) |
| FR (1) | FR2615853B1 (en) |
| GB (1) | GB2201417B (en) |
| GR (1) | GR1002245B (en) |
| IL (1) | IL85545A (en) |
| IT (1) | IT1217342B (en) |
| NL (1) | NL8800484A (en) |
| PL (1) | PL152958B1 (en) |
| SE (1) | SE8800651L (en) |
| YU (1) | YU46441B (en) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| HU217129B (en) * | 1993-07-16 | 1999-11-29 | EGIS Gyógyszergyár Rt. | Process for the preparation of buspiron as therapeutical active ingredient of high purity |
| KR950014099A (en) * | 1993-11-10 | 1995-06-15 | 장기하 | Method for preparing N- (2-pyrimidyl) piperazinyl butylamide |
| CN119409681B (en) * | 2024-03-28 | 2025-12-16 | 北京华素制药股份有限公司 | Preparation method of buspirone hydrochloride |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE1545543B1 (en) * | 1964-07-03 | 1970-01-22 | Astra Apotekarnes Kem Fab | 4-aminobutinylimides, their salts and processes for their preparation |
| SE300422B (en) * | 1964-07-03 | 1968-04-29 | Astra Ab | |
| US3354178A (en) * | 1965-04-09 | 1967-11-21 | Sterling Drug Inc | Nu-(4-amino-2-butynyl)-nu-alkylcarboxamides |
| BE759371A (en) * | 1969-11-24 | 1971-05-24 | Bristol Myers Co | HETEROCYCLICAL AZASPIRODECANEDIONES AND METHODS FOR THEIR PREPARATION |
| JPS6310786A (en) * | 1986-07-01 | 1988-01-18 | Sumitomo Pharmaceut Co Ltd | Novel imide derivative and production thereof |
| JPS6310760A (en) * | 1986-07-01 | 1988-01-18 | Sumitomo Pharmaceut Co Ltd | Novel production of imide derivative |
-
1988
- 1988-02-23 CH CH675/88A patent/CH677924A5/de not_active IP Right Cessation
- 1988-02-23 PL PL1988270815A patent/PL152958B1/en unknown
- 1988-02-24 CN CN198888100923A patent/CN88100923A/en active Pending
- 1988-02-25 IL IL85545A patent/IL85545A/en not_active IP Right Cessation
- 1988-02-25 GR GR880100108A patent/GR1002245B/en unknown
- 1988-02-25 YU YU36288A patent/YU46441B/en unknown
- 1988-02-25 AT AT0047688A patent/AT395851B/en not_active IP Right Cessation
- 1988-02-25 NL NL8800484A patent/NL8800484A/en not_active Application Discontinuation
- 1988-02-25 KR KR1019880001939A patent/KR880009955A/en not_active Ceased
- 1988-02-25 SE SE8800651A patent/SE8800651L/en not_active Application Discontinuation
- 1988-02-25 DE DE3806009A patent/DE3806009C2/en not_active Expired - Fee Related
- 1988-02-25 IT IT19545/88A patent/IT1217342B/en active
- 1988-02-25 ES ES8800543A patent/ES2009236A6/en not_active Expired
- 1988-02-25 DK DK099388A patent/DK99388A/en not_active Application Discontinuation
- 1988-02-25 GB GB8804385A patent/GB2201417B/en not_active Expired - Lifetime
- 1988-02-25 CA CA000559846A patent/CA1300141C/en not_active Expired - Lifetime
- 1988-02-25 CS CS122288A patent/CS274423B2/en unknown
- 1988-02-25 BE BE8800218A patent/BE1001464A3/en not_active IP Right Cessation
- 1988-02-25 FI FI880895A patent/FI880895A7/en not_active Application Discontinuation
- 1988-02-25 FR FR888802286A patent/FR2615853B1/en not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| FI880895A0 (en) | 1988-02-25 |
| DE3806009A1 (en) | 1988-09-08 |
| GR880100108A (en) | 1988-12-16 |
| DK99388A (en) | 1988-08-26 |
| FI880895A7 (en) | 1988-08-26 |
| IL85545A (en) | 1992-05-25 |
| GB2201417A (en) | 1988-09-01 |
| GB8804385D0 (en) | 1988-03-23 |
| ES2009236A6 (en) | 1989-09-16 |
| ATA47688A (en) | 1992-08-15 |
| CA1300141C (en) | 1992-05-05 |
| DE3806009C2 (en) | 1996-09-12 |
| GR1002245B (en) | 1996-04-22 |
| AT395851B (en) | 1993-03-25 |
| PL270815A1 (en) | 1989-04-03 |
| SE8800651D0 (en) | 1988-02-25 |
| IT8819545A0 (en) | 1988-02-25 |
| CH677924A5 (en) | 1991-07-15 |
| CS274423B2 (en) | 1991-04-11 |
| FR2615853B1 (en) | 1991-01-04 |
| NL8800484A (en) | 1988-09-16 |
| DK99388D0 (en) | 1988-02-25 |
| SE8800651L (en) | 1988-08-26 |
| PL152958B1 (en) | 1991-02-28 |
| YU36288A (en) | 1989-10-31 |
| FR2615853A1 (en) | 1988-12-02 |
| GB2201417B (en) | 1990-10-31 |
| YU46441B (en) | 1993-10-20 |
| IL85545A0 (en) | 1988-08-31 |
| IT1217342B (en) | 1990-03-22 |
| KR880009955A (en) | 1988-10-06 |
| CN88100923A (en) | 1988-09-28 |
| BE1001464A3 (en) | 1989-11-07 |
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